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The map label for this gene is yfcB [C]

Identifier: 54295143

GI number: 54295143

Start: 2541368

End: 2542300

Strand: Reverse

Name: yfcB [C]

Synonym: lpl2223

Alternate gene names: 54295143

Gene position: 2542300-2541368 (Counterclockwise)

Preceding gene: 54295149

Following gene: 54295142

Centisome position: 75.99

GC content: 39.12

Gene sequence:

>933_bases
ATGGTTATGGTTGATACGCTTGTGAGTAGTTATTTTAGCAAGGAAACAGAAGAACTGGTTACTATTCTGGATTTTTTACG
GTTTAGTTTGTCTTGTGCAGAAAACGCGCAATTATTTTATGGCCACGGAACTGACAACGCTTGGGATGACATGAGATCCC
TGATATTGAGAAGCTTGTCTTTACCATACGATGTCGACCCTTTTTTGTTGAATGCACGTTTAACAACCAGTGAACGCAAA
CATCTTTGTAATCAATTGGATAAACGAATTAATCAAAGAGTACCCGTACCTTATTTAATTAAGGAAGCCTATTTTTGCGA
TTTGCCTTTCTATGTTGACGAACGAGTGCTTATACCCAGATCACCAATAGGAGAGTTAATCAATAATCAATTTTCCCCTT
GGATAGAAGCAGAACAAGTGCATCATGTTTTGGATTTATGTACCGGGAGTGGTTGTATAGCGATTGCCTGTTGTTATGCA
TTCCCTGAGGCTCAGGTGGATGCTGTGGATATTTCAAATCAAGCATTGGCTGTCGCTACTATTAATTGTGAACGTCATGA
TGTAGGCGATCAATTGGCACTGATTGAATCGGATTGTTTTACGGCACTGTCAGGTAAACAATATGATTTGATTGTGAGCA
ATCCTCCTTATGTGGGGAAGGAAGAGATGCAGACCCTGCCAGATGAATACCGCCATGAACCGGTTTTGGCATTGGAAACA
GGAAATAATGGCTTGGCTATTATTGAAAAAATTTTAAAGAATGCTCATGCTTATTTAAGTGAACATGGTATTTTGGTAGT
GGAAGTAGGTAATAGTGAAGAGGCTTTATGCGAGACTTATCCTATGGTTCCTTTTACCTGGCTTGAAATGAGCAACGGCG
GGCAAGGGGTGTTTTTATTAACAAAACAGCAATTAGAAGACTATTTTAAATAA

Upstream 100 bases:

>100_bases
GGTGAAAATCAAGCCATGCGAAGGGGCGTCTTAAATCGCACCCCTTAACAAAGAATACAGGACATAGATTTTAATTTAGT
GTACAATTTGTACTTTTTCT

Downstream 100 bases:

>100_bases
GCGAGTAAGGCATGTCAGGGAATACCTTTGGAGCGTTATTTACTGTAACAACCTTTGGTGAAAGCCACGGTCCTGCTATC
GGATGTGTAGTTGATGGTTG

Product: N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MVMVDTLVSSYFSKETEELVTILDFLRFSLSCAENAQLFYGHGTDNAWDDMRSLILRSLSLPYDVDPFLLNARLTTSERK
HLCNQLDKRINQRVPVPYLIKEAYFCDLPFYVDERVLIPRSPIGELINNQFSPWIEAEQVHHVLDLCTGSGCIAIACCYA
FPEAQVDAVDISNQALAVATINCERHDVGDQLALIESDCFTALSGKQYDLIVSNPPYVGKEEMQTLPDEYRHEPVLALET
GNNGLAIIEKILKNAHAYLSEHGILVVEVGNSEEALCETYPMVPFTWLEMSNGGQGVFLLTKQQLEDYFK

Sequences:

>Translated_310_residues
MVMVDTLVSSYFSKETEELVTILDFLRFSLSCAENAQLFYGHGTDNAWDDMRSLILRSLSLPYDVDPFLLNARLTTSERK
HLCNQLDKRINQRVPVPYLIKEAYFCDLPFYVDERVLIPRSPIGELINNQFSPWIEAEQVHHVLDLCTGSGCIAIACCYA
FPEAQVDAVDISNQALAVATINCERHDVGDQLALIESDCFTALSGKQYDLIVSNPPYVGKEEMQTLPDEYRHEPVLALET
GNNGLAIIEKILKNAHAYLSEHGILVVEVGNSEEALCETYPMVPFTWLEMSNGGQGVFLLTKQQLEDYFK
>Mature_310_residues
MVMVDTLVSSYFSKETEELVTILDFLRFSLSCAENAQLFYGHGTDNAWDDMRSLILRSLSLPYDVDPFLLNARLTTSERK
HLCNQLDKRINQRVPVPYLIKEAYFCDLPFYVDERVLIPRSPIGELINNQFSPWIEAEQVHHVLDLCTGSGCIAIACCYA
FPEAQVDAVDISNQALAVATINCERHDVGDQLALIESDCFTALSGKQYDLIVSNPPYVGKEEMQTLPDEYRHEPVLALET
GNNGLAIIEKILKNAHAYLSEHGILVVEVGNSEEALCETYPMVPFTWLEMSNGGQGVFLLTKQQLEDYFK

Specific function: Unknown

COG id: COG2890

COG function: function code J; Methylase of polypeptide chain release factors

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI7705409, Length=219, Percent_Identity=31.0502283105023, Blast_Score=86, Evalue=3e-17,
Organism=Escherichia coli, GI87082085, Length=295, Percent_Identity=55.5932203389831, Blast_Score=335, Evalue=3e-93,
Organism=Escherichia coli, GI1787463, Length=191, Percent_Identity=32.9842931937173, Blast_Score=102, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24582226, Length=194, Percent_Identity=29.3814432989691, Blast_Score=82, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002052
- InterPro:   IPR004556
- InterPro:   IPR017127
- InterPro:   IPR007848 [H]

Pfam domain/function: PF05175 MTS [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 34940; Mature: 34940

Theoretical pI: Translated: 4.28; Mature: 4.28

Prosite motif: PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVMVDTLVSSYFSKETEELVTILDFLRFSLSCAENAQLFYGHGTDNAWDDMRSLILRSLS
CEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHCC
LPYDVDPFLLNARLTTSERKHLCNQLDKRINQRVPVPYLIKEAYFCDLPFYVDERVLIPR
CCCCCCCEEEEEEECCHHHHHHHHHHHHHHHCCCCCCHHHHHHEEECCCCEECCEEECCC
SPIGELINNQFSPWIEAEQVHHVLDLCTGSGCIAIACCYAFPEAQVDAVDISNQALAVAT
CHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCHHHHHEEHHCCCCCEEEEECCCCEEEEEE
INCERHDVGDQLALIESDCFTALSGKQYDLIVSNPPYVGKEEMQTLPDEYRHEPVLALET
EECCCCCCCCCEEEEHHHHHHHCCCCEEEEEECCCCCCCHHHHHHCCHHHCCCCEEEEEE
GNNGLAIIEKILKNAHAYLSEHGILVVEVGNSEEALCETYPMVPFTWLEMSNGGQGVFLL
CCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHCCCCCEEEEEECCCCCEEEEE
TKQQLEDYFK
EHHHHHHHCC
>Mature Secondary Structure
MVMVDTLVSSYFSKETEELVTILDFLRFSLSCAENAQLFYGHGTDNAWDDMRSLILRSLS
CEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHCC
LPYDVDPFLLNARLTTSERKHLCNQLDKRINQRVPVPYLIKEAYFCDLPFYVDERVLIPR
CCCCCCCEEEEEEECCHHHHHHHHHHHHHHHCCCCCCHHHHHHEEECCCCEECCEEECCC
SPIGELINNQFSPWIEAEQVHHVLDLCTGSGCIAIACCYAFPEAQVDAVDISNQALAVAT
CHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCHHHHHEEHHCCCCCEEEEECCCCEEEEEE
INCERHDVGDQLALIESDCFTALSGKQYDLIVSNPPYVGKEEMQTLPDEYRHEPVLALET
EECCCCCCCCCEEEEHHHHHHHCCCCEEEEEECCCCCCCHHHHHHCCHHHCCCCEEEEEE
GNNGLAIIEKILKNAHAYLSEHGILVVEVGNSEEALCETYPMVPFTWLEMSNGGQGVFLL
CCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHCCCCCEEEEEECCCCCEEEEE
TKQQLEDYFK
EHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]