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The map label for this gene is proX [H]

Identifier: 59711392

GI number: 59711392

Start: 858669

End: 859676

Strand: Reverse

Name: proX [H]

Synonym: VF_0785

Alternate gene names: 59711392

Gene position: 859676-858669 (Counterclockwise)

Preceding gene: 59711393

Following gene: 59711391

Centisome position: 29.67

GC content: 38.1

Gene sequence:

>1008_bases
ATGATTAATTCATGGAAGAAAGCACTAACAGCCAGTATCGTTTCGACATTAGCTTTATCTACTAATGTTTGGGCTGAAAA
GCTTCCAGGAGAAGGAGTTAGCGTTCAAGCTCTTCAATCAACAGTTGCTGAAGAAACATTTCAAACCTCGATTGTAAATC
GCGCTCTTGAAGAACTTGGTTATGATGTACAACCAACAAAAGAAGTGGATTATAACGTTGCTTACACATCAATTGCTAAA
GGCGATGCAACATTTCTTGCTGTTGGATGGTTCCCTCTTCATGCCGATAAATACACAATGTCTGGTGGAGATGACAAATT
CTACCGTCAAGGCCAATACGTAAGTGGCGCAGCTCAAGGTTACTTAATTGATAAAAAAACAGCAGAGAAATATGGCATCA
CTAATATTGGTCAATTAAAAGATCCAAAGATAGCTAAATTATTTGATGCTGATGGTGATGGCAAAGCGGATCTTACTGGT
TGTAATCCTGGTTGGGGCTGCGAAATGGTAATCGAACACCAAATTGAGACTTATCAACTTGAAGATACTGTCACACATAA
CCAAGGTAACTACGCAGCAATTATTGCTGATACGATTTCACGTTATAAAAATGGCGAGCCAATTCTCTACTATACGTGGA
CACCTTACTGGGTAAGTGGTGTTCTAGTACCAAATAAAGACGTTGTTTGGTTAGAAGTTCCTTTCTCTGCATTACCGGGT
GAACGTAAAAATGTAGATACCACATTATCAAATGGTAAAAACTACGGTTTTGAAATGAACTCTATGCGTATTATTGCGAA
TAAAGAATTTGCTGCACAAAACCCAGCGGCTGCAAAGTTATTTGAAATAATTAAGCTAAACATCAACGATGTGAGTGCGC
AAAACATGATGATGAGTAAAGGTAAAAACAGCACTGCTGATATTGAATCTCACGTCAATGGTTGGATAAAAGCAAACCGT
AATTTATTTGACTCTTGGATAAATGAAGCGAAAAAAGCAGCCATGTAA

Upstream 100 bases:

>100_bases
AATTACGTTGGTATCAAATAGGACCTGTCGCCATCTTACTAAAAATATTTGCTCAAAAAAAAGAACCAAAACAAGAACTG
AAACTTAAGGAGAAATAAGA

Downstream 100 bases:

>100_bases
TCCTTCATCATACTCCCAAAAAAGCCAATAGCATTATTGGCTTTTTTTGTTTTATACACACAATCTCACACTCGAATTAT
CAATTCTATAACCCCTACTT

Product: glycine betaine transporter periplasmic subunit

Products: ADP; phosphate; L-proline [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MINSWKKALTASIVSTLALSTNVWAEKLPGEGVSVQALQSTVAEETFQTSIVNRALEELGYDVQPTKEVDYNVAYTSIAK
GDATFLAVGWFPLHADKYTMSGGDDKFYRQGQYVSGAAQGYLIDKKTAEKYGITNIGQLKDPKIAKLFDADGDGKADLTG
CNPGWGCEMVIEHQIETYQLEDTVTHNQGNYAAIIADTISRYKNGEPILYYTWTPYWVSGVLVPNKDVVWLEVPFSALPG
ERKNVDTTLSNGKNYGFEMNSMRIIANKEFAAQNPAAAKLFEIIKLNINDVSAQNMMMSKGKNSTADIESHVNGWIKANR
NLFDSWINEAKKAAM

Sequences:

>Translated_335_residues
MINSWKKALTASIVSTLALSTNVWAEKLPGEGVSVQALQSTVAEETFQTSIVNRALEELGYDVQPTKEVDYNVAYTSIAK
GDATFLAVGWFPLHADKYTMSGGDDKFYRQGQYVSGAAQGYLIDKKTAEKYGITNIGQLKDPKIAKLFDADGDGKADLTG
CNPGWGCEMVIEHQIETYQLEDTVTHNQGNYAAIIADTISRYKNGEPILYYTWTPYWVSGVLVPNKDVVWLEVPFSALPG
ERKNVDTTLSNGKNYGFEMNSMRIIANKEFAAQNPAAAKLFEIIKLNINDVSAQNMMMSKGKNSTADIESHVNGWIKANR
NLFDSWINEAKKAAM
>Mature_335_residues
MINSWKKALTASIVSTLALSTNVWAEKLPGEGVSVQALQSTVAEETFQTSIVNRALEELGYDVQPTKEVDYNVAYTSIAK
GDATFLAVGWFPLHADKYTMSGGDDKFYRQGQYVSGAAQGYLIDKKTAEKYGITNIGQLKDPKIAKLFDADGDGKADLTG
CNPGWGCEMVIEHQIETYQLEDTVTHNQGNYAAIIADTISRYKNGEPILYYTWTPYWVSGVLVPNKDVVWLEVPFSALPG
ERKNVDTTLSNGKNYGFEMNSMRIIANKEFAAQNPAAAKLFEIIKLNINDVSAQNMMMSKGKNSTADIESHVNGWIKANR
NLFDSWINEAKKAAM

Specific function: Member of a multicomponent binding-protein-dependent transport system (the proU transporter) which serves as the glycine betaine/L-proline transporter [H]

COG id: COG2113

COG function: function code E; ABC-type proline/glycine betaine transport systems, periplasmic components

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789034, Length=325, Percent_Identity=64.9230769230769, Blast_Score=446, Evalue=1e-126,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007210 [H]

Pfam domain/function: PF04069 OpuAC [H]

EC number: NA

Molecular weight: Translated: 37029; Mature: 37029

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINSWKKALTASIVSTLALSTNVWAEKLPGEGVSVQALQSTVAEETFQTSIVNRALEELG
CCCHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
YDVQPTKEVDYNVAYTSIAKGDATFLAVGWFPLHADKYTMSGGDDKFYRQGQYVSGAAQG
CCCCCCCCCCCEEEEEEECCCCEEEEEEEEEEECCCEEEECCCCHHHHHCCCEECCCCCE
YLIDKKTAEKYGITNIGQLKDPKIAKLFDADGDGKADLTGCNPGWGCEMVIEHQIETYQL
EEEECCCHHHCCCCCCCCCCCCCEEEEECCCCCCCEEECCCCCCCCCEEEEECCCEEEEE
EDTVTHNQGNYAAIIADTISRYKNGEPILYYTWTPYWVSGVLVPNKDVVWLEVPFSALPG
CCCEEECCCCEEEEEEHHHHHHCCCCCEEEEEECHHHEEEEEECCCCEEEEEECHHHCCC
ERKNVDTTLSNGKNYGFEMNSMRIIANKEFAAQNPAAAKLFEIIKLNINDVSAQNMMMSK
CCCCCCHHHCCCCCCCEEECCEEEEECCCCCCCCCHHHHHHHHHEECCCCCCHHHHHHHC
GKNSTADIESHVNGWIKANRNLFDSWINEAKKAAM
CCCCCHHHHHHCCCCEECCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MINSWKKALTASIVSTLALSTNVWAEKLPGEGVSVQALQSTVAEETFQTSIVNRALEELG
CCCHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
YDVQPTKEVDYNVAYTSIAKGDATFLAVGWFPLHADKYTMSGGDDKFYRQGQYVSGAAQG
CCCCCCCCCCCEEEEEEECCCCEEEEEEEEEEECCCEEEECCCCHHHHHCCCEECCCCCE
YLIDKKTAEKYGITNIGQLKDPKIAKLFDADGDGKADLTGCNPGWGCEMVIEHQIETYQL
EEEECCCHHHCCCCCCCCCCCCCEEEEECCCCCCCEEECCCCCCCCCEEEEECCCEEEEE
EDTVTHNQGNYAAIIADTISRYKNGEPILYYTWTPYWVSGVLVPNKDVVWLEVPFSALPG
CCCEEECCCCEEEEEEHHHHHHCCCCCEEEEEECHHHEEEEEECCCCEEEEEECHHHCCC
ERKNVDTTLSNGKNYGFEMNSMRIIANKEFAAQNPAAAKLFEIIKLNINDVSAQNMMMSK
CCCCCCHHHCCCCCCCEEECCEEEEECCCCCCCCCHHHHHHHHHEECCCCCCHHHHHHHC
GKNSTADIESHVNGWIKANRNLFDSWINEAKKAAM
CCCCCHHHHHHCCCCEECCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; L-proline [Periplasm]; H2O [C]

Specific reaction: ATP + L-proline [Periplasm] + H2O = ADP + phosphate + L-proline [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]