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The map label for this gene is yycG [H]

Identifier: 52788010

GI number: 52788010

Start: 4184213

End: 4186057

Strand: Reverse

Name: yycG [H]

Synonym: BLi04334

Alternate gene names: 52788010

Gene position: 4186057-4184213 (Counterclockwise)

Preceding gene: 52788011

Following gene: 52788009

Centisome position: 99.13

GC content: 44.34

Gene sequence:

>1845_bases
ATGAATAAAGTAAGTTTTTTTCGCTCGATTCATTTTAAGTTTACCTTAATATACGTTCTGCTGATTATCGTCGCCATGCA
GATTATCGGCGTCTACTTTGTCAATGAGATGGAGAAGTCACTTCTTAAATCATATAATGACTCTCTTGATCAGCGGGTGA
ACAACCTATCGTATTATCTGGAACAGGAAATGACGAAGGATAGAAGCACATCTTCCTCGTCTACCTTGAAGGAAGATGCA
GAGCGGATTCTAAATGATTTCAGCAAAGAAGGCGAAATTCTCGAAGTCAGTCTGATTGATAAAAGCTATGAAGTCATCGC
GACCTCCAATCCTTATAACCGGGAGGTGGCGGGGAAAAAGACAACAGAGGGCATTATCAAAAGGACGCTGCTTGTCGGCA
TTCCATACGAAAATAAATTTTTCGACCCGGAGCGGGACAGCAAAGTGCGGATTTCGGTCACACCGATTAAAAAATCGAAT
CAAGAGACAATCGGGGCCATTTACGTCGTGGCATCGATGGATAATGTCTACAATCAAATCCGGACGATCAACACCATTTT
AGCGTCTGGAACTTTTATTGCGCTTGGAATCACTGCTTTTCTCGGGATTTTTGTCGCGCGAACGATTACACATCCGCTGT
CAGATATGAGAAAACAGGCCATTGAACTGGCGAAAGGAAATTTCTCAAGAAAAGTCAGGAAGTACGGAAACGACGAAATC
GGCCAGCTGGCCACAACGTTTAATTATTTAACAAGAGAGCTGAAAGAAGCTCAGTCCATGACAGAAGGCGAACGAAAAAA
ACTATCTTCTGTTATTGCGTATATGACAGACGGAGTTATCGCGACTAACCGAAATGGCGCGATTATTTTGCTTAATACGC
CGGCGCTGGAGCTTCTAAATGTTTCACGTGAAACGGCTCTTGAAATGCCGATCACTTCGCTGCTCGGCCTTGAAGACGAA
TACACGTTTGAAGATTTGGTTGAACAGCAGGATTCCCTGCTTCTTGAAATTGAACAGGAAGAACGGACGTCTGTGCTCCG
CGTCAATTTCTCGGTCATCCAAAAAGAACACGGAAAGATCGACGGATTGATTGCGGTCATTTACGATGTCACAGAACAAG
AGCAGATCGATCAAGAGCGGAGAGAGTTTGTTGCAAATGTCTCCCACGAGCTCAGAACGCCGCTCACAACGATGCGAAGC
TACCTAGAAGCGCTTGCGGAAGGGGCATGGCAGGATCCAAACATTGCGCCGCGCTTCTTGAATGTGACACAGAATGAAAC
AGAGCGCATGATCAGGCTTGTCAACGACCTGCTGCAGCTTTCAAAGTTTGATAGCAAAGATTATCAATTCAATAAAGAAT
GGATTCATTTTATCCGTTTCTTCTCATTGATTATTGAACGCTTTGAAATGACGAAAGAGCAGCATGTTGAGTTTATCAGC
AATCTGCCGGATAGAGAATTGTATGTTGAAATCGATCCGGACAAGATTACGCAAGTGCTGGATAATATCATTTCAAATGC
ATTGAAATATTCCCCTGAAGGAGGCCATATCACGTTCTCTGTTGATGTAAATGAAGAAGAAGAGCTTCTTTATGTCAGTG
TCAAAGACGAAGGTGTCGGCATTCCGAGAAAAGACGTGGAGAAGATCTTCGAGCGGTTCTACCGTGTAGATAAAGCCAGA
ACAAGAAGACTCGGCGGTACGGGACTCGGTCTTGCGATCGCAAAAGAAATGGTACAAGCCCATAGCGGCGACATCTGGGC
CGACAGCATCGAAGGAAAAGGAACAACGATCACATTTACCCTGCCGTATAAAGAAGAACAAGAGGATGATTGGGATGAAG
CGTGA

Upstream 100 bases:

>100_bases
CGCGAAAAAATCGAGGATAATCCGAGTCACCCAAGCTGGATCGTTACAAGGCGCGGTGTCGGCTACTATTTGAGAAATCC
GGAACAGGACTAATACACAA

Downstream 100 bases:

>100_bases
AACAATTAAAACGATAATACTGTCCCTTTTGGTTTTGATCAGTCTTCTTTTTACTTTTAATATTTGGGGATTTCAGGGGA
ATTACGAAAAAGTTGAAGAC

Product: YycG

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 614; Mature: 614

Protein sequence:

>614_residues
MNKVSFFRSIHFKFTLIYVLLIIVAMQIIGVYFVNEMEKSLLKSYNDSLDQRVNNLSYYLEQEMTKDRSTSSSSTLKEDA
ERILNDFSKEGEILEVSLIDKSYEVIATSNPYNREVAGKKTTEGIIKRTLLVGIPYENKFFDPERDSKVRISVTPIKKSN
QETIGAIYVVASMDNVYNQIRTINTILASGTFIALGITAFLGIFVARTITHPLSDMRKQAIELAKGNFSRKVRKYGNDEI
GQLATTFNYLTRELKEAQSMTEGERKKLSSVIAYMTDGVIATNRNGAIILLNTPALELLNVSRETALEMPITSLLGLEDE
YTFEDLVEQQDSLLLEIEQEERTSVLRVNFSVIQKEHGKIDGLIAVIYDVTEQEQIDQERREFVANVSHELRTPLTTMRS
YLEALAEGAWQDPNIAPRFLNVTQNETERMIRLVNDLLQLSKFDSKDYQFNKEWIHFIRFFSLIIERFEMTKEQHVEFIS
NLPDRELYVEIDPDKITQVLDNIISNALKYSPEGGHITFSVDVNEEEELLYVSVKDEGVGIPRKDVEKIFERFYRVDKAR
TRRLGGTGLGLAIAKEMVQAHSGDIWADSIEGKGTTITFTLPYKEEQEDDWDEA

Sequences:

>Translated_614_residues
MNKVSFFRSIHFKFTLIYVLLIIVAMQIIGVYFVNEMEKSLLKSYNDSLDQRVNNLSYYLEQEMTKDRSTSSSSTLKEDA
ERILNDFSKEGEILEVSLIDKSYEVIATSNPYNREVAGKKTTEGIIKRTLLVGIPYENKFFDPERDSKVRISVTPIKKSN
QETIGAIYVVASMDNVYNQIRTINTILASGTFIALGITAFLGIFVARTITHPLSDMRKQAIELAKGNFSRKVRKYGNDEI
GQLATTFNYLTRELKEAQSMTEGERKKLSSVIAYMTDGVIATNRNGAIILLNTPALELLNVSRETALEMPITSLLGLEDE
YTFEDLVEQQDSLLLEIEQEERTSVLRVNFSVIQKEHGKIDGLIAVIYDVTEQEQIDQERREFVANVSHELRTPLTTMRS
YLEALAEGAWQDPNIAPRFLNVTQNETERMIRLVNDLLQLSKFDSKDYQFNKEWIHFIRFFSLIIERFEMTKEQHVEFIS
NLPDRELYVEIDPDKITQVLDNIISNALKYSPEGGHITFSVDVNEEEELLYVSVKDEGVGIPRKDVEKIFERFYRVDKAR
TRRLGGTGLGLAIAKEMVQAHSGDIWADSIEGKGTTITFTLPYKEEQEDDWDEA
>Mature_614_residues
MNKVSFFRSIHFKFTLIYVLLIIVAMQIIGVYFVNEMEKSLLKSYNDSLDQRVNNLSYYLEQEMTKDRSTSSSSTLKEDA
ERILNDFSKEGEILEVSLIDKSYEVIATSNPYNREVAGKKTTEGIIKRTLLVGIPYENKFFDPERDSKVRISVTPIKKSN
QETIGAIYVVASMDNVYNQIRTINTILASGTFIALGITAFLGIFVARTITHPLSDMRKQAIELAKGNFSRKVRKYGNDEI
GQLATTFNYLTRELKEAQSMTEGERKKLSSVIAYMTDGVIATNRNGAIILLNTPALELLNVSRETALEMPITSLLGLEDE
YTFEDLVEQQDSLLLEIEQEERTSVLRVNFSVIQKEHGKIDGLIAVIYDVTEQEQIDQERREFVANVSHELRTPLTTMRS
YLEALAEGAWQDPNIAPRFLNVTQNETERMIRLVNDLLQLSKFDSKDYQFNKEWIHFIRFFSLIIERFEMTKEQHVEFIS
NLPDRELYVEIDPDKITQVLDNIISNALKYSPEGGHITFSVDVNEEEELLYVSVKDEGVGIPRKDVEKIFERFYRVDKAR
TRRLGGTGLGLAIAKEMVQAHSGDIWADSIEGKGTTITFTLPYKEEQEDDWDEA

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH and ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF [H]

COG id: COG5002

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=240, Percent_Identity=37.5, Blast_Score=148, Evalue=1e-36,
Organism=Escherichia coli, GI1788393, Length=234, Percent_Identity=32.9059829059829, Blast_Score=130, Evalue=4e-31,
Organism=Escherichia coli, GI1788549, Length=385, Percent_Identity=27.7922077922078, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI145693157, Length=241, Percent_Identity=29.8755186721992, Blast_Score=117, Evalue=3e-27,
Organism=Escherichia coli, GI1788713, Length=234, Percent_Identity=28.6324786324786, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1790346, Length=237, Percent_Identity=31.2236286919831, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI48994928, Length=273, Percent_Identity=29.3040293040293, Blast_Score=107, Evalue=3e-24,
Organism=Escherichia coli, GI1786783, Length=233, Percent_Identity=30.9012875536481, Blast_Score=105, Evalue=8e-24,
Organism=Escherichia coli, GI1786912, Length=247, Percent_Identity=31.1740890688259, Blast_Score=102, Evalue=9e-23,
Organism=Escherichia coli, GI1790436, Length=233, Percent_Identity=31.7596566523605, Blast_Score=99, Evalue=1e-21,
Organism=Escherichia coli, GI1789149, Length=234, Percent_Identity=29.9145299145299, Blast_Score=97, Evalue=4e-21,
Organism=Escherichia coli, GI1790861, Length=221, Percent_Identity=28.0542986425339, Blast_Score=93, Evalue=6e-20,
Organism=Escherichia coli, GI1790551, Length=238, Percent_Identity=28.9915966386555, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI87081816, Length=240, Percent_Identity=27.9166666666667, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI1787894, Length=223, Percent_Identity=26.457399103139, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1790300, Length=374, Percent_Identity=27.0053475935829, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI87082128, Length=233, Percent_Identity=23.175965665236, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1789808, Length=229, Percent_Identity=29.2576419213974, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1789403, Length=206, Percent_Identity=25.7281553398058, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1788279, Length=212, Percent_Identity=27.8301886792453, Blast_Score=66, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 70331; Mature: 70331

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: PS50885 HAMP ; PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKVSFFRSIHFKFTLIYVLLIIVAMQIIGVYFVNEMEKSLLKSYNDSLDQRVNNLSYYL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQEMTKDRSTSSSSTLKEDAERILNDFSKEGEILEVSLIDKSYEVIATSNPYNREVAGKK
HHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCEEEEECCCCCCCCCCCCH
TTEGIIKRTLLVGIPYENKFFDPERDSKVRISVTPIKKSNQETIGAIYVVASMDNVYNQI
HHHHHHHHHHHEECCCCCCCCCCCCCCEEEEEEECCCCCCCCHHEEEEEEECHHHHHHHH
RTINTILASGTFIALGITAFLGIFVARTITHPLSDMRKQAIELAKGNFSRKVRKYGNDEI
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHH
GQLATTFNYLTRELKEAQSMTEGERKKLSSVIAYMTDGVIATNRNGAIILLNTPALELLN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCEEEEEECCHHHHHH
VSRETALEMPITSLLGLEDEYTFEDLVEQQDSLLLEIEQEERTSVLRVNFSVIQKEHGKI
CCHHHHHHCCHHHHHCCCCCCCHHHHHHHCCCEEEEECCCCCCEEEEEHHHHHHHHCCCC
DGLIAVIYDVTEQEQIDQERREFVANVSHELRTPLTTMRSYLEALAEGAWQDPNIAPRFL
CHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCHHC
NVTQNETERMIRLVNDLLQLSKFDSKDYQFNKEWIHFIRFFSLIIERFEMTKEQHVEFIS
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NLPDRELYVEIDPDKITQVLDNIISNALKYSPEGGHITFSVDVNEEEELLYVSVKDEGVG
CCCCCEEEEEECHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCEEEEEEECCCCC
IPRKDVEKIFERFYRVDKARTRRLGGTGLGLAIAKEMVQAHSGDIWADSIEGKGTTITFT
CCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCEEEEE
LPYKEEQEDDWDEA
ECCCCCCCCCCCCC
>Mature Secondary Structure
MNKVSFFRSIHFKFTLIYVLLIIVAMQIIGVYFVNEMEKSLLKSYNDSLDQRVNNLSYYL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EQEMTKDRSTSSSSTLKEDAERILNDFSKEGEILEVSLIDKSYEVIATSNPYNREVAGKK
HHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCEEEEECCCCCCCCCCCCH
TTEGIIKRTLLVGIPYENKFFDPERDSKVRISVTPIKKSNQETIGAIYVVASMDNVYNQI
HHHHHHHHHHHEECCCCCCCCCCCCCCEEEEEEECCCCCCCCHHEEEEEEECHHHHHHHH
RTINTILASGTFIALGITAFLGIFVARTITHPLSDMRKQAIELAKGNFSRKVRKYGNDEI
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCHH
GQLATTFNYLTRELKEAQSMTEGERKKLSSVIAYMTDGVIATNRNGAIILLNTPALELLN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCEEEEEECCHHHHHH
VSRETALEMPITSLLGLEDEYTFEDLVEQQDSLLLEIEQEERTSVLRVNFSVIQKEHGKI
CCHHHHHHCCHHHHHCCCCCCCHHHHHHHCCCEEEEECCCCCCEEEEEHHHHHHHHCCCC
DGLIAVIYDVTEQEQIDQERREFVANVSHELRTPLTTMRSYLEALAEGAWQDPNIAPRFL
CHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCHHC
NVTQNETERMIRLVNDLLQLSKFDSKDYQFNKEWIHFIRFFSLIIERFEMTKEQHVEFIS
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NLPDRELYVEIDPDKITQVLDNIISNALKYSPEGGHITFSVDVNEEEELLYVSVKDEGVG
CCCCCEEEEEECHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCCEEEEEEECCCCC
IPRKDVEKIFERFYRVDKARTRRLGGTGLGLAIAKEMVQAHSGDIWADSIEGKGTTITFT
CCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEECCCCCCCEEEEE
LPYKEEQEDDWDEA
ECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 9829949; 10878122; 11758928 [H]