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The map label for this gene is murG

Identifier: 68535825

GI number: 68535825

Start: 896712

End: 897824

Strand: Direct

Name: murG

Synonym: jk0750

Alternate gene names: 68535825

Gene position: 896712-897824 (Clockwise)

Preceding gene: 68535824

Following gene: 68535826

Centisome position: 36.41

GC content: 64.6

Gene sequence:

>1113_bases
GTGAACCCGAAGCCAGAAGCCGACCGGAAGCTATCAGTCGTCGTTGCCGGCGGCGGAACGGCCGGGCACATTGAACCCGC
CATGGCCGTGGCAGAGGCAGTTCGCGCGCAGCGCCCCGATGCGCGCATCACCGCGCTGGGAACTACCCGTGGCCTGGAGA
CCACCCTGGTACCAGCCCGTGGTTTCGATCTGCAGTTGATCCCCCCGGTGCCAGTGCCGCGCAAGTTGAACAAGGACTTG
GCTACGCTGCCGCTGCGCCTGCGCAAGGCACTCAAGGAGACGAAGCGGGTGCTGCGGGAGGTGGAGGCCGATGTAGTCAT
CGGCTTCGGCGGCTATGTGTCCGCCCCGGCCTACCTAGCGGCGCGATCCCTTAAGATCCCTTTCTTCGTTCACGAAGCCA
ATGCCCGCGCGGGCGTGGCAAACAAGCTAGGCGTGAAGCTGGGCGGAACCGGCCTAGCTGCAGTCGAGGATTCCGGCTTG
GAGGCTGAGATCGTGGGTATCCCCGTGCGCGAATCTGTGCTGCAACTGGACCGCAAAGCCCTGCGTGCAGAGGCCCGCGA
GTTCTTTGGCGTGGATCCGGAGGCTCCACTGCTGCTGGTGACCGGTGGATCCCAAGGCGCACGCAGCATCAATAACGCTG
TCGTGGATGCCGCCAAGACCCTGCAGGATGCGGGTATTGGGGTGCTACACGCCTATGGCAAGAAGAACGATATTGAGCTA
CCCGCGGAGGTACAGGAGGGCAAACCTCGGTACGTGGCCGTGCCGTATATCGAGCGCATGGACCTGGCGCTTGCCGCTGC
GGATGCGATCCTGTGCCGCTCGGGCGCGATGACGGTTGCCGAGGTCTCCGCCGTGGGATTGCCCGGTATCTACGTGCCAC
TGCCACACGGCAACGGCGAGCAGGAGCTCAACGTCCGCCCGATCACCCACGCCGGTGGCGGAGTGATCATTAAGGATGCA
GAGCTCACCGGCCACCGTGTTTCCCAGGAGGTCATCCCACTGCTGCGTGACGAAACCCGCTGGCAAGCGGCTAGCCTGGC
AACCCTCGCGGCTGGCCACAGGGACGCGGCCGAGAAGATCGCCGAGAAGATCATCGCAGCAGCCGACGCTTAA

Upstream 100 bases:

>100_bases
CGATGCCACGTAGCCGCCACCGGGCGGACGAATCAAGGCAGGCAGGAGCCCGCAAGGTCCGCAGAACTATCGACAATCGA
CACAGGAGGCGCTAGCCAAA

Downstream 100 bases:

>100_bases
GCACCGTTCCCAATTATTCCCCCCTCCCTTTTAGAAAGGCATCTTCTTCCACGATGAGCGATCAGCTTCAGACCACGGAC
CTCTCCCGCGTGCACATGGT

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase

Number of amino acids: Translated: 370; Mature: 370

Protein sequence:

>370_residues
MNPKPEADRKLSVVVAGGGTAGHIEPAMAVAEAVRAQRPDARITALGTTRGLETTLVPARGFDLQLIPPVPVPRKLNKDL
ATLPLRLRKALKETKRVLREVEADVVIGFGGYVSAPAYLAARSLKIPFFVHEANARAGVANKLGVKLGGTGLAAVEDSGL
EAEIVGIPVRESVLQLDRKALRAEAREFFGVDPEAPLLLVTGGSQGARSINNAVVDAAKTLQDAGIGVLHAYGKKNDIEL
PAEVQEGKPRYVAVPYIERMDLALAAADAILCRSGAMTVAEVSAVGLPGIYVPLPHGNGEQELNVRPITHAGGGVIIKDA
ELTGHRVSQEVIPLLRDETRWQAASLATLAAGHRDAAEKIAEKIIAAADA

Sequences:

>Translated_370_residues
MNPKPEADRKLSVVVAGGGTAGHIEPAMAVAEAVRAQRPDARITALGTTRGLETTLVPARGFDLQLIPPVPVPRKLNKDL
ATLPLRLRKALKETKRVLREVEADVVIGFGGYVSAPAYLAARSLKIPFFVHEANARAGVANKLGVKLGGTGLAAVEDSGL
EAEIVGIPVRESVLQLDRKALRAEAREFFGVDPEAPLLLVTGGSQGARSINNAVVDAAKTLQDAGIGVLHAYGKKNDIEL
PAEVQEGKPRYVAVPYIERMDLALAAADAILCRSGAMTVAEVSAVGLPGIYVPLPHGNGEQELNVRPITHAGGGVIIKDA
ELTGHRVSQEVIPLLRDETRWQAASLATLAAGHRDAAEKIAEKIIAAADA
>Mature_370_residues
MNPKPEADRKLSVVVAGGGTAGHIEPAMAVAEAVRAQRPDARITALGTTRGLETTLVPARGFDLQLIPPVPVPRKLNKDL
ATLPLRLRKALKETKRVLREVEADVVIGFGGYVSAPAYLAARSLKIPFFVHEANARAGVANKLGVKLGGTGLAAVEDSGL
EAEIVGIPVRESVLQLDRKALRAEAREFFGVDPEAPLLLVTGGSQGARSINNAVVDAAKTLQDAGIGVLHAYGKKNDIEL
PAEVQEGKPRYVAVPYIERMDLALAAADAILCRSGAMTVAEVSAVGLPGIYVPLPHGNGEQELNVRPITHAGGGVIIKDA
ELTGHRVSQEVIPLLRDETRWQAASLATLAAGHRDAAEKIAEKIIAAADA

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily

Homologues:

Organism=Escherichia coli, GI1786278, Length=359, Percent_Identity=35.3760445682451, Blast_Score=189, Evalue=3e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MURG_CORJK (Q4JW95)

Other databases:

- EMBL:   CR931997
- RefSeq:   YP_250530.1
- ProteinModelPortal:   Q4JW95
- SMR:   Q4JW95
- STRING:   Q4JW95
- GeneID:   3432777
- GenomeReviews:   CR931997_GR
- KEGG:   cjk:jk0750
- NMPDR:   fig|306537.3.peg.1609
- eggNOG:   COG0707
- HOGENOM:   HBG617076
- OMA:   PHGNGEQ
- ProtClustDB:   PRK00726
- BioCyc:   CJEI306537:JK0750-MONOMER
- HAMAP:   MF_00033
- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235
- TIGRFAMs:   TIGR01133

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28

EC number: =2.4.1.227

Molecular weight: Translated: 38890; Mature: 38890

Theoretical pI: Translated: 7.79; Mature: 7.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNPKPEADRKLSVVVAGGGTAGHIEPAMAVAEAVRAQRPDARITALGTTRGLETTLVPAR
CCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEECC
GFDLQLIPPVPVPRKLNKDLATLPLRLRKALKETKRVLREVEADVVIGFGGYVSAPAYLA
CCCEEEECCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHCCCHHHH
ARSLKIPFFVHEANARAGVANKLGVKLGGTGLAAVEDSGLEAEIVGIPVRESVLQLDRKA
HHCCCCEEEEEECCCCCCCCHHCCEEECCCEEEEEECCCCEEEEEECCHHHHHHHHHHHH
LRAEAREFFGVDPEAPLLLVTGGSQGARSINNAVVDAAKTLQDAGIGVLHAYGKKNDIEL
HHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCC
PAEVQEGKPRYVAVPYIERMDLALAAADAILCRSGAMTVAEVSAVGLPGIYVPLPHGNGE
CCHHHCCCCCEEECCCHHHHHHHHHHHHHHHHCCCCCEEEHHHHCCCCEEEEECCCCCCC
QELNVRPITHAGGGVIIKDAELTGHRVSQEVIPLLRDETRWQAASLATLAAGHRDAAEKI
CCEEEEEEEECCCCEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHH
AEKIIAAADA
HHHHHHHCCC
>Mature Secondary Structure
MNPKPEADRKLSVVVAGGGTAGHIEPAMAVAEAVRAQRPDARITALGTTRGLETTLVPAR
CCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEECC
GFDLQLIPPVPVPRKLNKDLATLPLRLRKALKETKRVLREVEADVVIGFGGYVSAPAYLA
CCCEEEECCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHCCCHHHH
ARSLKIPFFVHEANARAGVANKLGVKLGGTGLAAVEDSGLEAEIVGIPVRESVLQLDRKA
HHCCCCEEEEEECCCCCCCCHHCCEEECCCEEEEEECCCCEEEEEECCHHHHHHHHHHHH
LRAEAREFFGVDPEAPLLLVTGGSQGARSINNAVVDAAKTLQDAGIGVLHAYGKKNDIEL
HHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCC
PAEVQEGKPRYVAVPYIERMDLALAAADAILCRSGAMTVAEVSAVGLPGIYVPLPHGNGE
CCHHHCCCCCEEECCCHHHHHHHHHHHHHHHHCCCCCEEEHHHHCCCCEEEEECCCCCCC
QELNVRPITHAGGGVIIKDAELTGHRVSQEVIPLLRDETRWQAASLATLAAGHRDAAEKI
CCEEEEEEEECCCCEEEECCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHH
AEKIIAAADA
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA