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The map label for this gene is secD

Identifier: 54020361

GI number: 54020361

Start: 165060

End: 167657

Strand: Reverse

Name: secD

Synonym: mhp139

Alternate gene names: 54020361

Gene position: 167657-165060 (Counterclockwise)

Preceding gene: 54020362

Following gene: 54020360

Centisome position: 18.78

GC content: 28.75

Gene sequence:

>2598_bases
ATGAAATTAGGTACTTTTTTTGCTAAGTTGTTTTCGCTTAATAGTTGAAAGCGCTTTTTTCTTGCTTTTTTGACTTTTGC
GCTTCTTGGAAGTGGGATTTTTTTGGTTTCAAATTTTTATATTTCTAAAAATATTAATCGTTCAATTGAATATGGTGGTG
GGGCTGAAGTTTTAGTTCAAGTTAAAACTTTAGATGGAAAAATTCCATCATCTAAAGTTGTAAAAGAAGCTGATGCAGCA
ATTTTTCAACGCCTAACTGGAGGAGCTAATCTTAGTGGGACAAGCGTTTTCACTGAAGGCGAAGGTCGGATTAGAATTTC
CCGTAATAAAATTTCTAATAATCGTGAATTAGACACTTTTATTCAAGAAATTGTTAATAAACCAGTTTTAACCATTACTG
ATGTTGATACAAATCCACTTTTTTTTGAAGGAAAATTTGATAAAAACCTTAAATTAGACCAGGGAAACGAAACAAATTGG
ATTGTTCCTTTTGCTCCAGGTTCTGCAATTTCACAACCAAATCCACAAAATCCGGCAAATAATCAAGTATTAATTGAGCT
AAAAGATAAAAAAGCTCAACTTGAGTGATCAAAAGCAACAGAGTATATTTCAAAATTAGGTCATGGTAAGAATCGAATTT
TGATTTGATCAAATATTGTTGAATTAAAAAAGATTGCAAAAGAAAAATTCCCTGCCCAATGAGCAAAATCCGGCGAAAAT
ATTTATAATTTTGTCCATGTTGGCGAGAAAACTACCCCTGAATTTCTTCAGGGCAATAAAATTTTACAACCAGAACTTAA
AAAATATCAATTTGATGCGAAAAAATATTTGATTTCCGATGCAACCGTTTCCCAAGCGCTAAATGGAAAATCCTTTGTAA
TTACTGGAAGATTTACCCCTCAAGAAGCAAAACAATTGGCCCTTGATATAAATTATGGAACAGCTGATTATAAACTAGAT
TTTTTATCAGCATCTTTTGTTAGCAAAACAAAATCAGATTCAGTTTTTATTGCGGGTTGAATTGCAATTGGGCTTGCAAT
TGCAATAATTTCTTTATTTTTGTTAATAAATTACGGGCTTTTAGGTGCGCTTGCAACAATTTCGCTTTCATTATATGTAT
TTCTAACATTACTTTTTTTCACAATTGTCAGAGGTGAATATTCGCCGATTACAATTTCAGCCTTAGTTGTGGGAATTGGA
ATGAATATTGATGCAAATGTTATTAGTTTTGAGGTATTTAAATCCCGAATTTATTCAGGAAATTCTGTTTTAAAAGCAAA
TTATCAAGCTAATCGATTGTCTTTTAATGCAATTCTTGATTCAAATATTACAACACTAATTGCAGCACTTGTTCTGTTCT
TTTTTGGTACTAAAAATGTTAAAAGTTTCTCGATTACTTTGATTTTTTCAATTATTTTCACTTTAATAGTAACAATCGGC
TTTACAAAATTTTTTACCAGCTTTATTCTTAAGGCAAACTTTTTCCAAAATAATGAAAAAAAACTTTGACTATTAGGTAT
CAAAAAATATTATCTTAGAAAATATCAACGCGGTTATAATTCAATTTATTCACAAATTGATTATGAAAAAATTTATAAAT
ATACGAGATGATTGCCGCTTATTTTGTTTTTAGGTTCAATAATAGTTTTTGCAGTTTTTGCCGGAATTTATAGATCATTT
GGTTCAGGATTTAATTTAGCAATTGATTTTAGTGGCGGAACTAACTTTTTAATTGAAAGCTCAAATTCAAGTTATGATTT
AATTACAAAGGAAAAAGCCGAAAAAATAATTAGTTTTCTTGATTCACAAAATATAAACAAGTCAAATTCAACAATTTTGC
TTAATCCATTAAATGAAAATGGAAATATTTTTAATCTTGAAATTAAAACAAAACTTGATCTAGCAACAAAAATTGCCTCA
TTAAATGCGGCAATCCAGAATAATTTTTCCAATATTCGAATGACAAATTATTCAATTTCGAATGAAGAAGCTCAAAAATT
AATTTTCAATGCAATTCTTTCAGTTGGAATCGCACTTATTTTTGTAACTATTTTTACGCTAATTAGGTTTAAATGGACTT
TTTCGCTTGCAATAATTTTCTCACTTCTTTTTAATGTTTTAATGGTTTTGCTAGCAATTATTATTACACGGATCGAAATA
TCGCAGAATTTAGTTGTTGCAATTCTTACTTTAATTGGTTATACAGTAAATGATACAATCGTGGTTTTTGATAGAGTAAA
AGCAAGATTTTCAGAAATAAATCATGAAAATGTTTATAAATTTGATAAAATTAAAGAAATTTCCTTACAAGCAATTAGAG
AAACAGCAAAAAGGTCGGTATATACATCCTTGACAACCATTTTAACAATTGTTGTTTTAATGATTTTTTATGAATCAATT
GATATTGTCTTTAGCCTGACGATGTTAATTGGTGTGATAATTGGAACATATTCCTCCTTATTTATCGCAACCCGCATTTG
GATTATTCTTGAATCATACCGTAATCGTAAAAAAGAGATGAGAATCAATAAAAAATACTGAAATGTCCAAAAAATTTATG
AACAAACTTTCGCAAATATTAATGATTATGAAAAATAA

Upstream 100 bases:

>100_bases
TTAATTAGCTTTCTTCTAACCTTTTCGTCAAAAAAACCATAAAAATACTTATTCATATTATTAAAATATGATATAATTGT
AAACTCGAGAAAGGAAAAGC

Downstream 100 bases:

>100_bases
TATAAATCAACTTTTTCTATTGTGGGGAAAATCAAAAATGTTGATTTTTTTCTAATATTTTATTTGATAACTTAAAAAAA
GGTAAAAAGTGAAAAAAAAG

Product: bifunctional preprotein translocase subunit SecD/SecF

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 865; Mature: 865

Protein sequence:

>865_residues
MKLGTFFAKLFSLNSWKRFFLAFLTFALLGSGIFLVSNFYISKNINRSIEYGGGAEVLVQVKTLDGKIPSSKVVKEADAA
IFQRLTGGANLSGTSVFTEGEGRIRISRNKISNNRELDTFIQEIVNKPVLTITDVDTNPLFFEGKFDKNLKLDQGNETNW
IVPFAPGSAISQPNPQNPANNQVLIELKDKKAQLEWSKATEYISKLGHGKNRILIWSNIVELKKIAKEKFPAQWAKSGEN
IYNFVHVGEKTTPEFLQGNKILQPELKKYQFDAKKYLISDATVSQALNGKSFVITGRFTPQEAKQLALDINYGTADYKLD
FLSASFVSKTKSDSVFIAGWIAIGLAIAIISLFLLINYGLLGALATISLSLYVFLTLLFFTIVRGEYSPITISALVVGIG
MNIDANVISFEVFKSRIYSGNSVLKANYQANRLSFNAILDSNITTLIAALVLFFFGTKNVKSFSITLIFSIIFTLIVTIG
FTKFFTSFILKANFFQNNEKKLWLLGIKKYYLRKYQRGYNSIYSQIDYEKIYKYTRWLPLILFLGSIIVFAVFAGIYRSF
GSGFNLAIDFSGGTNFLIESSNSSYDLITKEKAEKIISFLDSQNINKSNSTILLNPLNENGNIFNLEIKTKLDLATKIAS
LNAAIQNNFSNIRMTNYSISNEEAQKLIFNAILSVGIALIFVTIFTLIRFKWTFSLAIIFSLLFNVLMVLLAIIITRIEI
SQNLVVAILTLIGYTVNDTIVVFDRVKARFSEINHENVYKFDKIKEISLQAIRETAKRSVYTSLTTILTIVVLMIFYESI
DIVFSLTMLIGVIIGTYSSLFIATRIWIILESYRNRKKEMRINKKYWNVQKIYEQTFANINDYEK

Sequences:

>Translated_865_residues
MKLGTFFAKLFSLNS*KRFFLAFLTFALLGSGIFLVSNFYISKNINRSIEYGGGAEVLVQVKTLDGKIPSSKVVKEADAA
IFQRLTGGANLSGTSVFTEGEGRIRISRNKISNNRELDTFIQEIVNKPVLTITDVDTNPLFFEGKFDKNLKLDQGNETNW
IVPFAPGSAISQPNPQNPANNQVLIELKDKKAQLE*SKATEYISKLGHGKNRILI*SNIVELKKIAKEKFPAQ*AKSGEN
IYNFVHVGEKTTPEFLQGNKILQPELKKYQFDAKKYLISDATVSQALNGKSFVITGRFTPQEAKQLALDINYGTADYKLD
FLSASFVSKTKSDSVFIAG*IAIGLAIAIISLFLLINYGLLGALATISLSLYVFLTLLFFTIVRGEYSPITISALVVGIG
MNIDANVISFEVFKSRIYSGNSVLKANYQANRLSFNAILDSNITTLIAALVLFFFGTKNVKSFSITLIFSIIFTLIVTIG
FTKFFTSFILKANFFQNNEKKL*LLGIKKYYLRKYQRGYNSIYSQIDYEKIYKYTR*LPLILFLGSIIVFAVFAGIYRSF
GSGFNLAIDFSGGTNFLIESSNSSYDLITKEKAEKIISFLDSQNINKSNSTILLNPLNENGNIFNLEIKTKLDLATKIAS
LNAAIQNNFSNIRMTNYSISNEEAQKLIFNAILSVGIALIFVTIFTLIRFKWTFSLAIIFSLLFNVLMVLLAIIITRIEI
SQNLVVAILTLIGYTVNDTIVVFDRVKARFSEINHENVYKFDKIKEISLQAIRETAKRSVYTSLTTILTIVVLMIFYESI
DIVFSLTMLIGVIIGTYSSLFIATRIWIILESYRNRKKEMRINKKY*NVQKIYEQTFANINDYEK
>Mature_865_residues
MKLGTFFAKLFSLNS*KRFFLAFLTFALLGSGIFLVSNFYISKNINRSIEYGGGAEVLVQVKTLDGKIPSSKVVKEADAA
IFQRLTGGANLSGTSVFTEGEGRIRISRNKISNNRELDTFIQEIVNKPVLTITDVDTNPLFFEGKFDKNLKLDQGNETNW
IVPFAPGSAISQPNPQNPANNQVLIELKDKKAQLE*SKATEYISKLGHGKNRILI*SNIVELKKIAKEKFPAQ*AKSGEN
IYNFVHVGEKTTPEFLQGNKILQPELKKYQFDAKKYLISDATVSQALNGKSFVITGRFTPQEAKQLALDINYGTADYKLD
FLSASFVSKTKSDSVFIAG*IAIGLAIAIISLFLLINYGLLGALATISLSLYVFLTLLFFTIVRGEYSPITISALVVGIG
MNIDANVISFEVFKSRIYSGNSVLKANYQANRLSFNAILDSNITTLIAALVLFFFGTKNVKSFSITLIFSIIFTLIVTIG
FTKFFTSFILKANFFQNNEKKL*LLGIKKYYLRKYQRGYNSIYSQIDYEKIYKYTR*LPLILFLGSIIVFAVFAGIYRSF
GSGFNLAIDFSGGTNFLIESSNSSYDLITKEKAEKIISFLDSQNINKSNSTILLNPLNENGNIFNLEIKTKLDLATKIAS
LNAAIQNNFSNIRMTNYSISNEEAQKLIFNAILSVGIALIFVTIFTLIRFKWTFSLAIIFSLLFNVLMVLLAIIITRIEI
SQNLVVAILTLIGYTVNDTIVVFDRVKARFSEINHENVYKFDKIKEISLQAIRETAKRSVYTSLTTILTIVVLMIFYESI
DIVFSLTMLIGVIIGTYSSLFIATRIWIILESYRNRKKEMRINKKY*NVQKIYEQTFANINDYEK

Specific function: Required for efficient translocation of secretory pre- proteins under conditions of hypersecretion but is not required for the release of mature proteins from the membrane [H]

COG id: COG0342

COG function: function code U; Preprotein translocase subunit SecD

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the secD/secF family. SecF subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786610, Length=336, Percent_Identity=26.1904761904762, Blast_Score=108, Evalue=2e-24,
Organism=Escherichia coli, GI1786609, Length=197, Percent_Identity=31.4720812182741, Blast_Score=79, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005791
- InterPro:   IPR022813
- InterPro:   IPR022646
- InterPro:   IPR022645
- InterPro:   IPR005665 [H]

Pfam domain/function: PF07549 Sec_GG; PF02355 SecD_SecF [H]

EC number: NA

Molecular weight: Translated: 96175; Mature: 96175

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
0.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLGTFFAKLFSLNSKRFFLAFLTFALLGSGIFLVSNFYISKNINRSIEYGGGAEVLVQV
CCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEEEHEECCCCCCEECCCCCEEEEEE
KTLDGKIPSSKVVKEADAAIFQRLTGGANLSGTSVFTEGEGRIRISRNKISNNRELDTFI
EECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCEEEEECCCCCCCCHHHHHH
QEIVNKPVLTITDVDTNPLFFEGKFDKNLKLDQGNETNWIVPFAPGSAISQPNPQNPANN
HHHHCCCEEEEEECCCCCEEEECCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCC
QVLIELKDKKAQLESKATEYISKLGHGKNRILISNIVELKKIAKEKFPAQAKSGENIYNF
EEEEEECCHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHCCCCCCCCCCCEEE
VHVGEKTTPEFLQGNKILQPELKKYQFDAKKYLISDATVSQALNGKSFVITGRFTPQEAK
EECCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHCCCCEEEEEECCCHHHHH
QLALDINYGTADYKLDFLSASFVSKTKSDSVFIAGIAIGLAIAIISLFLLINYGLLGALA
HEEEEEECCCCCEEEEHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
TISLSLYVFLTLLFFTIVRGEYSPITISALVVGIGMNIDANVISFEVFKSRIYSGNSVLK
HHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHEEECCCCCCHHHHHHHHHHHHCCCCCEEE
ANYQANRLSFNAILDSNITTLIAALVLFFFGTKNVKSFSITLIFSIIFTLIVTIGFTKFF
ECCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
TSFILKANFFQNNEKKLLLGIKKYYLRKYQRGYNSIYSQIDYEKIYKYTRLPLILFLGSI
HHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
IVFAVFAGIYRSFGSGFNLAIDFSGGTNFLIESSNSSYDLITKEKAEKIISFLDSQNINK
HHHHHHHHHHHHHCCCCEEEEEECCCCEEEEECCCCCEEHHHHHHHHHHHHHHHCCCCCC
SNSTILLNPLNENGNIFNLEIKTKLDLATKIASLNAAIQNNFSNIRMTNYSISNEEAQKL
CCCEEEEEECCCCCCEEEEEEEEHHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHH
IFNAILSVGIALIFVTIFTLIRFKWTFSLAIIFSLLFNVLMVLLAIIITRIEISQNLVVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
ILTLIGYTVNDTIVVFDRVKARFSEINHENVYKFDKIKEISLQAIRETAKRSVYTSLTTI
HHHHHCCCCCCEEEEHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTIVVLMIFYESIDIVFSLTMLIGVIIGTYSSLFIATRIWIILESYRNRKKEMRINKKYN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCC
VQKIYEQTFANINDYEK
HHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MKLGTFFAKLFSLNSKRFFLAFLTFALLGSGIFLVSNFYISKNINRSIEYGGGAEVLVQV
CCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEEEHEECCCCCCEECCCCCEEEEEE
KTLDGKIPSSKVVKEADAAIFQRLTGGANLSGTSVFTEGEGRIRISRNKISNNRELDTFI
EECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCEEEEECCCCCCCCHHHHHH
QEIVNKPVLTITDVDTNPLFFEGKFDKNLKLDQGNETNWIVPFAPGSAISQPNPQNPANN
HHHHCCCEEEEEECCCCCEEEECCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCC
QVLIELKDKKAQLESKATEYISKLGHGKNRILISNIVELKKIAKEKFPAQAKSGENIYNF
EEEEEECCHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHCCCCCCCCCCCEEE
VHVGEKTTPEFLQGNKILQPELKKYQFDAKKYLISDATVSQALNGKSFVITGRFTPQEAK
EECCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHCCCCEEEEEECCCHHHHH
QLALDINYGTADYKLDFLSASFVSKTKSDSVFIAGIAIGLAIAIISLFLLINYGLLGALA
HEEEEEECCCCCEEEEHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
TISLSLYVFLTLLFFTIVRGEYSPITISALVVGIGMNIDANVISFEVFKSRIYSGNSVLK
HHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHEEECCCCCCHHHHHHHHHHHHCCCCCEEE
ANYQANRLSFNAILDSNITTLIAALVLFFFGTKNVKSFSITLIFSIIFTLIVTIGFTKFF
ECCCCCCEEEEEEECCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
TSFILKANFFQNNEKKLLLGIKKYYLRKYQRGYNSIYSQIDYEKIYKYTRLPLILFLGSI
HHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
IVFAVFAGIYRSFGSGFNLAIDFSGGTNFLIESSNSSYDLITKEKAEKIISFLDSQNINK
HHHHHHHHHHHHHCCCCEEEEEECCCCEEEEECCCCCEEHHHHHHHHHHHHHHHCCCCCC
SNSTILLNPLNENGNIFNLEIKTKLDLATKIASLNAAIQNNFSNIRMTNYSISNEEAQKL
CCCEEEEEECCCCCCEEEEEEEEHHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHH
IFNAILSVGIALIFVTIFTLIRFKWTFSLAIIFSLLFNVLMVLLAIIITRIEISQNLVVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
ILTLIGYTVNDTIVVFDRVKARFSEINHENVYKFDKIKEISLQAIRETAKRSVYTSLTTI
HHHHHCCCCCCEEEEHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTIVVLMIFYESIDIVFSLTMLIGVIIGTYSSLFIATRIWIILESYRNRKKEMRINKKYN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHCCCCCCC
VQKIYEQTFANINDYEK
HHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9694879; 9384377 [H]