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The map label for this gene is dra

Identifier: 52787906

GI number: 52787906

Start: 4064650

End: 4065321

Strand: Reverse

Name: dra

Synonym: BLi04229

Alternate gene names: 52787906

Gene position: 4065321-4064650 (Counterclockwise)

Preceding gene: 52787907

Following gene: 52787905

Centisome position: 96.27

GC content: 50.74

Gene sequence:

>672_bases
ATGACGATTGCAAATCTCATTGATCATACAGCATTGAAACCGCATACACAAAAATCCGAGATTAAGAAATTAATAGAAGA
AGCGAAAGCATACCAATTCGCTTCAGTCTGCGTCAACCCGACATGGGTCGAATTTGCCGCCGAAGAGCTGAAGGGAACGG
AAATCGACGTTTGCACGGTCATCGGTTTTCCGCTGGGCGCCAACACGACAGAGACAAAAGCGTTTGAAACAAAAGACGCT
ATCGCAAAAGGCGCGACAGAGGTGGACATGGTCATCAACATCGCCGCTTTAAAAGACGGAAACGATGACTTTGTCGAGGC
CGACATCCGCGCGGTCGTTGAAGCCGCAAAAGGTAAAGCGCTTGTTAAAGTCATCATTGAAACGTGTCTGTTGACAGACG
AAGAAAAAGAGCGCGCCTGCCGCCTGGCTGTTGCTGCCGGTGCCGACTTTGTCAAAACCTCAACCGGGTTCTCAACCGGC
GGAGCGACAGCGGAAGATATCGCCCTGATGCGGAAAACCGTCGGACCTGACATCGGTGTCAAAGCATCCGGAGGGATTCG
TACAAAAGAGGACGTTGAAACCATGATCTCAAACGGCGCGACCCGGATCGGTGCAAGCGCAGGCGTTTCCATCGTCAGCG
GAGCAGAAGGAAAAAATGAAGATAACTACTAA

Upstream 100 bases:

>100_bases
TTTACTTTATTTTCTATTGAACAAAATTTCATATGATAATTTACATTTGTTCAAAAATCGGTTATGCTGAAACTATCTTA
TACAAAGGAAGTGCTAGTAA

Downstream 100 bases:

>100_bases
GATCCAGTGCGGCGGGAAGCGGAAGCTTCCTGCGCGCAGATACAAAAATGTAAGCGAATACATCACCAGGAGGATCAAAA
CATGAAATATCTCATCGGGC

Product: Dra

Products: NA

Alternate protein names: Phosphodeoxyriboaldolase 2; DERA 2; Deoxyriboaldolase 2

Number of amino acids: Translated: 223; Mature: 222

Protein sequence:

>223_residues
MTIANLIDHTALKPHTQKSEIKKLIEEAKAYQFASVCVNPTWVEFAAEELKGTEIDVCTVIGFPLGANTTETKAFETKDA
IAKGATEVDMVINIAALKDGNDDFVEADIRAVVEAAKGKALVKVIIETCLLTDEEKERACRLAVAAGADFVKTSTGFSTG
GATAEDIALMRKTVGPDIGVKASGGIRTKEDVETMISNGATRIGASAGVSIVSGAEGKNEDNY

Sequences:

>Translated_223_residues
MTIANLIDHTALKPHTQKSEIKKLIEEAKAYQFASVCVNPTWVEFAAEELKGTEIDVCTVIGFPLGANTTETKAFETKDA
IAKGATEVDMVINIAALKDGNDDFVEADIRAVVEAAKGKALVKVIIETCLLTDEEKERACRLAVAAGADFVKTSTGFSTG
GATAEDIALMRKTVGPDIGVKASGGIRTKEDVETMISNGATRIGASAGVSIVSGAEGKNEDNY
>Mature_222_residues
TIANLIDHTALKPHTQKSEIKKLIEEAKAYQFASVCVNPTWVEFAAEELKGTEIDVCTVIGFPLGANTTETKAFETKDAI
AKGATEVDMVINIAALKDGNDDFVEADIRAVVEAAKGKALVKVIIETCLLTDEEKERACRLAVAAGADFVKTSTGFSTGG
ATAEDIALMRKTVGPDIGVKASGGIRTKEDVETMISNGATRIGASAGVSIVSGAEGKNEDNY

Specific function: Nucleotide and deoxyribonucleotide catabolism. [C]

COG id: COG0274

COG function: function code F; Deoxyribose-phosphate aldolase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the deoC/fbaB aldolase family. DeoC type 1 subfamily

Homologues:

Organism=Homo sapiens, GI116063554, Length=188, Percent_Identity=35.6382978723404, Blast_Score=77, Evalue=1e-14,
Organism=Escherichia coli, GI1790841, Length=215, Percent_Identity=36.2790697674419, Blast_Score=89, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17533015, Length=174, Percent_Identity=31.6091954022989, Blast_Score=66, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DEOC2_BACLD (Q65D22)

Other databases:

- EMBL:   AE017333
- EMBL:   CP000002
- RefSeq:   YP_081301.1
- RefSeq:   YP_093735.1
- ProteinModelPortal:   Q65D22
- SMR:   Q65D22
- STRING:   Q65D22
- EnsemblBacteria:   EBBACT00000055542
- EnsemblBacteria:   EBBACT00000060560
- GeneID:   3031406
- GeneID:   3100763
- GenomeReviews:   AE017333_GR
- GenomeReviews:   CP000002_GR
- KEGG:   bld:BLi04229
- KEGG:   bli:BL00229
- NMPDR:   fig|279010.5.peg.3883
- eggNOG:   COG0274
- GeneTree:   EBGT00050000000908
- HOGENOM:   HBG636421
- OMA:   CLEAREN
- ProtClustDB:   CLSK929138
- BioCyc:   BLIC279010-1:BLI04229-MONOMER
- BioCyc:   BLIC279010:BL00229-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00114
- InterPro:   IPR013785
- InterPro:   IPR011343
- InterPro:   IPR002915
- InterPro:   IPR022979
- Gene3D:   G3DSA:3.20.20.70
- PANTHER:   PTHR10889
- PIRSF:   PIRSF001357
- TIGRFAMs:   TIGR00126

Pfam domain/function: PF01791 DeoC

EC number: =4.1.2.4

Molecular weight: Translated: 23456; Mature: 23325

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: NA

Important sites: ACT_SITE 152-152 ACT_SITE 181-181

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIANLIDHTALKPHTQKSEIKKLIEEAKAYQFASVCVNPTWVEFAAEELKGTEIDVCTV
CCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEE
IGFPLGANTTETKAFETKDAIAKGATEVDMVINIAALKDGNDDFVEADIRAVVEAAKGKA
EECCCCCCCCCCHHHHHHHHHHCCCCCCHHEEEEEEECCCCCHHHHHHHHHHHHHHCCHH
LVKVIIETCLLTDEEKERACRLAVAAGADFVKTSTGFSTGGATAEDIALMRKTVGPDIGV
HHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCC
KASGGIRTKEDVETMISNGATRIGASAGVSIVSGAEGKNEDNY
CCCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCCCCC
>Mature Secondary Structure 
TIANLIDHTALKPHTQKSEIKKLIEEAKAYQFASVCVNPTWVEFAAEELKGTEIDVCTV
CHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEE
IGFPLGANTTETKAFETKDAIAKGATEVDMVINIAALKDGNDDFVEADIRAVVEAAKGKA
EECCCCCCCCCCHHHHHHHHHHCCCCCCHHEEEEEEECCCCCHHHHHHHHHHHHHHCCHH
LVKVIIETCLLTDEEKERACRLAVAAGADFVKTSTGFSTGGATAEDIALMRKTVGPDIGV
HHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHCCCCCCCCCCCCHHHHHHHHHHCCCCCCC
KASGGIRTKEDVETMISNGATRIGASAGVSIVSGAEGKNEDNY
CCCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA