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The map label for this gene is ung [H]

Identifier: 71892316

GI number: 71892316

Start: 673829

End: 674521

Strand: Direct

Name: ung [H]

Synonym: BPEN_563

Alternate gene names: 71892316

Gene position: 673829-674521 (Clockwise)

Preceding gene: 71892308

Following gene: 71892318

Centisome position: 85.12

GC content: 31.89

Gene sequence:

>693_bases
GTGCCTCAAAAATTAAATTGGCGGTTTTTGTTATCAAAAGAAAAAACATTGCCGTACTTTCAGAATATATTGTTTGCCAT
AGAGGAACGTAAAAAAAAAGGTATTACGATTTATCCTAAAAAAAAAGATGTTTTTAACGCGTTTCGTTTTACTAGTTTTG
AATCTATAAAAGTTGTTATTATAGGCCAAGATCCTTATCATGGACCAAATCAAGCCCATGGATTTGCCTTTTCTGTATTG
CCTGGTGTTTTGCCTCCTCCTTCTTTAAAAAATATTTATAAAGAGCTTGCATCTGATATGCCCGATTTTGTAATACCAGA
ACACGGTTGTTTAGAGAGTTGGGCGCAAGAAGGGGTGTTATTGCTTAATAGTATTTTAACTGTTGAGGAAGGAAGAAGTT
GTTCTCATGCTGATATTGGATGGGAACGATTTACAGACAAAATAATATCTATACTGAACACACATAAGGAAAAAATTATA
TTTTTACTATGGGGAAAATATGCTCAAAACAAAGGCAACATCATTAACCATAAAAAACATTATATTTTCACTGCGTCACA
TCCTTCACCTATATCAGCTCAACGTGGATTTTTAGGATGTCATCATTTTTCTAAGGTTAATATATTATTAGCGCAACAAA
ATAAACAGATTATTAATTGGCAACCTAAAATAATTGACTCAAAACTAATATAA

Upstream 100 bases:

>100_bases
TATGTGTTTAAATACATAATTTTTTTGGTAATCAATAAAAAACATCAATGATAAGTGAAAATTTTATTTGTACGATTACA
TAATAATACGGAAATAAACC

Downstream 100 bases:

>100_bases
ATTAAAAATATGTTATGAAGGATGATTTCTTTCATGTAAATTTATTTATTTTATATCTTGTACTCTTGAATATCATTGTT
GATTTATTGTGATAAATCAA

Product: uracil-DNA glycosylase

Products: NA

Alternate protein names: UDG [H]

Number of amino acids: Translated: 230; Mature: 229

Protein sequence:

>230_residues
MPQKLNWRFLLSKEKTLPYFQNILFAIEERKKKGITIYPKKKDVFNAFRFTSFESIKVVIIGQDPYHGPNQAHGFAFSVL
PGVLPPPSLKNIYKELASDMPDFVIPEHGCLESWAQEGVLLLNSILTVEEGRSCSHADIGWERFTDKIISILNTHKEKII
FLLWGKYAQNKGNIINHKKHYIFTASHPSPISAQRGFLGCHHFSKVNILLAQQNKQIINWQPKIIDSKLI

Sequences:

>Translated_230_residues
MPQKLNWRFLLSKEKTLPYFQNILFAIEERKKKGITIYPKKKDVFNAFRFTSFESIKVVIIGQDPYHGPNQAHGFAFSVL
PGVLPPPSLKNIYKELASDMPDFVIPEHGCLESWAQEGVLLLNSILTVEEGRSCSHADIGWERFTDKIISILNTHKEKII
FLLWGKYAQNKGNIINHKKHYIFTASHPSPISAQRGFLGCHHFSKVNILLAQQNKQIINWQPKIIDSKLI
>Mature_229_residues
PQKLNWRFLLSKEKTLPYFQNILFAIEERKKKGITIYPKKKDVFNAFRFTSFESIKVVIIGQDPYHGPNQAHGFAFSVLP
GVLPPPSLKNIYKELASDMPDFVIPEHGCLESWAQEGVLLLNSILTVEEGRSCSHADIGWERFTDKIISILNTHKEKIIF
LLWGKYAQNKGNIINHKKHYIFTASHPSPISAQRGFLGCHHFSKVNILLAQQNKQIINWQPKIIDSKLI

Specific function: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine [H]

COG id: COG0692

COG function: function code L; Uracil DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uracil-DNA glycosylase family [H]

Homologues:

Organism=Homo sapiens, GI19718751, Length=217, Percent_Identity=51.6129032258064, Blast_Score=234, Evalue=5e-62,
Organism=Homo sapiens, GI6224979, Length=217, Percent_Identity=51.6129032258064, Blast_Score=233, Evalue=8e-62,
Organism=Escherichia coli, GI1788934, Length=222, Percent_Identity=55.8558558558559, Blast_Score=280, Evalue=7e-77,
Organism=Caenorhabditis elegans, GI17556304, Length=216, Percent_Identity=47.2222222222222, Blast_Score=200, Evalue=4e-52,
Organism=Saccharomyces cerevisiae, GI6323620, Length=220, Percent_Identity=42.2727272727273, Blast_Score=165, Evalue=7e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002043
- InterPro:   IPR018085
- InterPro:   IPR005122 [H]

Pfam domain/function: PF03167 UDG [H]

EC number: =3.2.2.27 [H]

Molecular weight: Translated: 26407; Mature: 26276

Theoretical pI: Translated: 10.03; Mature: 10.03

Prosite motif: PS00130 U_DNA_GLYCOSYLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQKLNWRFLLSKEKTLPYFQNILFAIEERKKKGITIYPKKKDVFNAFRFTSFESIKVVI
CCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHCCCCCCEEEEE
IGQDPYHGPNQAHGFAFSVLPGVLPPPSLKNIYKELASDMPDFVIPEHGCLESWAQEGVL
EECCCCCCCCCCCCEEHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCHH
LLNSILTVEEGRSCSHADIGWERFTDKIISILNTHKEKIIFLLWGKYAQNKGNIINHKKH
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCEECCCEE
YIFTASHPSPISAQRGFLGCHHFSKVNILLAQQNKQIINWQPKIIDSKLI
EEEECCCCCCCCCCCCCEEECCCCEEEEEEEECCCEEECCCCCHHCCCCC
>Mature Secondary Structure 
PQKLNWRFLLSKEKTLPYFQNILFAIEERKKKGITIYPKKKDVFNAFRFTSFESIKVVI
CCCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCEEEECCCHHHHHHHHCCCCCCEEEEE
IGQDPYHGPNQAHGFAFSVLPGVLPPPSLKNIYKELASDMPDFVIPEHGCLESWAQEGVL
EECCCCCCCCCCCCEEHHHCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCHH
LLNSILTVEEGRSCSHADIGWERFTDKIISILNTHKEKIIFLLWGKYAQNKGNIINHKKH
HHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCEECCCEE
YIFTASHPSPISAQRGFLGCHHFSKVNILLAQQNKQIINWQPKIIDSKLI
EEEECCCCCCCCCCCCCEEECCCCEEEEEEEECCCEEECCCCCHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA