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The map label for this gene is ahpC [C]

Identifier: 71892009

GI number: 71892009

Start: 264460

End: 265062

Strand: Reverse

Name: ahpC [C]

Synonym: BPEN_235

Alternate gene names: 71892009

Gene position: 265062-264460 (Counterclockwise)

Preceding gene: 71892018

Following gene: 71892006

Centisome position: 33.48

GC content: 34.49

Gene sequence:

>603_bases
ATGGTATTAGTTAGTCATTGTGCTCCAGATTTTACTTCTTCCGCAGTATTAGGAAACGGTGAAATTGTAGATAATTTTAA
TTTATTAAATTATATTAATAAAAAAGAAGCAATAGTGTTTTTTTGGCCCATGGATTTCACTTTTGTGTGTCCATCGGAAT
TGATTGCTTGCGACAAGCGTTATGTTGAGTTTCAGAAACGAAACGTAGAGGTTATTGGGGTTTCTATAGATTCAGTTTTC
GTCCACAATGCTTGGAGACAAATTCCTGTAAGTCAGGGCGGGATTGGATTGTTAAAATATGCTATGGTTTCTGATATAAA
ACGTGAAATTATTAAAAAATATGGTATTGAACACTCGAATAAAGGCGTGGCTTTACGCGCTTCTTTCTTAATTGACAAAT
CGGGAGTAATACGTCATCAAGTAGTTAATGATTTACCTTTTGGTAGAAATTTTGATGAAATGATTCGCATGGTAGATGCC
TTGAAGTTTCATGAGGTTCATGGTTTACTATGTCCCGCTCAATGGAACAAAAATAAAAAGGGACTAGAAGCATCACAGAA
AGGGGTAGTTGATTATCTTTCTGAAAATTTCTCTCAATTGTAA

Upstream 100 bases:

>100_bases
TGAAACAGTAGAATAAATATTGATCGTCAGCATCAATATTTATATATTTAATGTCGTAAAAATATTGAATATATTACAAC
AAAAATTATAAGGAATCAAT

Downstream 100 bases:

>100_bases
GTAAGTAAATATCCTTGCATTATAAGTTAGTAAAGTAATAGGTTCGGTGTTGCTTGACAAATACAGGCGTTTGATCATAA
ATCAAAATTATTTAAATCAA

Product: alkyl hydroperoxide reductase C22 protein

Products: NA

Alternate protein names: Thioredoxin reductase [H]

Number of amino acids: Translated: 200; Mature: 200

Protein sequence:

>200_residues
MVLVSHCAPDFTSSAVLGNGEIVDNFNLLNYINKKEAIVFFWPMDFTFVCPSELIACDKRYVEFQKRNVEVIGVSIDSVF
VHNAWRQIPVSQGGIGLLKYAMVSDIKREIIKKYGIEHSNKGVALRASFLIDKSGVIRHQVVNDLPFGRNFDEMIRMVDA
LKFHEVHGLLCPAQWNKNKKGLEASQKGVVDYLSENFSQL

Sequences:

>Translated_200_residues
MVLVSHCAPDFTSSAVLGNGEIVDNFNLLNYINKKEAIVFFWPMDFTFVCPSELIACDKRYVEFQKRNVEVIGVSIDSVF
VHNAWRQIPVSQGGIGLLKYAMVSDIKREIIKKYGIEHSNKGVALRASFLIDKSGVIRHQVVNDLPFGRNFDEMIRMVDA
LKFHEVHGLLCPAQWNKNKKGLEASQKGVVDYLSENFSQL
>Mature_200_residues
MVLVSHCAPDFTSSAVLGNGEIVDNFNLLNYINKKEAIVFFWPMDFTFVCPSELIACDKRYVEFQKRNVEVIGVSIDSVF
VHNAWRQIPVSQGGIGLLKYAMVSDIKREIIKKYGIEHSNKGVALRASFLIDKSGVIRHQVVNDLPFGRNFDEMIRMVDA
LKFHEVHGLLCPAQWNKNKKGLEASQKGVVDYLSENFSQL

Specific function: Directly Reduces Organic Hydroperoxides In Its Reduced Dithiol Form. [C]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI4505591, Length=193, Percent_Identity=41.4507772020725, Blast_Score=172, Evalue=2e-43,
Organism=Homo sapiens, GI32455266, Length=193, Percent_Identity=41.4507772020725, Blast_Score=172, Evalue=2e-43,
Organism=Homo sapiens, GI32455264, Length=193, Percent_Identity=41.4507772020725, Blast_Score=172, Evalue=2e-43,
Organism=Homo sapiens, GI5802974, Length=192, Percent_Identity=40.625, Blast_Score=160, Evalue=8e-40,
Organism=Homo sapiens, GI32483377, Length=188, Percent_Identity=40.9574468085106, Blast_Score=159, Evalue=2e-39,
Organism=Homo sapiens, GI32189392, Length=193, Percent_Identity=38.3419689119171, Blast_Score=158, Evalue=3e-39,
Organism=Homo sapiens, GI5453549, Length=192, Percent_Identity=38.5416666666667, Blast_Score=152, Evalue=2e-37,
Organism=Homo sapiens, GI4758638, Length=189, Percent_Identity=28.5714285714286, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI33188454, Length=84, Percent_Identity=42.8571428571429, Blast_Score=73, Evalue=2e-13,
Organism=Escherichia coli, GI1786822, Length=150, Percent_Identity=35.3333333333333, Blast_Score=105, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI193204376, Length=190, Percent_Identity=40.5263157894737, Blast_Score=150, Evalue=4e-37,
Organism=Caenorhabditis elegans, GI32565831, Length=190, Percent_Identity=40.5263157894737, Blast_Score=150, Evalue=5e-37,
Organism=Caenorhabditis elegans, GI17554494, Length=186, Percent_Identity=36.5591397849462, Blast_Score=142, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI25153706, Length=178, Percent_Identity=30.8988764044944, Blast_Score=84, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6323613, Length=190, Percent_Identity=34.2105263157895, Blast_Score=130, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6320661, Length=190, Percent_Identity=31.0526315789474, Blast_Score=117, Evalue=9e-28,
Organism=Saccharomyces cerevisiae, GI6319407, Length=176, Percent_Identity=28.9772727272727, Blast_Score=83, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24656348, Length=195, Percent_Identity=42.0512820512821, Blast_Score=166, Evalue=1e-41,
Organism=Drosophila melanogaster, GI17864676, Length=195, Percent_Identity=42.0512820512821, Blast_Score=166, Evalue=1e-41,
Organism=Drosophila melanogaster, GI17738015, Length=192, Percent_Identity=41.6666666666667, Blast_Score=161, Evalue=2e-40,
Organism=Drosophila melanogaster, GI21357347, Length=193, Percent_Identity=37.8238341968912, Blast_Score=147, Evalue=4e-36,
Organism=Drosophila melanogaster, GI17157991, Length=193, Percent_Identity=37.3056994818653, Blast_Score=145, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24641739, Length=193, Percent_Identity=37.3056994818653, Blast_Score=145, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24581278, Length=178, Percent_Identity=31.4606741573034, Blast_Score=97, Evalue=9e-21,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 22652; Mature: 22652

Theoretical pI: Translated: 7.99; Mature: 7.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLVSHCAPDFTSSAVLGNGEIVDNFNLLNYINKKEAIVFFWPMDFTFVCPSELIACDKR
CEEECCCCCCCCCCEEECCCCEEECCHHHHHCCCCCEEEEEECCCEEEECCHHHHHHHHH
YVEFQKRNVEVIGVSIDSVFVHNAWRQIPVSQGGIGLLKYAMVSDIKREIIKKYGIEHSN
HHHHHHCCEEEEEEEHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC
KGVALRASFLIDKSGVIRHQVVNDLPFGRNFDEMIRMVDALKFHEVHGLLCPAQWNKNKK
CCEEEEEEEEECCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCEECCCCCCCCCC
GLEASQKGVVDYLSENFSQL
CCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVLVSHCAPDFTSSAVLGNGEIVDNFNLLNYINKKEAIVFFWPMDFTFVCPSELIACDKR
CEEECCCCCCCCCCEEECCCCEEECCHHHHHCCCCCEEEEEECCCEEEECCHHHHHHHHH
YVEFQKRNVEVIGVSIDSVFVHNAWRQIPVSQGGIGLLKYAMVSDIKREIIKKYGIEHSN
HHHHHHCCEEEEEEEHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCC
KGVALRASFLIDKSGVIRHQVVNDLPFGRNFDEMIRMVDALKFHEVHGLLCPAQWNKNKK
CCEEEEEEEEECCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCEECCCCCCCCCC
GLEASQKGVVDYLSENFSQL
CCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12089438 [H]