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The map label for this gene is gpsA

Identifier: 62185482

GI number: 62185482

Start: 1023432

End: 1024436

Strand: Direct

Name: gpsA

Synonym: CAB880

Alternate gene names: 62185482

Gene position: 1023432-1024436 (Clockwise)

Preceding gene: 62185481

Following gene: 62185483

Centisome position: 89.43

GC content: 44.88

Gene sequence:

>1005_bases
ATGAAAGAGAAAATTGCCTACTTAGGTATGGGCATTTGGGGATTTTGCCTTGCTTCCTTATTAGCGCATAAGGGTTATCG
TGTAGTAGGATGGGCTCGTAATCCTGAATTAGTTGCGCAACTACAAACTGAGCACCGGCATCCCCAAGCTCCTGATATGC
CAATCCATCCGAATTTGTCATTCACTACAGATATGGTGGAGGCGGTGGACGGTGCTTCCATGATTGTGGAGGCGGTCTCT
TCCGCAGGAATACGCCCAGTATCTAAACAGCTAAAAACAATTACCGACCTCAAGGTGCCTTTTGTCATTACCTCTAAAGG
TATTGAGCAGCATACCGGACTCCTCCTCAGTGAAATCGTTGTGGAGATTTTCGGCAGCCAGGCTTCCCGATATCTCGGTT
ATCTCAGCGGGCCTTCTATAGCAAGAGAAGTCCTTAAAGGCTGTCCTTGTTCTGTTGTCATCAGTGCGTATGACCCTGAC
ACCTTGAAAAAAATACATCATGCTTTTCTCACCCCGAAGTTTCGTGTGTATCCCAACAGTGATCTTAAAGGCGTAGCTCT
CGGTGGTGCTCTAAAAAATATCATCGCTATTGCCTGTGGGATTTCTGATGGATTCCAATTTGGAGATAACGCTAAGTCAG
GATTAGTCACTCGTGGTCTTCATGAAATACGCAAATTTGCCACGATCATGGACTGCCGCCCCGATACGCTCTATGGCTTA
GCCGGCCTTGGAGATCTTTGTACAACCTGTTTTTCTTCACTAAGTAGAAACACGAGGTTTGGGAAGCTCATAGCTCAGGG
ATTCACTCTCGAACAAGCAAAAGCAGAAATCGGCATGGTTGTAGAAGGTGCGTATACAGCCCTTTCCGCATATCAAATTG
CTAAACATCATAAAATCGATATGCCGATCACTACAGGCATCTACCGCGTTTTATATGAAAATCTCGATATCAAAGAAGGT
ATCGCTGCACTCTTACAAAGAAATACTAAGGAAGAATATCTTTAA

Upstream 100 bases:

>100_bases
CAACATTTGAATTAGAAGCCGATTTTTATTATCCTTCAACCTCTACTTCCCTACACTGGGAAAATAAAGCGTTTTTCGAG
GAACCATTTTTTGAGGCCTC

Downstream 100 bases:

>100_bases
ACATGGAGATAGGCTCTATTTGCTCATCTCCTTAGACAGAAGGCTCCTCCTACTGAGTTTTCATTTGTACATTTTTTTAC
CATTTGTTAAAGATGAATTT

Product: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MKEKIAYLGMGIWGFCLASLLAHKGYRVVGWARNPELVAQLQTEHRHPQAPDMPIHPNLSFTTDMVEAVDGASMIVEAVS
SAGIRPVSKQLKTITDLKVPFVITSKGIEQHTGLLLSEIVVEIFGSQASRYLGYLSGPSIAREVLKGCPCSVVISAYDPD
TLKKIHHAFLTPKFRVYPNSDLKGVALGGALKNIIAIACGISDGFQFGDNAKSGLVTRGLHEIRKFATIMDCRPDTLYGL
AGLGDLCTTCFSSLSRNTRFGKLIAQGFTLEQAKAEIGMVVEGAYTALSAYQIAKHHKIDMPITTGIYRVLYENLDIKEG
IAALLQRNTKEEYL

Sequences:

>Translated_334_residues
MKEKIAYLGMGIWGFCLASLLAHKGYRVVGWARNPELVAQLQTEHRHPQAPDMPIHPNLSFTTDMVEAVDGASMIVEAVS
SAGIRPVSKQLKTITDLKVPFVITSKGIEQHTGLLLSEIVVEIFGSQASRYLGYLSGPSIAREVLKGCPCSVVISAYDPD
TLKKIHHAFLTPKFRVYPNSDLKGVALGGALKNIIAIACGISDGFQFGDNAKSGLVTRGLHEIRKFATIMDCRPDTLYGL
AGLGDLCTTCFSSLSRNTRFGKLIAQGFTLEQAKAEIGMVVEGAYTALSAYQIAKHHKIDMPITTGIYRVLYENLDIKEG
IAALLQRNTKEEYL
>Mature_334_residues
MKEKIAYLGMGIWGFCLASLLAHKGYRVVGWARNPELVAQLQTEHRHPQAPDMPIHPNLSFTTDMVEAVDGASMIVEAVS
SAGIRPVSKQLKTITDLKVPFVITSKGIEQHTGLLLSEIVVEIFGSQASRYLGYLSGPSIAREVLKGCPCSVVISAYDPD
TLKKIHHAFLTPKFRVYPNSDLKGVALGGALKNIIAIACGISDGFQFGDNAKSGLVTRGLHEIRKFATIMDCRPDTLYGL
AGLGDLCTTCFSSLSRNTRFGKLIAQGFTLEQAKAEIGMVVEGAYTALSAYQIAKHHKIDMPITTGIYRVLYENLDIKEG
IAALLQRNTKEEYL

