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The map label for this gene is nuoN

Identifier: 71892254

GI number: 71892254

Start: 594648

End: 596141

Strand: Reverse

Name: nuoN

Synonym: BPEN_497

Alternate gene names: 71892254

Gene position: 596141-594648 (Counterclockwise)

Preceding gene: 71892255

Following gene: 71892249

Centisome position: 75.3

GC content: 28.92

Gene sequence:

>1494_bases
ATGCTAATAACTTGGACGCACATAATTCTATTGCTGCCTATACTAATTATTGGAATGACAACCGTTATTGTTATGTTATC
TATTGCATATCGTCGTAATTTATTTTTACATACTTCATTAACAATATTCGGATTTAGTTTAGCAATTATATCGGTTGGAT
TAGTATGGGATCAAAGAGATCGAAACTTTTTGCAATTAATATGTGTTGATGATTTTTCTATATTATACATAATATTGGTG
TTAGTTTCTGGTTTATCAAGTTCTGTATTGGCTTATAAATGGTTGTTAATTTATCCGAGTAATAATCGTGACGAGTTTTA
TTTATTATTACTTATTTCTAGTATTGGCGGTATTTTACTAGCAACTACGAATCATTTAGTAATATTATTTTTAGGAATGG
AACTGATTTCGTTGCCGTTATTTGGGCTGATAGGTTATTCTTTTTTTAACAAATTTTCTTTAGAGGCAAGTATTAAATAT
ATTATATTATCTGGAGTATCTTCATCATTTATATTATTTGGTATAGCATTGATATATGCTGCAACTGGTTTTTTGTCTTT
TACTAGTATTAGTCAATTATTACGTTTACATATTATTGCGTCGAATCAATCTATATTTATGTCAACCATAGGACTAGGTA
TGATGATGGTTGGGTTCGGTTTTAAATTGTCATTAGTTCCTTTTCATTTATGGACTCCTGATGTATATCAAGGAGCACCA
TCTTCAATATCATTGTATCTGACAACTAGCAGTAAAATAGCTGTAATATCTGTATTGATACGATTATTGATGGTGTTTCC
TAATCAGTATAATACGGTATTTTGTATATTTTTATTAGGTATTGCATGTTGCTCAGCGTTATTCGGCAATTTAATGGCTA
TTAAACAAGATAATATTAAGCGTGTTTTAGCTTATTCTTCAATTGCACATACAGGTTATGTTTTAATTGGTGTTATTGCA
ATATTACGGGTCAACCACCCCATGGCTTTGGAAACTATTGGTATTTATCTTATAAGTTACGTTCTGACTAGTATTGGTGC
ATTTGGTATTATCAATATAGTATCTTTTTTTTATGCCCATGAGGACACAGACGTAGATTCTTTGTTTGTATATCGTGGTC
TTTTTTGGCATCAGCCAATGTTATCGGTATTATTTACGATTATTATATTGTCTTTAGCGGGAATACCTATGACATTAGGT
TTCATTGGGAAATTTTATTTGTTTGTTTTGGGAATAGACAGTAAATTATGGTGGTTTACTATTTTTATAGCAATGAGTAG
TGTTATTAGTATATTTTATTATTTAAGAATTATAATAAATTTATATCTTAGTCCTATAAATCGTTTAAATATCAACTCTG
ATTTTTTATCTAGTTGGAGTGTTACTCCTGATAAGATAATAGTGATTATAGTATCTTTTTCTATATTATTTTTAGGATTA
TATCCAAAGCCTTTGATTTATTTTATGCATCTAATATATCCACCGGTACTTTAA

Upstream 100 bases:

>100_bases
GAATGTTTCATATATGACAATGCACAATCTTTGTCTTTTTTTAAAAGAATATAACTGTTCAATGTGATTACATTATAACG
ATATAGGATCTTGATTTGTT

Downstream 100 bases:

>100_bases
TTGAAATATAAATGTAATCGGAGGATTTTACATTTTAAATTATTTAACGAATGATTTTATGAGTTTGTGAATTTATAATA
ATGTCGTTTAAAACACGTGT

Product: NADH dehydrogenase I chain N, membrane subunit

Products: NA

Alternate protein names: NADH dehydrogenase I subunit N; NDH-1 subunit N

Number of amino acids: Translated: 497; Mature: 497

Protein sequence:

>497_residues
MLITWTHIILLLPILIIGMTTVIVMLSIAYRRNLFLHTSLTIFGFSLAIISVGLVWDQRDRNFLQLICVDDFSILYIILV
LVSGLSSSVLAYKWLLIYPSNNRDEFYLLLLISSIGGILLATTNHLVILFLGMELISLPLFGLIGYSFFNKFSLEASIKY
IILSGVSSSFILFGIALIYAATGFLSFTSISQLLRLHIIASNQSIFMSTIGLGMMMVGFGFKLSLVPFHLWTPDVYQGAP
SSISLYLTTSSKIAVISVLIRLLMVFPNQYNTVFCIFLLGIACCSALFGNLMAIKQDNIKRVLAYSSIAHTGYVLIGVIA
ILRVNHPMALETIGIYLISYVLTSIGAFGIINIVSFFYAHEDTDVDSLFVYRGLFWHQPMLSVLFTIIILSLAGIPMTLG
FIGKFYLFVLGIDSKLWWFTIFIAMSSVISIFYYLRIIINLYLSPINRLNINSDFLSSWSVTPDKIIVIIVSFSILFLGL
YPKPLIYFMHLIYPPVL

Sequences:

>Translated_497_residues
MLITWTHIILLLPILIIGMTTVIVMLSIAYRRNLFLHTSLTIFGFSLAIISVGLVWDQRDRNFLQLICVDDFSILYIILV
LVSGLSSSVLAYKWLLIYPSNNRDEFYLLLLISSIGGILLATTNHLVILFLGMELISLPLFGLIGYSFFNKFSLEASIKY
IILSGVSSSFILFGIALIYAATGFLSFTSISQLLRLHIIASNQSIFMSTIGLGMMMVGFGFKLSLVPFHLWTPDVYQGAP
SSISLYLTTSSKIAVISVLIRLLMVFPNQYNTVFCIFLLGIACCSALFGNLMAIKQDNIKRVLAYSSIAHTGYVLIGVIA
ILRVNHPMALETIGIYLISYVLTSIGAFGIINIVSFFYAHEDTDVDSLFVYRGLFWHQPMLSVLFTIIILSLAGIPMTLG
FIGKFYLFVLGIDSKLWWFTIFIAMSSVISIFYYLRIIINLYLSPINRLNINSDFLSSWSVTPDKIIVIIVSFSILFLGL
YPKPLIYFMHLIYPPVL
>Mature_497_residues
MLITWTHIILLLPILIIGMTTVIVMLSIAYRRNLFLHTSLTIFGFSLAIISVGLVWDQRDRNFLQLICVDDFSILYIILV
LVSGLSSSVLAYKWLLIYPSNNRDEFYLLLLISSIGGILLATTNHLVILFLGMELISLPLFGLIGYSFFNKFSLEASIKY
IILSGVSSSFILFGIALIYAATGFLSFTSISQLLRLHIIASNQSIFMSTIGLGMMMVGFGFKLSLVPFHLWTPDVYQGAP
SSISLYLTTSSKIAVISVLIRLLMVFPNQYNTVFCIFLLGIACCSALFGNLMAIKQDNIKRVLAYSSIAHTGYVLIGVIA
ILRVNHPMALETIGIYLISYVLTSIGAFGIINIVSFFYAHEDTDVDSLFVYRGLFWHQPMLSVLFTIIILSLAGIPMTLG
FIGKFYLFVLGIDSKLWWFTIFIAMSSVISIFYYLRIIINLYLSPINRLNINSDFLSSWSVTPDKIIVIIVSFSILFLGL
YPKPLIYFMHLIYPPVL

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1007

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 2 (chain N)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 2 family

Homologues:

Organism=Homo sapiens, GI251831108, Length=223, Percent_Identity=27.3542600896861, Blast_Score=72, Evalue=9e-13,
Organism=Escherichia coli, GI145693160, Length=494, Percent_Identity=48.9878542510121, Blast_Score=464, Evalue=1e-132,
Organism=Escherichia coli, GI1788831, Length=308, Percent_Identity=27.5974025974026, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1788613, Length=350, Percent_Identity=26.5714285714286, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1788829, Length=347, Percent_Identity=23.6311239193084, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1788614, Length=215, Percent_Identity=25.5813953488372, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1788827, Length=267, Percent_Identity=25.0936329588015, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUON_BLOPB (Q492I8)

Other databases:

- EMBL:   CP000016
- RefSeq:   YP_277988.1
- STRING:   Q492I8
- GeneID:   3563014
- GenomeReviews:   CP000016_GR
- KEGG:   bpn:BPEN_497
- HOGENOM:   HBG747830
- OMA:   ILSISYN
- ProtClustDB:   CLSK280895
- BioCyc:   CBLO291272:BPEN_497-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_00445
- InterPro:   IPR010096
- InterPro:   IPR001750
- TIGRFAMs:   TIGR01770

Pfam domain/function: PF00361 Oxidored_q1

EC number: =1.6.99.5

Molecular weight: Translated: 55789; Mature: 55789

Theoretical pI: Translated: 8.89; Mature: 8.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xf2e068c)-; HASH(0x11bad000)-; HASH(0x11b41cec)-; HASH(0x10aebf90)-; HASH(0x1060eb08)-; HASH(0x11cc761c)-; HASH(0x1173cb54)-; HASH(0x1067ded4)-; HASH(0x11fff650)-; HASH(0xdaa565c)-; HASH(0x11fff698)-; HASH(0x11d03c0c)-; HASH(0x10a55b70)-; HASH(0x11bcee28)-;

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLITWTHIILLLPILIIGMTTVIVMLSIAYRRNLFLHTSLTIFGFSLAIISVGLVWDQRD
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHEEECCC
RNFLQLICVDDFSILYIILVLVSGLSSSVLAYKWLLIYPSNNRDEFYLLLLISSIGGILL
CCEEEEEEECCHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCCEEEEEEHHHHCCEEE
ATTNHLVILFLGMELISLPLFGLIGYSFFNKFSLEASIKYIILSGVSSSFILFGIALIYA
EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCHHHHHHHHHHHHH
ATGFLSFTSISQLLRLHIIASNQSIFMSTIGLGMMMVGFGFKLSLVPFHLWTPDVYQGAP
HHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHCCCEEEEEEEEECCCHHHCCCC
SSISLYLTTSSKIAVISVLIRLLMVFPNQYNTVFCIFLLGIACCSALFGNLMAIKQDNIK
CCEEEEEECCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCEEHCCHHHHH
RVLAYSSIAHTGYVLIGVIAILRVNHPMALETIGIYLISYVLTSIGAFGIINIVSFFYAH
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
EDTDVDSLFVYRGLFWHQPMLSVLFTIIILSLAGIPMTLGFIGKFYLFVLGIDSKLWWFT
CCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHH
IFIAMSSVISIFYYLRIIINLYLSPINRLNINSDFLSSWSVTPDKIIVIIVSFSILFLGL
HHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHC
YPKPLIYFMHLIYPPVL
CCHHHHHHHHHHCCCCH
>Mature Secondary Structure
MLITWTHIILLLPILIIGMTTVIVMLSIAYRRNLFLHTSLTIFGFSLAIISVGLVWDQRD
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHHHHHEEECCC
RNFLQLICVDDFSILYIILVLVSGLSSSVLAYKWLLIYPSNNRDEFYLLLLISSIGGILL
CCEEEEEEECCHHHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCCEEEEEEHHHHCCEEE
ATTNHLVILFLGMELISLPLFGLIGYSFFNKFSLEASIKYIILSGVSSSFILFGIALIYA
EECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCHHHHHHHHHHHHH
ATGFLSFTSISQLLRLHIIASNQSIFMSTIGLGMMMVGFGFKLSLVPFHLWTPDVYQGAP
HHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHCCCEEEEEEEEECCCHHHCCCC
SSISLYLTTSSKIAVISVLIRLLMVFPNQYNTVFCIFLLGIACCSALFGNLMAIKQDNIK
CCEEEEEECCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCEEHCCHHHHH
RVLAYSSIAHTGYVLIGVIAILRVNHPMALETIGIYLISYVLTSIGAFGIINIVSFFYAH
HHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
EDTDVDSLFVYRGLFWHQPMLSVLFTIIILSLAGIPMTLGFIGKFYLFVLGIDSKLWWFT
CCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHH
IFIAMSSVISIFYYLRIIINLYLSPINRLNINSDFLSSWSVTPDKIIVIIVSFSILFLGL
HHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCHHHHCCCCCCCHHHHHHHHHHHHHHHHC
YPKPLIYFMHLIYPPVL
CCHHHHHHHHHHCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA