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The map label for this gene is trpB [H]

Identifier: 57650376

GI number: 57650376

Start: 1418592

End: 1419806

Strand: Direct

Name: trpB [H]

Synonym: SACOL1408

Alternate gene names: 57650376

Gene position: 1418592-1419806 (Clockwise)

Preceding gene: 57650375

Following gene: 57650377

Centisome position: 50.49

GC content: 37.7

Gene sequence:

>1215_bases
ATGAATAAACAAATACAAACAGAAGCAGATGAATTAGGTTTCTTTGGTGAATATGGAGGGCAATATGTTCCAGAAACATT
AATGCCAGCAATTATTGAGTTGAAAAAAGCTTATAAAGAGGCAAAAGCAGACCCAGAGTTTCAAAGAGAACTGGAATACT
ATTTATCAGAGTATGTAGGACGCGCGACACCACTTACATATGCTGCATCATATACTGAAAGCCTAGGTGGCGCTAAAATA
TATTTGAAACGAGAGGATCTAAATCATACAGGCGCCCATAAAATTAATAATGCGTTAGGTCAAGCGTTGCTTGCTAAAAG
AATGGGCAAGAAGAAGCTTGTTGCTGAAACTGGTGCGGGTCAACATGGTGTAGCTAGTGCTACGGTTGCTGCATTATTTG
ATATGGAACTTGTTGTCTTTATGGGAAGTGAAGATATTAAAAGACAACAACTTAATGTATTTAGAATGGAATTACTTGGT
GCAAAGGTTGTGGCAGTTGAAGATGGTCAAGGGACTTTATCGGATGCAGTTAATAAAGCATTGCAATATTGGGTAAGTCA
TGTAGATGATACACATTATTTATTAGGTTCTGCATTAGGTCCAGACCCGTTCCCAACGATTGTTAGAGATTTTCAGAGTG
TGATTGGTAAAGAAATAAAATCACAGATATTGAAGAAAGAAGGTCGACTTCCGGATGCAATTGTAGCATGTATCGGTGGT
GGCTCAAATGCAATCGGTACATTTTATCCATTTATTAAAGATGATGTTGCATTATACGGTGTTGAAGCCGCAGGTCAAGG
CGATGATACTGATAAACATGCACTTGCAATTGGCAAAGGATCACCTGGCGTATTACATGGTACTAAAATGTATTTAATTC
AAGATGAAGATGGGCAAGTGCAACTAGCACATTCTATTTCAGCAGGACTTGATTATCCTGGTATTGGACCAGAACATTCT
TATTACCACGACATTGGTAGAGTAACTTTTGAAAATGCTAGTGATACACAAGCAATGAATGCTTTAATCAACTTTACAAA
ACATGAAGGTATTATACCTGCAATTGAAAGTGCACATGCACTGAGTTATGTTGAAAGACTAGCGCCTACGATGTCGAAAG
AAGATATTATTGTAGTAACTATTTCTGGACGTGGCGATAAAGATATGGAAACAATTAGACAATATATGGTAGAGCGAGGT
CTTGCAAATGACTAA

Upstream 100 bases:

>100_bases
CATCAAGGTTATGATCTTGCATCAGGTATAGAAGTAAATGGGCGAAAAGATATAGAAAAAATGACAGCAATTGTAAATAT
TGTGAAAGGAGATAGAGACA

Downstream 100 bases:

>100_bases
ATTATTTATACCTTATATTATGGGCAATAAAGATTTGATTGAAAATGCAACATTGTTGAGTGAAAATGGTGCAGATATAA
TTGAAATTGGAGTACCTTTC

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MNKQIQTEADELGFFGEYGGQYVPETLMPAIIELKKAYKEAKADPEFQRELEYYLSEYVGRATPLTYAASYTESLGGAKI
YLKREDLNHTGAHKINNALGQALLAKRMGKKKLVAETGAGQHGVASATVAALFDMELVVFMGSEDIKRQQLNVFRMELLG
AKVVAVEDGQGTLSDAVNKALQYWVSHVDDTHYLLGSALGPDPFPTIVRDFQSVIGKEIKSQILKKEGRLPDAIVACIGG
GSNAIGTFYPFIKDDVALYGVEAAGQGDDTDKHALAIGKGSPGVLHGTKMYLIQDEDGQVQLAHSISAGLDYPGIGPEHS
YYHDIGRVTFENASDTQAMNALINFTKHEGIIPAIESAHALSYVERLAPTMSKEDIIVVTISGRGDKDMETIRQYMVERG
LAND

Sequences:

