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The map label for this gene is cdd

Identifier: 54020100

GI number: 54020100

Start: 252915

End: 253310

Strand: Direct

Name: cdd

Synonym: mhp225

Alternate gene names: 54020100

Gene position: 252915-253310 (Clockwise)

Preceding gene: 54020099

Following gene: 54020101

Centisome position: 28.33

GC content: 32.07

Gene sequence:

>396_bases
ATGAAAAAAATTTTTTTAGAACTAGAAAAATTAAGTAAAAAAGCCTACTGTCCTTATTCAGATTTTGCCGTTGCTGCAAT
TTTAGTGACTACTTCTGGCCAATTTTTTAAAGGCGTAAATGTTGAAAATGCCGTTTTTCCCGCAACAATTTGTGCTGAAA
GGGTTGCAATAACCCAGGCAATTGCAAGCGGAATTGAACCTAAAACTTTCAAAGAAATTCACATTTATAGCCCAAATACA
GATAAATTCATTATCCCTTGTGGTCAGTGTTTGCAAGTTTGCGCTGAATTTTTTTCAGAAAAAGTTAGTATTTTTCTTTA
TAATTCCAAGTCAGAATTTAGGGAAAGAACATTAAATCAACTATTGCCAAACCAGTTTAACAAGGATTTCTTTTAA

Upstream 100 bases:

>100_bases
TCTATCATTTGCTTGGCTTTGATCACCAGGATGAAAAAACAAATAAGTTAATGGATGAAAAAGTTGAAAATATTTTAATA
AATTTAGGAATTAATCGATA

Downstream 100 bases:

>100_bases
TAATTTATGGATATAAAAAAAACATGTTTTGTAGCAATTGTTGGTTTACCTAATGTTGGTAAGTCCTCACTTATAAATTC
GCTTGTGGAATTTCCAGTCT

Product: cytidine deaminase

Products: NA

Alternate protein names: CDA; Cytidine aminohydrolase [H]

Number of amino acids: Translated: 131; Mature: 131

Protein sequence:

>131_residues
MKKIFLELEKLSKKAYCPYSDFAVAAILVTTSGQFFKGVNVENAVFPATICAERVAITQAIASGIEPKTFKEIHIYSPNT
DKFIIPCGQCLQVCAEFFSEKVSIFLYNSKSEFRERTLNQLLPNQFNKDFF

Sequences:

>Translated_131_residues
MKKIFLELEKLSKKAYCPYSDFAVAAILVTTSGQFFKGVNVENAVFPATICAERVAITQAIASGIEPKTFKEIHIYSPNT
DKFIIPCGQCLQVCAEFFSEKVSIFLYNSKSEFRERTLNQLLPNQFNKDFF
>Mature_131_residues
MKKIFLELEKLSKKAYCPYSDFAVAAILVTTSGQFFKGVNVENAVFPATICAERVAITQAIASGIEPKTFKEIHIYSPNT
DKFIIPCGQCLQVCAEFFSEKVSIFLYNSKSEFRERTLNQLLPNQFNKDFF

Specific function: This enzyme scavenge exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis [H]

COG id: COG0295

COG function: function code F; Cytidine deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI11386157, Length=129, Percent_Identity=39.5348837209302, Blast_Score=100, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17540514, Length=92, Percent_Identity=43.4782608695652, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17551074, Length=114, Percent_Identity=41.2280701754386, Blast_Score=74, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6323274, Length=129, Percent_Identity=34.8837209302326, Blast_Score=72, Evalue=4e-14,
Organism=Drosophila melanogaster, GI24582741, Length=132, Percent_Identity=38.6363636363636, Blast_Score=86, Evalue=6e-18,
Organism=Drosophila melanogaster, GI19920920, Length=98, Percent_Identity=38.7755102040816, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24582744, Length=92, Percent_Identity=36.9565217391304, Blast_Score=68, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002125
- InterPro:   IPR006262
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: =3.5.4.5 [H]

Molecular weight: Translated: 14866; Mature: 14866

Theoretical pI: Translated: 8.20; Mature: 8.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.8 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
3.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIFLELEKLSKKAYCPYSDFAVAAILVTTSGQFFKGVNVENAVFPATICAERVAITQA
CCHHHHHHHHHHHHCCCCCCHHHHHHHHEECCCCCEECCCCCCCHHHHHHHHHHHHHHHH
IASGIEPKTFKEIHIYSPNTDKFIIPCGQCLQVCAEFFSEKVSIFLYNSKSEFRERTLNQ
HHCCCCCCCEEEEEEECCCCCEEEECHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHH
LLPNQFNKDFF
HHHHCCCCCCC
>Mature Secondary Structure
MKKIFLELEKLSKKAYCPYSDFAVAAILVTTSGQFFKGVNVENAVFPATICAERVAITQA
CCHHHHHHHHHHHHCCCCCCHHHHHHHHEECCCCCEECCCCCCCHHHHHHHHHHHHHHHH
IASGIEPKTFKEIHIYSPNTDKFIIPCGQCLQVCAEFFSEKVSIFLYNSKSEFRERTLNQ
HHCCCCCCCEEEEEEECCCCCEEEECHHHHHHHHHHHHHCCEEEEEECCHHHHHHHHHHH
LLPNQFNKDFF
HHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11739901 [H]