Click here to switch to the map view.

The map label for this gene is csd [H]

Identifier: 54293587

GI number: 54293587

Start: 690531

End: 691775

Strand: Direct

Name: csd [H]

Synonym: lpl0639

Alternate gene names: 54293587

Gene position: 690531-691775 (Clockwise)

Preceding gene: 54293586

Following gene: 54293588

Centisome position: 20.64

GC content: 40.08

Gene sequence:

>1245_bases
ATGAGTACTAATCCTTCATTAATGACATCCTTTGATGTCAACAAAATCAGGAAAGATTTCCCTGTATTGCATCAGAAAAT
CAATGAGTATGATTTGGTGTATTTTGATAATGCGGCTACTACTCAAAAACCCAAGGCTGTGATTGATGCTATTGCTCAAT
TTTATGAAAGGGATAATTCCAACGTACATCGTGGAGTTCATGCCTTGAGTGTCAGGGCTACGGAAATGTATGAGGCAGCA
AGAGCTAAAGTAAAACGATTTATTAATGCCAGATCACCGAGAGAATGTATTTTTGTGCGCGGTACGACAGAAGCCATTAA
CTTAGTAGCCCAGAGTCTCGTAGCCCCTCGCATATTACCTGATGAAGAAATTTTGATAACCCATATGGAACATCATTCCA
ATATAGTTCCTTGGCAAATGGTCTGTAAGAAAATGGGTTGCAAGCTGCAAGTTGCCCCTATTTCTTTAAATGGCGAGGTA
ATACTTGAAGAGTTTGAAAGAAAGTTAAATGAAAACACTAAAATGGTTGCGATTAATTACGCCTCCAATTCTTTAGGAAC
TATTAATCCTGTTAAAACAATGATTAAGATGGCACATGAAGTAGGGGCTAAAGTGTTACTGGATGGGGCACAGGCAACGG
CTCACCTGATTGTGGACGTTCAAGATCTGGATTGCGATTTCTATGCTTTTTCCGGACATAAAATGTATGGTCCCACTGGA
ATAGGTGTTTTATGGGGAAAAGAAGAATTATTAAATAGCATGACTCCTTATCAGGGCGGGGGTGAAATGATCAACTCCGT
GAGTTTTGAGGCAACAGAATATGCGGCTATCCCCCATAAATTTGAAGCAGGCACCCCGAATATTGCAGGGGCTATTGGTC
TGGCTGCTGCAATTGATTATATTTGGTCATTGGATTTGGATGCGATAGCTGAATACGAAACACAATTGTTAAACTATGCT
ACCAAGGCTATTGAAGCAGTAAAAGGGTACAATATTATTGGAACGGCTGCCAACAAAGTACCCATTATCTCTTTTGTCCA
CGGAAAAATTCATGCCCATGACATTGGAACTATTCTGGATAGTGAAGGTATAGCGATACGCAGCGGACATCACTGCACTA
TGCCTTTGATGGATTTCTACGATGTCGCTGCGACCTCTCGTATTTCCATGTCCTTTTATAATACGTTTAAAGAAATTGAT
TATTGTATGGAAGCCTTACAACGAGTTAAAGAGGTATTCGCATGA

Upstream 100 bases:

>100_bases
TTGATCCAGGCATTTGCCAATGATAATTTGCGCCTTATTCCAAATCGTGATTTGGCTGATTGGATGGGTAATTTATTAAC
TCAACAGTTGGGGTACGCAA

Downstream 100 bases:

>100_bases
GTATGGAGTTGCGGGAACTTTACCAGGAAATCATTATCGATCACAATCGTAATCCTCGTAACCACCATGCGATGGAGGAT
GCGACTACCGAGGCGAAAGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 414; Mature: 413

Protein sequence:

>414_residues
MSTNPSLMTSFDVNKIRKDFPVLHQKINEYDLVYFDNAATTQKPKAVIDAIAQFYERDNSNVHRGVHALSVRATEMYEAA
RAKVKRFINARSPRECIFVRGTTEAINLVAQSLVAPRILPDEEILITHMEHHSNIVPWQMVCKKMGCKLQVAPISLNGEV
ILEEFERKLNENTKMVAINYASNSLGTINPVKTMIKMAHEVGAKVLLDGAQATAHLIVDVQDLDCDFYAFSGHKMYGPTG
IGVLWGKEELLNSMTPYQGGGEMINSVSFEATEYAAIPHKFEAGTPNIAGAIGLAAAIDYIWSLDLDAIAEYETQLLNYA
TKAIEAVKGYNIIGTAANKVPIISFVHGKIHAHDIGTILDSEGIAIRSGHHCTMPLMDFYDVAATSRISMSFYNTFKEID
YCMEALQRVKEVFA

Sequences:

>Translated_414_residues
MSTNPSLMTSFDVNKIRKDFPVLHQKINEYDLVYFDNAATTQKPKAVIDAIAQFYERDNSNVHRGVHALSVRATEMYEAA
RAKVKRFINARSPRECIFVRGTTEAINLVAQSLVAPRILPDEEILITHMEHHSNIVPWQMVCKKMGCKLQVAPISLNGEV
ILEEFERKLNENTKMVAINYASNSLGTINPVKTMIKMAHEVGAKVLLDGAQATAHLIVDVQDLDCDFYAFSGHKMYGPTG
IGVLWGKEELLNSMTPYQGGGEMINSVSFEATEYAAIPHKFEAGTPNIAGAIGLAAAIDYIWSLDLDAIAEYETQLLNYA
TKAIEAVKGYNIIGTAANKVPIISFVHGKIHAHDIGTILDSEGIAIRSGHHCTMPLMDFYDVAATSRISMSFYNTFKEID
YCMEALQRVKEVFA
>Mature_413_residues
STNPSLMTSFDVNKIRKDFPVLHQKINEYDLVYFDNAATTQKPKAVIDAIAQFYERDNSNVHRGVHALSVRATEMYEAAR
AKVKRFINARSPRECIFVRGTTEAINLVAQSLVAPRILPDEEILITHMEHHSNIVPWQMVCKKMGCKLQVAPISLNGEVI
LEEFERKLNENTKMVAINYASNSLGTINPVKTMIKMAHEVGAKVLLDGAQATAHLIVDVQDLDCDFYAFSGHKMYGPTGI
GVLWGKEELLNSMTPYQGGGEMINSVSFEATEYAAIPHKFEAGTPNIAGAIGLAAAIDYIWSLDLDAIAEYETQLLNYAT
KAIEAVKGYNIIGTAANKVPIISFVHGKIHAHDIGTILDSEGIAIRSGHHCTMPLMDFYDVAATSRISMSFYNTFKEIDY
CMEALQRVKEVFA

Specific function: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine [H]

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=399, Percent_Identity=23.5588972431078, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI156713448, Length=426, Percent_Identity=24.4131455399061, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1787970, Length=405, Percent_Identity=50.8641975308642, Blast_Score=434, Evalue=1e-123,
Organism=Escherichia coli, GI1789175, Length=406, Percent_Identity=39.1625615763547, Blast_Score=314, Evalue=8e-87,
Organism=Escherichia coli, GI48994898, Length=398, Percent_Identity=23.6180904522613, Blast_Score=96, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI25143064, Length=213, Percent_Identity=29.5774647887324, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI193211090, Length=341, Percent_Identity=26.099706744868, Blast_Score=87, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6319831, Length=399, Percent_Identity=24.5614035087719, Blast_Score=105, Evalue=1e-23,
Organism=Drosophila melanogaster, GI20129463, Length=398, Percent_Identity=24.3718592964824, Blast_Score=111, Evalue=1e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR010970
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 45913; Mature: 45782

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTNPSLMTSFDVNKIRKDFPVLHQKINEYDLVYFDNAATTQKPKAVIDAIAQFYERDNS
CCCCCCEEEECCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCC
NVHRGVHALSVRATEMYEAARAKVKRFINARSPRECIFVRGTTEAINLVAQSLVAPRILP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHCCCCCC
DEEILITHMEHHSNIVPWQMVCKKMGCKLQVAPISLNGEVILEEFERKLNENTKMVAINY
CCCEEEEEEHHCCCCCCHHHHHHHHCCEEEEEEEECCCHHHHHHHHHHHCCCCEEEEEEE
ASNSLGTINPVKTMIKMAHEVGAKVLLDGAQATAHLIVDVQDLDCDFYAFSGHKMYGPTG
CCCCCCCCHHHHHHHHHHHHCCCEEEECCCCCEEEEEEEEEECCCCEEEECCCEEECCCC
IGVLWGKEELLNSMTPYQGGGEMINSVSFEATEYAAIPHKFEAGTPNIAGAIGLAAAIDY
CEEEECHHHHHHCCCCCCCCHHHHHCCCCCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHH
IWSLDLDAIAEYETQLLNYATKAIEAVKGYNIIGTAANKVPIISFVHGKIHAHDIGTILD
HHHCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEEEEECCEEEEEHHHHHCC
SEGIAIRSGHHCTMPLMDFYDVAATSRISMSFYNTFKEIDYCMEALQRVKEVFA
CCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
STNPSLMTSFDVNKIRKDFPVLHQKINEYDLVYFDNAATTQKPKAVIDAIAQFYERDNS
CCCCCEEEECCHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCC
NVHRGVHALSVRATEMYEAARAKVKRFINARSPRECIFVRGTTEAINLVAQSLVAPRILP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCHHHHHHHHHHHHCCCCCC
DEEILITHMEHHSNIVPWQMVCKKMGCKLQVAPISLNGEVILEEFERKLNENTKMVAINY
CCCEEEEEEHHCCCCCCHHHHHHHHCCEEEEEEEECCCHHHHHHHHHHHCCCCEEEEEEE
ASNSLGTINPVKTMIKMAHEVGAKVLLDGAQATAHLIVDVQDLDCDFYAFSGHKMYGPTG
CCCCCCCCHHHHHHHHHHHHCCCEEEECCCCCEEEEEEEEEECCCCEEEECCCEEECCCC
IGVLWGKEELLNSMTPYQGGGEMINSVSFEATEYAAIPHKFEAGTPNIAGAIGLAAAIDY
CEEEECHHHHHHCCCCCCCCHHHHHCCCCCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHH
IWSLDLDAIAEYETQLLNYATKAIEAVKGYNIIGTAANKVPIISFVHGKIHAHDIGTILD
HHHCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCEEEEEECCEEEEEHHHHHCC
SEGIAIRSGHHCTMPLMDFYDVAATSRISMSFYNTFKEIDYCMEALQRVKEVFA
CCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]