Click here to switch to the map view.

The map label for this gene is efp

Identifier: 57651923

GI number: 57651923

Start: 1621582

End: 1622139

Strand: Reverse

Name: efp

Synonym: SACOL1587

Alternate gene names: 57651923

Gene position: 1622139-1621582 (Counterclockwise)

Preceding gene: 57651924

Following gene: 57651922

Centisome position: 57.74

GC content: 33.15

Gene sequence:

>558_bases
ATGATTTCGGTTAATGATTTTAAAACAGGTTTAACAATTTCTGTTGATAACGCTATTTGGAAAGTTATAGACTTCCAACA
TGTAAAGCCTGGTAAAGGTTCAGCATTCGTTCGTTCAAAATTACGTAATTTAAGAACTGGTGCAATTCAAGAGAAAACGT
TTAGAGCTGGTGAAAAAGTTGAACCAGCAATGATTGAAAATCGTCGCATGCAATATTTATATGCTGACGGAGATAATCAT
GTATTTATGGATAATGAAAGCTTTGAACAAACAGAACTTTCAAGTGATTACTTAAAAGAAGAATTGAATTACTTAAAAGA
AGGTATGGAAGTACAAATTCAAACATACGAAGGTGAAACTATCGGTGTTGAATTACCTAAAACTGTTGAATTAACAGTAA
CTGAAACAGAACCTGGTATTAAAGGTGATACTGCAACTGGTGCCACTAAATCGGCAACTGTTGAAACTGGTTATACATTA
AATGTACCTTTATTTGTAAACGAAGGTGACGTTTTAATTATCAACACTGGTGATGGAAGCTACATTTCAAGAGGATAA

Upstream 100 bases:

>100_bases
GATGATATTTTAATTACAGAAAATGGTTGTCAAGTCTTTACTAAATGCACAAAAGACCTTATAGTTTTAACATAAGCGTG
TAAAATGAGGAGGAAACTGA

Downstream 100 bases:

>100_bases
TCTCTAATTTGTTAACAAATAGCTTGTATTCACTATACTGATTTAACGTAAGATATTCTAAATAAGTCTCATAAAGCTAT
TGCCTAAAATGATTATAGGT

Product: elongation factor P

Products: NA

Alternate protein names: EF-P

Number of amino acids: Translated: 185; Mature: 185

Protein sequence:

>185_residues
MISVNDFKTGLTISVDNAIWKVIDFQHVKPGKGSAFVRSKLRNLRTGAIQEKTFRAGEKVEPAMIENRRMQYLYADGDNH
VFMDNESFEQTELSSDYLKEELNYLKEGMEVQIQTYEGETIGVELPKTVELTVTETEPGIKGDTATGATKSATVETGYTL
NVPLFVNEGDVLIINTGDGSYISRG

Sequences:

>Translated_185_residues
MISVNDFKTGLTISVDNAIWKVIDFQHVKPGKGSAFVRSKLRNLRTGAIQEKTFRAGEKVEPAMIENRRMQYLYADGDNH
VFMDNESFEQTELSSDYLKEELNYLKEGMEVQIQTYEGETIGVELPKTVELTVTETEPGIKGDTATGATKSATVETGYTL
NVPLFVNEGDVLIINTGDGSYISRG
>Mature_185_residues
MISVNDFKTGLTISVDNAIWKVIDFQHVKPGKGSAFVRSKLRNLRTGAIQEKTFRAGEKVEPAMIENRRMQYLYADGDNH
VFMDNESFEQTELSSDYLKEELNYLKEGMEVQIQTYEGETIGVELPKTVELTVTETEPGIKGDTATGATKSATVETGYTL
NVPLFVNEGDVLIINTGDGSYISRG

Specific function: Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing t

COG id: COG0231

COG function: function code J; Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the elongation factor P family

Homologues:

Organism=Escherichia coli, GI1790590, Length=180, Percent_Identity=41.6666666666667, Blast_Score=143, Evalue=6e-36,
Organism=Escherichia coli, GI87082061, Length=189, Percent_Identity=30.6878306878307, Blast_Score=110, Evalue=8e-26,

Paralogues:

None

Copy number: 1600 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): EFP_STAA1 (A7X2Q9)

Other databases:

- EMBL:   AP009324
- RefSeq:   YP_001442106.1
- ProteinModelPortal:   A7X2Q9
- SMR:   A7X2Q9
- STRING:   A7X2Q9
- EnsemblBacteria:   EBSTAT00000004275
- GeneID:   5561495
- GenomeReviews:   AP009324_GR
- KEGG:   saw:SAHV_1516
- eggNOG:   COG0231
- GeneTree:   EBGT00050000024489
- HOGENOM:   HBG303311
- OMA:   MISSNDF
- ProtClustDB:   PRK00529
- BioCyc:   SAUR418127:SAHV_1516-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00141
- InterPro:   IPR015365
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR020599
- InterPro:   IPR013185
- InterPro:   IPR001059
- InterPro:   IPR013852
- InterPro:   IPR011768
- InterPro:   IPR014722
- InterPro:   IPR008991
- Gene3D:   G3DSA:2.40.50.140
- Gene3D:   G3DSA:2.30.30.30
- PIRSF:   PIRSF005901
- SMART:   SM00841
- TIGRFAMs:   TIGR00038

Pfam domain/function: PF01132 EFP; PF08207 EFP_N; PF09285 Elong-fact-P_C; SSF50249 Nucleic_acid_OB; SSF50104 Transl_SH3_like

EC number: NA

Molecular weight: Translated: 20554; Mature: 20554

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: PS01275 EFP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISVNDFKTGLTISVDNAIWKVIDFQHVKPGKGSAFVRSKLRNLRTGAIQEKTFRAGEKV
CCCCCCCCCCEEEEECCCEEEEEEEEECCCCCCHHHHHHHHHHHCCCCCCHHHHCCCCCC
EPAMIENRRMQYLYADGDNHVFMDNESFEQTELSSDYLKEELNYLKEGMEVQIQTYEGET
CCHHHCCCEEEEEEECCCCEEEECCCCCCHHHCCHHHHHHHHHHHHCCCEEEEEEECCCE
IGVELPKTVELTVTETEPGIKGDTATGATKSATVETGYTLNVPLFVNEGDVLIINTGDGS
EEEECCCEEEEEEEECCCCCCCCCCCCCCCCEEEECCEEEEEEEEECCCCEEEEECCCCC
YISRG
EECCC
>Mature Secondary Structure
MISVNDFKTGLTISVDNAIWKVIDFQHVKPGKGSAFVRSKLRNLRTGAIQEKTFRAGEKV
CCCCCCCCCCEEEEECCCEEEEEEEEECCCCCCHHHHHHHHHHHCCCCCCHHHHCCCCCC
EPAMIENRRMQYLYADGDNHVFMDNESFEQTELSSDYLKEELNYLKEGMEVQIQTYEGET
CCHHHCCCEEEEEEECCCCEEEECCCCCCHHHCCHHHHHHHHHHHHCCCEEEEEEECCCE
IGVELPKTVELTVTETEPGIKGDTATGATKSATVETGYTLNVPLFVNEGDVLIINTGDGS
EEEECCCEEEEEEEECCCCCCCCCCCCCCCCEEEECCEEEEEEEEECCCCEEEEECCCCC
YISRG
EECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA