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The map label for this gene is trpF [H]

Identifier: 57650375

GI number: 57650375

Start: 1417964

End: 1418599

Strand: Direct

Name: trpF [H]

Synonym: SACOL1407

Alternate gene names: 57650375

Gene position: 1417964-1418599 (Clockwise)

Preceding gene: 57650374

Following gene: 57650376

Centisome position: 50.47

GC content: 31.6

Gene sequence:

>636_bases
ATGATGAAATTGAAATTTTGTGGCTTTACATCAATAAAGGATGTTACAGCGGCCAGTCAATTACCTATTGATGCGATAGG
TTTCATCCATTATGAAAAAAGTAAAAGGCATCAAACAATTACCCAAATAAAAAAGTTAGCGTCTGCTGTTCCAAATCATA
TCGATAAAGTATGTGTCATGGTAAATCCTGATTTAACAACAATTGAACACGTATTAAGCAATACGTCAATTAACACAATA
CAGTTACACGGCACAGAATCTATTGATTTTATACAGGAAATTAAAAAGAAATATTCAAGCATTAAAATCACTAAAGCTTT
AGCTGCAGATGAAAACATAATCCAAAACATAAATAAATATAAAGGGTTCGTAGATTTATTTATTATCGACACACCCTCAG
TGTCGTATGGTGGTACCGGTCAAACATATGACTGGACTATTTTGAAGCACATAAAAGACATACCTTATTTGATAGCAGGA
GGCATTAACTCTGAAAATATTCAAACAGTTAATCAACTTAAATTATCACATCAAGGTTATGATCTTGCATCAGGTATAGA
AGTAAATGGGCGAAAAGATATAGAAAAAATGACAGCAATTGTAAATATTGTGAAAGGAGATAGAGACAATGAATAA

Upstream 100 bases:

>100_bases
TGCATAGTGGTATCGATGGCTTACTAATAGGTGAGGCGCTTATGCGTTGTGACAATCTATCTGAATTTTTACCACAACTG
AAAATGCAAAAGGTGAAGTC

Downstream 100 bases:

>100_bases
ACAAATACAAACAGAAGCAGATGAATTAGGTTTCTTTGGTGAATATGGAGGGCAATATGTTCCAGAAACATTAATGCCAG
CAATTATTGAGTTGAAAAAA

Product: N-(5'-phosphoribosyl)anthranilate isomerase

Products: NA

Alternate protein names: PRAI [H]

Number of amino acids: Translated: 211; Mature: 211

Protein sequence:

>211_residues
MMKLKFCGFTSIKDVTAASQLPIDAIGFIHYEKSKRHQTITQIKKLASAVPNHIDKVCVMVNPDLTTIEHVLSNTSINTI
QLHGTESIDFIQEIKKKYSSIKITKALAADENIIQNINKYKGFVDLFIIDTPSVSYGGTGQTYDWTILKHIKDIPYLIAG
GINSENIQTVNQLKLSHQGYDLASGIEVNGRKDIEKMTAIVNIVKGDRDNE

Sequences:

>Translated_211_residues
MMKLKFCGFTSIKDVTAASQLPIDAIGFIHYEKSKRHQTITQIKKLASAVPNHIDKVCVMVNPDLTTIEHVLSNTSINTI
QLHGTESIDFIQEIKKKYSSIKITKALAADENIIQNINKYKGFVDLFIIDTPSVSYGGTGQTYDWTILKHIKDIPYLIAG
GINSENIQTVNQLKLSHQGYDLASGIEVNGRKDIEKMTAIVNIVKGDRDNE
>Mature_211_residues
MMKLKFCGFTSIKDVTAASQLPIDAIGFIHYEKSKRHQTITQIKKLASAVPNHIDKVCVMVNPDLTTIEHVLSNTSINTI
QLHGTESIDFIQEIKKKYSSIKITKALAADENIIQNINKYKGFVDLFIIDTPSVSYGGTGQTYDWTILKHIKDIPYLIAG
GINSENIQTVNQLKLSHQGYDLASGIEVNGRKDIEKMTAIVNIVKGDRDNE

Specific function: Bifunctional Enzyme That Catalyzes Two Sequential Steps Of Tryptophan Biosynthetic Pathway. The First Reaction Is Catalyzed By The Isomerase, Coded By The Trpf Domain; The Second Reaction Is Catalyzed By The Synthase, Coded By The Trpc Domain. [C]

COG id: COG0135

COG function: function code E; Phosphoribosylanthranilate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpF family [H]

Homologues:

Organism=Escherichia coli, GI87081863, Length=204, Percent_Identity=25.9803921568627, Blast_Score=66, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001240
- InterPro:   IPR011060 [H]

Pfam domain/function: PF00697 PRAI [H]

EC number: =5.3.1.24 [H]

Molecular weight: Translated: 23520; Mature: 23520

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKLKFCGFTSIKDVTAASQLPIDAIGFIHYEKSKRHQTITQIKKLASAVPNHIDKVCVM
CCEEEECCCCCHHHHHHHHCCCCHHHEEEEECCHHHHHHHHHHHHHHHHCCHHHHEEEEE
VNPDLTTIEHVLSNTSINTIQLHGTESIDFIQEIKKKYSSIKITKALAADENIIQNINKY
ECCCHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
KGFVDLFIIDTPSVSYGGTGQTYDWTILKHIKDIPYLIAGGINSENIQTVNQLKLSHQGY
CCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHCCCC
DLASGIEVNGRKDIEKMTAIVNIVKGDRDNE
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MMKLKFCGFTSIKDVTAASQLPIDAIGFIHYEKSKRHQTITQIKKLASAVPNHIDKVCVM
CCEEEECCCCCHHHHHHHHCCCCHHHEEEEECCHHHHHHHHHHHHHHHHCCHHHHEEEEE
VNPDLTTIEHVLSNTSINTIQLHGTESIDFIQEIKKKYSSIKITKALAADENIIQNINKY
ECCCHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
KGFVDLFIIDTPSVSYGGTGQTYDWTILKHIKDIPYLIAGGINSENIQTVNQLKLSHQGY
CCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHCCCC
DLASGIEVNGRKDIEKMTAIVNIVKGDRDNE
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA