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The map label for this gene is katE1 [H]

Identifier: 52787873

GI number: 52787873

Start: 4025799

End: 4027259

Strand: Reverse

Name: katE1 [H]

Synonym: BLi04196

Alternate gene names: 52787873

Gene position: 4027259-4025799 (Counterclockwise)

Preceding gene: 52787874

Following gene: 52787871

Centisome position: 95.37

GC content: 51.75

Gene sequence:

>1461_bases
ATGTCTGACAGGGCGATTCCGCGAAGCTACAGGATGATGGAAGGCTTCGGCGTTCATACGTTCAGGTTTGTAAACGAAGA
AGGCAAGGCGCACTTTGTTAAATTTCACTGGAAGCCCGTCCTCGGCGTCCATTCGCTCGTCTGGGACGAAGCGCAGACAA
TCGCCGGAAAAGATCCCGACTATCACCGCCGCGATCTGTGGGAAGCGATCGAAAGAGGCGATGAAGTGGAGTATGAGCTC
GGCGTGCAAATGATTGACGAAGAAGACGAGTTCAAGTTTGACTTCGATATCCTTGACCCGACAAAGCTTTGGCCGGAAGA
AATCGTCCCTGTCAAAATCATCGGCAAAATGACGCTGAATCGAAACCAGGATAACGTTTTTGCGGAAACCGAACAGGCCG
CTTTCCATCCGGGCCATGTTGTGCCGGGGATCGATTTCACAAACGATCCGCTATTGCAAGGCCGGCTCTTTTCTTATACG
GACACACAGCTGATCCGATTGGGAGGTCCGAACTTTCACGAAATTCCAATCAACCGCCCGGTCTGTCCGTTCCATAACAA
CCAGTATGACGGCTATCACAGGATGACGATTAACAAAGGGCCTGTCGCTTATCATAAAAATTCGCTTCAAAACAACGATC
CGGCGCCTGCTTCAGAAGAAGAAGGCGGATATGTGCACTACGAGGAAAAAGTCGAGGGCAAAAAAATCCGCCAGCGCAGC
GAAAGCTTTAACGACCACTATTCGCAAGCGAAGCTGTTTTGGAACAGCATGTCCCCCGTTGAAAAAGAACATATCATTTC
GGCGTTCCGCTTTGAAGTCGGAAAGGTCAAAAGCAAGGACGTCCGCCGCCAAGTCGTTCATATGTTTAACCGGGTTGACG
GGGAGCTTGCCAAGCAAATCGCTGCGGGTGTAGGCGTAGAGCCCCCTGAAAAAGACGAAGGCTCCAACGTGACGTTCAAA
TCCCCTGCGCTCAGCCAGGAGAATACGGTGAAACTGCCGCAGACAAGGACAGTCGCCATTTTAGCAGAACAAGGTTTTGA
TGATGAAGACTTGAGCCGTGTGTTGAAAGAATTCAAAAAAGCCGGCATCATTCCGGACATCGTCAGCTCGGCACTCGGAG
TAATCGAAGGGGCCGGCGGCACAGAAATTGAAGTCGGAAACACTTTGCAGACGGTCGATTCTGTGCTGTACGATGCCGTT
TATATTCCGGGCGGCCAAGAAAGCATAGAACGCCTGAAATTGCATAAAGCCGCATCGGATTTTGTCAATGAAGCATTCGG
ACATTATAAAGCGGTCGGAGCCGCAGGCGAAGGGGTCGATCTCCTGCTGTCCGCCGCCGGGGCCCACGCGGCTTCACAGC
CGGGCATTATCACCTCTCGTGGTGATAAGAACAAAGACGACTTCGGCAAAAAGCTGGTCGAAGCGATCAGCGGGCACCGC
CATTGGGATAGGCAAGTTTAA

Upstream 100 bases:

>100_bases
GGAACCGAACAACGAAATGCCGCAGGCTTCTACGGCGCACGATACGTTTTGGGACTTTGTCGCCAACAATGAAGAAACGG
CCCACATGATCATGTGAGCA

Downstream 100 bases:

>100_bases
TAATAAAGCAGGCAGGCTAGATGCCTGCCCTTTTAATCTATTTTTCTACCAAACAAACAGCCCGACAATCCCCGCGCTCA
ACAGCGACACTGCTATTCCG

Product: KatE1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 486; Mature: 485

Protein sequence:

>486_residues
MSDRAIPRSYRMMEGFGVHTFRFVNEEGKAHFVKFHWKPVLGVHSLVWDEAQTIAGKDPDYHRRDLWEAIERGDEVEYEL
GVQMIDEEDEFKFDFDILDPTKLWPEEIVPVKIIGKMTLNRNQDNVFAETEQAAFHPGHVVPGIDFTNDPLLQGRLFSYT
DTQLIRLGGPNFHEIPINRPVCPFHNNQYDGYHRMTINKGPVAYHKNSLQNNDPAPASEEEGGYVHYEEKVEGKKIRQRS
ESFNDHYSQAKLFWNSMSPVEKEHIISAFRFEVGKVKSKDVRRQVVHMFNRVDGELAKQIAAGVGVEPPEKDEGSNVTFK
SPALSQENTVKLPQTRTVAILAEQGFDDEDLSRVLKEFKKAGIIPDIVSSALGVIEGAGGTEIEVGNTLQTVDSVLYDAV
YIPGGQESIERLKLHKAASDFVNEAFGHYKAVGAAGEGVDLLLSAAGAHAASQPGIITSRGDKNKDDFGKKLVEAISGHR
HWDRQV

Sequences:

>Translated_486_residues
MSDRAIPRSYRMMEGFGVHTFRFVNEEGKAHFVKFHWKPVLGVHSLVWDEAQTIAGKDPDYHRRDLWEAIERGDEVEYEL
GVQMIDEEDEFKFDFDILDPTKLWPEEIVPVKIIGKMTLNRNQDNVFAETEQAAFHPGHVVPGIDFTNDPLLQGRLFSYT
DTQLIRLGGPNFHEIPINRPVCPFHNNQYDGYHRMTINKGPVAYHKNSLQNNDPAPASEEEGGYVHYEEKVEGKKIRQRS
ESFNDHYSQAKLFWNSMSPVEKEHIISAFRFEVGKVKSKDVRRQVVHMFNRVDGELAKQIAAGVGVEPPEKDEGSNVTFK
SPALSQENTVKLPQTRTVAILAEQGFDDEDLSRVLKEFKKAGIIPDIVSSALGVIEGAGGTEIEVGNTLQTVDSVLYDAV
YIPGGQESIERLKLHKAASDFVNEAFGHYKAVGAAGEGVDLLLSAAGAHAASQPGIITSRGDKNKDDFGKKLVEAISGHR
HWDRQV
>Mature_485_residues
SDRAIPRSYRMMEGFGVHTFRFVNEEGKAHFVKFHWKPVLGVHSLVWDEAQTIAGKDPDYHRRDLWEAIERGDEVEYELG
VQMIDEEDEFKFDFDILDPTKLWPEEIVPVKIIGKMTLNRNQDNVFAETEQAAFHPGHVVPGIDFTNDPLLQGRLFSYTD
TQLIRLGGPNFHEIPINRPVCPFHNNQYDGYHRMTINKGPVAYHKNSLQNNDPAPASEEEGGYVHYEEKVEGKKIRQRSE
SFNDHYSQAKLFWNSMSPVEKEHIISAFRFEVGKVKSKDVRRQVVHMFNRVDGELAKQIAAGVGVEPPEKDEGSNVTFKS
PALSQENTVKLPQTRTVAILAEQGFDDEDLSRVLKEFKKAGIIPDIVSSALGVIEGAGGTEIEVGNTLQTVDSVLYDAVY
IPGGQESIERLKLHKAASDFVNEAFGHYKAVGAAGEGVDLLLSAAGAHAASQPGIITSRGDKNKDDFGKKLVEAISGHRH
WDRQV

Specific function: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide. Involved in sporulation [H]

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family. HPII subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557014, Length=327, Percent_Identity=33.6391437308869, Blast_Score=167, Evalue=2e-41,
Organism=Escherichia coli, GI48994891, Length=498, Percent_Identity=49.1967871485944, Blast_Score=476, Evalue=1e-135,
Organism=Caenorhabditis elegans, GI71998444, Length=308, Percent_Identity=37.3376623376623, Blast_Score=197, Evalue=1e-50,
Organism=Caenorhabditis elegans, GI25147792, Length=309, Percent_Identity=36.2459546925566, Blast_Score=185, Evalue=5e-47,
Organism=Caenorhabditis elegans, GI25151141, Length=309, Percent_Identity=36.2459546925566, Blast_Score=185, Evalue=5e-47,
Organism=Saccharomyces cerevisiae, GI6320462, Length=184, Percent_Identity=44.0217391304348, Blast_Score=169, Evalue=9e-43,
Organism=Saccharomyces cerevisiae, GI6321525, Length=351, Percent_Identity=30.7692307692308, Blast_Score=153, Evalue=7e-38,
Organism=Drosophila melanogaster, GI19920968, Length=260, Percent_Identity=36.5384615384615, Blast_Score=169, Evalue=3e-42,
Organism=Drosophila melanogaster, GI17981717, Length=307, Percent_Identity=32.8990228013029, Blast_Score=167, Evalue=1e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002226
- InterPro:   IPR020835
- InterPro:   IPR010582
- InterPro:   IPR018028
- InterPro:   IPR011614
- InterPro:   IPR002818 [H]

Pfam domain/function: PF00199 Catalase; PF06628 Catalase-rel; PF01965 DJ-1_PfpI [H]

EC number: =1.11.1.6 [H]

Molecular weight: Translated: 54518; Mature: 54386

Theoretical pI: Translated: 5.57; Mature: 5.57

Prosite motif: PS00437 CATALASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDRAIPRSYRMMEGFGVHTFRFVNEEGKAHFVKFHWKPVLGVHSLVWDEAQTIAGKDPD
CCCCCCCHHHHHHHCCCCEEEEEECCCCCEEEEEEECCHHHHHHHHHHHHHHHHCCCCCC
YHRRDLWEAIERGDEVEYELGVQMIDEEDEFKFDFDILDPTKLWPEEIVPVKIIGKMTLN
HHHHHHHHHHHCCCCEEEEECCEEECCCCCEEEEEEECCCCCCCHHHCCCEEEEEEEEEC
RNQDNVFAETEQAAFHPGHVVPGIDFTNDPLLQGRLFSYTDTQLIRLGGPNFHEIPINRP
CCCCCEEECCHHHCCCCCCCCCCCCCCCCCCCCCEEECCCCCEEEEECCCCCEECCCCCC
VCPFHNNQYDGYHRMTINKGPVAYHKNSLQNNDPAPASEEEGGYVHYEEKVEGKKIRQRS
CCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHCCHHHHHHHH
ESFNDHYSQAKLFWNSMSPVEKEHIISAFRFEVGKVKSKDVRRQVVHMFNRVDGELAKQI
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHH
AAGVGVEPPEKDEGSNVTFKSPALSQENTVKLPQTRTVAILAEQGFDDEDLSRVLKEFKK
HHCCCCCCCCCCCCCCEEECCCCCCCCCCEECCCCCEEEEEECCCCCHHHHHHHHHHHHH
AGIIPDIVSSALGVIEGAGGTEIEVGNTLQTVDSVLYDAVYIPGGQESIERLKLHKAASD
CCCCHHHHHHHHHHEECCCCCEEEECCHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHH
FVNEAFGHYKAVGAAGEGVDLLLSAAGAHAASQPGIITSRGDKNKDDFGKKLVEAISGHR
HHHHHHHHHHECCCCCCCHHHHHHHHCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHCCC
HWDRQV
CCCCCC
>Mature Secondary Structure 
SDRAIPRSYRMMEGFGVHTFRFVNEEGKAHFVKFHWKPVLGVHSLVWDEAQTIAGKDPD
CCCCCCHHHHHHHCCCCEEEEEECCCCCEEEEEEECCHHHHHHHHHHHHHHHHCCCCCC
YHRRDLWEAIERGDEVEYELGVQMIDEEDEFKFDFDILDPTKLWPEEIVPVKIIGKMTLN
HHHHHHHHHHHCCCCEEEEECCEEECCCCCEEEEEEECCCCCCCHHHCCCEEEEEEEEEC
RNQDNVFAETEQAAFHPGHVVPGIDFTNDPLLQGRLFSYTDTQLIRLGGPNFHEIPINRP
CCCCCEEECCHHHCCCCCCCCCCCCCCCCCCCCCEEECCCCCEEEEECCCCCEECCCCCC
VCPFHNNQYDGYHRMTINKGPVAYHKNSLQNNDPAPASEEEGGYVHYEEKVEGKKIRQRS
CCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHCCHHHHHHHH
ESFNDHYSQAKLFWNSMSPVEKEHIISAFRFEVGKVKSKDVRRQVVHMFNRVDGELAKQI
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHH
AAGVGVEPPEKDEGSNVTFKSPALSQENTVKLPQTRTVAILAEQGFDDEDLSRVLKEFKK
HHCCCCCCCCCCCCCCEEECCCCCCCCCCEECCCCCEEEEEECCCCCHHHHHHHHHHHHH
AGIIPDIVSSALGVIEGAGGTEIEVGNTLQTVDSVLYDAVYIPGGQESIERLKLHKAASD
CCCCHHHHHHHHHHEECCCCCEEEECCHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHH
FVNEAFGHYKAVGAAGEGVDLLLSAAGAHAASQPGIITSRGDKNKDDFGKKLVEAISGHR
HHHHHHHHHHECCCCCCCHHHHHHHHCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHCCC
HWDRQV
CCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969509; 9384377 [H]