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The map label for this gene is yycF [H]

Identifier: 52788011

GI number: 52788011

Start: 4186065

End: 4186772

Strand: Reverse

Name: yycF [H]

Synonym: BLi04335

Alternate gene names: 52788011

Gene position: 4186772-4186065 (Counterclockwise)

Preceding gene: 52788012

Following gene: 52788010

Centisome position: 99.15

GC content: 47.03

Gene sequence:

>708_bases
ATGGAAAAAAAGATACTAGTTGTAGATGATGAAAAGCCGATTGCTGATATTTTAGAGTTTAATCTGAAAAAAGAGGGCTA
TGAAGTCCATTGCGCATACGACGGCAATGAAGCGCTTCAGATGGTTGAGGATCTCAACCCTGATATGATTCTGCTCGACA
TCATGCTTCCGAATAAAGACGGTGTGGAAGTGTGCCGTGAAGTCCGCAAAAAATATGATATGCCCATCATTATGCTGACA
GCAAAGGATTCGGAAATCGATAAAGTCATCGGCCTTGAACTGGGCGCTGACGATTATGTGACAAAACCGTTCAGCACCCG
CGAACTGCTGGCGCGTGTCAAAGCGAACCTGAGAAGACAGAACACAGCGGCTCCTGCCGAAGAAGAATCGTCTTCAAACG
AAATTCAAATCGGATCGCTCGTCATTTTTCCGGATGCCTATGTCGTTTCAAAACGCGACGAGACAATCGAGCTGACACAT
CGGGAATTCGAACTGCTGCATTACCTTGCAAAACATATCGGGCAAGTCATGACGCGTGAACATCTTCTGCAAACCGTGTG
GGGATACGACTACTTTGGGGATGTCCGGACAGTTGACGTTACGGTTAGACGCCTTCGCGAAAAAATCGAGGATAATCCGA
GTCACCCAAGCTGGATCGTTACAAGGCGCGGTGTCGGCTACTATTTGAGAAATCCGGAACAGGACTAA

Upstream 100 bases:

>100_bases
GAAAGTGTTTTTTTAATGATGACATGCAGTGTACTTTGATATAAAACATAGACAGCCATCCGCTGGCTGTATCCAAACTC
TGAACCAGGAGGAATGAATA

Downstream 100 bases:

>100_bases
TACACAAATGAATAAAGTAAGTTTTTTTCGCTCGATTCATTTTAAGTTTACCTTAATATACGTTCTGCTGATTATCGTCG
CCATGCAGATTATCGGCGTC

Product: YycF

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 235; Mature: 235

Protein sequence:

>235_residues
MEKKILVVDDEKPIADILEFNLKKEGYEVHCAYDGNEALQMVEDLNPDMILLDIMLPNKDGVEVCREVRKKYDMPIIMLT
AKDSEIDKVIGLELGADDYVTKPFSTRELLARVKANLRRQNTAAPAEEESSSNEIQIGSLVIFPDAYVVSKRDETIELTH
REFELLHYLAKHIGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPSWIVTRRGVGYYLRNPEQD

Sequences:

>Translated_235_residues
MEKKILVVDDEKPIADILEFNLKKEGYEVHCAYDGNEALQMVEDLNPDMILLDIMLPNKDGVEVCREVRKKYDMPIIMLT
AKDSEIDKVIGLELGADDYVTKPFSTRELLARVKANLRRQNTAAPAEEESSSNEIQIGSLVIFPDAYVVSKRDETIELTH
REFELLHYLAKHIGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPSWIVTRRGVGYYLRNPEQD
>Mature_235_residues
MEKKILVVDDEKPIADILEFNLKKEGYEVHCAYDGNEALQMVEDLNPDMILLDIMLPNKDGVEVCREVRKKYDMPIIMLT
AKDSEIDKVIGLELGADDYVTKPFSTRELLARVKANLRRQNTAAPAEEESSSNEIQIGSLVIFPDAYVVSKRDETIELTH
REFELLHYLAKHIGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPSWIVTRRGVGYYLRNPEQD

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH, ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF. Binds to the ftsAZ P1 promoter seque

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=225, Percent_Identity=37.7777777777778, Blast_Score=169, Evalue=1e-43,
Organism=Escherichia coli, GI1786599, Length=230, Percent_Identity=40.4347826086956, Blast_Score=168, Evalue=3e-43,
Organism=Escherichia coli, GI2367329, Length=227, Percent_Identity=41.8502202643172, Blast_Score=167, Evalue=7e-43,
Organism=Escherichia coli, GI1788394, Length=225, Percent_Identity=39.1111111111111, Blast_Score=154, Evalue=5e-39,
Organism=Escherichia coli, GI87082012, Length=224, Percent_Identity=37.0535714285714, Blast_Score=150, Evalue=8e-38,
Organism=Escherichia coli, GI1786784, Length=231, Percent_Identity=39.3939393939394, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI145693140, Length=228, Percent_Identity=36.8421052631579, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI1790860, Length=233, Percent_Identity=38.1974248927039, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI1790863, Length=232, Percent_Identity=35.7758620689655, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1786911, Length=224, Percent_Identity=34.375, Blast_Score=137, Evalue=6e-34,
Organism=Escherichia coli, GI1787229, Length=230, Percent_Identity=34.3478260869565, Blast_Score=137, Evalue=6e-34,
Organism=Escherichia coli, GI1789402, Length=227, Percent_Identity=32.5991189427313, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI1790552, Length=233, Percent_Identity=33.0472103004292, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1787375, Length=226, Percent_Identity=32.7433628318584, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI1788550, Length=119, Percent_Identity=37.8151260504202, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI1790299, Length=116, Percent_Identity=32.7586206896552, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1787487, Length=102, Percent_Identity=29.4117647058824, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1790437, Length=114, Percent_Identity=33.3333333333333, Blast_Score=61, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 27166; Mature: 27166

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKKILVVDDEKPIADILEFNLKKEGYEVHCAYDGNEALQMVEDLNPDMILLDIMLPNKD
CCCCEEEEECCCCHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHCCCCEEEEEEEECCCC
GVEVCREVRKKYDMPIIMLTAKDSEIDKVIGLELGADDYVTKPFSTRELLARVKANLRRQ
HHHHHHHHHHHCCCCEEEEEECCCCHHHHEEEEECCCCCCCCCCCHHHHHHHHHHHHHHC
NTAAPAEEESSSNEIQIGSLVIFPDAYVVSKRDETIELTHREFELLHYLAKHIGQVMTRE
CCCCCCCCCCCCCCEEEEEEEEECCEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHH
HLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPSWIVTRRGVGYYLRNPEQD
HHHHHHHCCCCCCCCEEHHHHHHHHHHHHHCCCCCCCEEEEECCCEEEECCCCCC
>Mature Secondary Structure
MEKKILVVDDEKPIADILEFNLKKEGYEVHCAYDGNEALQMVEDLNPDMILLDIMLPNKD
CCCCEEEEECCCCHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHCCCCEEEEEEEECCCC
GVEVCREVRKKYDMPIIMLTAKDSEIDKVIGLELGADDYVTKPFSTRELLARVKANLRRQ
HHHHHHHHHHHCCCCEEEEEECCCCHHHHEEEEECCCCCCCCCCCHHHHHHHHHHHHHHC
NTAAPAEEESSSNEIQIGSLVIFPDAYVVSKRDETIELTHREFELLHYLAKHIGQVMTRE
CCCCCCCCCCCCCCEEEEEEEEECCEEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHH
HLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPSWIVTRRGVGYYLRNPEQD
HHHHHHHCCCCCCCCEEHHHHHHHHHHHHHCCCCCCCEEEEECCCEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 9829949; 10878122 [H]