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The map label for this gene is pcaH [H]

Identifier: 66045362

GI number: 66045362

Start: 2479963

End: 2480682

Strand: Direct

Name: pcaH [H]

Synonym: Psyr_2122

Alternate gene names: 66045362

Gene position: 2479963-2480682 (Clockwise)

Preceding gene: 66045361

Following gene: 66045363

Centisome position: 40.7

GC content: 59.86

Gene sequence:

>720_bases
ATGTCTGCCGCGGACAACAGCCGCTTCGTCATTCGTGACCGAAACTGGCATCCAAAAGCGCTCACACCTGATTACAAGAC
CTCGATCCTGCGCTCGCCGCGCCAGGCGCTGGTCAGTATCCCGCAGTCCATTTCCGAAACCACCGGCCCGGATTTCTCGC
ATTTGAAATTCGGCCAGCACGATAACGACCTGCTGCTCAATTTCAACAACGGTGGGCTGCCCATCGGTGAGCGTATTCTG
CTGGCCGGGCGGGTCTGCGATCAGTATGGAAAGCCGATCCCGCATACCCTGGTGGAGATCTGGCAGGCCAACGCCGGCGG
GCGTTATCGCCACAAGCGCGATGCCTATCTGGCGCCCATCGATCCCAATTTCGGCGGCGTCGGACGTGCGTTGACCGACA
GCGAAGGCAATTACAGCTTCCGTACCGTCAAGCCAGGGCCTTACCCATGGCGCAACGGTCCCAACGACTGGCGCCCGGCA
CACATTCATGTGTCGATCAGCGGGCCGTCGATTGCCACACGGCTGATCACCCAGTTGTATTTCGAAGGCGATCCGCTGAT
TCCGATCTGCCCGATCGTCAAGGCCATCGCCAACCCGGACGCCGTGCAGAGCCTGATTGCCAGGCTCGACCTGGGCATGG
GCAATCCAATGGATTGCCTGGCGTATCGCTTTGATATCGTGTTGCGCGGCCAGCGCAAGACTCACTTCGAAAACTGCTGA

Upstream 100 bases:

>100_bases
GTTCTCTATAAGCATGGATCGCGCGACACTTCGCCGCAGCCTGTAGCGCATGTGATCGACGCCTGCGCGCCCCATAAGAA
AGAAAAAAGAGGAGAACGCC

Downstream 100 bases:

>100_bases
GGAGGCCCGACATGCCCGTTCAATTGCTGCAGGAAACCCCTTCGCAAACCGCCGGCCCCTACGTCCACATCGGTCTCGCA
CCGCAGGTGGCCGGCAACCC

Product: intradiol ring-cleavage dioxygenase

Products: NA

Alternate protein names: 3,4-PCD [H]

Number of amino acids: Translated: 239; Mature: 238

Protein sequence:

>239_residues
MSAADNSRFVIRDRNWHPKALTPDYKTSILRSPRQALVSIPQSISETTGPDFSHLKFGQHDNDLLLNFNNGGLPIGERIL
LAGRVCDQYGKPIPHTLVEIWQANAGGRYRHKRDAYLAPIDPNFGGVGRALTDSEGNYSFRTVKPGPYPWRNGPNDWRPA
HIHVSISGPSIATRLITQLYFEGDPLIPICPIVKAIANPDAVQSLIARLDLGMGNPMDCLAYRFDIVLRGQRKTHFENC

Sequences:

>Translated_239_residues
MSAADNSRFVIRDRNWHPKALTPDYKTSILRSPRQALVSIPQSISETTGPDFSHLKFGQHDNDLLLNFNNGGLPIGERIL
LAGRVCDQYGKPIPHTLVEIWQANAGGRYRHKRDAYLAPIDPNFGGVGRALTDSEGNYSFRTVKPGPYPWRNGPNDWRPA
HIHVSISGPSIATRLITQLYFEGDPLIPICPIVKAIANPDAVQSLIARLDLGMGNPMDCLAYRFDIVLRGQRKTHFENC
>Mature_238_residues
SAADNSRFVIRDRNWHPKALTPDYKTSILRSPRQALVSIPQSISETTGPDFSHLKFGQHDNDLLLNFNNGGLPIGERILL
AGRVCDQYGKPIPHTLVEIWQANAGGRYRHKRDAYLAPIDPNFGGVGRALTDSEGNYSFRTVKPGPYPWRNGPNDWRPAH
IHVSISGPSIATRLITQLYFEGDPLIPICPIVKAIANPDAVQSLIARLDLGMGNPMDCLAYRFDIVLRGQRKTHFENC

Specific function: Plays an essential role in the utilization of numerous aromatic and hydroaromatic compounds via the beta-ketoadipate pathway [H]

COG id: COG3485

COG function: function code Q; Protocatechuate 3,4-dioxygenase beta subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the intradiol ring-cleavage dioxygenase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000627
- InterPro:   IPR015889
- InterPro:   IPR012785 [H]

Pfam domain/function: PF00775 Dioxygenase_C [H]

EC number: =1.13.11.3 [H]

Molecular weight: Translated: 26665; Mature: 26533

Theoretical pI: Translated: 9.14; Mature: 9.14

Prosite motif: PS00083 INTRADIOL_DIOXYGENAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAADNSRFVIRDRNWHPKALTPDYKTSILRSPRQALVSIPQSISETTGPDFSHLKFGQH
CCCCCCCEEEEECCCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHCCCCCHHHCCCCCC
DNDLLLNFNNGGLPIGERILLAGRVCDQYGKPIPHTLVEIWQANAGGRYRHKRDAYLAPI
CCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCEEECC
DPNFGGVGRALTDSEGNYSFRTVKPGPYPWRNGPNDWRPAHIHVSISGPSIATRLITQLY
CCCCCCCCCEEECCCCCEEEEEECCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHH
FEGDPLIPICPIVKAIANPDAVQSLIARLDLGMGNPMDCLAYRFDIVLRGQRKTHFENC
HCCCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHEEEEEEEECCCCCCCCCC
>Mature Secondary Structure 
SAADNSRFVIRDRNWHPKALTPDYKTSILRSPRQALVSIPQSISETTGPDFSHLKFGQH
CCCCCCEEEEECCCCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHCCCCCHHHCCCCCC
DNDLLLNFNNGGLPIGERILLAGRVCDQYGKPIPHTLVEIWQANAGGRYRHKRDAYLAPI
CCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCEEECC
DPNFGGVGRALTDSEGNYSFRTVKPGPYPWRNGPNDWRPAHIHVSISGPSIATRLITQLY
CCCCCCCCCEEECCCCCEEEEEECCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHH
FEGDPLIPICPIVKAIANPDAVQSLIARLDLGMGNPMDCLAYRFDIVLRGQRKTHFENC
HCCCCCCHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHEEEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8407791; 115853; 3194022; 7990141; 9254599; 9254600; 9298971 [H]