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The map label for this gene is murB

Identifier: 52842819

GI number: 52842819

Start: 2948810

End: 2949748

Strand: Reverse

Name: murB

Synonym: lpg2613

Alternate gene names: 52842819

Gene position: 2949748-2948810 (Counterclockwise)

Preceding gene: 52842820

Following gene: 52842818

Centisome position: 86.81

GC content: 43.98

Gene sequence:

>939_bases
GTGAGAATGAACATGAGCATAACGGGAATGGACAGCAGTCATGTAACAGAGTCTCAGGGCACTTTGCTTTTCAATGAGCC
TTTGGCTGAGTATACTACCTGGCGAGTTGGTGGCCCTGCAGCGAGGCTTTATAAACCAGCAAATATAGATGATTTGGCTT
TGTTTTTAAGTCGATTGCCTTTTGATGAGCCATTATTATGGTTAGGTTTAGGCTCTAATTCTCTAATTCGCGATGGCGGT
TTTTCCGGTACCGTGATTCTCACTCAGGGCTGTTTAAAAGAAATGACCCTATTGAGCGATAACTGTATTCGGGTTGAGGC
AGGGGTATCCTGTGCCAGTATGGCTCGTTTTTCTGCGCGTAATAATCTGTCAGGAGGAGAGTTTTGGGCTGGTATCCCCG
GTACCATGGGTGGTGCTCTGCGAATGAATGCCGGTTGTCATGGAGGTGAAACCTGGCAGTCGGTTATTGAAGTACAAACG
ATAAATCGTCGAGGTGAAATCAGAACCCGTAAACCGGAAGAATTTGAAGTGGCTTATCGACATGTTGCTGGCTTGGGAGA
TGAATGGTTTATTTCCGCAAAGCTTCAGCTATCACCAGGTAATAAAGAGACATCCTTGCAATTAATTAAGGATTTATTGG
CTCATAGAGCCAAGACCCAACCAACTAATGAATATAATTGTGGGTCGGTATTTAGAAACCCTCCTGGAGATTTTGCAGCG
CGACTTATTGAATCTTGTGGCCTCAAGGGGGTAAGCATTGGTGGGGCAGTTGTTTCTGAAAAACATGCCAATTTTATTAT
CAATCATCAAGGTACTGCCACGGCAGCTAATATTGAAGCCTTGATTCATTTGGTGCAAACTAAAGTTCGAGAGCAAACAT
CTATAGAGTTGATACGCGAAGTACATATCATTGGAGACGCTAATGTCCAAACCCGTTAA

Upstream 100 bases:

>100_bases
TGAAAGCCACCTTAGATGAATTTATTAAAGATGGTGACGTTATTTTGATGCAGGGAGCTGGAAGTATCGGCCAAATAGCA
GTGAACCTGATGAAAAACAT

Downstream 100 bases:

>100_bases
TTTGGTTTTACTTTATGGTGGAAAATCAGGCGAGCATGAAGTGTCATTGGTTTCTGCCGCATCGGTTCTAAAACACCTGG
ATTCCGAGAAATATCATATT

Product: UDP-N-acetylenolpyruvoylglucosamine reductase

Products: NA

Alternate protein names: UDP-N-acetylmuramate dehydrogenase [H]

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MRMNMSITGMDSSHVTESQGTLLFNEPLAEYTTWRVGGPAARLYKPANIDDLALFLSRLPFDEPLLWLGLGSNSLIRDGG
FSGTVILTQGCLKEMTLLSDNCIRVEAGVSCASMARFSARNNLSGGEFWAGIPGTMGGALRMNAGCHGGETWQSVIEVQT
INRRGEIRTRKPEEFEVAYRHVAGLGDEWFISAKLQLSPGNKETSLQLIKDLLAHRAKTQPTNEYNCGSVFRNPPGDFAA
RLIESCGLKGVSIGGAVVSEKHANFIINHQGTATAANIEALIHLVQTKVREQTSIELIREVHIIGDANVQTR

Sequences:

>Translated_312_residues
MRMNMSITGMDSSHVTESQGTLLFNEPLAEYTTWRVGGPAARLYKPANIDDLALFLSRLPFDEPLLWLGLGSNSLIRDGG
FSGTVILTQGCLKEMTLLSDNCIRVEAGVSCASMARFSARNNLSGGEFWAGIPGTMGGALRMNAGCHGGETWQSVIEVQT
INRRGEIRTRKPEEFEVAYRHVAGLGDEWFISAKLQLSPGNKETSLQLIKDLLAHRAKTQPTNEYNCGSVFRNPPGDFAA
RLIESCGLKGVSIGGAVVSEKHANFIINHQGTATAANIEALIHLVQTKVREQTSIELIREVHIIGDANVQTR
>Mature_312_residues
MRMNMSITGMDSSHVTESQGTLLFNEPLAEYTTWRVGGPAARLYKPANIDDLALFLSRLPFDEPLLWLGLGSNSLIRDGG
FSGTVILTQGCLKEMTLLSDNCIRVEAGVSCASMARFSARNNLSGGEFWAGIPGTMGGALRMNAGCHGGETWQSVIEVQT
INRRGEIRTRKPEEFEVAYRHVAGLGDEWFISAKLQLSPGNKETSLQLIKDLLAHRAKTQPTNEYNCGSVFRNPPGDFAA
RLIESCGLKGVSIGGAVVSEKHANFIINHQGTATAANIEALIHLVQTKVREQTSIELIREVHIIGDANVQTR

Specific function: Cell wall formation [H]

COG id: COG0812

COG function: function code M; UDP-N-acetylmuramate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR003170
- InterPro:   IPR011601
- InterPro:   IPR006094 [H]

Pfam domain/function: PF01565 FAD_binding_4; PF02873 MurB_C [H]

EC number: =1.1.1.158 [H]

Molecular weight: Translated: 33982; Mature: 33982

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRMNMSITGMDSSHVTESQGTLLFNEPLAEYTTWRVGGPAARLYKPANIDDLALFLSRLP
CCEEEEEECCCCCCCCCCCCCEEECCCHHHHHEEECCCCHHHHCCCCCHHHHHHHHHHCC
FDEPLLWLGLGSNSLIRDGGFSGTVILTQGCLKEMTLLSDNCIRVEAGVSCASMARFSAR
CCCCEEEEECCCCCEEECCCCCCEEEEEHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHC
NNLSGGEFWAGIPGTMGGALRMNAGCHGGETWQSVIEVQTINRRGEIRTRKPEEFEVAYR
CCCCCCCEEECCCCCCCCCEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHH
HVAGLGDEWFISAKLQLSPGNKETSLQLIKDLLAHRAKTQPTNEYNCGSVFRNPPGDFAA
HHHCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHH
RLIESCGLKGVSIGGAVVSEKHANFIINHQGTATAANIEALIHLVQTKVREQTSIELIRE
HHHHHCCCCCEECCCHHEECCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VHIIGDANVQTR
HHEEECCCCCCC
>Mature Secondary Structure
MRMNMSITGMDSSHVTESQGTLLFNEPLAEYTTWRVGGPAARLYKPANIDDLALFLSRLP
CCEEEEEECCCCCCCCCCCCCEEECCCHHHHHEEECCCCHHHHCCCCCHHHHHHHHHHCC
FDEPLLWLGLGSNSLIRDGGFSGTVILTQGCLKEMTLLSDNCIRVEAGVSCASMARFSAR
CCCCEEEEECCCCCEEECCCCCCEEEEEHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHC
NNLSGGEFWAGIPGTMGGALRMNAGCHGGETWQSVIEVQTINRRGEIRTRKPEEFEVAYR
CCCCCCCEEECCCCCCCCCEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHH
HVAGLGDEWFISAKLQLSPGNKETSLQLIKDLLAHRAKTQPTNEYNCGSVFRNPPGDFAA
HHHCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHH
RLIESCGLKGVSIGGAVVSEKHANFIINHQGTATAANIEALIHLVQTKVREQTSIELIRE
HHHHHCCCCCEECCCHHEECCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VHIIGDANVQTR
HHEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA