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The map label for this gene is xerD [H]

Identifier: 62185317

GI number: 62185317

Start: 815452

End: 816351

Strand: Direct

Name: xerD [H]

Synonym: CAB704

Alternate gene names: 62185317

Gene position: 815452-816351 (Clockwise)

Preceding gene: 62185312

Following gene: 62185319

Centisome position: 71.26

GC content: 45.11

Gene sequence:

>900_bases
ATGACCTCAGCCCAGTTTTGCGATGCTATCCTTGAACAATTTACTCTTTTTCTATCAGTAGATCGCGGTCTTAGCTCCAA
TTCGATTTCCGCCTATTGTCAGGACATTACCTTATTCCTAAAAATCAACACCATTACATCAATTGCAGAAATCTCTCAAG
ACAGTGTGCATCTGTTCGTTCGTCAGCTACATAAACGCAAAGAAGCTGAAGCCACTTTAGCACGTCGTCTCATCGCCCTA
AAAGTATTCTTTCGATTTCTCAAAGAGGCGAAGCTTCTTGAACACCCCCCTCTGATCGAGCATCCCAAAATTTGGAAACG
CCTACCCACTGTACTCACGCCACAAGAAGTGGATGCCCTTTTAGCGATTCCTAAGAAAACGCCAACCTCTTCTCTCATCT
CTACTCGAGATACGGCTATTCTCCATACGTTATACTCTACAGGTATACGTGTATCTGAGCTCTGCGGTTTACACATCGGA
GATGTTAGCGATGACTTTCTTCGCGTTACAGGGAAAGGTTCGAAAACACGACTTGTTCCCTTAGGGAAACTTGCGAGCGC
AGCCATTGACGCCTATCTCTGTCCTTTTCGAGAAAACCTCCAAAAGAAACAATCTGAAGAGCACCACCTATTTCTCTCTA
TACGCGGACATAAACTCGAGCGTTCTTGCGTATGGAAAAGAATCCATTATTACGCAAAGCAAGTCACCCACAAACGCGTC
TCACCCCACTCGCTAAGGCATGCCTTTGCTACTCACTTATTAGACAACAAGGCCGACCTCAGAGTCATTCAAGAAATGCT
CGGTCATGCACGCATTGCCTCTACAGAAGTCTATACACATGTAGCCGCAGATACCCTAATGGAAAACTTTCTTTCCTATC
ACCCGAGGAATCTCTCCTAA

Upstream 100 bases:

>100_bases
GGCTATCTAAAAAGCCTTTTCTATCCATCATCTACCTCATCCTAGCTTAAAATCTACCTACAACCTATACTAAAAACTAG
ACCAGCCGAAGTTCGATTTT

Downstream 100 bases:

>100_bases
TCACATTGATAGAAAAACGTTCCGTTCTCTAGGTGAGAATAGCAGTCTTCATGTCCTTGTGATGTTCCAGTATATCCTCC
ATAAGTCTCAGGATAATAAT

Product: site-specific tyrosine recombinase XerD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 298

Protein sequence:

>299_residues
MTSAQFCDAILEQFTLFLSVDRGLSSNSISAYCQDITLFLKINTITSIAEISQDSVHLFVRQLHKRKEAEATLARRLIAL
KVFFRFLKEAKLLEHPPLIEHPKIWKRLPTVLTPQEVDALLAIPKKTPTSSLISTRDTAILHTLYSTGIRVSELCGLHIG
DVSDDFLRVTGKGSKTRLVPLGKLASAAIDAYLCPFRENLQKKQSEEHHLFLSIRGHKLERSCVWKRIHYYAKQVTHKRV
SPHSLRHAFATHLLDNKADLRVIQEMLGHARIASTEVYTHVAADTLMENFLSYHPRNLS

Sequences:

>Translated_299_residues
MTSAQFCDAILEQFTLFLSVDRGLSSNSISAYCQDITLFLKINTITSIAEISQDSVHLFVRQLHKRKEAEATLARRLIAL
KVFFRFLKEAKLLEHPPLIEHPKIWKRLPTVLTPQEVDALLAIPKKTPTSSLISTRDTAILHTLYSTGIRVSELCGLHIG
DVSDDFLRVTGKGSKTRLVPLGKLASAAIDAYLCPFRENLQKKQSEEHHLFLSIRGHKLERSCVWKRIHYYAKQVTHKRV
SPHSLRHAFATHLLDNKADLRVIQEMLGHARIASTEVYTHVAADTLMENFLSYHPRNLS
>Mature_298_residues
TSAQFCDAILEQFTLFLSVDRGLSSNSISAYCQDITLFLKINTITSIAEISQDSVHLFVRQLHKRKEAEATLARRLIALK
VFFRFLKEAKLLEHPPLIEHPKIWKRLPTVLTPQEVDALLAIPKKTPTSSLISTRDTAILHTLYSTGIRVSELCGLHIGD
VSDDFLRVTGKGSKTRLVPLGKLASAAIDAYLCPFRENLQKKQSEEHHLFLSIRGHKLERSCVWKRIHYYAKQVTHKRVS
PHSLRHAFATHLLDNKADLRVIQEMLGHARIASTEVYTHVAADTLMENFLSYHPRNLS

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=297, Percent_Identity=38.047138047138, Blast_Score=172, Evalue=2e-44,
Organism=Escherichia coli, GI1790244, Length=294, Percent_Identity=34.6938775510204, Blast_Score=147, Evalue=6e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 33979; Mature: 33848

Theoretical pI: Translated: 9.93; Mature: 9.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSAQFCDAILEQFTLFLSVDRGLSSNSISAYCQDITLFLKINTITSIAEISQDSVHLFV
CCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHEEEEEEECHHHHHHHHCHHHHHHHH
RQLHKRKEAEATLARRLIALKVFFRFLKEAKLLEHPPLIEHPKIWKRLPTVLTPQEVDAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCHHHHHHH
LAIPKKTPTSSLISTRDTAILHTLYSTGIRVSELCGLHIGDVSDDFLRVTGKGSKTRLVP
HCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCEEEECCCCCEEEEE
LGKLASAAIDAYLCPFRENLQKKQSEEHHLFLSIRGHKLERSCVWKRIHYYAKQVTHKRV
HHHHHHHHHHHHHCHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCC
SPHSLRHAFATHLLDNKADLRVIQEMLGHARIASTEVYTHVAADTLMENFLSYHPRNLS
CHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TSAQFCDAILEQFTLFLSVDRGLSSNSISAYCQDITLFLKINTITSIAEISQDSVHLFV
CHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHEEEEEEECHHHHHHHHCHHHHHHHH
RQLHKRKEAEATLARRLIALKVFFRFLKEAKLLEHPPLIEHPKIWKRLPTVLTPQEVDAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCHHHHHHH
LAIPKKTPTSSLISTRDTAILHTLYSTGIRVSELCGLHIGDVSDDFLRVTGKGSKTRLVP
HCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCEEEECCCCCEEEEE
LGKLASAAIDAYLCPFRENLQKKQSEEHHLFLSIRGHKLERSCVWKRIHYYAKQVTHKRV
HHHHHHHHHHHHHCHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHCC
SPHSLRHAFATHLLDNKADLRVIQEMLGHARIASTEVYTHVAADTLMENFLSYHPRNLS
CHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]