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family

Homologues:

Organism=Homo sapiens, GI33695088, Length=343, Percent_Identity=27.9883381924198, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI24307999, Length=345, Percent_Identity=27.2463768115942, Blast_Score=107, Evalue=1e-23,
Organism=Escherichia coli, GI1790037, Length=332, Percent_Identity=37.0481927710843, Blast_Score=218, Evalue=6e-58,
Organism=Caenorhabditis elegans, GI17507425, Length=338, Percent_Identity=26.3313609467456, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI32564399, Length=332, Percent_Identity=26.2048192771084, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI193210136, Length=341, Percent_Identity=26.099706744868, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI32564403, Length=341, Percent_Identity=26.099706744868, Blast_Score=95, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI193210134, Length=209, Percent_Identity=29.1866028708134, Blast_Score=80, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6320181, Length=348, Percent_Identity=27.8735632183908, Blast_Score=102, Evalue=9e-23,
Organism=Saccharomyces cerevisiae, GI6324513, Length=363, Percent_Identity=26.9972451790634, Blast_Score=98, Evalue=2e-21,
Organism=Drosophila melanogaster, GI17136204, Length=336, Percent_Identity=24.1071428571429, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI17136202, Length=336, Percent_Identity=24.1071428571429, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI17136200, Length=336, Percent_Identity=24.1071428571429, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI22026922, Length=286, Percent_Identity=24.4755244755245, Blast_Score=85, Evalue=8e-17,
Organism=Drosophila melanogaster, GI24648969, Length=252, Percent_Identity=25, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GPDA_CHLAB (Q5L4X5)

Other databases:

- EMBL:   CR848038
- RefSeq:   YP_220267.1
- ProteinModelPortal:   Q5L4X5
- SMR:   Q5L4X5
- GeneID:   3338027
- GenomeReviews:   CR848038_GR
- KEGG:   cab:CAB880
- HOGENOM:   HBG586392
- OMA:   SQTLRGN
- PhylomeDB:   Q5L4X5
- ProtClustDB:   PRK00094
- BioCyc:   CABO218497:CAB880-MONOMER
- BRENDA:   1.1.1.94
- HAMAP:   MF_00394
- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- Gene3D:   G3DSA:1.10.1040.10
- PANTHER:   PTHR11728
- PIRSF:   PIRSF000114
- PRINTS:   PR00077

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N; SSF48179 6DGDH_C_like

EC number: =1.1.1.94

Molecular weight: Translated: 36417; Mature: 36417

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: PS00957 NAD_G3PDH

Important sites: ACT_SITE 192-192 BINDING 106-106 BINDING 106-106 BINDING 141-141 BINDING 256-256 BINDING 282-282

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEKIAYLGMGIWGFCLASLLAHKGYRVVGWARNPELVAQLQTEHRHPQAPDMPIHPNLS
CCCCHHHHCCCHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCC
FTTDMVEAVDGASMIVEAVSSAGIRPVSKQLKTITDLKVPFVITSKGIEQHTGLLLSEIV
HHHHHHHHHCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHH
VEIFGSQASRYLGYLSGPSIAREVLKGCPCSVVISAYDPDTLKKIHHAFLTPKFRVYPNS
HHHHCCHHHHHHHCCCCHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHCCCCEEECCCC
DLKGVALGGALKNIIAIACGISDGFQFGDNAKSGLVTRGLHEIRKFATIMDCRPDTLYGL
CCCCEEHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHH
AGLGDLCTTCFSSLSRNTRFGKLIAQGFTLEQAKAEIGMVVEGAYTALSAYQIAKHHKID
HHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHCEEEHHHHHHHHHHHHHHHCCCC
MPITTGIYRVLYENLDIKEGIAALLQRNTKEEYL
CCHHHHHHHHHHHCCCHHHHHHHHHHCCCHHCCC
>Mature Secondary Structure
MKEKIAYLGMGIWGFCLASLLAHKGYRVVGWARNPELVAQLQTEHRHPQAPDMPIHPNLS
CCCCHHHHCCCHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHCCCCCCCCCCCCCCCC
FTTDMVEAVDGASMIVEAVSSAGIRPVSKQLKTITDLKVPFVITSKGIEQHTGLLLSEIV
HHHHHHHHHCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHH
VEIFGSQASRYLGYLSGPSIAREVLKGCPCSVVISAYDPDTLKKIHHAFLTPKFRVYPNS
HHHHCCHHHHHHHCCCCHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHCCCCEEECCCC
DLKGVALGGALKNIIAIACGISDGFQFGDNAKSGLVTRGLHEIRKFATIMDCRPDTLYGL
CCCCEEHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHH
AGLGDLCTTCFSSLSRNTRFGKLIAQGFTLEQAKAEIGMVVEGAYTALSAYQIAKHHKID
HHHHHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHCEEEHHHHHHHHHHHHHHHCCCC
MPITTGIYRVLYENLDIKEGIAALLQRNTKEEYL
CCHHHHHHHHHHHCCCHHHHHHHHHHCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA