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The map label for this gene is rnhA

Identifier: 71892006

GI number: 71892006

Start: 261986

End: 262441

Strand: Reverse

Name: rnhA

Synonym: BPEN_231

Alternate gene names: 71892006

Gene position: 262441-261986 (Counterclockwise)

Preceding gene: 71892009

Following gene: 71892005

Centisome position: 33.15

GC content: 32.68

Gene sequence:

>456_bases
ATGTATAAAAAAATAGAAATTTTTACGGATGGGTCATGTCTTGGTAATCCAGGTCCAGGTGGTTGTGCTGCGATATTACG
GTATAAACAACATAAGAAAGAATTTAGTATTGGGTACCGATTAACTACTAATAATCGTATGGAATTAATGGCGGCTATTA
TCGCATTAGAATCGCTTAAAAATCCCTGTCAAATCATTTTAAATACTGACAGCCAATATTTATTACACGGTATTACTCAA
TGGATTCATATATGGAAAAAACATCACTGGAAAACCTCTGAAGAAAAATTAGTAAAAAATATTGATTTATGGCAACGTCT
AGATGTAGCGATACAAATTCATAGCATTATACATTGGAATTGGTTAAAAAGCCATACTGGACATCCAGATAATGAACGAT
GCGATCAATTAGCTCGATTAGCTGCGAAATGCCCTATAAATGAAGATTTTTATTAA

Upstream 100 bases:

>100_bases
TTCAGTATCTAAAACGATTTGTCGTATAATATTAGTGCTCATAGCTTTTCATTTGTGTCACACTAGTTATTTAAATTGAA
ATGATAATATATCCTATAAT

Downstream 100 bases:

>100_bases
TGATTATTATTTGGAATCAGTATTATTACATAATTAATCATATAATAATTATAGAAATATAATTTTCATATATAAGGCTC
TTACGTATCGAAATTCTTAA

Product: ribonuclease H

Products: NA

Alternate protein names: RNase H

Number of amino acids: Translated: 151; Mature: 151

Protein sequence:

>151_residues
MYKKIEIFTDGSCLGNPGPGGCAAILRYKQHKKEFSIGYRLTTNNRMELMAAIIALESLKNPCQIILNTDSQYLLHGITQ
WIHIWKKHHWKTSEEKLVKNIDLWQRLDVAIQIHSIIHWNWLKSHTGHPDNERCDQLARLAAKCPINEDFY

Sequences:

>Translated_151_residues
MYKKIEIFTDGSCLGNPGPGGCAAILRYKQHKKEFSIGYRLTTNNRMELMAAIIALESLKNPCQIILNTDSQYLLHGITQ
WIHIWKKHHWKTSEEKLVKNIDLWQRLDVAIQIHSIIHWNWLKSHTGHPDNERCDQLARLAAKCPINEDFY
>Mature_151_residues
MYKKIEIFTDGSCLGNPGPGGCAAILRYKQHKKEFSIGYRLTTNNRMELMAAIIALESLKNPCQIILNTDSQYLLHGITQ
WIHIWKKHHWKTSEEKLVKNIDLWQRLDVAIQIHSIIHWNWLKSHTGHPDNERCDQLARLAAKCPINEDFY

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids

COG id: COG0328

COG function: function code L; Ribonuclease HI

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RNase H domain

Homologues:

Organism=Homo sapiens, GI21359816, Length=144, Percent_Identity=36.8055555555556, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1786408, Length=149, Percent_Identity=67.1140939597315, Blast_Score=215, Evalue=9e-58,
Organism=Caenorhabditis elegans, GI115532542, Length=147, Percent_Identity=33.3333333333333, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI17137476, Length=142, Percent_Identity=34.5070422535211, Blast_Score=87, Evalue=5e-18,
Organism=Drosophila melanogaster, GI45552509, Length=142, Percent_Identity=34.5070422535211, Blast_Score=87, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNH_BLOPB (Q493H7)

Other databases:

- EMBL:   CP000016
- RefSeq:   YP_277736.1
- HSSP:   P0A7Y4
- ProteinModelPortal:   Q493H7
- SMR:   Q493H7
- STRING:   Q493H7
- GeneID:   3562616
- GenomeReviews:   CP000016_GR
- KEGG:   bpn:BPEN_231
- eggNOG:   COG0328
- HOGENOM:   HBG742437
- OMA:   NGWRTAD
- ProtClustDB:   PRK00203
- BioCyc:   CBLO291272:BPEN_231-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00042
- InterPro:   IPR022892
- InterPro:   IPR012337
- InterPro:   IPR002156

Pfam domain/function: PF00075 RnaseH; SSF53098 RNaseH_fold

EC number: =3.1.26.4

Molecular weight: Translated: 17621; Mature: 17621

Theoretical pI: Translated: 8.73; Mature: 8.73

Prosite motif: PS50879 RNASE_H

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYKKIEIFTDGSCLGNPGPGGCAAILRYKQHKKEFSIGYRLTTNNRMELMAAIIALESLK
CCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHCC
NPCQIILNTDSQYLLHGITQWIHIWKKHHWKTSEEKLVKNIDLWQRLDVAIQIHSIIHWN
CCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WLKSHTGHPDNERCDQLARLAAKCPINEDFY
HHHHCCCCCCHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MYKKIEIFTDGSCLGNPGPGGCAAILRYKQHKKEFSIGYRLTTNNRMELMAAIIALESLK
CCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHHHHHCC
NPCQIILNTDSQYLLHGITQWIHIWKKHHWKTSEEKLVKNIDLWQRLDVAIQIHSIIHWN
CCEEEEECCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WLKSHTGHPDNERCDQLARLAAKCPINEDFY
HHHHCCCCCCHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA