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The map label for this gene is yqcB [C]

Identifier: 57237010

GI number: 57237010

Start: 743706

End: 744458

Strand: Direct

Name: yqcB [C]

Synonym: CJE0808

Alternate gene names: 57237010

Gene position: 743706-744458 (Clockwise)

Preceding gene: 57237009

Following gene: 57237011

Centisome position: 41.83

GC content: 29.75

Gene sequence:

>753_bases
ATGCAAGAAAAAGCTTATAAACTCTTAGCTTTGCAAGAAAAAATTTCAAATCGTGAAGCTAAAGATTTGATTGATAAGGG
TTGTGTTTTTTCACATGGAAAAAAAGTTGTGGTTGCTAGAGCTTTGATGAGCGATAAGGCAAGATTTAATGTGATAAAAG
CTAAAAATCCTCAAATTATTTTTGAAGATGATAAGATTATTGCTATTAATAAACCTTATGCTTATGTGAGTGAAGACTTG
GAGAAAAAATTTAATGCCAAGCTTTTAAATCGTTTAGACAAAGAAACAAGCGGTGTGATTTTGCTTTGTAAAGATGAAGA
TTTTAGAAAGCTTTGTATAGAAGAATTTAAAAAACACAGGGTTTATAAAAGTTATATTGCGGTTTTAGATGGGGTTTTGG
CTGAAGAGGTTGAAGTGAATGAGCCTATTTTTACCATAAAAGCAAAAGGTGGGGCATTAAGTAAAGTTTCAAAAGATGGT
TTAAGTGCCTTAAGTATCATTACTCCTATCATGATGCAGTCAAAAAAAACCTTAGCAAAAATAGTCATTCAAACAGGTAG
AACTCATCAAATCAGAGTGCATGCTAAATTTATAAAACATGGCGTTGTAGGTGATGAAAAATATGCTAAAATTTCAAGCG
ATAGAATGTATTTACATAGTTATGAAATTAAAATTTTTGATTATTATTTTAAGGCTGAGCTAGATAATAGTTTTGCAAAA
GTTGGCTTTGAGATAAAAAATTTAGATTTTTAA

Upstream 100 bases:

>100_bases
AAAGATTTAAATGATAAAATTCATTATTTAAATTTAAAAGCTAAAATTTCCAAAAAAGGAAATTTAGATCTTATCATACA
GACCATACAAAAGGGAATTG

Downstream 100 bases:

>100_bases
AGCCATTTAAGAAAAAATTTTGTATAATGCAAGGTTTAATTTAAAAATTTTATAGAAAGGTGATAAAGTGTTTGAGTTAG
TTAGCGAATCTTTTAAATCA

Product: RNA pseudouridylate synthase

Products: NA

Alternate protein names: RNA pseudouridylate synthase; RNA-uridine isomerase [H]

Number of amino acids: Translated: 250; Mature: 250

Protein sequence:

>250_residues
MQEKAYKLLALQEKISNREAKDLIDKGCVFSHGKKVVVARALMSDKARFNVIKAKNPQIIFEDDKIIAINKPYAYVSEDL
EKKFNAKLLNRLDKETSGVILLCKDEDFRKLCIEEFKKHRVYKSYIAVLDGVLAEEVEVNEPIFTIKAKGGALSKVSKDG
LSALSIITPIMMQSKKTLAKIVIQTGRTHQIRVHAKFIKHGVVGDEKYAKISSDRMYLHSYEIKIFDYYFKAELDNSFAK
VGFEIKNLDF

Sequences:

>Translated_250_residues
MQEKAYKLLALQEKISNREAKDLIDKGCVFSHGKKVVVARALMSDKARFNVIKAKNPQIIFEDDKIIAINKPYAYVSEDL
EKKFNAKLLNRLDKETSGVILLCKDEDFRKLCIEEFKKHRVYKSYIAVLDGVLAEEVEVNEPIFTIKAKGGALSKVSKDG
LSALSIITPIMMQSKKTLAKIVIQTGRTHQIRVHAKFIKHGVVGDEKYAKISSDRMYLHSYEIKIFDYYFKAELDNSFAK
VGFEIKNLDF
>Mature_250_residues
MQEKAYKLLALQEKISNREAKDLIDKGCVFSHGKKVVVARALMSDKARFNVIKAKNPQIIFEDDKIIAINKPYAYVSEDL
EKKFNAKLLNRLDKETSGVILLCKDEDFRKLCIEEFKKHRVYKSYIAVLDGVLAEEVEVNEPIFTIKAKGGALSKVSKDG
LSALSIITPIMMQSKKTLAKIVIQTGRTHQIRVHAKFIKHGVVGDEKYAKISSDRMYLHSYEIKIFDYYFKAELDNSFAK
VGFEIKNLDF

Specific function: Unknown

COG id: COG0564

COG function: function code J; Pseudouridylate synthases, 23S RNA-specific

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S4 RNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI23308689, Length=125, Percent_Identity=29.6, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1789155, Length=189, Percent_Identity=25.3968253968254, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1788946, Length=236, Percent_Identity=26.6949152542373, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787327, Length=195, Percent_Identity=28.7179487179487, Blast_Score=73, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17534965, Length=129, Percent_Identity=34.8837209302326, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6320168, Length=170, Percent_Identity=31.1764705882353, Blast_Score=67, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6324506, Length=176, Percent_Identity=27.2727272727273, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020103
- InterPro:   IPR006224
- InterPro:   IPR006145
- InterPro:   IPR002942 [H]

Pfam domain/function: PF00849 PseudoU_synth_2 [H]

EC number: NA

Molecular weight: Translated: 28560; Mature: 28560

Theoretical pI: Translated: 9.85; Mature: 9.85

Prosite motif: PS01129 PSI_RLU

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQEKAYKLLALQEKISNREAKDLIDKGCVFSHGKKVVVARALMSDKARFNVIKAKNPQII
CCCHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCEEEHHHHHCCCHHEEEEECCCCEEE
FEDDKIIAINKPYAYVSEDLEKKFNAKLLNRLDKETSGVILLCKDEDFRKLCIEEFKKHR
EECCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHH
VYKSYIAVLDGVLAEEVEVNEPIFTIKAKGGALSKVSKDGLSALSIITPIMMQSKKTLAK
HHHHHHHHHHHHHHHHEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVIQTGRTHQIRVHAKFIKHGVVGDEKYAKISSDRMYLHSYEIKIFDYYFKAELDNSFAK
HHHHCCCCEEEEEEEHHHHCCCCCCHHHHEECCCEEEEEEEEEEEEEEEEEEHHCCCHHH
VGFEIKNLDF
HCEEEECCCC
>Mature Secondary Structure
MQEKAYKLLALQEKISNREAKDLIDKGCVFSHGKKVVVARALMSDKARFNVIKAKNPQII
CCCHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCEEEHHHHHCCCHHEEEEECCCCEEE
FEDDKIIAINKPYAYVSEDLEKKFNAKLLNRLDKETSGVILLCKDEDFRKLCIEEFKKHR
EECCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHH
VYKSYIAVLDGVLAEEVEVNEPIFTIKAKGGALSKVSKDGLSALSIITPIMMQSKKTLAK
HHHHHHHHHHHHHHHHEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVIQTGRTHQIRVHAKFIKHGVVGDEKYAKISSDRMYLHSYEIKIFDYYFKAELDNSFAK
HHHHCCCCEEEEEEEHHHHCCCCCCHHHHEECCCEEEEEEEEEEEEEEEEEEHHCCCHHH
VGFEIKNLDF
HCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]