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The map label for this gene is hepT [H]

Identifier: 57650425

GI number: 57650425

Start: 1549577

End: 1550536

Strand: Reverse

Name: hepT [H]

Synonym: SACOL1510

Alternate gene names: 57650425

Gene position: 1550536-1549577 (Counterclockwise)

Preceding gene: 57650426

Following gene: 57650424

Centisome position: 55.19

GC content: 34.69

Gene sequence:

>960_bases
GTGGCAAAGTTAAACATGAACAATGAAATTAAGAAAGTGGAACAACGACTTGAAAAGGCAATAAAAAGTAAAGATTCTGT
ATTAGAACAGGCATCATTACACTTATTGTCTTCTGGTGGTAAAAGAGTACGCCCAGCATTTGTTATTCTGAGTAGCCAAT
TTGGCAAAGATGAACAAACGTCTGAACAAACGTATCAAGTTGCAGTCGCATTAGAGTTAATTCATATGGCAACACTTGTT
CATGATGACGTTATTGATAAAAGCGACAAGCGTCGAGGCAAGTTAACCATATCAAAGAAATGGGATCAGACAACTGCTAT
TTTAACTGGGAATTTTTTATTGGCATTAGGACTTGAACACTTAATGGCCGTTAAAGATAATCGTGTACATCAATTGATAT
CTGAATCTATCGTTGATGTTTGTAGAGGGGAACTTTTCCAATTTCAAGACCAATTTAACAGTCAACAGACAATTATTAAT
TATTTACGACGTATCAATCGCAAAACAGCACTGTTAATTCAAATATCAACTGAAGTTGGTGCAATTACTTCTCAATCTGA
TAAAGAGACTGTACGAAAATTGAAAATGATTGGTCATTATATAGGTATGAGCTTCCAAATCATTGATGATGTATTAGACT
TCACAAGTACCGAAAAGAAATTAGGTAAGCCGGTCGGAAGTGATTTGCTTAATGGTCATATTACGTTACCGATTTTATTA
GAAATGCGTAAAAATCCAGACTTCAAATTGAAAATCGAACAGTTACGTCGTGATAGTGAACGCAAAGAATTTGAAGAATG
TATCCAAATCATTAGAAAATCTGACAGCATCGATGAGGCTAAGGCAGTAAGTTCGAAGTATTTAAGTAAAGCTTTGAATT
TGATTTCTGAGTTACCAGATGGACATCCGAAATCACTACTTTTAAGTTTGACGAAAAAAATGGGTTCAAGAAACACGTAG

Upstream 100 bases:

>100_bases
GAAGCAGGTTTCATAAATGTAAGAGTACGTAGTTTTACAGGGGGCGTTGCTGCAATGCACCTTGGCTATAAAGAAAAAGA
TAATACCAAAGGTGATTAAC

Downstream 100 bases:

>100_bases
TATTTATGAAAAGTATTGAAAGCGCTTTACCAACCTGTTAATATATAATAGTAATATACATAAACCTATTAAACACAGGG
GGATACATAAAGTGGAACGT

Product: polyprenyl synthetase

Products: NA

Alternate protein names: HEPPP synthase subunit 2; Spore germination protein C3 [H]

Number of amino acids: Translated: 319; Mature: 318

Protein sequence:

>319_residues
MAKLNMNNEIKKVEQRLEKAIKSKDSVLEQASLHLLSSGGKRVRPAFVILSSQFGKDEQTSEQTYQVAVALELIHMATLV
HDDVIDKSDKRRGKLTISKKWDQTTAILTGNFLLALGLEHLMAVKDNRVHQLISESIVDVCRGELFQFQDQFNSQQTIIN
YLRRINRKTALLIQISTEVGAITSQSDKETVRKLKMIGHYIGMSFQIIDDVLDFTSTEKKLGKPVGSDLLNGHITLPILL
EMRKNPDFKLKIEQLRRDSERKEFEECIQIIRKSDSIDEAKAVSSKYLSKALNLISELPDGHPKSLLLSLTKKMGSRNT

Sequences:

>Translated_319_residues
MAKLNMNNEIKKVEQRLEKAIKSKDSVLEQASLHLLSSGGKRVRPAFVILSSQFGKDEQTSEQTYQVAVALELIHMATLV
HDDVIDKSDKRRGKLTISKKWDQTTAILTGNFLLALGLEHLMAVKDNRVHQLISESIVDVCRGELFQFQDQFNSQQTIIN
YLRRINRKTALLIQISTEVGAITSQSDKETVRKLKMIGHYIGMSFQIIDDVLDFTSTEKKLGKPVGSDLLNGHITLPILL
EMRKNPDFKLKIEQLRRDSERKEFEECIQIIRKSDSIDEAKAVSSKYLSKALNLISELPDGHPKSLLLSLTKKMGSRNT
>Mature_318_residues
AKLNMNNEIKKVEQRLEKAIKSKDSVLEQASLHLLSSGGKRVRPAFVILSSQFGKDEQTSEQTYQVAVALELIHMATLVH
DDVIDKSDKRRGKLTISKKWDQTTAILTGNFLLALGLEHLMAVKDNRVHQLISESIVDVCRGELFQFQDQFNSQQTIINY
LRRINRKTALLIQISTEVGAITSQSDKETVRKLKMIGHYIGMSFQIIDDVLDFTSTEKKLGKPVGSDLLNGHITLPILLE
MRKNPDFKLKIEQLRRDSERKEFEECIQIIRKSDSIDEAKAVSSKYLSKALNLISELPDGHPKSLLLSLTKKMGSRNT

Specific function: Supplies heptaprenyl diphosphate, the precursor for the side chain of the isoprenoid quinone menaquinone-7 (MQ-7) [H]

COG id: COG0142

COG function: function code H; Geranylgeranyl pyrophosphate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FPP/GGPP synthase family [H]

Homologues:

Organism=Homo sapiens, GI50659086, Length=315, Percent_Identity=30.1587301587302, Blast_Score=148, Evalue=6e-36,
Organism=Escherichia coli, GI1789578, Length=308, Percent_Identity=29.2207792207792, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI1786623, Length=223, Percent_Identity=32.7354260089686, Blast_Score=78, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17505681, Length=243, Percent_Identity=29.2181069958848, Blast_Score=128, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6319475, Length=309, Percent_Identity=29.7734627831715, Blast_Score=126, Evalue=4e-30,
Organism=Drosophila melanogaster, GI24651612, Length=277, Percent_Identity=28.8808664259928, Blast_Score=151, Evalue=7e-37,
Organism=Drosophila melanogaster, GI281365769, Length=267, Percent_Identity=24.3445692883895, Blast_Score=64, Evalue=1e-10,
Organism=Drosophila melanogaster, GI24660002, Length=267, Percent_Identity=24.3445692883895, Blast_Score=64, Evalue=1e-10,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014119
- InterPro:   IPR000092
- InterPro:   IPR017446
- InterPro:   IPR008949 [H]

Pfam domain/function: PF00348 polyprenyl_synt [H]

EC number: =2.5.1.30 [H]

Molecular weight: Translated: 36143; Mature: 36012

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: PS00723 POLYPRENYL_SYNTHET_1 ; PS00444 POLYPRENYL_SYNTHET_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKLNMNNEIKKVEQRLEKAIKSKDSVLEQASLHLLSSGGKRVRPAFVILSSQFGKDEQT
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHEEEEECCCCCCCCH
SEQTYQVAVALELIHMATLVHDDVIDKSDKRRGKLTISKKWDQTTAILTGNFLLALGLEH
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCHHHHHCCHHHHHHHHHH
LMAVKDNRVHQLISESIVDVCRGELFQFQDQFNSQQTIINYLRRINRKTALLIQISTEVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEEEEECCCC
AITSQSDKETVRKLKMIGHYIGMSFQIIDDVLDFTSTEKKLGKPVGSDLLNGHITLPILL
CCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHCCCCCHHHHCCCCHHHHHE
EMRKNPDFKLKIEQLRRDSERKEFEECIQIIRKSDSIDEAKAVSSKYLSKALNLISELPD
EECCCCCCEEEHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCC
GHPKSLLLSLTKKMGSRNT
CCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AKLNMNNEIKKVEQRLEKAIKSKDSVLEQASLHLLSSGGKRVRPAFVILSSQFGKDEQT
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHEEEEECCCCCCCCH
SEQTYQVAVALELIHMATLVHDDVIDKSDKRRGKLTISKKWDQTTAILTGNFLLALGLEH
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCHHHHHCCHHHHHHHHHH
LMAVKDNRVHQLISESIVDVCRGELFQFQDQFNSQQTIINYLRRINRKTALLIQISTEVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCEEEEEEEECCCC
AITSQSDKETVRKLKMIGHYIGMSFQIIDDVLDFTSTEKKLGKPVGSDLLNGHITLPILL
CCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHCCCCCHHHHCCCCHHHHHE
EMRKNPDFKLKIEQLRRDSERKEFEECIQIIRKSDSIDEAKAVSSKYLSKALNLISELPD
EECCCCCCEEEHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCC
GHPKSLLLSLTKKMGSRNT
CCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 2121900; 9720033 [H]