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The map label for this gene is ffh [H]

Identifier: 57237011

GI number: 57237011

Start: 744526

End: 745863

Strand: Direct

Name: ffh [H]

Synonym: CJE0809

Alternate gene names: 57237011

Gene position: 744526-745863 (Clockwise)

Preceding gene: 57237010

Following gene: 57237012

Centisome position: 41.88

GC content: 33.26

Gene sequence:

>1338_bases
GTGTTTGAGTTAGTTAGCGAATCTTTTAAATCAGCGATTAATAAATTACGTTTTGTTGATGATGAAAAAGCACTTAAGAA
CGCTTTAGAAACCTTAAAAAAAGCTCTTTTAAAAGCAGATGTTCACCATAAGGTAACTAAAGAGCTTTTGACTTTGATAG
AAGAAGATGTAAAGCAAAACGGAATAGGTCAAAAACAATTTTTAAATGCCATTAAAGTAAATTTAGAAAATATTTTAAGT
GTCAATGGCAAAAATCAAGGTTTTGTTTTTGCTTCTAAACCCCCAACAGTAGTTCTAATGGCAGGTTTGCAAGGGGGCGG
TAAGACTACAAGCACTATCAAACTCGCAAATTATTTAAAATTACGTAATAAAAAAGTTTTAGTTGCAGCTTGTGATTTGC
AGCGTTTAGCAGCAGTGGAGCAACTAAGACAACTTTGTGAAGCTAATGAAATTGAACTTTTCTTTATAGAAAATGAAAAA
GATCCTATTAGAGTTGCTAAAGAGGCTTTAAAAAAGGCTGAAAGTTCCATGGTGGATGTTTTGCTTGTGGATACTGCTGG
ACGTTTGGCTATAGATGAGGCTTTGATGAATGAATTAAAAGCAGTTAAGGATGTTTTAAATCCTGATGAGATTTTCTATG
TTGCTGATGCAATGAGTGGTCAAGATGGGGTTAAGACTGCGGCTAGTTTTAATGAGGCTTTGAATATCAGCGGGGTAATT
TTATCAAAATTTGATGCAGATACTAAAGGTGGAGTAGCCTTGGGTATAGCAAAACAAATCGGTATTCCTTTAAGATTTAT
TGGTGTGGGTGAAAAAGTAGCAGATTTAGAAGTTTTTATACCAGATCGTATAGTAAGTCGTATTATGGGCGAGGGTGATT
TGGCTACTTTAGCTGAAAAAACTGCTGCAGTGATTGATGAAAAAGAAGCTAAAAAACTCAATCAAAAAATTAAAAAAGGG
GAATTTAATTTTAATGATTTTCTTAACCAAATGGAAAGTATTAAAAAATTAGGAAGTATGAAGTCTTTAATCGGTATGAT
ACCAGGACTTGGTGGAATGGCAAATGCGGTAAAAGATATAGATTTGGATAATTCTAAAGAAATTATACACATTAAAGCAA
TGATTTCTTCAATGACTCCAAAAGAAAGAGAAAATCCTGATTTATTAAATAATGCTAGAAAGCGTCGTATAGCAGAGGGA
GCAGGTCTTTCTCAGGTAGAAGTCAATCGTTTTTTAAAACAATTTAGCAATGCAGCAAAACTTGCAAAAAGATTTTCAGG
TAAAAAAGGAATGGAGAGTTTGACACAAATGATGAGTCAAGCTAGAAGACAATTTTAA

Upstream 100 bases:

>100_bases
GTTGGCTTTGAGATAAAAAATTTAGATTTTTAAAGCCATTTAAGAAAAAATTTTGTATAATGCAAGGTTTAATTTAAAAA
TTTTATAGAAAGGTGATAAA

Downstream 100 bases:

>100_bases
ATTTTATTTATAAATACTTTTTATAGTATCTATAAATAAAATTTTTAATTTTTTAAGGAGTATAAATGACAGTTATTAGA
CTTACAAGAATGGGTAGAAC

Product: signal recognition particle protein

Products: NA

Alternate protein names: Fifty-four homolog [H]

Number of amino acids: Translated: 445; Mature: 445

Protein sequence:

>445_residues
MFELVSESFKSAINKLRFVDDEKALKNALETLKKALLKADVHHKVTKELLTLIEEDVKQNGIGQKQFLNAIKVNLENILS
VNGKNQGFVFASKPPTVVLMAGLQGGGKTTSTIKLANYLKLRNKKVLVAACDLQRLAAVEQLRQLCEANEIELFFIENEK
DPIRVAKEALKKAESSMVDVLLVDTAGRLAIDEALMNELKAVKDVLNPDEIFYVADAMSGQDGVKTAASFNEALNISGVI
LSKFDADTKGGVALGIAKQIGIPLRFIGVGEKVADLEVFIPDRIVSRIMGEGDLATLAEKTAAVIDEKEAKKLNQKIKKG
EFNFNDFLNQMESIKKLGSMKSLIGMIPGLGGMANAVKDIDLDNSKEIIHIKAMISSMTPKERENPDLLNNARKRRIAEG
AGLSQVEVNRFLKQFSNAAKLAKRFSGKKGMESLTQMMSQARRQF

Sequences:

>Translated_445_residues
MFELVSESFKSAINKLRFVDDEKALKNALETLKKALLKADVHHKVTKELLTLIEEDVKQNGIGQKQFLNAIKVNLENILS
VNGKNQGFVFASKPPTVVLMAGLQGGGKTTSTIKLANYLKLRNKKVLVAACDLQRLAAVEQLRQLCEANEIELFFIENEK
DPIRVAKEALKKAESSMVDVLLVDTAGRLAIDEALMNELKAVKDVLNPDEIFYVADAMSGQDGVKTAASFNEALNISGVI
LSKFDADTKGGVALGIAKQIGIPLRFIGVGEKVADLEVFIPDRIVSRIMGEGDLATLAEKTAAVIDEKEAKKLNQKIKKG
EFNFNDFLNQMESIKKLGSMKSLIGMIPGLGGMANAVKDIDLDNSKEIIHIKAMISSMTPKERENPDLLNNARKRRIAEG
AGLSQVEVNRFLKQFSNAAKLAKRFSGKKGMESLTQMMSQARRQF
>Mature_445_residues
MFELVSESFKSAINKLRFVDDEKALKNALETLKKALLKADVHHKVTKELLTLIEEDVKQNGIGQKQFLNAIKVNLENILS
VNGKNQGFVFASKPPTVVLMAGLQGGGKTTSTIKLANYLKLRNKKVLVAACDLQRLAAVEQLRQLCEANEIELFFIENEK
DPIRVAKEALKKAESSMVDVLLVDTAGRLAIDEALMNELKAVKDVLNPDEIFYVADAMSGQDGVKTAASFNEALNISGVI
LSKFDADTKGGVALGIAKQIGIPLRFIGVGEKVADLEVFIPDRIVSRIMGEGDLATLAEKTAAVIDEKEAKKLNQKIKKG
EFNFNDFLNQMESIKKLGSMKSLIGMIPGLGGMANAVKDIDLDNSKEIIHIKAMISSMTPKERENPDLLNNARKRRIAEG
AGLSQVEVNRFLKQFSNAAKLAKRFSGKKGMESLTQMMSQARRQF

Specific function: Necessary for efficient export of extracytoplasmic proteins. Binds to the signal sequence when it emerges from the ribosomes [H]

COG id: COG0541

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=427, Percent_Identity=30.2107728337237, Blast_Score=191, Evalue=1e-48,
Organism=Homo sapiens, GI226371618, Length=343, Percent_Identity=32.0699708454811, Blast_Score=186, Evalue=4e-47,
Organism=Homo sapiens, GI23308697, Length=219, Percent_Identity=32.8767123287671, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI295424842, Length=219, Percent_Identity=32.8767123287671, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI89061728, Length=169, Percent_Identity=33.1360946745562, Blast_Score=99, Evalue=6e-21,
Organism=Escherichia coli, GI1788963, Length=420, Percent_Identity=42.3809523809524, Blast_Score=323, Evalue=1e-89,
Organism=Escherichia coli, GI1789874, Length=267, Percent_Identity=35.9550561797753, Blast_Score=145, Evalue=5e-36,
Organism=Caenorhabditis elegans, GI17539958, Length=437, Percent_Identity=29.0617848970252, Blast_Score=188, Evalue=5e-48,
Organism=Caenorhabditis elegans, GI193206261, Length=200, Percent_Identity=37, Blast_Score=105, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6325345, Length=341, Percent_Identity=33.1378299120235, Blast_Score=193, Evalue=4e-50,
Organism=Saccharomyces cerevisiae, GI6320498, Length=226, Percent_Identity=34.5132743362832, Blast_Score=110, Evalue=6e-25,
Organism=Drosophila melanogaster, GI17647949, Length=422, Percent_Identity=29.6208530805687, Blast_Score=176, Evalue=3e-44,
Organism=Drosophila melanogaster, GI24641198, Length=219, Percent_Identity=34.2465753424658, Blast_Score=120, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822
- InterPro:   IPR004780
- InterPro:   IPR004125 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N; PF02978 SRP_SPB [H]

EC number: NA

Molecular weight: Translated: 48878; Mature: 48878

Theoretical pI: Translated: 9.88; Mature: 9.88

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFELVSESFKSAINKLRFVDDEKALKNALETLKKALLKADVHHKVTKELLTLIEEDVKQN
CHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GIGQKQFLNAIKVNLENILSVNGKNQGFVFASKPPTVVLMAGLQGGGKTTSTIKLANYLK
CCCHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHH
LRNKKVLVAACDLQRLAAVEQLRQLCEANEIELFFIENEKDPIRVAKEALKKAESSMVDV
HCCCEEEEEECCHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHEEE
LLVDTAGRLAIDEALMNELKAVKDVLNPDEIFYVADAMSGQDGVKTAASFNEALNISGVI
EEECCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCEEE
LSKFDADTKGGVALGIAKQIGIPLRFIGVGEKVADLEVFIPDRIVSRIMGEGDLATLAEK
EECCCCCCCCCEEEEHHHHHCCCEEEEECCCCHHHHEEECHHHHHHHHHCCCHHHHHHHH
TAAVIDEKEAKKLNQKIKKGEFNFNDFLNQMESIKKLGSMKSLIGMIPGLGGMANAVKDI
HHHHHCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHC
DLDNSKEIIHIKAMISSMTPKERENPDLLNNARKRRIAEGAGLSQVEVNRFLKQFSNAAK
CCCCCCCEEEHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
LAKRFSGKKGMESLTQMMSQARRQF
HHHHHCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFELVSESFKSAINKLRFVDDEKALKNALETLKKALLKADVHHKVTKELLTLIEEDVKQN
CHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GIGQKQFLNAIKVNLENILSVNGKNQGFVFASKPPTVVLMAGLQGGGKTTSTIKLANYLK
CCCHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHH
LRNKKVLVAACDLQRLAAVEQLRQLCEANEIELFFIENEKDPIRVAKEALKKAESSMVDV
HCCCEEEEEECCHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHEEE
LLVDTAGRLAIDEALMNELKAVKDVLNPDEIFYVADAMSGQDGVKTAASFNEALNISGVI
EEECCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHCCCCEEE
LSKFDADTKGGVALGIAKQIGIPLRFIGVGEKVADLEVFIPDRIVSRIMGEGDLATLAEK
EECCCCCCCCCEEEEHHHHHCCCEEEEECCCCHHHHEEECHHHHHHHHHCCCHHHHHHHH
TAAVIDEKEAKKLNQKIKKGEFNFNDFLNQMESIKKLGSMKSLIGMIPGLGGMANAVKDI
HHHHHCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHC
DLDNSKEIIHIKAMISSMTPKERENPDLLNNARKRRIAEGAGLSQVEVNRFLKQFSNAAK
CCCCCCCEEEHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
LAKRFSGKKGMESLTQMMSQARRQF
HHHHHCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]