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The map label for this gene is aroC [H]

Identifier: 54295142

GI number: 54295142

Start: 2540298

End: 2541356

Strand: Reverse

Name: aroC [H]

Synonym: lpl2222

Alternate gene names: 54295142

Gene position: 2541356-2540298 (Counterclockwise)

Preceding gene: 54295143

Following gene: 54295141

Centisome position: 75.96

GC content: 42.87

Gene sequence:

>1059_bases
ATGTCAGGGAATACCTTTGGAGCGTTATTTACTGTAACAACCTTTGGTGAAAGCCACGGTCCTGCTATCGGATGTGTAGT
TGATGGTTGTCCTCCCGGCATGTCTTTAACTGAAGCAGATATCCAACCTTTTTTAGACAAACGTAAACCAGGTCAATCTA
AATATACTACCCAGAGACGAGAGGAAGATAAGGTACAGATTCTTTCTGGTGTATTTGATGGGAAAACGACAGGAGCTCCC
ATTGCATTGCTGATACAGAATACTGATCAGCGTTCCCGGGATTATGAAGACATTAAAAATTTGTTCCGTCCAGGACATGC
TGATTTTACCTATCATTATAAATATGGGCATAGAGATTATAGAGGGGGAGGCCGTTCTTCCGCTCGTGAGACAGCCGCAC
GAGTCGCTGCCGGTGCCATTGCCAGATTGTATTTAAAGCGTTATTTAAACCTGGATATTATTGGTTATTTACAACAAATG
GGCGATTTGAAGTTACAGTTTGAAAATGAAAATGAAATCGATAAAAATCCCTTTTTTTGTCCTAATAATAAGCAAATTCA
AGAGCTGGCTGATTATGTAGATCGCTTGAGACGCCAGGGTGATTCCGTTGGGGCTCGAGTGAAGATACTGGCACGGGGAG
TGCCAACAGGGTTGGGAGATCCGGTATTTGATAAACTGGACGCTACTCTTGCTTATGCAATGATGTCAATTAATGCTGTT
AAAGGTGTTGAAATTGGAGCTGGTTTTAATGCAGTAGAGCAGTTAGGAAGTCATCATAGAGATCAGATGACTGCCAAGGG
ATTCTTGAGTAATCATGCTGGTGGTATTTTAGGAGGCATAGCAACAGGACAACCCATCGAAGTGAGCATCGCTTTAAAGC
CAACTTCAAGCATCACAACTCCAGGTCAGACCATTAATACTGAAGGTGAAGAGGTTACTGTAGTAACCAAAGGGCGTCAT
GATCCCTGCGTGGGGATAAGGGCTGTGCCAATTGCAGAGGCAATGATGGCTTTGGTGTTAATGGATCATTATTTACGGCA
TAAAGCGCAGTGTAAATAA

Upstream 100 bases:

>100_bases
TGGTTCCTTTTACCTGGCTTGAAATGAGCAACGGCGGGCAAGGGGTGTTTTTATTAACAAAACAGCAATTAGAAGACTAT
TTTAAATAAGCGAGTAAGGC

Downstream 100 bases:

>100_bases
TAAATTATAACGTTTCAAAATATAGCCATATCGTAGTTCGTTTTCTGCTTCGCAAGCAGGAATTGAACTTGACTAGCACA
TTGTTAATTGATGGTAAGAT

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase [H]

Number of amino acids: Translated: 352; Mature: 351

Protein sequence:

>352_residues
MSGNTFGALFTVTTFGESHGPAIGCVVDGCPPGMSLTEADIQPFLDKRKPGQSKYTTQRREEDKVQILSGVFDGKTTGAP
IALLIQNTDQRSRDYEDIKNLFRPGHADFTYHYKYGHRDYRGGGRSSARETAARVAAGAIARLYLKRYLNLDIIGYLQQM
GDLKLQFENENEIDKNPFFCPNNKQIQELADYVDRLRRQGDSVGARVKILARGVPTGLGDPVFDKLDATLAYAMMSINAV
KGVEIGAGFNAVEQLGSHHRDQMTAKGFLSNHAGGILGGIATGQPIEVSIALKPTSSITTPGQTINTEGEEVTVVTKGRH
DPCVGIRAVPIAEAMMALVLMDHYLRHKAQCK

Sequences:

>Translated_352_residues
MSGNTFGALFTVTTFGESHGPAIGCVVDGCPPGMSLTEADIQPFLDKRKPGQSKYTTQRREEDKVQILSGVFDGKTTGAP
IALLIQNTDQRSRDYEDIKNLFRPGHADFTYHYKYGHRDYRGGGRSSARETAARVAAGAIARLYLKRYLNLDIIGYLQQM
GDLKLQFENENEIDKNPFFCPNNKQIQELADYVDRLRRQGDSVGARVKILARGVPTGLGDPVFDKLDATLAYAMMSINAV
KGVEIGAGFNAVEQLGSHHRDQMTAKGFLSNHAGGILGGIATGQPIEVSIALKPTSSITTPGQTINTEGEEVTVVTKGRH
DPCVGIRAVPIAEAMMALVLMDHYLRHKAQCK
>Mature_351_residues
SGNTFGALFTVTTFGESHGPAIGCVVDGCPPGMSLTEADIQPFLDKRKPGQSKYTTQRREEDKVQILSGVFDGKTTGAPI
ALLIQNTDQRSRDYEDIKNLFRPGHADFTYHYKYGHRDYRGGGRSSARETAARVAAGAIARLYLKRYLNLDIIGYLQQMG
DLKLQFENENEIDKNPFFCPNNKQIQELADYVDRLRRQGDSVGARVKILARGVPTGLGDPVFDKLDATLAYAMMSINAVK
GVEIGAGFNAVEQLGSHHRDQMTAKGFLSNHAGGILGGIATGQPIEVSIALKPTSSITTPGQTINTEGEEVTVVTKGRHD
PCVGIRAVPIAEAMMALVLMDHYLRHKAQCK

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788669, Length=350, Percent_Identity=65.7142857142857, Blast_Score=463, Evalue=1e-132,
Organism=Saccharomyces cerevisiae, GI6321290, Length=367, Percent_Identity=47.1389645776567, Blast_Score=327, Evalue=2e-90,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000453
- InterPro:   IPR020541 [H]

Pfam domain/function: PF01264 Chorismate_synt [H]

EC number: =4.2.3.5 [H]

Molecular weight: Translated: 38401; Mature: 38270

Theoretical pI: Translated: 8.21; Mature: 8.21

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1 ; PS00788 CHORISMATE_SYNTHASE_2 ; PS00789 CHORISMATE_SYNTHASE_3 ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGNTFGALFTVTTFGESHGPAIGCVVDGCPPGMSLTEADIQPFLDKRKPGQSKYTTQRR
CCCCCEEEEEEEEECCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHH
EEDKVQILSGVFDGKTTGAPIALLIQNTDQRSRDYEDIKNLFRPGHADFTYHYKYGHRDY
HHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHCCCCCCEEEEEECCCCCC
RGGGRSSARETAARVAAGAIARLYLKRYLNLDIIGYLQQMGDLKLQFENENEIDKNPFFC
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCEEEEECCCCCCCCCCCCC
PNNKQIQELADYVDRLRRQGDSVGARVKILARGVPTGLGDPVFDKLDATLAYAMMSINAV
CCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHH
KGVEIGAGFNAVEQLGSHHRDQMTAKGFLSNHAGGILGGIATGQPIEVSIALKPTSSITT
CCEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCEEEEEEECCCCCCCC
PGQTINTEGEEVTVVTKGRHDPCVGIRAVPIAEAMMALVLMDHYLRHKAQCK
CCCEECCCCCEEEEEECCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SGNTFGALFTVTTFGESHGPAIGCVVDGCPPGMSLTEADIQPFLDKRKPGQSKYTTQRR
CCCCEEEEEEEEECCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHH
EEDKVQILSGVFDGKTTGAPIALLIQNTDQRSRDYEDIKNLFRPGHADFTYHYKYGHRDY
HHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHCCCCCCEEEEEECCCCCC
RGGGRSSARETAARVAAGAIARLYLKRYLNLDIIGYLQQMGDLKLQFENENEIDKNPFFC
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCEEEEECCCCCCCCCCCCC
PNNKQIQELADYVDRLRRQGDSVGARVKILARGVPTGLGDPVFDKLDATLAYAMMSINAV
CCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHH
KGVEIGAGFNAVEQLGSHHRDQMTAKGFLSNHAGGILGGIATGQPIEVSIALKPTSSITT
CCEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCEEEEEEECCCCCCCC
PGQTINTEGEEVTVVTKGRHDPCVGIRAVPIAEAMMALVLMDHYLRHKAQCK
CCCEECCCCCEEEEEECCCCCCCCCEEECHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA