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The map label for this gene is era

Identifier: 54020101

GI number: 54020101

Start: 253317

End: 254198

Strand: Direct

Name: era

Synonym: mhp226

Alternate gene names: 54020101

Gene position: 253317-254198 (Clockwise)

Preceding gene: 54020100

Following gene: 54020102

Centisome position: 28.37

GC content: 29.14

Gene sequence:

>882_bases
ATGGATATAAAAAAAACATGTTTTGTAGCAATTGTTGGTTTACCTAATGTTGGTAAGTCCTCACTTATAAATTCGCTTGT
GGAATTTCCAGTCTCAATTGTAAGTTTAAAGTCACAAACTACCCGCGATGCCATAAATGCAATTTATAATAAGGATAATC
TTCAAATTTTATTTGTCGATACTCCCGGCTTTCATATGCGAATTAATAATTTAAGTAATTCCTTAAATTATGCGATTAAC
TCAACACTTGAAGGAATTGATCTGGTCCTTTTTTTGCACCCGGTTGATAAACCAGTTGACCAAAATACTAGATTTTTGGC
AAAAAAAATTGCTAAAAATATGAATAAAATTGTTTTGATAACTAAAACTGACCTAGAAAATGATAAATTAAATTTTAAAA
TTCAGGAGAAAAATTTTCGTGAACTTAATTTTGAAAAAATTTTACCCTTTTCAACAAATTCAGAAGACTTACGTATTAAT
TTACTATTAGAAATTGAAAAGTTTGCTTATCCATCCGATCATTTTTATAGTAATTTGGATGTTACTGATCAAAGTTCACG
TTTTTTTGCCAAAGAAATTATTAGAAAACAAATACTTTTAAATCTTGAAGACGAAATCCCCCATCAAAGCGCAGTTTTAA
TTGATAATTTTGATGAATCGGATAACCGTTTTGTAAAAATTGAGGCAACAATTTATGTAGGAAAAAAATCACATTTACCA
ATAATAATTGGTAAGGGTGGTTCGGTTTTAGGAAAAATCGGAACAGATGCCCGTAGAGAACTTGAAGAGATTTTTGGCAA
AAAAGTTGTTCTAAAAAACCGCGTGTCTATAGCAAAAAAATGATTTAATAACCCTAAAATGATAAAAAGATTCGGGTATT
AA

Upstream 100 bases:

>100_bases
AGTTAGTATTTTTCTTTATAATTCCAAGTCAGAATTTAGGGAAAGAACATTAAATCAACTATTGCCAAACCAGTTTAACA
AGGATTTCTTTTAATAATTT

Downstream 100 bases:

>100_bases
GTCATTTTTATTTTATATTTTAATTAAATAAAATAAAGTTAGCAACTAAAATTGTTTTTGTTACTAACTTTATTTTATTT
AATTAGAAGGAAATAAATAT

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 293; Mature: 293

Protein sequence:

>293_residues
MDIKKTCFVAIVGLPNVGKSSLINSLVEFPVSIVSLKSQTTRDAINAIYNKDNLQILFVDTPGFHMRINNLSNSLNYAIN
STLEGIDLVLFLHPVDKPVDQNTRFLAKKIAKNMNKIVLITKTDLENDKLNFKIQEKNFRELNFEKILPFSTNSEDLRIN
LLLEIEKFAYPSDHFYSNLDVTDQSSRFFAKEIIRKQILLNLEDEIPHQSAVLIDNFDESDNRFVKIEATIYVGKKSHLP
IIIGKGGSVLGKIGTDARRELEEIFGKKVVLKNRVSIAKKWFNNPKMIKRFGY

Sequences:

>Translated_293_residues
MDIKKTCFVAIVGLPNVGKSSLINSLVEFPVSIVSLKSQTTRDAINAIYNKDNLQILFVDTPGFHMRINNLSNSLNYAIN
STLEGIDLVLFLHPVDKPVDQNTRFLAKKIAKNMNKIVLITKTDLENDKLNFKIQEKNFRELNFEKILPFSTNSEDLRIN
LLLEIEKFAYPSDHFYSNLDVTDQSSRFFAKEIIRKQILLNLEDEIPHQSAVLIDNFDESDNRFVKIEATIYVGKKSHLP
IIIGKGGSVLGKIGTDARRELEEIFGKKVVLKNRVSIAKK*FNNPKMIKRFGY
>Mature_293_residues
MDIKKTCFVAIVGLPNVGKSSLINSLVEFPVSIVSLKSQTTRDAINAIYNKDNLQILFVDTPGFHMRINNLSNSLNYAIN
STLEGIDLVLFLHPVDKPVDQNTRFLAKKIAKNMNKIVLITKTDLENDKLNFKIQEKNFRELNFEKILPFSTNSEDLRIN
LLLEIEKFAYPSDHFYSNLDVTDQSSRFFAKEIIRKQILLNLEDEIPHQSAVLIDNFDESDNRFVKIEATIYVGKKSHLP
IIIGKGGSVLGKIGTDARRELEEIFGKKVVLKNRVSIAKK*FNNPKMIKRFGY

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism [H]

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain [H]

Homologues:

Organism=Escherichia coli, GI1788919, Length=295, Percent_Identity=30.8474576271186, Blast_Score=132, Evalue=4e-32,
Organism=Drosophila melanogaster, GI24646434, Length=321, Percent_Identity=25.5451713395639, Blast_Score=75, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005662
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 33302; Mature: 33302

Theoretical pI: Translated: 9.84; Mature: 9.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIKKTCFVAIVGLPNVGKSSLINSLVEFPVSIVSLKSQTTRDAINAIYNKDNLQILFVD
CCCCCEEEEEEEECCCCCHHHHHHHHHHCCHHEEECCCHHHHHHHHHHCCCCCEEEEEEE
TPGFHMRINNLSNSLNYAINSTLEGIDLVLFLHPVDKPVDQNTRFLAKKIAKNMNKIVLI
CCCCEEEEECCCCCHHHHHCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHCCCCEEEEE
TKTDLENDKLNFKIQEKNFRELNFEKILPFSTNSEDLRINLLLEIEKFAYPSDHFYSNLD
EECCCCCCEEEEEECCCCCCCCCHHHCCCCCCCCCCEEEEEEEEEEHHCCCCCHHCCCCC
VTDQSSRFFAKEIIRKQILLNLEDEIPHQSAVLIDNFDESDNRFVKIEATIYVGKKSHLP
CCCCCHHHHHHHHHHHHHHCCCHHCCCCCCEEEEECCCCCCCEEEEEEEEEEECCCCCCC
IIIGKGGSVLGKIGTDARRELEEIFGKKVVLKNRVSIAKKFNNPKMIKRFGY
EEEECCCCEEEECCCHHHHHHHHHHCCEEEEHHHHHHHHHCCCHHHHHHCCC
>Mature Secondary Structure
MDIKKTCFVAIVGLPNVGKSSLINSLVEFPVSIVSLKSQTTRDAINAIYNKDNLQILFVD
CCCCCEEEEEEEECCCCCHHHHHHHHHHCCHHEEECCCHHHHHHHHHHCCCCCEEEEEEE
TPGFHMRINNLSNSLNYAINSTLEGIDLVLFLHPVDKPVDQNTRFLAKKIAKNMNKIVLI
CCCCEEEEECCCCCHHHHHCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHCCCCEEEEE
TKTDLENDKLNFKIQEKNFRELNFEKILPFSTNSEDLRINLLLEIEKFAYPSDHFYSNLD
EECCCCCCEEEEEECCCCCCCCCHHHCCCCCCCCCCEEEEEEEEEEHHCCCCCHHCCCCC
VTDQSSRFFAKEIIRKQILLNLEDEIPHQSAVLIDNFDESDNRFVKIEATIYVGKKSHLP
CCCCCHHHHHHHHHHHHHHCCCHHCCCCCCEEEEECCCCCCCEEEEEEEEEEECCCCCCC
IIIGKGGSVLGKIGTDARRELEEIFGKKVVLKNRVSIAKKFNNPKMIKRFGY
EEEECCCCEEEECCCHHHHHHHHHHCCEEEEHHHHHHHHHCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA