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The map label for this gene is asd [H]

Identifier: 54295141

GI number: 54295141

Start: 2539166

End: 2540188

Strand: Reverse

Name: asd [H]

Synonym: lpl2221

Alternate gene names: 54295141

Gene position: 2540188-2539166 (Counterclockwise)

Preceding gene: 54295142

Following gene: 54295140

Centisome position: 75.92

GC content: 43.7

Gene sequence:

>1023_bases
ATGAGCAGACATTTGAATGTAGCTATCGTAGGTGCCACCGGCGCTGTTGGAGAAACCTTTTTAACCGTTTTGGAAGAAAG
AAATTTTCCAATTAAGTCCCTTTACCCATTAGCGAGTTCTCGCTCAGTAGGTAAGACAGTGACTTTTAGAGATCAGGAAT
TGGATGTTTTGGATTTAGCAGAATTTGATTTTAGCAAAGTCGATCTTGCTTTATTCTCTGCAGGCGGCGCTGTTTCAAAA
GAGTATGCACCAAAAGCTGTGGCTGCTGGGTGCGTGGTGGTTGATAATACCTCCTGTTTTCGTTATGAGGATGATATTCC
TCTTGTTGTCCCTGAAGTGAATCCTCATCGAATCGCTGATTATACTAAAAGAGGCATTATTGCTAACCCTAATTGCTCTA
CCATTCAGATGGTCGTTGCTCTAAAGCCAATCTATGACGCTGTTGGTATTAGTCGTATTAATGTGGCGACTTACCAGTCT
GTTTCCGGGACTGGCAAAAAAGCCATCAGCGAGCTGGTTGCTCAGGTAGGCGATCTTTTAAATGGGAGGCCAGCTAATGT
TCAAGTTTATCCTCAGCAAATTGCTTTTAATGCGCTTCCTCATATTGATCAGTTCGAAGACAATGGTTATACCCGAGAAG
AGATGAAGATGGTCTGGGAAACCCGCAAGATTATGGAAGATGACAGCATTATGGTTAACCCTACAGCCGTCAGAGTTCCT
GTTATTTATGGGCATTCTGAAGCGGTTCATCTTGAGTTAAAAAAGCCTTTGACGGCTGACGATGCTCGCGCGCTTTTGGC
AAAGGCACCCGGCGTTACTGTAGTGGATAATCTTTCTAAAGCACGTTATCCCACAGCAATTAAGAATGCAGTCGGGCATG
ATGATGTTTTTGTAGGGCGCATAAGACAGGATATTTCTCATCCTTGTGGACTAAATTTGTGGATAGTCGCAGATAACATT
CGCAAAGGTGCGGCAACTAACGCGGTACAGATCGCTGAAATACTGCAAAGAGAGTTTCTGTGA

Upstream 100 bases:

>100_bases
ACGTTTCAAAATATAGCCATATCGTAGTTCGTTTTCTGCTTCGCAAGCAGGAATTGAACTTGACTAGCACATTGTTAATT
GATGGTAAGATGAGGTCATA

Downstream 100 bases:

>100_bases
AGCTCTCTTTGCCGCAATAACAGAGATTCAGTATCTTGATAGCAAACTTGTATGTCCTCTATCGGCCATGCAGGTTATGT
TAGAAAAAATGCCATACTTT

Product: aspartate-semialdehyde dehydrogenase

Products: NA

Alternate protein names: ASA dehydrogenase; ASADH [H]

Number of amino acids: Translated: 340; Mature: 339

Protein sequence:

>340_residues
MSRHLNVAIVGATGAVGETFLTVLEERNFPIKSLYPLASSRSVGKTVTFRDQELDVLDLAEFDFSKVDLALFSAGGAVSK
EYAPKAVAAGCVVVDNTSCFRYEDDIPLVVPEVNPHRIADYTKRGIIANPNCSTIQMVVALKPIYDAVGISRINVATYQS
VSGTGKKAISELVAQVGDLLNGRPANVQVYPQQIAFNALPHIDQFEDNGYTREEMKMVWETRKIMEDDSIMVNPTAVRVP
VIYGHSEAVHLELKKPLTADDARALLAKAPGVTVVDNLSKARYPTAIKNAVGHDDVFVGRIRQDISHPCGLNLWIVADNI
RKGAATNAVQIAEILQREFL

Sequences:

>Translated_340_residues
MSRHLNVAIVGATGAVGETFLTVLEERNFPIKSLYPLASSRSVGKTVTFRDQELDVLDLAEFDFSKVDLALFSAGGAVSK
EYAPKAVAAGCVVVDNTSCFRYEDDIPLVVPEVNPHRIADYTKRGIIANPNCSTIQMVVALKPIYDAVGISRINVATYQS
VSGTGKKAISELVAQVGDLLNGRPANVQVYPQQIAFNALPHIDQFEDNGYTREEMKMVWETRKIMEDDSIMVNPTAVRVP
VIYGHSEAVHLELKKPLTADDARALLAKAPGVTVVDNLSKARYPTAIKNAVGHDDVFVGRIRQDISHPCGLNLWIVADNI
RKGAATNAVQIAEILQREFL
>Mature_339_residues
SRHLNVAIVGATGAVGETFLTVLEERNFPIKSLYPLASSRSVGKTVTFRDQELDVLDLAEFDFSKVDLALFSAGGAVSKE
YAPKAVAAGCVVVDNTSCFRYEDDIPLVVPEVNPHRIADYTKRGIIANPNCSTIQMVVALKPIYDAVGISRINVATYQSV
SGTGKKAISELVAQVGDLLNGRPANVQVYPQQIAFNALPHIDQFEDNGYTREEMKMVWETRKIMEDDSIMVNPTAVRVPV
IYGHSEAVHLELKKPLTADDARALLAKAPGVTVVDNLSKARYPTAIKNAVGHDDVFVGRIRQDISHPCGLNLWIVADNIR
KGAATNAVQIAEILQREFL

Specific function: Unknown

COG id: COG0136

COG function: function code E; Aspartate-semialdehyde dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aspartate-semialdehyde dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788658, Length=341, Percent_Identity=40.7624633431085, Blast_Score=270, Evalue=1e-73,
Organism=Escherichia coli, GI1789841, Length=366, Percent_Identity=28.4153005464481, Blast_Score=99, Evalue=5e-22,
Organism=Saccharomyces cerevisiae, GI6320362, Length=389, Percent_Identity=29.5629820051414, Blast_Score=93, Evalue=6e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012080
- InterPro:   IPR005986
- InterPro:   IPR016040
- InterPro:   IPR000534
- InterPro:   IPR012280 [H]

Pfam domain/function: PF01118 Semialdhyde_dh; PF02774 Semialdhyde_dhC [H]

EC number: =1.2.1.11 [H]

Molecular weight: Translated: 37116; Mature: 36985

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRHLNVAIVGATGAVGETFLTVLEERNFPIKSLYPLASSRSVGKTVTFRDQELDVLDLA
CCCCEEEEEEECCCCHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCEEEEECCCCCEEEHH
EFDFSKVDLALFSAGGAVSKEYAPKAVAAGCVVVDNTSCFRYEDDIPLVVPEVNPHRIAD
HCCCCCEEEEEEECCCCCCHHCCCHHHHCCEEEEECCCEEEECCCCCEEECCCCCHHHHH
YTKRGIIANPNCSTIQMVVALKPIYDAVGISRINVATYQSVSGTGKKAISELVAQVGDLL
HHHCCEEECCCCCCEEEEEEHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHH
NGRPANVQVYPQQIAFNALPHIDQFEDNGYTREEMKMVWETRKIMEDDSIMVNPTAVRVP
CCCCCCEEECHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEECCCEEEEE
VIYGHSEAVHLELKKPLTADDARALLAKAPGVTVVDNLSKARYPTAIKNAVGHDDVFVGR
EEECCCCEEEEEECCCCCCCHHHHHHHCCCCCEEECCCHHHCCCHHHHHCCCCCCHHHHH
IRQDISHPCGLNLWIVADNIRKGAATNAVQIAEILQREFL
HHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
SRHLNVAIVGATGAVGETFLTVLEERNFPIKSLYPLASSRSVGKTVTFRDQELDVLDLA
CCCEEEEEEECCCCHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCEEEEECCCCCEEEHH
EFDFSKVDLALFSAGGAVSKEYAPKAVAAGCVVVDNTSCFRYEDDIPLVVPEVNPHRIAD
HCCCCCEEEEEEECCCCCCHHCCCHHHHCCEEEEECCCEEEECCCCCEEECCCCCHHHHH
YTKRGIIANPNCSTIQMVVALKPIYDAVGISRINVATYQSVSGTGKKAISELVAQVGDLL
HHHCCEEECCCCCCEEEEEEHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHH
NGRPANVQVYPQQIAFNALPHIDQFEDNGYTREEMKMVWETRKIMEDDSIMVNPTAVRVP
CCCCCCEEECHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEECCCEEEEE
VIYGHSEAVHLELKKPLTADDARALLAKAPGVTVVDNLSKARYPTAIKNAVGHDDVFVGR
EEECCCCEEEEEECCCCCCCHHHHHHHCCCCCEEECCCHHHCCCHHHHHCCCCCCHHHHH
IRQDISHPCGLNLWIVADNIRKGAATNAVQIAEILQREFL
HHHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9573067 [H]