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The map label for this gene is ftsW [C]

Identifier: 68535824

GI number: 68535824

Start: 894967

End: 896706

Strand: Direct

Name: ftsW [C]

Synonym: jk0749

Alternate gene names: 68535824

Gene position: 894967-896706 (Clockwise)

Preceding gene: 68535823

Following gene: 68535825

Centisome position: 36.34

GC content: 62.76

Gene sequence:

>1740_bases
ATGTCCACTCCGACGCCCCATTCGAAGCGCCGGCGCATCCCCGGCACCGGGGAGGCCAGCCGCCACGGCAACCGCGCCGA
CCACTCTGACCGTGCCGACGGTCCGGGTGCTGCAGACGGTGCCAACGGTCCCGGCGCTGCAGATCGTTCTTCGCGGGAGC
GAAACCCCTCTAGCCAGGAATCCGGTGCTGAGCGCGGCCTGGCCTCCCTGCAGCGCAAGTTGGCCGCACAGCTTGCCACC
CCGCAGCTGAACTACAAGGTGTTGATGGTCGTCACGGCGTGTCTGACCATTCTGGGGCTCGTCATGGTGCTGTCGTCGTC
GATGGTGACTTCCTACGCCAGCGGCGCGAGTGTCTTTGGTGAGTTTATTAAGCAGGCCGTGGTCGTGTTCCTCGGACTGG
TGGCTATGTGGGTGGCGCTACGGATGCGCCCGGAGACGATCCGCAAATATTCCCCGTGGCTGTTGGTAGTTGCGGTCGCG
ATGTTGATCGCGGTGCTTATTCCCGGAGTTGGCATCGGCGGTGAAGAGGTCGGTTCTAACTCGTGGATCCGTATTGGCCC
CATTGGCGTGCAGCCTTCCGAGGTGGCGAAGCTAGCGCTGGCGGTGTGGGGCGCAGCGACCGTCTCTTACCGAGCACGCG
CCACGCAGCGCCTCAACACCGCCCTGGGGGCCTTCTTGGCCGTGAGTTTTGCGATTCTGATGCTGGTGTTGCTGCAGAAG
GATCTCGGCATGATGTTCTCCGTAGGCATCGTGGTAGCCGCGCTTATCTTCTTCGCCGGCGTGAGCCGTCAGGTGATCAC
CTGGGTACTGGGAATCGTCGCGGTGCTGGGCGTGTTTGCGATTACCCGTCAGAGTTTCCGCGGCGCGCGTATTACGACGT
GGAAGGACGCTCTGACCCTGAACTTCGGTGATTCGACGACCCAAGGCTCGTCCTATCAGTCCCACCAGGGCATCTTGTCT
CTGTCCGACGGAGGGTTTTTCGGCGCCGGGTTGGGGCAGTCTCGTGCTAAGTGGTTCTATCTGCCAGAAGCGAAGAACGA
TTTCATTTTCGCCATTGTGGGTGAGGAGCTGGGGCTTCTTGGTGCATTCTTCGTTGTGTTCCTGTTTGGAATGCTGGCCT
GGTTTGGCATTCGCACCGCCCTGGCGCAAAAGGATCCTTTCCTGCGGCTGCTGGCGGCAACGCTGACCATCGGTATTTCC
GTGCAAGCGTTTTTCAACATGGCCTACGTTGTGGGCCTGCTGCCGGTGACAGGCATCCAGCTGCCGTTGATCTCCGCCGG
TGGTTCATCGGCGATCATCACCCTTCTTTCCATGGGGCTGCTGTGCAACTGTGCCCGCAACGAGCCGGAGACGATTTCTT
CCATGCAGCACGAAGGCCGCCCGCTCATCGATCGCATTCTCATGCTGCCGGAGCCTCAGGGGTACAAGGCCGGCGAGCAG
CGCCGTAACGAGCGCCGCGAGACCTCCTACAGCTACGGCGAGCCGGTCACCCGGCAGCGAGCGAGTGCCGGCCGGGGAAG
CCAAGATGTTCGCCGCGAACGCGACCGGGTGGAGCAGTCCATCCGTCGCGTCGGCGGCGAGTCGCGCCTGCGTGGCTACG
ATGGAGTCCGAAGGCAGGATCTGCCACCCACTGCGACCCCGAAACCGATGCCACGTAGCCGCCACCGGGCGGACGAATCA
AGGCAGGCAGGAGCCCGCAAGGTCCGCAGAACTATCGACAATCGACACAGGAGGCGCTAG

Upstream 100 bases:

>100_bases
CAGGCATGAGCCAGCGTGGCGACCTGTTCGCCCAGTATGCGGTGGCATATGCTGGGGCCGATAGAGCCGATGAACGCACT
CAGGAAAGGGGATAGGCGCG

Downstream 100 bases:

>100_bases
CCAAAGTGAACCCGAAGCCAGAAGCCGACCGGAAGCTATCAGTCGTCGTTGCCGGCGGCGGAACGGCCGGGCACATTGAA
CCCGCCATGGCCGTGGCAGA

Product: cell division protein FtsW

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 579; Mature: 578

Protein sequence:

>579_residues
MSTPTPHSKRRRIPGTGEASRHGNRADHSDRADGPGAADGANGPGAADRSSRERNPSSQESGAERGLASLQRKLAAQLAT
PQLNYKVLMVVTACLTILGLVMVLSSSMVTSYASGASVFGEFIKQAVVVFLGLVAMWVALRMRPETIRKYSPWLLVVAVA
MLIAVLIPGVGIGGEEVGSNSWIRIGPIGVQPSEVAKLALAVWGAATVSYRARATQRLNTALGAFLAVSFAILMLVLLQK
DLGMMFSVGIVVAALIFFAGVSRQVITWVLGIVAVLGVFAITRQSFRGARITTWKDALTLNFGDSTTQGSSYQSHQGILS
LSDGGFFGAGLGQSRAKWFYLPEAKNDFIFAIVGEELGLLGAFFVVFLFGMLAWFGIRTALAQKDPFLRLLAATLTIGIS
VQAFFNMAYVVGLLPVTGIQLPLISAGGSSAIITLLSMGLLCNCARNEPETISSMQHEGRPLIDRILMLPEPQGYKAGEQ
RRNERRETSYSYGEPVTRQRASAGRGSQDVRRERDRVEQSIRRVGGESRLRGYDGVRRQDLPPTATPKPMPRSRHRADES
RQAGARKVRRTIDNRHRRR

Sequences:

>Translated_579_residues
MSTPTPHSKRRRIPGTGEASRHGNRADHSDRADGPGAADGANGPGAADRSSRERNPSSQESGAERGLASLQRKLAAQLAT
PQLNYKVLMVVTACLTILGLVMVLSSSMVTSYASGASVFGEFIKQAVVVFLGLVAMWVALRMRPETIRKYSPWLLVVAVA
MLIAVLIPGVGIGGEEVGSNSWIRIGPIGVQPSEVAKLALAVWGAATVSYRARATQRLNTALGAFLAVSFAILMLVLLQK
DLGMMFSVGIVVAALIFFAGVSRQVITWVLGIVAVLGVFAITRQSFRGARITTWKDALTLNFGDSTTQGSSYQSHQGILS
LSDGGFFGAGLGQSRAKWFYLPEAKNDFIFAIVGEELGLLGAFFVVFLFGMLAWFGIRTALAQKDPFLRLLAATLTIGIS
VQAFFNMAYVVGLLPVTGIQLPLISAGGSSAIITLLSMGLLCNCARNEPETISSMQHEGRPLIDRILMLPEPQGYKAGEQ
RRNERRETSYSYGEPVTRQRASAGRGSQDVRRERDRVEQSIRRVGGESRLRGYDGVRRQDLPPTATPKPMPRSRHRADES
RQAGARKVRRTIDNRHRRR
>Mature_578_residues
STPTPHSKRRRIPGTGEASRHGNRADHSDRADGPGAADGANGPGAADRSSRERNPSSQESGAERGLASLQRKLAAQLATP
QLNYKVLMVVTACLTILGLVMVLSSSMVTSYASGASVFGEFIKQAVVVFLGLVAMWVALRMRPETIRKYSPWLLVVAVAM
LIAVLIPGVGIGGEEVGSNSWIRIGPIGVQPSEVAKLALAVWGAATVSYRARATQRLNTALGAFLAVSFAILMLVLLQKD
LGMMFSVGIVVAALIFFAGVSRQVITWVLGIVAVLGVFAITRQSFRGARITTWKDALTLNFGDSTTQGSSYQSHQGILSL
SDGGFFGAGLGQSRAKWFYLPEAKNDFIFAIVGEELGLLGAFFVVFLFGMLAWFGIRTALAQKDPFLRLLAATLTIGISV
QAFFNMAYVVGLLPVTGIQLPLISAGGSSAIITLLSMGLLCNCARNEPETISSMQHEGRPLIDRILMLPEPQGYKAGEQR
RNERRETSYSYGEPVTRQRASAGRGSQDVRRERDRVEQSIRRVGGESRLRGYDGVRRQDLPPTATPKPMPRSRHRADESR
QAGARKVRRTIDNRHRRR

Specific function: This Is A Septum-Peptidoglycan Biosynthetic Protein, Involved In Cell Wall Formation. Plays A Role In The Stabilization Of The Ftsz Ring During Cell Division. [C]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=360, Percent_Identity=33.3333333333333, Blast_Score=134, Evalue=2e-32,
Organism=Escherichia coli, GI1786853, Length=347, Percent_Identity=28.5302593659942, Blast_Score=102, Evalue=7e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR013437 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 62783; Mature: 62651

Theoretical pI: Translated: 11.28; Mature: 11.28

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTPTPHSKRRRIPGTGEASRHGNRADHSDRADGPGAADGANGPGAADRSSRERNPSSQE
CCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHH
SGAERGLASLQRKLAAQLATPQLNYKVLMVVTACLTILGLVMVLSSSMVTSYASGASVFG
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHH
EFIKQAVVVFLGLVAMWVALRMRPETIRKYSPWLLVVAVAMLIAVLIPGVGIGGEEVGSN
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCHHCCCC
SWIRIGPIGVQPSEVAKLALAVWGAATVSYRARATQRLNTALGAFLAVSFAILMLVLLQK
CCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLGMMFSVGIVVAALIFFAGVSRQVITWVLGIVAVLGVFAITRQSFRGARITTWKDALTL
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCEEEE
NFGDSTTQGSSYQSHQGILSLSDGGFFGAGLGQSRAKWFYLPEAKNDFIFAIVGEELGLL
ECCCCCCCCCCCCCCCCCEEECCCCCEECCCCCCCCEEEECCCCCCCEEEEECCCHHHHH
GAFFVVFLFGMLAWFGIRTALAQKDPFLRLLAATLTIGISVQAFFNMAYVVGLLPVTGIQ
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
LPLISAGGSSAIITLLSMGLLCNCARNEPETISSMQHEGRPLIDRILMLPEPQGYKAGEQ
EEEEECCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHCCCCCCCCCHHH
RRNERRETSYSYGEPVTRQRASAGRGSQDVRRERDRVEQSIRRVGGESRLRGYDGVRRQD
HHHHHHHCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCC
LPPTATPKPMPRSRHRADESRQAGARKVRRTIDNRHRRR
CCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
STPTPHSKRRRIPGTGEASRHGNRADHSDRADGPGAADGANGPGAADRSSRERNPSSQE
CCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHH
SGAERGLASLQRKLAAQLATPQLNYKVLMVVTACLTILGLVMVLSSSMVTSYASGASVFG
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHH
EFIKQAVVVFLGLVAMWVALRMRPETIRKYSPWLLVVAVAMLIAVLIPGVGIGGEEVGSN
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCHHCCCC
SWIRIGPIGVQPSEVAKLALAVWGAATVSYRARATQRLNTALGAFLAVSFAILMLVLLQK
CCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DLGMMFSVGIVVAALIFFAGVSRQVITWVLGIVAVLGVFAITRQSFRGARITTWKDALTL
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCEEEE
NFGDSTTQGSSYQSHQGILSLSDGGFFGAGLGQSRAKWFYLPEAKNDFIFAIVGEELGLL
ECCCCCCCCCCCCCCCCCEEECCCCCEECCCCCCCCEEEECCCCCCCEEEEECCCHHHHH
GAFFVVFLFGMLAWFGIRTALAQKDPFLRLLAATLTIGISVQAFFNMAYVVGLLPVTGIQ
HHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
LPLISAGGSSAIITLLSMGLLCNCARNEPETISSMQHEGRPLIDRILMLPEPQGYKAGEQ
EEEEECCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHCCCCCCCCCHHH
RRNERRETSYSYGEPVTRQRASAGRGSQDVRRERDRVEQSIRRVGGESRLRGYDGVRRQD
HHHHHHHCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCC
LPPTATPKPMPRSRHRADESRQAGARKVRRTIDNRHRRR
CCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]