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The map label for this gene is rimK

Identifier: 54293408

GI number: 54293408

Start: 500578

End: 501486

Strand: Direct

Name: rimK

Synonym: lpl0457

Alternate gene names: 54293408

Gene position: 500578-501486 (Clockwise)

Preceding gene: 54293407

Following gene: 54293410

Centisome position: 14.96

GC content: 40.92

Gene sequence:

>909_bases
ATGAAAATTGCGATATTGGCAACTAACCCCCATTTGTATTCTCATAAGCGTTTAAAGGCTGAGGCTGAGGCAGCGGGGCA
TGAGGTTAAAATTATTAACCCTTTATATTGTTATATGAACGTGGCTGCTTCTAATCCTAAGGTACATTATCGAGGTGGGG
CACCTTTACCGCATTTTGATGCCGTTATTCCTAGAATTGGCGCATCCATTACCTATTATGGTACGGCAGTATTGCGTCAT
ATGGAAACAATGGGCATGTACACTCTGAATGAATCCATAGCTATATCACGTTCCAGGGATAAATTTCGCTCTTTGCAATT
GCTGGCACGTAAAGGAATTCCTATGCCGTTAACCAGTTTTGCCCAGTCTCCTGATGATACTGAAGATTTGATTCATATGG
TTGGTGGGGCTCCTCTGGTCATAAAATTATTAGAAGGAACACAAGGCAAAGGAGTCATTCTTGCTGACAGTCATCAATCA
GCTGTGAGTATCATCAATGCTTTTAAAGAAATGCATGCCAATATTTTGGTCCAGGAATTCATTGAAGAATCCCGAGGTAC
GGATATACGTTGTTTTGTCATAGGAGAAAAAGTAGTTGCCGCAGTTAAACGGCAGGCCAAGGATGGGGAGTTTCGCGCAA
ATGTTCATCAAGGAGGAAAAGCAGTAAAAGTCAAACTTTCCCCGCAAGAACGGGCAATTGCTGTTAGTGCCGCAAAAACA
ATGGGATTAAGAGTTGCCGGAGTGGATCTGATTCGCTCAAATCATGGTCCATTAGTGCTAGAAATTAACTCTTCTCCAGG
TCTTGAAGGTATAGAAAAAGCGACTAATATTAATTTGGCAGGAAAAATCATTGAATACATTGAGAAAAAAGCAAAGCCAA
TTAGTTCCAATCATAGATTTCATGGATAA

Upstream 100 bases:

>100_bases
TGTTGTGATGCTTAAAACTTGCGTTATTTAATAGAAAATTAGGGAAAATGGTTTGGATTGTTCAGATTGAAGTATGAAAT
TACTGAGGAAAGTTTAATTC

Downstream 100 bases:

>100_bases
TTTCTAATGGGCTCCTGATTTGGAGTCACTTTTGCCAATTAGCCAATCCGCATTGACTTCCAGTTCCTGAGCTAATGTTT
TTAATACGGCTTCATCAGGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 302; Mature: 302

Protein sequence:

>302_residues
MKIAILATNPHLYSHKRLKAEAEAAGHEVKIINPLYCYMNVAASNPKVHYRGGAPLPHFDAVIPRIGASITYYGTAVLRH
METMGMYTLNESIAISRSRDKFRSLQLLARKGIPMPLTSFAQSPDDTEDLIHMVGGAPLVIKLLEGTQGKGVILADSHQS
AVSIINAFKEMHANILVQEFIEESRGTDIRCFVIGEKVVAAVKRQAKDGEFRANVHQGGKAVKVKLSPQERAIAVSAAKT
MGLRVAGVDLIRSNHGPLVLEINSSPGLEGIEKATNINLAGKIIEYIEKKAKPISSNHRFHG

Sequences:

>Translated_302_residues
MKIAILATNPHLYSHKRLKAEAEAAGHEVKIINPLYCYMNVAASNPKVHYRGGAPLPHFDAVIPRIGASITYYGTAVLRH
METMGMYTLNESIAISRSRDKFRSLQLLARKGIPMPLTSFAQSPDDTEDLIHMVGGAPLVIKLLEGTQGKGVILADSHQS
AVSIINAFKEMHANILVQEFIEESRGTDIRCFVIGEKVVAAVKRQAKDGEFRANVHQGGKAVKVKLSPQERAIAVSAAKT
MGLRVAGVDLIRSNHGPLVLEINSSPGLEGIEKATNINLAGKIIEYIEKKAKPISSNHRFHG
>Mature_302_residues
MKIAILATNPHLYSHKRLKAEAEAAGHEVKIINPLYCYMNVAASNPKVHYRGGAPLPHFDAVIPRIGASITYYGTAVLRH
METMGMYTLNESIAISRSRDKFRSLQLLARKGIPMPLTSFAQSPDDTEDLIHMVGGAPLVIKLLEGTQGKGVILADSHQS
AVSIINAFKEMHANILVQEFIEESRGTDIRCFVIGEKVVAAVKRQAKDGEFRANVHQGGKAVKVKLSPQERAIAVSAAKT
MGLRVAGVDLIRSNHGPLVLEINSSPGLEGIEKATNINLAGKIIEYIEKKAKPISSNHRFHG

Specific function: Responsible for the addition of glutamate residues to the C-terminus of ribosomal protein S6

COG id: COG0189

COG function: function code HJ; Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain

Homologues:

Organism=Homo sapiens, GI164663810, Length=220, Percent_Identity=32.7272727272727, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI134254462, Length=220, Percent_Identity=33.6363636363636, Blast_Score=103, Evalue=2e-22,
Organism=Escherichia coli, GI1787076, Length=291, Percent_Identity=60.4810996563574, Blast_Score=381, Evalue=1e-107,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RIMK_LEGPA (Q5X7X4)

Other databases:

- EMBL:   CR628336
- RefSeq:   YP_122819.1
- ProteinModelPortal:   Q5X7X4
- STRING:   Q5X7X4
- GeneID:   3118717
- GenomeReviews:   CR628336_GR
- KEGG:   lpp:lpp0481
- LegioList:   lpp0481
- eggNOG:   COG0189
- HOGENOM:   HBG679591
- OMA:   CREPRLY
- ProtClustDB:   CLSK832163
- BioCyc:   LPNE297246:LPP0481-MONOMER
- GO:   GO:0006412
- HAMAP:   MF_01552
- InterPro:   IPR011761
- InterPro:   IPR013651
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR004666
- Gene3D:   G3DSA:3.30.1490.20
- Gene3D:   G3DSA:3.30.470.20
- TIGRFAMs:   TIGR00768

Pfam domain/function: PF08443 RimK

EC number: NA

Molecular weight: Translated: 32882; Mature: 32882

Theoretical pI: Translated: 10.05; Mature: 10.05

Prosite motif: PS50975 ATP_GRASP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIAILATNPHLYSHKRLKAEAEAAGHEVKIINPLYCYMNVAASNPKVHYRGGAPLPHFD
CEEEEEECCCCHHHHHHHHHHHHHCCCEEEEECCEEEEEEEECCCCEEEECCCCCCCHHH
AVIPRIGASITYYGTAVLRHMETMGMYTLNESIAISRSRDKFRSLQLLARKGIPMPLTSF
HHHHHHCCEEEHHHHHHHHHHHHHCEEEECCCEEEECCHHHHHHHHHHHHCCCCCCHHHH
AQSPDDTEDLIHMVGGAPLVIKLLEGTQGKGVILADSHQSAVSIINAFKEMHANILVQEF
CCCCCCHHHHHHHHCCCCEEEEEECCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
IEESRGTDIRCFVIGEKVVAAVKRQAKDGEFRANVHQGGKAVKVKLSPQERAIAVSAAKT
HHHHCCCEEEEEEECHHHHHHHHHHCCCCCEEEEECCCCEEEEEEECCCHHEEEEEHHHH
MGLRVAGVDLIRSNHGPLVLEINSSPGLEGIEKATNINLAGKIIEYIEKKAKPISSNHRF
HCEEEECEEEEECCCCCEEEEECCCCCCCHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCC
HG
CC
>Mature Secondary Structure
MKIAILATNPHLYSHKRLKAEAEAAGHEVKIINPLYCYMNVAASNPKVHYRGGAPLPHFD
CEEEEEECCCCHHHHHHHHHHHHHCCCEEEEECCEEEEEEEECCCCEEEECCCCCCCHHH
AVIPRIGASITYYGTAVLRHMETMGMYTLNESIAISRSRDKFRSLQLLARKGIPMPLTSF
HHHHHHCCEEEHHHHHHHHHHHHHCEEEECCCEEEECCHHHHHHHHHHHHCCCCCCHHHH
AQSPDDTEDLIHMVGGAPLVIKLLEGTQGKGVILADSHQSAVSIINAFKEMHANILVQEF
CCCCCCHHHHHHHHCCCCEEEEEECCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
IEESRGTDIRCFVIGEKVVAAVKRQAKDGEFRANVHQGGKAVKVKLSPQERAIAVSAAKT
HHHHCCCEEEEEEECHHHHHHHHHHCCCCCEEEEECCCCEEEEEEECCCHHEEEEEHHHH
MGLRVAGVDLIRSNHGPLVLEINSSPGLEGIEKATNINLAGKIIEYIEKKAKPISSNHRF
HCEEEECEEEEECCCCCEEEEECCCCCCCHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCC
HG
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Glu; Ribosomal protein S6 [C]

Specific reaction: Catalyzes the addition of glutamic acids to the carboxyl end of ribosomal protein S6 [C]

General reaction: Ligases; Forming Carbon-Nitrogen Bonds; Acid-D-Amino-Acid Ligases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA