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The map label for this gene is asnC [H]

Identifier: 52786115

GI number: 52786115

Start: 2316797

End: 2318089

Strand: Reverse

Name: asnC [H]

Synonym: BLi02371

Alternate gene names: 52786115

Gene position: 2318089-2316797 (Counterclockwise)

Preceding gene: 52786116

Following gene: 52786114

Centisome position: 54.9

GC content: 46.4

Gene sequence:

>1293_bases
GTGAAAACAACAATAAACCAAGTGTACAAGCATGTTGGTGAAGAAGTAACAATCGGCGCTTGGATCGCCAACAAACGTTC
AAGCGGCAAAATTGCGTTTTTGCAGCTTAGAGACGGGACAGGCTTTATCCAAGGAGTCGTCGTCAAAGCGGAAGTGGACG
AAGAAACATTTCAAACCGCTAAGTCTGTAACACAGGAAACATCATTATATGTAAAAGGCGTCGTCAAAGAAGACGAGCGT
TCGCCTCTCGGCTACGAGCTTGCTGTGACGTCGCTTGAAGTCATCCATGAAGCGACAGATTATCCGATTACACCTAAAGA
ACACGGAACAGAATTTTTGATGGATCACAGACATTTGTGGCTCCGTTCAAAACGGCAGCATGCAACGATGAAAATCCGCA
ACGAGATTATTCGCGCTACATACGAATTTTTCAATAAGGAAGGCTTTGTTAAAGTCGATCCTCCGATTTTGACGGGAAGC
GCACCCGAAGGAACGACAGAGCTTTTTGCGACAAAGTATTTTGACGAAGATGCCTACCTTTCGCAAAGCGGCCAGCTTTA
CATGGAAGCTGCTGCAATGGCTTTAGGAAAAGTCTTTTCATTCGGACCGACTTTCAGAGCTGAGAAATCAAAAACGAAGC
GCCATCTGATCGAATTCTGGATGATCGAGCCGGAAATGGCTTTTGTCGAATTCAACGAAAACCTTGAAGTTCAAGAGAAC
TATGTCTCTTTTATCGTCCAAAGCGTGCTTGAAAACTGCAAAATAGAACTGAATACGCTCGGCAGAGACACTTCCAAGCT
GGAGCTTATCAAAGCGCCTTTCCCAAGAATCACGTATGATGAAGCAATTCAGTTCTTAAAAGAGAAAGGCTTTGACGATA
TTGAATGGGGCGATGACTTCGGCGCTCCTCACGAAACGGCGATTGCTGAAAGCTATGACAAGCCGGTATTTATTACACAC
TATCCGACATCATTAAAGCCGTTTTATATGCAGCCTGCACCTGACAGGGAAGATGTCGTATTGTGCGCTGACTTGATTGC
GCCTGAAGGCTACGGCGAGATTATCGGCGGATCTGAACGGATTCATGATCTCGAGCTTCTCGAAGCGCGCCTGAAAGAGC
ACGGTTTAGAATCGGACGCTTATCAATGGTATGCAGAGCTGAGAAAATACGGCTCAGTTCCGCATTCAGGGTTCGGACTC
GGACTTGAACGGACGGTTGCCTGGATCTGCGGCTCTCCGCACGTCCGCGAAACGATTCCGTTCCCAAGACTGTTAAATCG
CTTATATCCTTAA

Upstream 100 bases:

>100_bases
CATTGACCTGATCGATTTAAAAAAGGTATAATATACGTTATGGACGTCAGAAAGAATGATGGCTTGACCGAATTCTTTCG
TGTTTTGGAGGGAAACGATA

Downstream 100 bases:

>100_bases
GAAAAAAGTCTCCTGATTGCAGGAGACTTTTTCACAGTCATCCATGATATACTGGAAGGTAAGAGGTGTATCGAATGAAA
AAACAGCACTTTATTAAGAT

Product: asparaginyl-tRNA synthetase

Products: NA

Alternate protein names: Asparagine--tRNA ligase; AsnRS [H]

Number of amino acids: Translated: 430; Mature: 430

Protein sequence:

>430_residues
MKTTINQVYKHVGEEVTIGAWIANKRSSGKIAFLQLRDGTGFIQGVVVKAEVDEETFQTAKSVTQETSLYVKGVVKEDER
SPLGYELAVTSLEVIHEATDYPITPKEHGTEFLMDHRHLWLRSKRQHATMKIRNEIIRATYEFFNKEGFVKVDPPILTGS
APEGTTELFATKYFDEDAYLSQSGQLYMEAAAMALGKVFSFGPTFRAEKSKTKRHLIEFWMIEPEMAFVEFNENLEVQEN
YVSFIVQSVLENCKIELNTLGRDTSKLELIKAPFPRITYDEAIQFLKEKGFDDIEWGDDFGAPHETAIAESYDKPVFITH
YPTSLKPFYMQPAPDREDVVLCADLIAPEGYGEIIGGSERIHDLELLEARLKEHGLESDAYQWYAELRKYGSVPHSGFGL
GLERTVAWICGSPHVRETIPFPRLLNRLYP

Sequences:

>Translated_430_residues
MKTTINQVYKHVGEEVTIGAWIANKRSSGKIAFLQLRDGTGFIQGVVVKAEVDEETFQTAKSVTQETSLYVKGVVKEDER
SPLGYELAVTSLEVIHEATDYPITPKEHGTEFLMDHRHLWLRSKRQHATMKIRNEIIRATYEFFNKEGFVKVDPPILTGS
APEGTTELFATKYFDEDAYLSQSGQLYMEAAAMALGKVFSFGPTFRAEKSKTKRHLIEFWMIEPEMAFVEFNENLEVQEN
YVSFIVQSVLENCKIELNTLGRDTSKLELIKAPFPRITYDEAIQFLKEKGFDDIEWGDDFGAPHETAIAESYDKPVFITH
YPTSLKPFYMQPAPDREDVVLCADLIAPEGYGEIIGGSERIHDLELLEARLKEHGLESDAYQWYAELRKYGSVPHSGFGL
GLERTVAWICGSPHVRETIPFPRLLNRLYP
>Mature_430_residues
MKTTINQVYKHVGEEVTIGAWIANKRSSGKIAFLQLRDGTGFIQGVVVKAEVDEETFQTAKSVTQETSLYVKGVVKEDER
SPLGYELAVTSLEVIHEATDYPITPKEHGTEFLMDHRHLWLRSKRQHATMKIRNEIIRATYEFFNKEGFVKVDPPILTGS
APEGTTELFATKYFDEDAYLSQSGQLYMEAAAMALGKVFSFGPTFRAEKSKTKRHLIEFWMIEPEMAFVEFNENLEVQEN
YVSFIVQSVLENCKIELNTLGRDTSKLELIKAPFPRITYDEAIQFLKEKGFDDIEWGDDFGAPHETAIAESYDKPVFITH
YPTSLKPFYMQPAPDREDVVLCADLIAPEGYGEIIGGSERIHDLELLEARLKEHGLESDAYQWYAELRKYGSVPHSGFGL
GLERTVAWICGSPHVRETIPFPRLLNRLYP

Specific function: Unknown

COG id: COG0017

COG function: function code J; Aspartyl/asparaginyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI4758762, Length=437, Percent_Identity=33.6384439359268, Blast_Score=247, Evalue=2e-65,
Organism=Homo sapiens, GI226491502, Length=443, Percent_Identity=35.665914221219, Blast_Score=246, Evalue=4e-65,
Organism=Homo sapiens, GI45439306, Length=452, Percent_Identity=30.7522123893805, Blast_Score=180, Evalue=2e-45,
Organism=Homo sapiens, GI40789249, Length=233, Percent_Identity=27.8969957081545, Blast_Score=77, Evalue=3e-14,
Organism=Escherichia coli, GI1787161, Length=450, Percent_Identity=36.2222222222222, Blast_Score=271, Evalue=4e-74,
Organism=Escherichia coli, GI1790571, Length=459, Percent_Identity=24.400871459695, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI1789256, Length=457, Percent_Identity=24.2888402625821, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI1788173, Length=243, Percent_Identity=25.5144032921811, Blast_Score=85, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI71984122, Length=444, Percent_Identity=34.9099099099099, Blast_Score=262, Evalue=3e-70,
Organism=Caenorhabditis elegans, GI17556372, Length=409, Percent_Identity=32.2738386308068, Blast_Score=171, Evalue=5e-43,
Organism=Caenorhabditis elegans, GI17551876, Length=456, Percent_Identity=28.2894736842105, Blast_Score=162, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI32566633, Length=286, Percent_Identity=26.5734265734266, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71994340, Length=471, Percent_Identity=22.2929936305732, Blast_Score=66, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17535927, Length=471, Percent_Identity=22.2929936305732, Blast_Score=65, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17535925, Length=471, Percent_Identity=22.2929936305732, Blast_Score=65, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6321807, Length=443, Percent_Identity=36.117381489842, Blast_Score=279, Evalue=7e-76,
Organism=Saccharomyces cerevisiae, GI6319872, Length=467, Percent_Identity=32.1199143468951, Blast_Score=227, Evalue=3e-60,
Organism=Saccharomyces cerevisiae, GI6323011, Length=461, Percent_Identity=30.1518438177874, Blast_Score=160, Evalue=4e-40,
Organism=Drosophila melanogaster, GI19921528, Length=433, Percent_Identity=34.8729792147806, Blast_Score=246, Evalue=3e-65,
Organism=Drosophila melanogaster, GI19922416, Length=443, Percent_Identity=31.8284424379233, Blast_Score=213, Evalue=2e-55,
Organism=Drosophila melanogaster, GI17136276, Length=461, Percent_Identity=27.114967462039, Blast_Score=167, Evalue=2e-41,
Organism=Drosophila melanogaster, GI24640851, Length=459, Percent_Identity=22.4400871459695, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24640849, Length=468, Percent_Identity=22.6495726495727, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: 80 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR004522
- InterPro:   IPR002312
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365 [H]

Pfam domain/function: PF00152 tRNA-synt_2; PF01336 tRNA_anti [H]

EC number: =6.1.1.22 [H]

Molecular weight: Translated: 48984; Mature: 48984

Theoretical pI: Translated: 4.96; Mature: 4.96

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTTINQVYKHVGEEVTIGAWIANKRSSGKIAFLQLRDGTGFIQGVVVKAEVDEETFQTA
CCCHHHHHHHHCCCCEEEEEEEECCCCCCCEEEEEEECCCCEEEEEEEEEECCHHHHHHH
KSVTQETSLYVKGVVKEDERSPLGYELAVTSLEVIHEATDYPITPKEHGTEFLMDHRHLW
HHHHHHHHEEEEEEECCCCCCCCCEEHHHHHHHHHHHCCCCCCCCHHCCHHHHHHHHHHH
LRSKRQHATMKIRNEIIRATYEFFNKEGFVKVDPPILTGSAPEGTTELFATKYFDEDAYL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCEEECCCCCCCHHHHHHHHCCCCHHH
SQSGQLYMEAAAMALGKVFSFGPTFRAEKSKTKRHLIEFWMIEPEMAFVEFNENLEVQEN
CCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHEEECCCEEEEEECCCCCHHHH
YVSFIVQSVLENCKIELNTLGRDTSKLELIKAPFPRITYDEAIQFLKEKGFDDIEWGDDF
HHHHHHHHHHHHCEEEEEECCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCC
GAPHETAIAESYDKPVFITHYPTSLKPFYMQPAPDREDVVLCADLIAPEGYGEIIGGSER
CCCCHHHHHHCCCCCEEEEECCCCCCCEEECCCCCCCCEEEEEHHHCCCCCCCCCCCCHH
IHDLELLEARLKEHGLESDAYQWYAELRKYGSVPHSGFGLGLERTVAWICGSPHVRETIP
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCHHCCC
FPRLLNRLYP
HHHHHHHHCC
>Mature Secondary Structure
MKTTINQVYKHVGEEVTIGAWIANKRSSGKIAFLQLRDGTGFIQGVVVKAEVDEETFQTA
CCCHHHHHHHHCCCCEEEEEEEECCCCCCCEEEEEEECCCCEEEEEEEEEECCHHHHHHH
KSVTQETSLYVKGVVKEDERSPLGYELAVTSLEVIHEATDYPITPKEHGTEFLMDHRHLW
HHHHHHHHEEEEEEECCCCCCCCCEEHHHHHHHHHHHCCCCCCCCHHCCHHHHHHHHHHH
LRSKRQHATMKIRNEIIRATYEFFNKEGFVKVDPPILTGSAPEGTTELFATKYFDEDAYL
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCEEECCCCCCCHHHHHHHHCCCCHHH
SQSGQLYMEAAAMALGKVFSFGPTFRAEKSKTKRHLIEFWMIEPEMAFVEFNENLEVQEN
CCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHEEECCCEEEEEECCCCCHHHH
YVSFIVQSVLENCKIELNTLGRDTSKLELIKAPFPRITYDEAIQFLKEKGFDDIEWGDDF
HHHHHHHHHHHHCEEEEEECCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCCCCCCCC
GAPHETAIAESYDKPVFITHYPTSLKPFYMQPAPDREDVVLCADLIAPEGYGEIIGGSER
CCCCHHHHHHCCCCCEEEEECCCCCCCEEECCCCCCCCEEEEEHHHCCCCCCCCCCCCHH
IHDLELLEARLKEHGLESDAYQWYAELRKYGSVPHSGFGLGLERTVAWICGSPHVRETIP
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCHHCCC
FPRLLNRLYP
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA