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The map label for this gene is 68535993

Identifier: 68535993

GI number: 68535993

Start: 1093770

End: 1095449

Strand: Direct

Name: 68535993

Synonym: jk0916

Alternate gene names: NA

Gene position: 1093770-1095449 (Clockwise)

Preceding gene: 68535992

Following gene: 68535994

Centisome position: 44.42

GC content: 64.29

Gene sequence:

>1680_bases
GTGACTACTCCCACGAACCCCGATGTCATCATTGTCGGCGCCGGCCTGGCCGGCCTCGTCGCCGCCTACGAGGCGCAGAA
GTCGGGTCTGAAGGTCCTGATCCTGGACCAGGAAAACCGTAACAACCTGGGCGGACAGGCCTTCTGGTCGCTCGGTGGCC
TGTTCTATGTGGGAAGCCCCGAGCAGAAGCTGATGGGAGTCAAGGATTCCGAGGAGCTCGCTTGGCGCGACTGGGAAAAC
TCCGCGCAGTTCGACGATTCCCAGAACGATTACTGGCCGCGCCGCTGGGGCCGCGAGTACGTCCGCTTCGCAGCCACTGA
GAAGCGCGACTACCTCAAGGCTCTCGGCCTCAACGTGCTGCCCACCGTCGGCTGGGCCGAGCGCGGTTCCGGAGACGCCA
GCGGCCACGGCAATTCCGTGCCCCGCTTCCACCTGACCTGGGGCACCGGCCCCGAGGTCGTACGCGTCTTCCGCGAACCC
ATCGAGGCTGCCGAGGCGGAAGGCAAGGTCGAGTTCCGCTTCCGCCACCAGGTCGACGAGCTGATTGTAGAAAATGACGC
CGTCGTCGGCGTGCGCGGCAGCGTGCTGGAACCGAGCGATTTGGACCGCGGCGTGGCGTCATCTAGAAAGACGGTAGGGG
AGTTCGAGCTGCGCGCGCGTGCCGTCGTAGTGACCTCCGGCGGCATCGGCGGCAACCTCGACCTGGTGCGCCGCGCGTGG
CCGACCGACCAGTGGGGCCCGGTGCCGAACGACATGGTCACCGGCGTGCCCGCCCATGTGGACGGCCGCATGATCCAGAT
CTCCGAAACCGCCGGCGCGAACCTGGTGAACACCGACCGCATGTGGGCTTACACCGAGGGAATGAAGAACTGGAATTCCA
TCTGGCCTGGCCACGGCATCCGCATCATCCCGGGCCCGTCCTCGCTGTGGATTGACGCGACCGGCAAGCGCTTCCCAAGC
AACATCATTCCGGGCGGCGACACGATCGCCACCATGAAGCACCTCGGTACCACGGGCCACAGTTACTCCTGGTTCATCCT
GAACAAGACTATCGCCGACAAGGAGTTCATCTTCTCCGGCTCCGAGCAGAACCCGGATCTCACGATCAAGAAGGTCAAGA
ACCTACTTTCCAAGGTTGGCCCCGGCACCCACCCCGCCGTGAAGGCCTTTATGGACCACGGCGAGGACTGGGTGGTCGCC
GACGACCTCGGTTCCCTGGTCGAGGGCATGAACGCTATCGCCGACGACGATGCCCCCGCCCTCGACGTCCACGACCTGCG
TCGCATCATCGAGGACCGCGACTCGCAGATCGACAATAACTTCAGCAAGGACGCGCAAATCAACTACATCCGCACTGCCC
GCGGGTACCTCGGCGACAAGATTGTCCGCTGTGCCGCGCCGCACCGCCTACTCGACGAGTCGAAGGGGCCGCTTATCGCC
GTCAAGCTGCACATCCTGACCCGCAAGACCCTCGGTGGCATCGAGACCGATCTTTCCGGACGGTGCTTGCGCTCTGATGG
ATCGGTGCTGCCTGGCCTTTATGCCGCAGGCGAGGTCGCCGGTTTCGGTGGCGGCGGTATGCATGGCAAGAATGCCCTTG
AAGGCACCTTCCTCGGAGGCTGCATCCACTCCGGCAAGCGTGTTGGCGAGAACCTGAAGGCGACCATTGCTGAGCTCTAG

Upstream 100 bases:

>100_bases
TCCTCGCCCCTAAGTAGTTTTGCGATTTCCCCGCGGGGCTCGCCGGATAGTTTTAGCGTAATAATAAATATTCGCGCATA
ACCCCGAGAGGAACTCTTCC

Downstream 100 bases:

>100_bases
TCAGTGGCGCACCGCTGCATGGCGTGCCGGTGCTCATTAAGGAAGAAGTTGATGTCCGCGGGGTGCCCACGACCTACGGC
ACCAATGCCAACCCCACGCC

Product: putative FAD-binding dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 559; Mature: 558

Protein sequence:

>559_residues
MTTPTNPDVIIVGAGLAGLVAAYEAQKSGLKVLILDQENRNNLGGQAFWSLGGLFYVGSPEQKLMGVKDSEELAWRDWEN
SAQFDDSQNDYWPRRWGREYVRFAATEKRDYLKALGLNVLPTVGWAERGSGDASGHGNSVPRFHLTWGTGPEVVRVFREP
IEAAEAEGKVEFRFRHQVDELIVENDAVVGVRGSVLEPSDLDRGVASSRKTVGEFELRARAVVVTSGGIGGNLDLVRRAW
PTDQWGPVPNDMVTGVPAHVDGRMIQISETAGANLVNTDRMWAYTEGMKNWNSIWPGHGIRIIPGPSSLWIDATGKRFPS
NIIPGGDTIATMKHLGTTGHSYSWFILNKTIADKEFIFSGSEQNPDLTIKKVKNLLSKVGPGTHPAVKAFMDHGEDWVVA
DDLGSLVEGMNAIADDDAPALDVHDLRRIIEDRDSQIDNNFSKDAQINYIRTARGYLGDKIVRCAAPHRLLDESKGPLIA
VKLHILTRKTLGGIETDLSGRCLRSDGSVLPGLYAAGEVAGFGGGGMHGKNALEGTFLGGCIHSGKRVGENLKATIAEL

Sequences:

>Translated_559_residues
MTTPTNPDVIIVGAGLAGLVAAYEAQKSGLKVLILDQENRNNLGGQAFWSLGGLFYVGSPEQKLMGVKDSEELAWRDWEN
SAQFDDSQNDYWPRRWGREYVRFAATEKRDYLKALGLNVLPTVGWAERGSGDASGHGNSVPRFHLTWGTGPEVVRVFREP
IEAAEAEGKVEFRFRHQVDELIVENDAVVGVRGSVLEPSDLDRGVASSRKTVGEFELRARAVVVTSGGIGGNLDLVRRAW
PTDQWGPVPNDMVTGVPAHVDGRMIQISETAGANLVNTDRMWAYTEGMKNWNSIWPGHGIRIIPGPSSLWIDATGKRFPS
NIIPGGDTIATMKHLGTTGHSYSWFILNKTIADKEFIFSGSEQNPDLTIKKVKNLLSKVGPGTHPAVKAFMDHGEDWVVA
DDLGSLVEGMNAIADDDAPALDVHDLRRIIEDRDSQIDNNFSKDAQINYIRTARGYLGDKIVRCAAPHRLLDESKGPLIA
VKLHILTRKTLGGIETDLSGRCLRSDGSVLPGLYAAGEVAGFGGGGMHGKNALEGTFLGGCIHSGKRVGENLKATIAEL
>Mature_558_residues
TTPTNPDVIIVGAGLAGLVAAYEAQKSGLKVLILDQENRNNLGGQAFWSLGGLFYVGSPEQKLMGVKDSEELAWRDWENS
AQFDDSQNDYWPRRWGREYVRFAATEKRDYLKALGLNVLPTVGWAERGSGDASGHGNSVPRFHLTWGTGPEVVRVFREPI
EAAEAEGKVEFRFRHQVDELIVENDAVVGVRGSVLEPSDLDRGVASSRKTVGEFELRARAVVVTSGGIGGNLDLVRRAWP
TDQWGPVPNDMVTGVPAHVDGRMIQISETAGANLVNTDRMWAYTEGMKNWNSIWPGHGIRIIPGPSSLWIDATGKRFPSN
IIPGGDTIATMKHLGTTGHSYSWFILNKTIADKEFIFSGSEQNPDLTIKKVKNLLSKVGPGTHPAVKAFMDHGEDWVVAD
DLGSLVEGMNAIADDDAPALDVHDLRRIIEDRDSQIDNNFSKDAQINYIRTARGYLGDKIVRCAAPHRLLDESKGPLIAV
KLHILTRKTLGGIETDLSGRCLRSDGSVLPGLYAAGEVAGFGGGGMHGKNALEGTFLGGCIHSGKRVGENLKATIAEL

Specific function: Able to catalyze the elimination of the C-1 and C-2 hydrogen atoms of the A-ring from the polycyclic ring structure of 3-ketosteroids, but the ketosteroid dehydrogenase activity is low compared to KsdD in the cholesterol degradation process. The low activ

COG id: COG3573

COG function: function code R; Predicted oxidoreductase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent oxidoreductase 2 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 60765; Mature: 60634

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTPTNPDVIIVGAGLAGLVAAYEAQKSGLKVLILDQENRNNLGGQAFWSLGGLFYVGSP
CCCCCCCCEEEECCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHCCCEEEECCC
EQKLMGVKDSEELAWRDWENSAQFDDSQNDYWPRRWGREYVRFAATEKRDYLKALGLNVL
HHHHCCCCCCHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PTVGWAERGSGDASGHGNSVPRFHLTWGTGPEVVRVFREPIEAAEAEGKVEFRFRHQVDE
CCCCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCEEEEEHHHHHH
LIVENDAVVGVRGSVLEPSDLDRGVASSRKTVGEFELRARAVVVTSGGIGGNLDLVRRAW
HHHCCCEEEECCCCCCCCCHHHHHHHHHHHHHHCEEEEEEEEEEECCCCCCCHHHHHHCC
PTDQWGPVPNDMVTGVPAHVDGRMIQISETAGANLVNTDRMWAYTEGMKNWNSIWPGHGI
CCCCCCCCCCHHHCCCCCCCCCEEEEEECCCCCCEECCCCEEEEHHHHCCCCCCCCCCCE
RIIPGPSSLWIDATGKRFPSNIIPGGDTIATMKHLGTTGHSYSWFILNKTIADKEFIFSG
EEEECCCCEEEECCCCCCCCCCCCCCCHHHHHHHCCCCCCCEEEEEEECCCCCCEEEECC
SEQNPDLTIKKVKNLLSKVGPGTHPAVKAFMDHGEDWVVADDLGSLVEGMNAIADDDAPA
CCCCCCEEHHHHHHHHHHCCCCCCHHHHHHHHCCCCEEEHHHHHHHHHHHHHHCCCCCCC
LDVHDLRRIIEDRDSQIDNNFSKDAQINYIRTARGYLGDKIVRCAAPHRLLDESKGPLIA
CCHHHHHHHHHHHHHHHCCCCCCCCEEEEEEHHHHHHHHHHHHHCCCHHHHHCCCCCEEE
VKLHILTRKTLGGIETDLSGRCLRSDGSVLPGLYAAGEVAGFGGGGMHGKNALEGTFLGG
EEEEEEHHHHHCCCCCCCCCCEECCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCEEHH
CIHSGKRVGENLKATIAEL
HHHCCHHHCCHHHHHHHCC
>Mature Secondary Structure 
TTPTNPDVIIVGAGLAGLVAAYEAQKSGLKVLILDQENRNNLGGQAFWSLGGLFYVGSP
CCCCCCCEEEECCCHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHHHCCCEEEECCC
EQKLMGVKDSEELAWRDWENSAQFDDSQNDYWPRRWGREYVRFAATEKRDYLKALGLNVL
HHHHCCCCCCHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCC
PTVGWAERGSGDASGHGNSVPRFHLTWGTGPEVVRVFREPIEAAEAEGKVEFRFRHQVDE
CCCCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCEEEEEHHHHHH
LIVENDAVVGVRGSVLEPSDLDRGVASSRKTVGEFELRARAVVVTSGGIGGNLDLVRRAW
HHHCCCEEEECCCCCCCCCHHHHHHHHHHHHHHCEEEEEEEEEEECCCCCCCHHHHHHCC
PTDQWGPVPNDMVTGVPAHVDGRMIQISETAGANLVNTDRMWAYTEGMKNWNSIWPGHGI
CCCCCCCCCCHHHCCCCCCCCCEEEEEECCCCCCEECCCCEEEEHHHHCCCCCCCCCCCE
RIIPGPSSLWIDATGKRFPSNIIPGGDTIATMKHLGTTGHSYSWFILNKTIADKEFIFSG
EEEECCCCEEEECCCCCCCCCCCCCCCHHHHHHHCCCCCCCEEEEEEECCCCCCEEEECC
SEQNPDLTIKKVKNLLSKVGPGTHPAVKAFMDHGEDWVVADDLGSLVEGMNAIADDDAPA
CCCCCCEEHHHHHHHHHHCCCCCCHHHHHHHHCCCCEEEHHHHHHHHHHHHHHCCCCCCC
LDVHDLRRIIEDRDSQIDNNFSKDAQINYIRTARGYLGDKIVRCAAPHRLLDESKGPLIA
CCHHHHHHHHHHHHHHHCCCCCCCCEEEEEEHHHHHHHHHHHHHCCCHHHHHCCCCCEEE
VKLHILTRKTLGGIETDLSGRCLRSDGSVLPGLYAAGEVAGFGGGGMHGKNALEGTFLGG
EEEEEEHHHHHCCCCCCCCCCEECCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCEEHH
CIHSGKRVGENLKATIAEL
HHHCCHHHCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA