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The map label for this gene is yqhT [H]

Identifier: 57651924

GI number: 57651924

Start: 1622165

End: 1623226

Strand: Reverse

Name: yqhT [H]

Synonym: SACOL1588

Alternate gene names: 57651924

Gene position: 1623226-1622165 (Counterclockwise)

Preceding gene: 57651927

Following gene: 57651923

Centisome position: 57.78

GC content: 32.39

Gene sequence:

>1062_bases
ATGAGCAGAATAACACAAGTGCATCGTATTTTAGAACAAAAACATTTAGATGCGATTATCATTCTTTCGGATTACAATAG
AAGATATTTATCAGGTTTTACTGGTACCAGTGGAGCACTTATCATATCTAAAGATAAACAATATTTGATAACAGACTTTA
GATATATTGATCAAGCAACTAAGCAGGCGCCAAATTATGAAATTATTAATCGTAAATCTACTATTATTGGTGAGATTAAA
GAATTGCTACACCAAGAAAATTTTGAAAATGTAGGTTTTGAGGGGCATCATGTAAGTTATGATACATACCTTGAATTAAA
TAAAAGCCGTATATCATTAATAAGCATTTCTAATACTGTAGATAAAATTAGAGACGTCAAAGATGCTGACGAAATTGCTT
TAATTCAAAAAGCAGCTAATATTGTTGATGAAACATATGAATATATTTTAACTGTTGTAAAAGCAGGCATGACTGAAAAA
GAATTAAAGGCAATATTAGAAAGCAAAATGCTAGAATTAGGAGCAGATGGACCATCATTCGATACGATTGTAGCATCTGG
TCATAGAGGTGCATTACCACATGGTGTTGCAAGTGATAAAATTATTGAAAAAGGCGACATGATTACATTAGATTTTGGCG
CGTATTATAACGGCTATTGTTCAGATATTACTAGAACATTTGCTATTGGAGAACCAGATCCTAAACTGAAAGAAATATAT
CAAATAGTACTTGAATCTCAAATGAAAGCAATTAATGAGATTAGACCTGGCATGACTGGTGCAGAAGCTGATGCCATTTC
AAGAAACTATTTAGAGTCAAAAGGGTATGGAAAAGAATTTGGACATTCACTAGGACATGGTATTGGTTTAGAAATCCATG
AAGGGCCAATGCTGGCTCGTACGATACAAGATAAACTTCAAGTTAACAACTGTGTTACAGTAGAACCTGGTGTTTATATA
GAAGGTTTGGGCGGTATAAGAATAGAAGATGATATTTTAATTACAGAAAATGGTTGTCAAGTCTTTACTAAATGCACAAA
AGACCTTATAGTTTTAACATAA

Upstream 100 bases:

>100_bases
ATCTCCCTAAAATCAATATCTATTATTTTTTATCCTTATTATGATATTATTTTAATGTATAAAGTTGAAATGCACAAACG
TTTCACTAGGAGGTAATAAG

Downstream 100 bases:

>100_bases
GCGTGTAAAATGAGGAGGAAACTGAATGATTTCGGTTAATGATTTTAAAACAGGTTTAACAATTTCTGTTGATAACGCTA
TTTGGAAAGTTATAGACTTC

Product: proline dipeptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 353; Mature: 352

Protein sequence:

>353_residues
MSRITQVHRILEQKHLDAIIILSDYNRRYLSGFTGTSGALIISKDKQYLITDFRYIDQATKQAPNYEIINRKSTIIGEIK
ELLHQENFENVGFEGHHVSYDTYLELNKSRISLISISNTVDKIRDVKDADEIALIQKAANIVDETYEYILTVVKAGMTEK
ELKAILESKMLELGADGPSFDTIVASGHRGALPHGVASDKIIEKGDMITLDFGAYYNGYCSDITRTFAIGEPDPKLKEIY
QIVLESQMKAINEIRPGMTGAEADAISRNYLESKGYGKEFGHSLGHGIGLEIHEGPMLARTIQDKLQVNNCVTVEPGVYI
EGLGGIRIEDDILITENGCQVFTKCTKDLIVLT

Sequences:

>Translated_353_residues
MSRITQVHRILEQKHLDAIIILSDYNRRYLSGFTGTSGALIISKDKQYLITDFRYIDQATKQAPNYEIINRKSTIIGEIK
ELLHQENFENVGFEGHHVSYDTYLELNKSRISLISISNTVDKIRDVKDADEIALIQKAANIVDETYEYILTVVKAGMTEK
ELKAILESKMLELGADGPSFDTIVASGHRGALPHGVASDKIIEKGDMITLDFGAYYNGYCSDITRTFAIGEPDPKLKEIY
QIVLESQMKAINEIRPGMTGAEADAISRNYLESKGYGKEFGHSLGHGIGLEIHEGPMLARTIQDKLQVNNCVTVEPGVYI
EGLGGIRIEDDILITENGCQVFTKCTKDLIVLT
>Mature_352_residues
SRITQVHRILEQKHLDAIIILSDYNRRYLSGFTGTSGALIISKDKQYLITDFRYIDQATKQAPNYEIINRKSTIIGEIKE
LLHQENFENVGFEGHHVSYDTYLELNKSRISLISISNTVDKIRDVKDADEIALIQKAANIVDETYEYILTVVKAGMTEKE
LKAILESKMLELGADGPSFDTIVASGHRGALPHGVASDKIIEKGDMITLDFGAYYNGYCSDITRTFAIGEPDPKLKEIYQ
IVLESQMKAINEIRPGMTGAEADAISRNYLESKGYGKEFGHSLGHGIGLEIHEGPMLARTIQDKLQVNNCVTVEPGVYIE
GLGGIRIEDDILITENGCQVFTKCTKDLIVLT

Specific function: Unknown

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family [H]

Homologues:

Organism=Homo sapiens, GI11559925, Length=272, Percent_Identity=27.9411764705882, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI149589008, Length=302, Percent_Identity=26.8211920529801, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI260593665, Length=302, Percent_Identity=26.8211920529801, Blast_Score=89, Evalue=8e-18,
Organism=Homo sapiens, GI93141226, Length=168, Percent_Identity=35.7142857142857, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI264681563, Length=165, Percent_Identity=33.3333333333333, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI164420681, Length=172, Percent_Identity=25, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI40385867, Length=248, Percent_Identity=24.1935483870968, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI264681565, Length=162, Percent_Identity=32.7160493827161, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1788728, Length=358, Percent_Identity=37.9888268156425, Blast_Score=265, Evalue=4e-72,
Organism=Escherichia coli, GI1789275, Length=261, Percent_Identity=30.6513409961686, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1786364, Length=251, Percent_Identity=25.0996015936255, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1790282, Length=321, Percent_Identity=21.8068535825545, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17508215, Length=285, Percent_Identity=25.6140350877193, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17509539, Length=163, Percent_Identity=33.1288343558282, Blast_Score=77, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6321118, Length=289, Percent_Identity=27.3356401384083, Blast_Score=101, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6320922, Length=246, Percent_Identity=26.8292682926829, Blast_Score=90, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6322999, Length=175, Percent_Identity=35.4285714285714, Blast_Score=85, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6323273, Length=242, Percent_Identity=24.7933884297521, Blast_Score=63, Evalue=8e-11,
Organism=Drosophila melanogaster, GI19920384, Length=281, Percent_Identity=28.8256227758007, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI21357079, Length=288, Percent_Identity=24.3055555555556, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI21355531, Length=245, Percent_Identity=23.265306122449, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI17137632, Length=166, Percent_Identity=35.5421686746988, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 39338; Mature: 39207

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS00491 PROLINE_PEPTIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRITQVHRILEQKHLDAIIILSDYNRRYLSGFTGTSGALIISKDKQYLITDFRYIDQAT
CCHHHHHHHHHHHHCCCEEEEEECCCCHHHCCCCCCCCEEEEECCCCEEHHHHHHHHHHH
KQAPNYEIINRKSTIIGEIKELLHQENFENVGFEGHHVSYDTYLELNKSRISLISISNTV
HCCCCEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCEECCHHEEEECCCEEEEEEEHHHH
DKIRDVKDADEIALIQKAANIVDETYEYILTVVKAGMTEKELKAILESKMLELGADGPSF
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCC
DTIVASGHRGALPHGVASDKIIEKGDMITLDFGAYYNGYCSDITRTFAIGEPDPKLKEIY
CCEEECCCCCCCCCCCCCCCEECCCCEEEEECCCCCCCHHHHHHHHEECCCCCHHHHHHH
QIVLESQMKAINEIRPGMTGAEADAISRNYLESKGYGKEFGHSLGHGIGLEIHEGPMLAR
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHCCCCCEEECCCCHHHH
TIQDKLQVNNCVTVEPGVYIEGLGGIRIEDDILITENGCQVFTKCTKDLIVLT
HHHHHHHCCCEEEECCCEEEECCCCEEEECCEEEECCCHHHHHHHCCCEEEEC
>Mature Secondary Structure 
SRITQVHRILEQKHLDAIIILSDYNRRYLSGFTGTSGALIISKDKQYLITDFRYIDQAT
CHHHHHHHHHHHHCCCEEEEEECCCCHHHCCCCCCCCEEEEECCCCEEHHHHHHHHHHH
KQAPNYEIINRKSTIIGEIKELLHQENFENVGFEGHHVSYDTYLELNKSRISLISISNTV
HCCCCEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCEECCHHEEEECCCEEEEEEEHHHH
DKIRDVKDADEIALIQKAANIVDETYEYILTVVKAGMTEKELKAILESKMLELGADGPSF
HHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCC
DTIVASGHRGALPHGVASDKIIEKGDMITLDFGAYYNGYCSDITRTFAIGEPDPKLKEIY
CCEEECCCCCCCCCCCCCCCEECCCCEEEEECCCCCCCHHHHHHHHEECCCCCHHHHHHH
QIVLESQMKAINEIRPGMTGAEADAISRNYLESKGYGKEFGHSLGHGIGLEIHEGPMLAR
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHCCCCCEEECCCCHHHH
TIQDKLQVNNCVTVEPGVYIEGLGGIRIEDDILITENGCQVFTKCTKDLIVLT
HHHHHHHCCCEEEECCCEEEECCCCEEEECCEEEECCCHHHHHHHCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]