>Translated_404_residues
MNKQIQTEADELGFFGEYGGQYVPETLMPAIIELKKAYKEAKADPEFQRELEYYLSEYVGRATPLTYAASYTESLGGAKI
YLKREDLNHTGAHKINNALGQALLAKRMGKKKLVAETGAGQHGVASATVAALFDMELVVFMGSEDIKRQQLNVFRMELLG
AKVVAVEDGQGTLSDAVNKALQYWVSHVDDTHYLLGSALGPDPFPTIVRDFQSVIGKEIKSQILKKEGRLPDAIVACIGG
GSNAIGTFYPFIKDDVALYGVEAAGQGDDTDKHALAIGKGSPGVLHGTKMYLIQDEDGQVQLAHSISAGLDYPGIGPEHS
YYHDIGRVTFENASDTQAMNALINFTKHEGIIPAIESAHALSYVERLAPTMSKEDIIVVTISGRGDKDMETIRQYMVERG
LAND
>Mature_404_residues
MNKQIQTEADELGFFGEYGGQYVPETLMPAIIELKKAYKEAKADPEFQRELEYYLSEYVGRATPLTYAASYTESLGGAKI
YLKREDLNHTGAHKINNALGQALLAKRMGKKKLVAETGAGQHGVASATVAALFDMELVVFMGSEDIKRQQLNVFRMELLG
AKVVAVEDGQGTLSDAVNKALQYWVSHVDDTHYLLGSALGPDPFPTIVRDFQSVIGKEIKSQILKKEGRLPDAIVACIGG
GSNAIGTFYPFIKDDVALYGVEAAGQGDDTDKHALAIGKGSPGVLHGTKMYLIQDEDGQVQLAHSISAGLDYPGIGPEHS
YYHDIGRVTFENASDTQAMNALINFTKHEGIIPAIESAHALSYVERLAPTMSKEDIIVVTISGRGDKDMETIRQYMVERG
LAND

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine [H]

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family [H]

Homologues:

Organism=Escherichia coli, GI1787515, Length=389, Percent_Identity=50.1285347043702, Blast_Score=407, Evalue=1e-115,
Organism=Saccharomyces cerevisiae, GI6321412, Length=388, Percent_Identity=54.1237113402062, Blast_Score=432, Evalue=1e-122,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 43965; Mature: 43965

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKQIQTEADELGFFGEYGGQYVPETLMPAIIELKKAYKEAKADPEFQRELEYYLSEYVG
CCCCCCCCHHHCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCC
RATPLTYAASYTESLGGAKIYLKREDLNHTGAHKINNALGQALLAKRMGKKKLVAETGAG
CCCCHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHCCCC
QHGVASATVAALFDMELVVFMGSEDIKRQQLNVFRMELLGAKVVAVEDGQGTLSDAVNKA
CCCHHHHHHHHHHHHEEEEEECCHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHH
LQYWVSHVDDTHYLLGSALGPDPFPTIVRDFQSVIGKEIKSQILKKEGRLPDAIVACIGG
HHHHHHHCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHEEECC
GSNAIGTFYPFIKDDVALYGVEAAGQGDDTDKHALAIGKGSPGVLHGTKMYLIQDEDGQV
CCCCCHHHHHHHHCCEEEEEEECCCCCCCCCCCEEEECCCCCCEEECCEEEEEECCCCCE
QLAHSISAGLDYPGIGPEHSYYHDIGRVTFENASDTQAMNALINFTKHEGIIPAIESAHA
EEEEHHHCCCCCCCCCCCCHHHHHHCCEEECCCCHHHHHHHHHHHHHCCCCCHHHHHHHH
LSYVERLAPTMSKEDIIVVTISGRGDKDMETIRQYMVERGLAND
HHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MNKQIQTEADELGFFGEYGGQYVPETLMPAIIELKKAYKEAKADPEFQRELEYYLSEYVG
CCCCCCCCHHHCCCCHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCC
RATPLTYAASYTESLGGAKIYLKREDLNHTGAHKINNALGQALLAKRMGKKKLVAETGAG
CCCCHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHCCCC
QHGVASATVAALFDMELVVFMGSEDIKRQQLNVFRMELLGAKVVAVEDGQGTLSDAVNKA
CCCHHHHHHHHHHHHEEEEEECCHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHHH
LQYWVSHVDDTHYLLGSALGPDPFPTIVRDFQSVIGKEIKSQILKKEGRLPDAIVACIGG
HHHHHHHCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHEEECC
GSNAIGTFYPFIKDDVALYGVEAAGQGDDTDKHALAIGKGSPGVLHGTKMYLIQDEDGQV
CCCCCHHHHHHHHCCEEEEEEECCCCCCCCCCCEEEECCCCCCEEECCEEEEEECCCCCE
QLAHSISAGLDYPGIGPEHSYYHDIGRVTFENASDTQAMNALINFTKHEGIIPAIESAHA
EEEEHHHCCCCCCCCCCCCHHHHHHCCEEECCCCHHHHHHHHHHHHHCCCCCHHHHHHHH
LSYVERLAPTMSKEDIIVVTISGRGDKDMETIRQYMVERGLAND
HHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA