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The map label for this gene is katE2 [H]

Identifier: 52787874

GI number: 52787874

Start: 4027263

End: 4027880

Strand: Reverse

Name: katE2 [H]

Synonym: BLi04197

Alternate gene names: 52787874

Gene position: 4027880-4027263 (Counterclockwise)

Preceding gene: 52787875

Following gene: 52787873

Centisome position: 95.39

GC content: 50.49

Gene sequence:

>618_bases
GTGAATAACAATGATGGCCGCCGCAAAGTCAATGGGCACAGCAAGGATCAACAACTCGAACAGTACCGGTCTGACAACAG
GGGCAAAAAAATGACGACGAACCAAGGTTTGCGCGTATCTGAAGACGAGCACTCCTTAAAAGCAGGCGTGCGCGGTCCGA
CGCTGATGGAGGACTTTCATTTCCGTGAAAAAATGACCCATTTTGACCATGAACGGATTCCGGAGCGAGTCGTTCATGCG
AGGGGGTTTGGCGCGCATGGCTATTTTCAGGTTTACGAGCCGATGACGGAGTATACGAAAGCAAAGTTTCTTCAAGATCC
GTCAGTGAAAACACCGGTGTTTGTCAGGTTCTCGACTGTCGCCGGTTCCAGGGGCTCGGGTGACACTGTACGCGATGTCA
GAGGATTTGCGACAAAGTTTTATACAGAAGAAGGGAACTATGATCTTGTCGGCAACAACATCCCCGTTTTCTTCATTCAG
GATGCCATCAAGTTCCCTGACCTGGTGCACGCCTTTAAACCGGAACCGAACAACGAAATGCCGCAGGCTTCTACGGCGCA
CGATACGTTTTGGGACTTTGTCGCCAACAATGAAGAAACGGCCCACATGATCATGTGA

Upstream 100 bases:

>100_bases
GAATCTATAAAAAGAGTTTAACCCGCCGACAGAAAGGGTAAATCATAAAATAGCATTCCAGATCAGCTACATAGGGAATA
AAAATGAGGAGGGATGACAA

Downstream 100 bases:

>100_bases
GCAATGTCTGACAGGGCGATTCCGCGAAGCTACAGGATGATGGAAGGCTTCGGCGTTCATACGTTCAGGTTTGTAAACGA
AGAAGGCAAGGCGCACTTTG

Product: KatE2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 205; Mature: 205

Protein sequence:

>205_residues
MNNNDGRRKVNGHSKDQQLEQYRSDNRGKKMTTNQGLRVSEDEHSLKAGVRGPTLMEDFHFREKMTHFDHERIPERVVHA
RGFGAHGYFQVYEPMTEYTKAKFLQDPSVKTPVFVRFSTVAGSRGSGDTVRDVRGFATKFYTEEGNYDLVGNNIPVFFIQ
DAIKFPDLVHAFKPEPNNEMPQASTAHDTFWDFVANNEETAHMIM

Sequences:

>Translated_205_residues
MNNNDGRRKVNGHSKDQQLEQYRSDNRGKKMTTNQGLRVSEDEHSLKAGVRGPTLMEDFHFREKMTHFDHERIPERVVHA
RGFGAHGYFQVYEPMTEYTKAKFLQDPSVKTPVFVRFSTVAGSRGSGDTVRDVRGFATKFYTEEGNYDLVGNNIPVFFIQ
DAIKFPDLVHAFKPEPNNEMPQASTAHDTFWDFVANNEETAHMIM
>Mature_205_residues
MNNNDGRRKVNGHSKDQQLEQYRSDNRGKKMTTNQGLRVSEDEHSLKAGVRGPTLMEDFHFREKMTHFDHERIPERVVHA
RGFGAHGYFQVYEPMTEYTKAKFLQDPSVKTPVFVRFSTVAGSRGSGDTVRDVRGFATKFYTEEGNYDLVGNNIPVFFIQ
DAIKFPDLVHAFKPEPNNEMPQASTAHDTFWDFVANNEETAHMIM

Specific function: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide. Involved in sporulation [H]

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family. HPII subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557014, Length=188, Percent_Identity=48.4042553191489, Blast_Score=184, Evalue=5e-47,
Organism=Escherichia coli, GI48994891, Length=191, Percent_Identity=64.9214659685864, Blast_Score=268, Evalue=2e-73,
Organism=Caenorhabditis elegans, GI25151141, Length=195, Percent_Identity=50.2564102564103, Blast_Score=192, Evalue=7e-50,
Organism=Caenorhabditis elegans, GI25147792, Length=191, Percent_Identity=50.261780104712, Blast_Score=191, Evalue=3e-49,
Organism=Caenorhabditis elegans, GI71998444, Length=191, Percent_Identity=46.5968586387435, Blast_Score=178, Evalue=2e-45,
Organism=Saccharomyces cerevisiae, GI6320462, Length=185, Percent_Identity=43.2432432432432, Blast_Score=149, Evalue=3e-37,
Organism=Saccharomyces cerevisiae, GI6321525, Length=153, Percent_Identity=46.4052287581699, Blast_Score=146, Evalue=2e-36,
Organism=Drosophila melanogaster, GI17981717, Length=175, Percent_Identity=49.7142857142857, Blast_Score=179, Evalue=1e-45,
Organism=Drosophila melanogaster, GI19920968, Length=190, Percent_Identity=40.5263157894737, Blast_Score=156, Evalue=7e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002226
- InterPro:   IPR020835
- InterPro:   IPR010582
- InterPro:   IPR018028
- InterPro:   IPR011614
- InterPro:   IPR002818 [H]

Pfam domain/function: PF00199 Catalase; PF06628 Catalase-rel; PF01965 DJ-1_PfpI [H]

EC number: =1.11.1.6 [H]

Molecular weight: Translated: 23564; Mature: 23564

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: PS00438 CATALASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNNDGRRKVNGHSKDQQLEQYRSDNRGKKMTTNQGLRVSEDEHSLKAGVRGPTLMEDFH
CCCCCCCEECCCCCHHHHHHHHHCCCCCCEEECCCCCEECCCHHHHHCCCCCCHHHHHHH
FREKMTHFDHERIPERVVHARGFGAHGYFQVYEPMTEYTKAKFLQDPSVKTPVFVRFSTV
HHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEE
AGSRGSGDTVRDVRGFATKFYTEEGNYDLVGNNIPVFFIQDAIKFPDLVHAFKPEPNNEM
CCCCCCCCHHHHHHHHHHHHEECCCCEEEECCCCCEEEECCHHCCHHHHHHCCCCCCCCC
PQASTAHDTFWDFVANNEETAHMIM
CCCCCCHHHHHHHHCCCCCCEEECC
>Mature Secondary Structure
MNNNDGRRKVNGHSKDQQLEQYRSDNRGKKMTTNQGLRVSEDEHSLKAGVRGPTLMEDFH
CCCCCCCEECCCCCHHHHHHHHHCCCCCCEEECCCCCEECCCHHHHHCCCCCCHHHHHHH
FREKMTHFDHERIPERVVHARGFGAHGYFQVYEPMTEYTKAKFLQDPSVKTPVFVRFSTV
HHHHHHHCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEE
AGSRGSGDTVRDVRGFATKFYTEEGNYDLVGNNIPVFFIQDAIKFPDLVHAFKPEPNNEM
CCCCCCCCHHHHHHHHHHHHEECCCCEEEECCCCCEEEECCHHCCHHHHHHCCCCCCCCC
PQASTAHDTFWDFVANNEETAHMIM
CCCCCCHHHHHHHHCCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969509; 9384377 [H]