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The map label for this gene is alsR [H]

Identifier: 66045949

GI number: 66045949

Start: 3295137

End: 3296036

Strand: Reverse

Name: alsR [H]

Synonym: Psyr_2713

Alternate gene names: 66045949

Gene position: 3296036-3295137 (Counterclockwise)

Preceding gene: 66045950

Following gene: 66045948

Centisome position: 54.09

GC content: 60.0

Gene sequence:

>900_bases
ATGTTCGAGCTTTCCCAACTGCGTTGCTTCACCACGGTGGCCACAGAGCTGAATTTTCGCCGTGCCGCCGAACGGCTAAA
CATGACGCAGCCGCCGTTGAGCCGGCAGATTCAGATACTGGAGCACAATCTGGGCGTCGAGCTGTTCACGCGCAGCACCC
GCAGTGTGGCCCTGACTGCCGCGGGCAGGGCTTTTTTCATCGAAGCCCAGACCTTGCTGGAGCGCGCGCAGCAGGCGGCC
ATTTCTGCGCGGCGCTTTGCCGAAGGTGACATTGGTTCGGTGACCATCAGTTTTGTCGGCAGCGCGGTGTATGAGTTTCT
GCCCAGGGTGATCGCCGAGGCGCGCCTCAAGCAGCCGCAGGTGAAGATTTCCCTGACCGAAATGAATACCTATCAGCAGC
ACGAAGCACTCAGGGCGCGGCGTATTGACCTGGGCATCGTGCGGGCGCCGTTGTTTCAGCCGGGTTACGAGAGCGAATGC
CTGGTACGCGAGCCGTTCGTGCTGGCCGTGCCGAGCAATCATCGCCTGGCGCATGCCGATTCGGTGGCGGTGGCCGATCT
GGATGGCGCACCGTTCCTGATGTATTCGCATTCGGCGTATCCACCGTTCAACGAACTGCTGACCGGTATGTTTCGCTCCG
CACGAGTTGCACCGGAGTATGTCCAATGGCTTGGATCGTCACTGACTATTCTGGCGTTGGTCAACGCCGGAATGGGCCTG
GCTTTGGTGCCGCGTTGTGCAACCAATGTGGTGTTCAAGGATGTCGTGTTTCGTGACATTGACCTGGGCGAAGGCGTGCA
GAGCGAGTTGCACCTGGTCTGGCGTACCGACAATGACAATCCGGCGTGCCGGATGCTGCTGCAAGCCATTCGGGCGGCCG
TCAGGGCAGATGAAAATTGA

Upstream 100 bases:

>100_bases
ATGGGCGTCTTTCCCTTTGCTTTGTCAAACGGCGCACTGGGTTGCTCGAGCAGTTACTGTACTCTGTGTCAGTGACTTGA
TTGATACCGGGAGTGGATCA

Downstream 100 bases:

>100_bases
AGCGAAAAACCTTGCAACGTAGTGGCATCAACTATCATTCATTCAGTCGATAGTCATCATCAAGCAAGGCAAGTTCTGTT
TTTCCGGCAAAGGAGGAGGA

Product: regulatory protein, LysR:LysR, substrate-binding

Products: NA

Alternate protein names: Als operon regulatory protein [H]

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MFELSQLRCFTTVATELNFRRAAERLNMTQPPLSRQIQILEHNLGVELFTRSTRSVALTAAGRAFFIEAQTLLERAQQAA
ISARRFAEGDIGSVTISFVGSAVYEFLPRVIAEARLKQPQVKISLTEMNTYQQHEALRARRIDLGIVRAPLFQPGYESEC
LVREPFVLAVPSNHRLAHADSVAVADLDGAPFLMYSHSAYPPFNELLTGMFRSARVAPEYVQWLGSSLTILALVNAGMGL
ALVPRCATNVVFKDVVFRDIDLGEGVQSELHLVWRTDNDNPACRMLLQAIRAAVRADEN

Sequences:

>Translated_299_residues
MFELSQLRCFTTVATELNFRRAAERLNMTQPPLSRQIQILEHNLGVELFTRSTRSVALTAAGRAFFIEAQTLLERAQQAA
ISARRFAEGDIGSVTISFVGSAVYEFLPRVIAEARLKQPQVKISLTEMNTYQQHEALRARRIDLGIVRAPLFQPGYESEC
LVREPFVLAVPSNHRLAHADSVAVADLDGAPFLMYSHSAYPPFNELLTGMFRSARVAPEYVQWLGSSLTILALVNAGMGL
ALVPRCATNVVFKDVVFRDIDLGEGVQSELHLVWRTDNDNPACRMLLQAIRAAVRADEN
>Mature_299_residues
MFELSQLRCFTTVATELNFRRAAERLNMTQPPLSRQIQILEHNLGVELFTRSTRSVALTAAGRAFFIEAQTLLERAQQAA
ISARRFAEGDIGSVTISFVGSAVYEFLPRVIAEARLKQPQVKISLTEMNTYQQHEALRARRIDLGIVRAPLFQPGYESEC
LVREPFVLAVPSNHRLAHADSVAVADLDGAPFLMYSHSAYPPFNELLTGMFRSARVAPEYVQWLGSSLTILALVNAGMGL
ALVPRCATNVVFKDVVFRDIDLGEGVQSELHLVWRTDNDNPACRMLLQAIRAAVRADEN

Specific function: Regulates the expression of the alsSD operon for acetoin biosynthesis [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788887, Length=287, Percent_Identity=38.3275261324042, Blast_Score=178, Evalue=4e-46,
Organism=Escherichia coli, GI1787879, Length=297, Percent_Identity=35.016835016835, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI2367136, Length=292, Percent_Identity=31.1643835616438, Blast_Score=128, Evalue=5e-31,
Organism=Escherichia coli, GI145693105, Length=248, Percent_Identity=31.8548387096774, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI1788748, Length=248, Percent_Identity=28.6290322580645, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1790399, Length=246, Percent_Identity=28.4552845528455, Blast_Score=85, Evalue=7e-18,
Organism=Escherichia coli, GI157672245, Length=187, Percent_Identity=31.5508021390374, Blast_Score=84, Evalue=9e-18,
Organism=Escherichia coli, GI1787601, Length=223, Percent_Identity=30.9417040358744, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788297, Length=243, Percent_Identity=24.6913580246914, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1790208, Length=287, Percent_Identity=27.1777003484321, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI87081904, Length=295, Percent_Identity=24.406779661017, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1789204, Length=259, Percent_Identity=25.8687258687259, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1787806, Length=247, Percent_Identity=23.0769230769231, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788481, Length=251, Percent_Identity=25.8964143426295, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1787530, Length=257, Percent_Identity=25.6809338521401, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1789173, Length=170, Percent_Identity=31.1764705882353, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1786713, Length=298, Percent_Identity=26.8456375838926, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1789639, Length=244, Percent_Identity=26.2295081967213, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33288; Mature: 33288

Theoretical pI: Translated: 7.12; Mature: 7.12

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFELSQLRCFTTVATELNFRRAAERLNMTQPPLSRQIQILEHNLGVELFTRSTRSVALTA
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCEEEEECCCCEEEEEE
AGRAFFIEAQTLLERAQQAAISARRFAEGDIGSVTISFVGSAVYEFLPRVIAEARLKQPQ
CCCEEEEEHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCC
VKISLTEMNTYQQHEALRARRIDLGIVRAPLFQPGYESECLVREPFVLAVPSNHRLAHAD
EEEEEECCHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCEEECCEEEEECCCCCEECCC
SVAVADLDGAPFLMYSHSAYPPFNELLTGMFRSARVAPEYVQWLGSSLTILALVNAGMGL
CEEEEECCCCCEEEECCCCCCCHHHHHHHHHHHCCCCHHHHHHHCCCCEEEHHHHCCCCE
ALVPRCATNVVFKDVVFRDIDLGEGVQSELHLVWRTDNDNPACRMLLQAIRAAVRADEN
EEHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MFELSQLRCFTTVATELNFRRAAERLNMTQPPLSRQIQILEHNLGVELFTRSTRSVALTA
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCEEEEECCCCEEEEEE
AGRAFFIEAQTLLERAQQAAISARRFAEGDIGSVTISFVGSAVYEFLPRVIAEARLKQPQ
CCCEEEEEHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCC
VKISLTEMNTYQQHEALRARRIDLGIVRAPLFQPGYESECLVREPFVLAVPSNHRLAHAD
EEEEEECCHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCCEEECCEEEEECCCCCEECCC
SVAVADLDGAPFLMYSHSAYPPFNELLTGMFRSARVAPEYVQWLGSSLTILALVNAGMGL
CEEEEECCCCCEEEECCCCCCCHHHHHHHHHHHCCCCHHHHHHHCCCCEEEHHHHCCCCE
ALVPRCATNVVFKDVVFRDIDLGEGVQSELHLVWRTDNDNPACRMLLQAIRAAVRADEN
EEHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7685336; 9353933; 9384377 [H]