Click here to switch to the map view.

The map label for this gene is yybE [H]

Identifier: 66766845

GI number: 66766845

Start: 595057

End: 595959

Strand: Reverse

Name: yybE [H]

Synonym: XC_0506

Alternate gene names: 66766845

Gene position: 595959-595057 (Counterclockwise)

Preceding gene: 66766847

Following gene: 66766844

Centisome position: 11.57

GC content: 72.31

Gene sequence:

>903_bases
ATGTTGACCCTGCGCCAGCTGGAGTTCGCCGTGGCGGTGGCCGACGAAGGCGGCTTCACTGCGGCCGCGCGCCGCTGCAA
CACCGTGCAATCTGCACTCAGCCACCAGGTCGCCAAGATCGAGGAGCTGCTGGGCGCGCGCCTGTTCGAACGCGGCACCC
GCCAGGTACGCCCCACCGCCGCCGGCGAGGTGTTCCTGCACAACGCGCGGCAGACGCTGCGCGCGGCCGAGCGCCTGCAT
GAAGAAATGGCCCAGGCGCTGGGCACCGTGCGCGGCCGGCTCACGCTGGGGCAGATCTCCTCGCTCACCACGGTGCAGGT
GCCGGCGCTGCTGCACCGCTTCCGCAGCGCGCATGCGCACGTGGATGTGCACCTGCGCACGGCCATGAGCGATGCCCTGC
TGCACGACCTGCGCGAAGGCCGGCTGGATCTGGCCCTGGTCGGCGTCGGCCCGCAGGTGGTGGTGCCGGAGCAGCGCCTG
CTGCTGCACGAAGAAGCACTGGCGCTGATCGTCGCGCCCGGCCACCGCTTCGCCAGCCGCAAGCGCGTGGCATTGGCCGA
GCTGGACGACGAGCCGATGGCCGGGCTGATTCCCGGCGCCGGCGTGCGCGGCATCATCGACGCGGCCTTCGACCAGGCCG
GCCTGCACCAGCGCCTGCAATACGAAGTCACCCATGCCGATCTGGTACGCGAGCTGGTCGCCGCCGGGCTGGGCGTGGGC
ATCGTGCCGCAGACCATGGCCGGCGCCATGCGTGGCGTGGTGGCGCTGGCGCTGAAGGAGCACTTCCGCTTCCTCACCTA
TGCGGTCTGGCGGCCGGACCCGACCCCGGCCACGCGCGCCTTCATCACCCTGCTGCGCGCGCAGGTGGAGCAGCAGCGCC
CGGCGCGACGCCCGGTGCGCTGA

Upstream 100 bases:

>100_bases
GGCAGCAACCTGTGTGGAGTGGATGGGGCGCAGTGTGGTCGGCACAGACCCATCTTTCCAATGTATTGTTTTCACTGTTC
CCATCTTGTTCCGAGATCGC

Downstream 100 bases:

>100_bases
GCCGCAGCGGGCGCTCCCAGCCCGGCGCTGAAGCCTGCTAGGCTGCGCGCGTCGCGAAGGAGTCCGCATGTCCGGTCACA
GTCAGTTCGCCCTGCTCAGG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 300; Mature: 300

Protein sequence:

>300_residues
MLTLRQLEFAVAVADEGGFTAAARRCNTVQSALSHQVAKIEELLGARLFERGTRQVRPTAAGEVFLHNARQTLRAAERLH
EEMAQALGTVRGRLTLGQISSLTTVQVPALLHRFRSAHAHVDVHLRTAMSDALLHDLREGRLDLALVGVGPQVVVPEQRL
LLHEEALALIVAPGHRFASRKRVALAELDDEPMAGLIPGAGVRGIIDAAFDQAGLHQRLQYEVTHADLVRELVAAGLGVG
IVPQTMAGAMRGVVALALKEHFRFLTYAVWRPDPTPATRAFITLLRAQVEQQRPARRPVR

Sequences:

>Translated_300_residues
MLTLRQLEFAVAVADEGGFTAAARRCNTVQSALSHQVAKIEELLGARLFERGTRQVRPTAAGEVFLHNARQTLRAAERLH
EEMAQALGTVRGRLTLGQISSLTTVQVPALLHRFRSAHAHVDVHLRTAMSDALLHDLREGRLDLALVGVGPQVVVPEQRL
LLHEEALALIVAPGHRFASRKRVALAELDDEPMAGLIPGAGVRGIIDAAFDQAGLHQRLQYEVTHADLVRELVAAGLGVG
IVPQTMAGAMRGVVALALKEHFRFLTYAVWRPDPTPATRAFITLLRAQVEQQRPARRPVR
>Mature_300_residues
MLTLRQLEFAVAVADEGGFTAAARRCNTVQSALSHQVAKIEELLGARLFERGTRQVRPTAAGEVFLHNARQTLRAAERLH
EEMAQALGTVRGRLTLGQISSLTTVQVPALLHRFRSAHAHVDVHLRTAMSDALLHDLREGRLDLALVGVGPQVVVPEQRL
LLHEEALALIVAPGHRFASRKRVALAELDDEPMAGLIPGAGVRGIIDAAFDQAGLHQRLQYEVTHADLVRELVAAGLGVG
IVPQTMAGAMRGVVALALKEHFRFLTYAVWRPDPTPATRAFITLLRAQVEQQRPARRPVR

Specific function: Hydrogen Peroxide Sensor. Activates The Expression Of A Regulon Of Hydrogen Peroxide-Inducible Genes Such As Katg, Gor, Ahpc, Ahpf, Oxys (A Regulatory RNA), Dps, Fur And Grxa. Oxyr Expression Is Negatively Autoregulated By Binding To A 43 Bp Region Upstre

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790399, Length=279, Percent_Identity=29.3906810035842, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1787879, Length=307, Percent_Identity=34.2019543973941, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI157672245, Length=258, Percent_Identity=31.0077519379845, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1788887, Length=297, Percent_Identity=28.956228956229, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1787806, Length=289, Percent_Identity=27.3356401384083, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1787530, Length=243, Percent_Identity=24.6913580246914, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI2367136, Length=285, Percent_Identity=26.6666666666667, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1787601, Length=177, Percent_Identity=30.5084745762712, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI145693105, Length=245, Percent_Identity=26.1224489795918, Blast_Score=75, Evalue=7e-15,
Organism=Escherichia coli, GI1788748, Length=248, Percent_Identity=25.4032258064516, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI87081904, Length=253, Percent_Identity=28.0632411067194, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI1788297, Length=264, Percent_Identity=25.3787878787879, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1788626, Length=247, Percent_Identity=28.7449392712551, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1789204, Length=242, Percent_Identity=25.6198347107438, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1790262, Length=296, Percent_Identity=27.3648648648649, Blast_Score=68, Evalue=8e-13,
Organism=Escherichia coli, GI1790208, Length=248, Percent_Identity=27.0161290322581, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1787949, Length=146, Percent_Identity=29.4520547945205, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32805; Mature: 32805

Theoretical pI: Translated: 10.85; Mature: 10.85

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTLRQLEFAVAVADEGGFTAAARRCNTVQSALSHQVAKIEELLGARLFERGTRQVRPTA
CCCHHHHHEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
AGEVFLHNARQTLRAAERLHEEMAQALGTVRGRLTLGQISSLTTVQVPALLHRFRSAHAH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEHHHHCCCHHHHHHHHHHHHHHHCCE
VDVHLRTAMSDALLHDLREGRLDLALVGVGPQVVVPEQRLLLHEEALALIVAPGHRFASR
EEEHHHHHHHHHHHHHHHCCCEEEEEEECCCEEECCHHHHHHHHHCEEEEECCCCHHHHC
KRVALAELDDEPMAGLIPGAGVRGIIDAAFDQAGLHQRLQYEVTHADLVRELVAAGLGVG
CCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
IVPQTMAGAMRGVVALALKEHFRFLTYAVWRPDPTPATRAFITLLRAQVEQQRPARRPVR
CCHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MLTLRQLEFAVAVADEGGFTAAARRCNTVQSALSHQVAKIEELLGARLFERGTRQVRPTA
CCCHHHHHEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
AGEVFLHNARQTLRAAERLHEEMAQALGTVRGRLTLGQISSLTTVQVPALLHRFRSAHAH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEHHHHCCCHHHHHHHHHHHHHHHCCE
VDVHLRTAMSDALLHDLREGRLDLALVGVGPQVVVPEQRLLLHEEALALIVAPGHRFASR
EEEHHHHHHHHHHHHHHHCCCEEEEEEECCCEEECCHHHHHHHHHCEEEEECCCCHHHHC
KRVALAELDDEPMAGLIPGAGVRGIIDAAFDQAGLHQRLQYEVTHADLVRELVAAGLGVG
CCHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
IVPQTMAGAMRGVVALALKEHFRFLTYAVWRPDPTPATRAFITLLRAQVEQQRPARRPVR
CCHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]