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The map label for this gene is aroB [H]

Identifier: 57237833

GI number: 57237833

Start: 1016548

End: 1017603

Strand: Reverse

Name: aroB [H]

Synonym: CJE1088

Alternate gene names: 57237833

Gene position: 1017603-1016548 (Counterclockwise)

Preceding gene: 57237834

Following gene: 57237832

Centisome position: 57.24

GC content: 28.6

Gene sequence:

>1056_bases
ATGCAAGTAGAAGTTAAGTTAAAAGAAAATGCTTATAAGGTTTATATTGATGAACTTGAAGAATTAGAATTTGATAGTAA
GGTTTTTATACTTTCAAATCCTAAGATTTCAGGTCTTCATTTGAAAACATTACTTTCTAAAATTAAGGCAAAAGAAATTT
TTATTGCCACTGTAAAAGATGGTGAAGAATATAAAAATTTAAGCACCATGGAAGAAATTTTAAACCAAATGTTTAATTCT
AAATTGGATAGAAAAAGCGTACTTATAAGTTTTGGTGGTGGCGTGATTAGTGATATGGGCGGATTTGCTGCTAGTATTTA
TCAAAGAGGTATTGATTTTATAAATATTCCTACTACACTTTTAGCTTGTGTTGATGCAGCAGTAGGTGGAAAAACAGGTG
TTAATAATAATTTTGGTAAAAATCTTATTGGCACTTTTTATCAACCTAAAGCTGTATATTGTGAGAGTTTTTTTTTAAAG
ACTTTGAGCTCTAGAGAACTTGCTGCAGGCATGGCTGAATTTATTAAAATGGCAGCAATGTTTGATTATAGTATACTTGA
TTTTATAGAAAAAATTGATGAAAAAAGTTTCTTAAATGCTACTTGTGAGAATGAAATTTTTACTCAAATTATAGCAAAAA
GCATAGAGCTTAAATCAAGGGTTGTTGAACAAGATGAAAAAGAATCAAGGCTTAGAATGCTTTTAAATTATGGTCATACT
TTTGCTCATGTTATAGAAAATTTTACAGATTATAAGCTTTATTTACACGGAGAAGCGGTGGCTATAGGTATGGTTATGGC
AAATCAATTGGCTTTAAATTTAGGGCTTTTGGATAAAATGCAAAGTCAAAGAATAAAAGATATTTTACTTAAATTCGGTT
TGCCAATATCATATAAAATCAACAATGTAGATGAATTTTATGAAGCTTTTTTCATGGATAAAAAAAGCTCTAATAAAAAA
ATCAATTTTGTTCTTGCTAGTCCTTTGGGTAAGGGTTTGATAAAAGGTGATATTTCTAAAGAAGATATAATTGCAACTTT
AAGAGAATTCCAATGA

Upstream 100 bases:

>100_bases
TAGGCATTATTACAAAATGAGACAAAATTACCAACTTTTCATACCAGTAGAATAAATAATTAATTAAATGTGATAAAATA
AATGCAAAAAGAGTAGTTCA

Downstream 100 bases:

>100_bases
AAAAAATTATTATTTTAACCTTTTTTGTTGTTTTTGCTTTTGGTGATGTAAATCGGACTATTATTAATAATATAAATGAG
AAAATTAATACTTTAAATAC

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 351; Mature: 351

Protein sequence:

>351_residues
MQVEVKLKENAYKVYIDELEELEFDSKVFILSNPKISGLHLKTLLSKIKAKEIFIATVKDGEEYKNLSTMEEILNQMFNS
KLDRKSVLISFGGGVISDMGGFAASIYQRGIDFINIPTTLLACVDAAVGGKTGVNNNFGKNLIGTFYQPKAVYCESFFLK
TLSSRELAAGMAEFIKMAAMFDYSILDFIEKIDEKSFLNATCENEIFTQIIAKSIELKSRVVEQDEKESRLRMLLNYGHT
FAHVIENFTDYKLYLHGEAVAIGMVMANQLALNLGLLDKMQSQRIKDILLKFGLPISYKINNVDEFYEAFFMDKKSSNKK
INFVLASPLGKGLIKGDISKEDIIATLREFQ

Sequences:

>Translated_351_residues
MQVEVKLKENAYKVYIDELEELEFDSKVFILSNPKISGLHLKTLLSKIKAKEIFIATVKDGEEYKNLSTMEEILNQMFNS
KLDRKSVLISFGGGVISDMGGFAASIYQRGIDFINIPTTLLACVDAAVGGKTGVNNNFGKNLIGTFYQPKAVYCESFFLK
TLSSRELAAGMAEFIKMAAMFDYSILDFIEKIDEKSFLNATCENEIFTQIIAKSIELKSRVVEQDEKESRLRMLLNYGHT
FAHVIENFTDYKLYLHGEAVAIGMVMANQLALNLGLLDKMQSQRIKDILLKFGLPISYKINNVDEFYEAFFMDKKSSNKK
INFVLASPLGKGLIKGDISKEDIIATLREFQ
>Mature_351_residues
MQVEVKLKENAYKVYIDELEELEFDSKVFILSNPKISGLHLKTLLSKIKAKEIFIATVKDGEEYKNLSTMEEILNQMFNS
KLDRKSVLISFGGGVISDMGGFAASIYQRGIDFINIPTTLLACVDAAVGGKTGVNNNFGKNLIGTFYQPKAVYCESFFLK
TLSSRELAAGMAEFIKMAAMFDYSILDFIEKIDEKSFLNATCENEIFTQIIAKSIELKSRVVEQDEKESRLRMLLNYGHT
FAHVIENFTDYKLYLHGEAVAIGMVMANQLALNLGLLDKMQSQRIKDILLKFGLPISYKINNVDEFYEAFFMDKKSSNKK
INFVLASPLGKGLIKGDISKEDIIATLREFQ

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=362, Percent_Identity=35.0828729281768, Blast_Score=212, Evalue=3e-56,
Organism=Saccharomyces cerevisiae, GI6320332, Length=325, Percent_Identity=34.1538461538462, Blast_Score=179, Evalue=5e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 39597; Mature: 39597

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVEVKLKENAYKVYIDELEELEFDSKVFILSNPKISGLHLKTLLSKIKAKEIFIATVKD
CEEEEEECCCCEEEEEHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHCCCEEEEEEECC
GEEYKNLSTMEEILNQMFNSKLDRKSVLISFGGGVISDMGGFAASIYQRGIDFINIPTTL
CHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCEEEHHHHH
LACVDAAVGGKTGVNNNFGKNLIGTFYQPKAVYCESFFLKTLSSRELAAGMAEFIKMAAM
HHHHHHHCCCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
FDYSILDFIEKIDEKSFLNATCENEIFTQIIAKSIELKSRVVEQDEKESRLRMLLNYGHT
HHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHH
FAHVIENFTDYKLYLHGEAVAIGMVMANQLALNLGLLDKMQSQRIKDILLKFGLPISYKI
HHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
NNVDEFYEAFFMDKKSSNKKINFVLASPLGKGLIKGDISKEDIIATLREFQ
CCHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MQVEVKLKENAYKVYIDELEELEFDSKVFILSNPKISGLHLKTLLSKIKAKEIFIATVKD
CEEEEEECCCCEEEEEHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHCCCEEEEEEECC
GEEYKNLSTMEEILNQMFNSKLDRKSVLISFGGGVISDMGGFAASIYQRGIDFINIPTTL
CHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCEEEHHHHH
LACVDAAVGGKTGVNNNFGKNLIGTFYQPKAVYCESFFLKTLSSRELAAGMAEFIKMAAM
HHHHHHHCCCCCCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
FDYSILDFIEKIDEKSFLNATCENEIFTQIIAKSIELKSRVVEQDEKESRLRMLLNYGHT
HHHHHHHHHHHHCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHH
FAHVIENFTDYKLYLHGEAVAIGMVMANQLALNLGLLDKMQSQRIKDILLKFGLPISYKI
HHHHHCCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
NNVDEFYEAFFMDKKSSNKKINFVLASPLGKGLIKGDISKEDIIATLREFQ
CCHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA