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The map label for this gene is 62185481

Identifier: 62185481

GI number: 62185481

Start: 1022053

End: 1023435

Strand: Direct

Name: 62185481

Synonym: CAB879

Alternate gene names: NA

Gene position: 1022053-1023435 (Clockwise)

Preceding gene: 62185480

Following gene: 62185482

Centisome position: 89.31

GC content: 41.14

Gene sequence:

>1383_bases
ATGACCGACTCTGTAACCTTCCCGTCTGTCGTGGACATGTCTTCACTAACAGAAAAACTCAAGTCTATTAATCAGGAGCA
TTTATTAGATTCGTGGTCGTCCCTTTCTCAAAAACAACAACAGCGTCTCTATCACCAAATTTCGTCTATAGACATAGACC
TTTTCCATAAACAAAGACAACTGATCACTTCTCCAAGACCTATCCTAAAAGATTTTCATCCCTTAACCTCTTTCACTTCC
TCAGGAGAAGATCCTGAAAGAACTCAAGTAGGGACAAATCTCCTCAAGGAAAAGAAAGTCGCTTGTGTTGTTCTTGCTGG
AGGCCAAGGATCTAGATTGAAATGTGACGGACCTAAAGGCTTGTTCCCTGTATCTCCTATCAAAAAGAAGCCCTTATTCC
AGCTTGTTGCTGAAAAAGTCTGTGCAGCAAGCAAACTGGCAAATCAACCTTTGCCTTTAGCTTTTATGACATCACCTCTA
AATAATCGTCAGACGCGTTCCTATTTCGAATCTAATGATTATTTCCATCTTGATCCCAACCAAGTAGACTTTTTCTGCCA
ACCTCTTTGGCCTTTATTATCCTTATCGGGCGATCTGTTCCTTGAGGATACGGACACTTTATCCTTAGGGCCTAATGGAA
ATGGTTGCCTAGCAACTCTTCTCTATACCTCAGGGTTATGGGAAAAATGGAAGAAAGCAGGAATTGAAATGGTGAGCGTG
ATCCCTATCGACAATCCTCTAGCCCTACCTTTTGATGTAGAACTTTGTGGATTCCATGGTATGGAAAATAACGATGTCAC
TATTAAAGCTGCTTTACGACAAACCGCGATTGAAGATGTGGGCATCTTAGTCAAATCTAATGACTCTGGGAAAACCTCCG
TCATTGAATATTCTGAAATACCCCAAAATGAAAGATTTGCTACGAACTCGGATGGCACGCTAAAGTATTGCCTAGCCAAT
ATCGGTCTCTATTGCTTATCTATGGATTTCATTGCCCATGCGGCCATGCGCGAACTTCCTCTTTATAAAGCTCATAAACA
TGCAAAACAGTTAGGGCTATATTCCTCAGAGAAAAACTCTTGGAAATTCGAAGAATTTATCTTCGACCTCTTTTGCTATA
GCGAACGTTGCCAAACGCTTGTGTACCCCCGTCAAGAATGTTTCGCACCACTAAAAAATCTTGAAGGCAACCATAGTCCT
GCTACTGTCAGAGAAGCTCTTTCCGCTAGGGAACGTCAAATCTTCCATAAAGTTACTGGGAAAAAACTTTCTCCAAACAC
AACATTTGAATTAGAAGCCGATTTTTATTATCCTTCAACCTCTACTTCCCTACACTGGGAAAATAAAGCGTTTTTCGAGG
AACCATTTTTTGAGGCCTCATGA

Upstream 100 bases:

>100_bases
GTAAATTACTAGAATTAATTAACCGTAGAAAAATCATCGAAAAGATCAAGAATAATAAGTATTCTAAATATCAAGAGATA
GGAACGCAAGGCTAACTGTA

Downstream 100 bases:

>100_bases
AAGAGAAAATTGCCTACTTAGGTATGGGCATTTGGGGATTTTGCCTTGCTTCCTTATTAGCGCATAAGGGTTATCGTGTA
GTAGGATGGGCTCGTAATCC

Product: putative UDP-N-acetylhexosamine pyrophosphorylase

Products: diphosphate; UDP-N-acetyl-D-glucosamine

Alternate protein names: NA

Number of amino acids: Translated: 460; Mature: 459

Protein sequence:

>460_residues
MTDSVTFPSVVDMSSLTEKLKSINQEHLLDSWSSLSQKQQQRLYHQISSIDIDLFHKQRQLITSPRPILKDFHPLTSFTS
SGEDPERTQVGTNLLKEKKVACVVLAGGQGSRLKCDGPKGLFPVSPIKKKPLFQLVAEKVCAASKLANQPLPLAFMTSPL
NNRQTRSYFESNDYFHLDPNQVDFFCQPLWPLLSLSGDLFLEDTDTLSLGPNGNGCLATLLYTSGLWEKWKKAGIEMVSV
IPIDNPLALPFDVELCGFHGMENNDVTIKAALRQTAIEDVGILVKSNDSGKTSVIEYSEIPQNERFATNSDGTLKYCLAN
IGLYCLSMDFIAHAAMRELPLYKAHKHAKQLGLYSSEKNSWKFEEFIFDLFCYSERCQTLVYPRQECFAPLKNLEGNHSP
ATVREALSARERQIFHKVTGKKLSPNTTFELEADFYYPSTSTSLHWENKAFFEEPFFEAS

Sequences:

>Translated_460_residues
MTDSVTFPSVVDMSSLTEKLKSINQEHLLDSWSSLSQKQQQRLYHQISSIDIDLFHKQRQLITSPRPILKDFHPLTSFTS
SGEDPERTQVGTNLLKEKKVACVVLAGGQGSRLKCDGPKGLFPVSPIKKKPLFQLVAEKVCAASKLANQPLPLAFMTSPL
NNRQTRSYFESNDYFHLDPNQVDFFCQPLWPLLSLSGDLFLEDTDTLSLGPNGNGCLATLLYTSGLWEKWKKAGIEMVSV
IPIDNPLALPFDVELCGFHGMENNDVTIKAALRQTAIEDVGILVKSNDSGKTSVIEYSEIPQNERFATNSDGTLKYCLAN
IGLYCLSMDFIAHAAMRELPLYKAHKHAKQLGLYSSEKNSWKFEEFIFDLFCYSERCQTLVYPRQECFAPLKNLEGNHSP
ATVREALSARERQIFHKVTGKKLSPNTTFELEADFYYPSTSTSLHWENKAFFEEPFFEAS
>Mature_459_residues
TDSVTFPSVVDMSSLTEKLKSINQEHLLDSWSSLSQKQQQRLYHQISSIDIDLFHKQRQLITSPRPILKDFHPLTSFTSS
GEDPERTQVGTNLLKEKKVACVVLAGGQGSRLKCDGPKGLFPVSPIKKKPLFQLVAEKVCAASKLANQPLPLAFMTSPLN
NRQTRSYFESNDYFHLDPNQVDFFCQPLWPLLSLSGDLFLEDTDTLSLGPNGNGCLATLLYTSGLWEKWKKAGIEMVSVI
PIDNPLALPFDVELCGFHGMENNDVTIKAALRQTAIEDVGILVKSNDSGKTSVIEYSEIPQNERFATNSDGTLKYCLANI
GLYCLSMDFIAHAAMRELPLYKAHKHAKQLGLYSSEKNSWKFEEFIFDLFCYSERCQTLVYPRQECFAPLKNLEGNHSPA
TVREALSARERQIFHKVTGKKLSPNTTFELEADFYYPSTSTSLHWENKAFFEEPFFEAS

Specific function: Unknown

COG id: COG4284

COG function: function code G; UDP-glucose pyrophosphorylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDPGP type 1 family [H]

Homologues:

Organism=Homo sapiens, GI187936958, Length=421, Percent_Identity=31.1163895486936, Blast_Score=168, Evalue=8e-42,
Organism=Homo sapiens, GI156627575, Length=432, Percent_Identity=27.7777777777778, Blast_Score=168, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI17552518, Length=436, Percent_Identity=27.7522935779816, Blast_Score=115, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI193206427, Length=339, Percent_Identity=27.7286135693215, Blast_Score=87, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6320100, Length=428, Percent_Identity=31.5420560747664, Blast_Score=153, Evalue=4e-38,
Organism=Drosophila melanogaster, GI19920822, Length=474, Percent_Identity=27.4261603375527, Blast_Score=157, Evalue=1e-38,
Organism=Drosophila melanogaster, GI24582229, Length=470, Percent_Identity=27.2340425531915, Blast_Score=154, Evalue=2e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002618 [H]

Pfam domain/function: PF01704 UDPGP [H]

EC number: 2.7.7.23

Molecular weight: Translated: 51883; Mature: 51751

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDSVTFPSVVDMSSLTEKLKSINQEHLLDSWSSLSQKQQQRLYHQISSIDIDLFHKQRQ
CCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
LITSPRPILKDFHPLTSFTSSGEDPERTQVGTNLLKEKKVACVVLAGGQGSRLKCDGPKG
HHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCEEEECCCCC
LFPVSPIKKKPLFQLVAEKVCAASKLANQPLPLAFMTSPLNNRQTRSYFESNDYFHLDPN
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHCCCCEEEECCC
QVDFFCQPLWPLLSLSGDLFLEDTDTLSLGPNGNGCLATLLYTSGLWEKWKKAGIEMVSV
CCHHHHHHHHHHHHCCCCEEEECCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCEEEEE
IPIDNPLALPFDVELCGFHGMENNDVTIKAALRQTAIEDVGILVKSNDSGKTSVIEYSEI
EECCCCCCCCEEEEEECCCCCCCCCEEEEHHHHHHHHHHCEEEEECCCCCCEEEEEHHHC
PQNERFATNSDGTLKYCLANIGLYCLSMDFIAHAAMRELPLYKAHKHAKQLGLYSSEKNS
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCC
WKFEEFIFDLFCYSERCQTLVYPRQECFAPLKNLEGNHSPATVREALSARERQIFHKVTG
CHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCC
KKLSPNTTFELEADFYYPSTSTSLHWENKAFFEEPFFEAS
CCCCCCCEEEEEEEEECCCCCCEEEECCCCHHCCCCCCCC
>Mature Secondary Structure 
TDSVTFPSVVDMSSLTEKLKSINQEHLLDSWSSLSQKQQQRLYHQISSIDIDLFHKQRQ
CCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
LITSPRPILKDFHPLTSFTSSGEDPERTQVGTNLLKEKKVACVVLAGGQGSRLKCDGPKG
HHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCEEEEEEECCCCCEEEECCCCC
LFPVSPIKKKPLFQLVAEKVCAASKLANQPLPLAFMTSPLNNRQTRSYFESNDYFHLDPN
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCHHHHHHCCCCEEEECCC
QVDFFCQPLWPLLSLSGDLFLEDTDTLSLGPNGNGCLATLLYTSGLWEKWKKAGIEMVSV
CCHHHHHHHHHHHHCCCCEEEECCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCEEEEE
IPIDNPLALPFDVELCGFHGMENNDVTIKAALRQTAIEDVGILVKSNDSGKTSVIEYSEI
EECCCCCCCCEEEEEECCCCCCCCCEEEEHHHHHHHHHHCEEEEECCCCCCEEEEEHHHC
PQNERFATNSDGTLKYCLANIGLYCLSMDFIAHAAMRELPLYKAHKHAKQLGLYSSEKNS
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCC
WKFEEFIFDLFCYSERCQTLVYPRQECFAPLKNLEGNHSPATVREALSARERQIFHKVTG
CHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCC
KKLSPNTTFELEADFYYPSTSTSLHWENKAFFEEPFFEAS
CCCCCCCEEEEEEEEECCCCCCEEEECCCCHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: UTP; N-acetyl-alpha-D-glucosamine 1-phosphate

Specific reaction: UTP + N-acetyl-alpha-D-glucosamine 1-phosphate = diphosphate + UDP-N-acetyl-D-glucosamine

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA