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The map label for this gene is ywlC [H]

Identifier: 55980762

GI number: 55980762

Start: 758780

End: 759367

Strand: Reverse

Name: ywlC [H]

Synonym: TTHA0793

Alternate gene names: 55980762

Gene position: 759367-758780 (Counterclockwise)

Preceding gene: 55980764

Following gene: 55980761

Centisome position: 41.05

GC content: 69.22

Gene sequence:

>588_bases
ATGGAAAGAGTATACCAGGAAGCCCTGGCCAAAGCGGCGGAGACCCTCAAGGGAGGGGGTTTGGTGGCCTTCCCCACGGA
CACGGTCTGGGGGGTGCTGGCCCTCATGGAGGACGAGGCCGCCTGCAAGAGGATCTACGAGGTCAAGGGCAGGCCCGAGG
ACAAGCCCCTCCAGGTGCTGGTGGCGGACCTGGAAAGCGCCCTAGAGCTCGTGGACCTCGGCCCTCTGGAAGGAAAGTTC
CTGCGCCTGGCGGAGGCCTTCTGGCCCGGGGGGCTCACCGTGGTGGTCCCCGGGAAGGCCATCCCTCCTTGGATCAGCAA
GGACGGCTCCGTGGGCCTCAGAATGCCGGACCACGCCCTTTTGCGGGAGCTCCTCCGCCGCGTGGGGGGGCACGCCGCCG
CCACGAGCCTCAACAAAAGCGGCGAGCCCCCGGTGCGCACGGAGGCCGAGGCCCGGACCTTCGCCGTGGACTTCGTCTTT
CCGGGGGAGGCGGGAGGACTTGCCTCCAGCGTGGTGGACCTCCGCACCGGGGAGGTCCTGCGGGAAGGGGCGATCCCCAA
GGAGGCCCTTCTCGCCCACCTCCGGTAG

Upstream 100 bases:

>100_bases
GTCGCGGAGGAGCCTCGCGGCGGTGCGGAGGTCCTCGGCCTCAATGGTGGCCTCCACCAGACGGCCCTGGCGGTCCCGGG
CCTTATACTGGTAGACCGGC

Downstream 100 bases:

>100_bases
GCCATGGAGGAAGCCCCGAGCCTCAAAACCCTCCTCCTCGCCGTCCTCTTCGCCGCGGGAAGGCCCGTGGCCCTCAAGGA
GCTTAGGGCCCTGGGCCACC

Product: hypothetical protein

Products: NA

Alternate protein names: t(6)A37 threonylcarbamoyladenosine biosynthesis protein YwlC [H]

Number of amino acids: Translated: 195; Mature: 195

Protein sequence:

>195_residues
MERVYQEALAKAAETLKGGGLVAFPTDTVWGVLALMEDEAACKRIYEVKGRPEDKPLQVLVADLESALELVDLGPLEGKF
LRLAEAFWPGGLTVVVPGKAIPPWISKDGSVGLRMPDHALLRELLRRVGGHAAATSLNKSGEPPVRTEAEARTFAVDFVF
PGEAGGLASSVVDLRTGEVLREGAIPKEALLAHLR

Sequences:

>Translated_195_residues
MERVYQEALAKAAETLKGGGLVAFPTDTVWGVLALMEDEAACKRIYEVKGRPEDKPLQVLVADLESALELVDLGPLEGKF
LRLAEAFWPGGLTVVVPGKAIPPWISKDGSVGLRMPDHALLRELLRRVGGHAAATSLNKSGEPPVRTEAEARTFAVDFVF
PGEAGGLASSVVDLRTGEVLREGAIPKEALLAHLR
>Mature_195_residues
MERVYQEALAKAAETLKGGGLVAFPTDTVWGVLALMEDEAACKRIYEVKGRPEDKPLQVLVADLESALELVDLGPLEGKF
LRLAEAFWPGGLTVVVPGKAIPPWISKDGSVGLRMPDHALLRELLRRVGGHAAATSLNKSGEPPVRTEAEARTFAVDFVF
PGEAGGLASSVVDLRTGEVLREGAIPKEALLAHLR

Specific function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (Probable) [H]

COG id: COG0009

COG function: function code J; Putative translation factor (SUA5)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YrdC-like domain [H]

Homologues:

Organism=Escherichia coli, GI2367210, Length=188, Percent_Identity=35.1063829787234, Blast_Score=92, Evalue=2e-20,
Organism=Escherichia coli, GI87081864, Length=189, Percent_Identity=26.4550264550265, Blast_Score=61, Evalue=5e-11,
Organism=Drosophila melanogaster, GI78707274, Length=201, Percent_Identity=31.3432835820896, Blast_Score=77, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR005145
- InterPro:   IPR004388
- InterPro:   IPR006070
- InterPro:   IPR010923 [H]

Pfam domain/function: PF03481 SUA5; PF01300 Sua5_yciO_yrdC [H]

EC number: NA

Molecular weight: Translated: 20856; Mature: 20856

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: PS51163 YRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERVYQEALAKAAETLKGGGLVAFPTDTVWGVLALMEDEAACKRIYEVKGRPEDKPLQVL
CHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
VADLESALELVDLGPLEGKFLRLAEAFWPGGLTVVVPGKAIPPWISKDGSVGLRMPDHAL
HHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCCCHHH
LRELLRRVGGHAAATSLNKSGEPPVRTEAEARTFAVDFVFPGEAGGLASSVVDLRTGEVL
HHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHH
REGAIPKEALLAHLR
HHCCCCHHHHHHHCC
>Mature Secondary Structure
MERVYQEALAKAAETLKGGGLVAFPTDTVWGVLALMEDEAACKRIYEVKGRPEDKPLQVL
CHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
VADLESALELVDLGPLEGKFLRLAEAFWPGGLTVVVPGKAIPPWISKDGSVGLRMPDHAL
HHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCCCHHH
LRELLRRVGGHAAATSLNKSGEPPVRTEAEARTFAVDFVFPGEAGGLASSVVDLRTGEVL
HHHHHHHHCCCHHHHCCCCCCCCCCCCCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHH
REGAIPKEALLAHLR
HHCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]