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The map label for this gene is cdsA [H]

Identifier: 66044596

GI number: 66044596

Start: 1527289

End: 1528104

Strand: Direct

Name: cdsA [H]

Synonym: Psyr_1348

Alternate gene names: 66044596

Gene position: 1527289-1528104 (Clockwise)

Preceding gene: 66044595

Following gene: 66044597

Centisome position: 25.06

GC content: 60.42

Gene sequence:

>816_bases
ATGCTGAAACAACGGATCATCACGGCACTCATTCTGTTGCCGATCGCCTTGTGCGGGTTTTTCCTGCTGACCGGCATGTA
CTTCGCCCTGTTCATCGGGGTGGTCGTCGTTCTGGGTGCCTGGGAATGGGCGCGGCTCGCAGGTTTTGCCGCGCAGTTGA
TGCGTATCGGCTATGCGGCTGTGGTCGCTGTTCTGCTTTTCCTCATGTACCTGCTGCCAGGGCTGGAGCCCTGGGTGCTG
GTTGCTGCCGTCATCTGGTGGGGTGTGGCGACCTTTCTGGTCCTTACCTATCCGGACTCCAGCAGTCACTGGGCAAGTGC
AGCGTGCAAGCTGGTCATCGGCCTTCTGATTCTGCTGCCTGCATGGCAGGGTCTGGTCCTGATCAAGCAGTGGCCACTGG
GTAACTGGCTGATTCTGTCGGTGATGGTGCTGGTCTGGGCCGCCGACATCGGCGCTTATTTTTCCGGCAAGGCTTTTGGC
AAGCGCAAGCTGGCGCCCAAGGTGAGCCCTGGCAAGAGCTGGGAGGGCGTATATGGCGGTCTGGTGGTCAGTCTGGGCAT
CACCGCAGCAGTAGGTTTTTCCCGCGACTGGACGGTTGCGCAGTTCATCGCGGCGCTCTTTGGTGCGGCGGTGATCGTAT
TCATCTCGGTGATTGGCGACCTGACCGAAAGCATGTTCAAGCGCCAGTCCGGGGTCAAGGACAGCAGCAATCTGCTGCCT
GGACACGGCGGGGTACTGGACCGCATCGACAGCCTGACGGCGGCCATTCCGGTATTTGCCGTTCTGCTCTGGGCCGCTGA
CTGGGGTGTCATGTGA

Upstream 100 bases:

>100_bases
TCAAACACGATGCCATGCGCGCCGCGCTGGCAGATTTCGCTTCTCGCCAACGTCGCTTCGGTAAAACCAGCGAACAGGTA
GAAGCTGGAGCCCGGGCTTA

Downstream 100 bases:

>100_bases
GTGGTCCGCAACAAATCTCCATTCTGGGCGCAACCGGTTCCATAGGGCTGAGCACTCTGGACGTGGTTGCCCGTCATCCA
GCGCTTTATCAAGTGTTCGC

Product: phosphatidate cytidylyltransferase

Products: NA

Alternate protein names: CDP-DAG synthase; CDP-DG synthase; CDP-diacylglycerol synthase; CDS; CDP-diglyceride pyrophosphorylase; CDP-diglyceride synthase; CTP:phosphatidate cytidylyltransferase [H]

Number of amino acids: Translated: 271; Mature: 271

Protein sequence:

>271_residues
MLKQRIITALILLPIALCGFFLLTGMYFALFIGVVVVLGAWEWARLAGFAAQLMRIGYAAVVAVLLFLMYLLPGLEPWVL
VAAVIWWGVATFLVLTYPDSSSHWASAACKLVIGLLILLPAWQGLVLIKQWPLGNWLILSVMVLVWAADIGAYFSGKAFG
KRKLAPKVSPGKSWEGVYGGLVVSLGITAAVGFSRDWTVAQFIAALFGAAVIVFISVIGDLTESMFKRQSGVKDSSNLLP
GHGGVLDRIDSLTAAIPVFAVLLWAADWGVM

Sequences:

>Translated_271_residues
MLKQRIITALILLPIALCGFFLLTGMYFALFIGVVVVLGAWEWARLAGFAAQLMRIGYAAVVAVLLFLMYLLPGLEPWVL
VAAVIWWGVATFLVLTYPDSSSHWASAACKLVIGLLILLPAWQGLVLIKQWPLGNWLILSVMVLVWAADIGAYFSGKAFG
KRKLAPKVSPGKSWEGVYGGLVVSLGITAAVGFSRDWTVAQFIAALFGAAVIVFISVIGDLTESMFKRQSGVKDSSNLLP
GHGGVLDRIDSLTAAIPVFAVLLWAADWGVM
>Mature_271_residues
MLKQRIITALILLPIALCGFFLLTGMYFALFIGVVVVLGAWEWARLAGFAAQLMRIGYAAVVAVLLFLMYLLPGLEPWVL
VAAVIWWGVATFLVLTYPDSSSHWASAACKLVIGLLILLPAWQGLVLIKQWPLGNWLILSVMVLVWAADIGAYFSGKAFG
KRKLAPKVSPGKSWEGVYGGLVVSLGITAAVGFSRDWTVAQFIAALFGAAVIVFISVIGDLTESMFKRQSGVKDSSNLLP
GHGGVLDRIDSLTAAIPVFAVLLWAADWGVM

Specific function: Phospholipid biosynthesis. [C]

COG id: COG0575

COG function: function code I; CDP-diglyceride synthetase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDS family [H]

Homologues:

Organism=Escherichia coli, GI87081696, Length=280, Percent_Identity=45.7142857142857, Blast_Score=199, Evalue=2e-52,
Organism=Escherichia coli, GI1787677, Length=113, Percent_Identity=45.1327433628319, Blast_Score=92, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000374 [H]

Pfam domain/function: PF01148 CTP_transf_1 [H]

EC number: =2.7.7.41 [H]

Molecular weight: Translated: 29197; Mature: 29197

Theoretical pI: Translated: 9.64; Mature: 9.64

Prosite motif: PS01315 CDS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKQRIITALILLPIALCGFFLLTGMYFALFIGVVVVLGAWEWARLAGFAAQLMRIGYAA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHH
VVAVLLFLMYLLPGLEPWVLVAAVIWWGVATFLVLTYPDSSSHWASAACKLVIGLLILLP
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
AWQGLVLIKQWPLGNWLILSVMVLVWAADIGAYFSGKAFGKRKLAPKVSPGKSWEGVYGG
HCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHH
LVVSLGITAAVGFSRDWTVAQFIAALFGAAVIVFISVIGDLTESMFKRQSGVKDSSNLLP
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
GHGGVLDRIDSLTAAIPVFAVLLWAADWGVM
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLKQRIITALILLPIALCGFFLLTGMYFALFIGVVVVLGAWEWARLAGFAAQLMRIGYAA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHH
VVAVLLFLMYLLPGLEPWVLVAAVIWWGVATFLVLTYPDSSSHWASAACKLVIGLLILLP
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHH
AWQGLVLIKQWPLGNWLILSVMVLVWAADIGAYFSGKAFGKRKLAPKVSPGKSWEGVYGG
HCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHH
LVVSLGITAAVGFSRDWTVAQFIAALFGAAVIVFISVIGDLTESMFKRQSGVKDSSNLLP
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
GHGGVLDRIDSLTAAIPVFAVLLWAADWGVM
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8654980; 10984043 [H]