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The map label for this gene is aspB [H]

Identifier: 52786116

GI number: 52786116

Start: 2318239

End: 2319423

Strand: Reverse

Name: aspB [H]

Synonym: BLi02372

Alternate gene names: 52786116

Gene position: 2319423-2318239 (Counterclockwise)

Preceding gene: 52786117

Following gene: 52786115

Centisome position: 54.93

GC content: 48.78

Gene sequence:

>1185_bases
TTGAATCTAGCTAAAAGAGTATCAGCGTTAACACCATCTGCAACATTGGCAATCACTGCAAAAGCAAAAGAATTAAAAGC
GGCAGGGCACGACGTCATCGGTCTTGGGGCAGGTGAGCCGGATTTTAATACGCCTGAGCACATCATTGAAGCGGCTGTCC
GTTCGATGAACGAAGGACATACCAAATACACGCCTTCCGGCGGTCTTGCGGCGCTGAAAGACAGCATCCGCGATAAATTC
AAGCGCGATCAGGGAATTGAATACAGCCAATCGGAAGTTATTGTGTGCACAGGTGCAAAGCATGCTCTTTACACCCTATT
TCAAGTGCTCCTCGACGAAGGGGACGAAGTGATTATTCCGACTCCGTACTGGGTCAGCTATCCTGAACAAGTCAAGCTTG
CAGGCGGCAAACCTGTGTTTGTGGAAGGCCTTGAGGAAAACAGCTTCAAGATTTCTCCGGAGCAGCTCGAAAAAGCCGTC
ACAGAAAAAACGAAGGCTGTGATCATCAATTCCCCAAGCAATCCGACAGGGATGATGTATACGGAAGAAGAGCTCAAAGC
TCTCGGTGAAGTATGCCTTCGACGCAACGTTTTAATCGTATCTGATGAAATATATGAAAAGCTGATTTACGGCGGAAAAA
AACATGTATCCATTGCACAGCTTTCTCCAGAACTTAAAAACCAAACCGTGATCATCAACGGGGTTTCCAAGTCACACAGC
ATGACCGGCTGGAGAATCGGTTATGCAGCAGGCAGCGAACCGATCATTAAAGCGATGACGAACCTAGCCAGCCACAGCAC
GTCAAATCCGACATCTGTCGCTCAATATGGAGCCATTGCCGCTTACAATGGGCCAAACGAGCCTGTTGAGGAGATGAGAA
AAGCTTTTGAAGAACGGCTGAACAAGGTGTATGAACTGCTTGTTGACATTCCGGGATTAACATGCCTGAAGCCTGAAGGA
GCCTTCTACTTGTTCCCGAATGCAAAAAAAGCGGCAGAATCGTGCGGCTTTTCAAGCGTTGATGAATTCGCCGAAGCGCT
TTTGGAAGAAGAAAAGGTTGCGATCGTTCCTGGTTCAGGGTTCGGCGCACCGGACAACATCCGTCTGTCGTATGCGACAT
CCCTGTCACTTTTGGAAGAAGCGGTTGAACGCATCCGCCGCTTTGTCGTGAATCGCAGCCGCTAG

Upstream 100 bases:

>100_bases
CTTAAATAAAGATGGGCAGTACAGTTTAAGCTATGTGGACTTTATAAACGGAAAAATTCACAAAAATATTACGCCTTAGA
CGAAACAGGGGGAAATCGAG

Downstream 100 bases:

>100_bases
AAATTAAAAAGCGTCCGCAGGCGGACGCTTTTTTCATGCACACAACCTGCATTGACCTGATCGATTTAAAAAAGGTATAA
TATACGTTATGGACGTCAGA

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MNLAKRVSALTPSATLAITAKAKELKAAGHDVIGLGAGEPDFNTPEHIIEAAVRSMNEGHTKYTPSGGLAALKDSIRDKF
KRDQGIEYSQSEVIVCTGAKHALYTLFQVLLDEGDEVIIPTPYWVSYPEQVKLAGGKPVFVEGLEENSFKISPEQLEKAV
TEKTKAVIINSPSNPTGMMYTEEELKALGEVCLRRNVLIVSDEIYEKLIYGGKKHVSIAQLSPELKNQTVIINGVSKSHS
MTGWRIGYAAGSEPIIKAMTNLASHSTSNPTSVAQYGAIAAYNGPNEPVEEMRKAFEERLNKVYELLVDIPGLTCLKPEG
AFYLFPNAKKAAESCGFSSVDEFAEALLEEEKVAIVPGSGFGAPDNIRLSYATSLSLLEEAVERIRRFVVNRSR

Sequences:

>Translated_394_residues
MNLAKRVSALTPSATLAITAKAKELKAAGHDVIGLGAGEPDFNTPEHIIEAAVRSMNEGHTKYTPSGGLAALKDSIRDKF
KRDQGIEYSQSEVIVCTGAKHALYTLFQVLLDEGDEVIIPTPYWVSYPEQVKLAGGKPVFVEGLEENSFKISPEQLEKAV
TEKTKAVIINSPSNPTGMMYTEEELKALGEVCLRRNVLIVSDEIYEKLIYGGKKHVSIAQLSPELKNQTVIINGVSKSHS
MTGWRIGYAAGSEPIIKAMTNLASHSTSNPTSVAQYGAIAAYNGPNEPVEEMRKAFEERLNKVYELLVDIPGLTCLKPEG
AFYLFPNAKKAAESCGFSSVDEFAEALLEEEKVAIVPGSGFGAPDNIRLSYATSLSLLEEAVERIRRFVVNRSR
>Mature_394_residues
MNLAKRVSALTPSATLAITAKAKELKAAGHDVIGLGAGEPDFNTPEHIIEAAVRSMNEGHTKYTPSGGLAALKDSIRDKF
KRDQGIEYSQSEVIVCTGAKHALYTLFQVLLDEGDEVIIPTPYWVSYPEQVKLAGGKPVFVEGLEENSFKISPEQLEKAV
TEKTKAVIINSPSNPTGMMYTEEELKALGEVCLRRNVLIVSDEIYEKLIYGGKKHVSIAQLSPELKNQTVIINGVSKSHS
MTGWRIGYAAGSEPIIKAMTNLASHSTSNPTSVAQYGAIAAYNGPNEPVEEMRKAFEERLNKVYELLVDIPGLTCLKPEG
AFYLFPNAKKAAESCGFSSVDEFAEALLEEEKVAIVPGSGFGAPDNIRLSYATSLSLLEEAVERIRRFVVNRSR

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713254, Length=425, Percent_Identity=27.0588235294118, Blast_Score=174, Evalue=9e-44,
Organism=Homo sapiens, GI56713256, Length=425, Percent_Identity=27.0588235294118, Blast_Score=174, Evalue=9e-44,
Organism=Homo sapiens, GI95147551, Length=401, Percent_Identity=28.1795511221945, Blast_Score=168, Evalue=8e-42,
Organism=Homo sapiens, GI169881279, Length=401, Percent_Identity=28.1795511221945, Blast_Score=168, Evalue=8e-42,
Organism=Homo sapiens, GI169881281, Length=398, Percent_Identity=23.6180904522613, Blast_Score=125, Evalue=6e-29,
Organism=Homo sapiens, GI4507369, Length=381, Percent_Identity=26.246719160105, Blast_Score=123, Evalue=3e-28,
Organism=Homo sapiens, GI215599424, Length=369, Percent_Identity=23.0352303523035, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI19263340, Length=369, Percent_Identity=23.0352303523035, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI4885351, Length=362, Percent_Identity=24.585635359116, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI187936925, Length=232, Percent_Identity=27.1551724137931, Blast_Score=69, Evalue=8e-12,
Organism=Homo sapiens, GI14211921, Length=232, Percent_Identity=27.1551724137931, Blast_Score=69, Evalue=8e-12,
Organism=Escherichia coli, GI1788627, Length=385, Percent_Identity=28.3116883116883, Blast_Score=174, Evalue=1e-44,
Organism=Escherichia coli, GI1786816, Length=375, Percent_Identity=29.3333333333333, Blast_Score=161, Evalue=9e-41,
Organism=Escherichia coli, GI1788722, Length=387, Percent_Identity=30.749354005168, Blast_Score=149, Evalue=4e-37,
Organism=Escherichia coli, GI1787909, Length=380, Percent_Identity=22.6315789473684, Blast_Score=79, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17567663, Length=371, Percent_Identity=27.4932614555256, Blast_Score=146, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI17567369, Length=410, Percent_Identity=26.3414634146341, Blast_Score=140, Evalue=8e-34,
Organism=Caenorhabditis elegans, GI71994472, Length=421, Percent_Identity=26.8408551068884, Blast_Score=135, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI71994476, Length=421, Percent_Identity=26.8408551068884, Blast_Score=135, Evalue=5e-32,
Organism=Caenorhabditis elegans, GI71981209, Length=390, Percent_Identity=23.0769230769231, Blast_Score=82, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6322401, Length=419, Percent_Identity=30.0715990453461, Blast_Score=162, Evalue=7e-41,
Organism=Saccharomyces cerevisiae, GI6320317, Length=340, Percent_Identity=27.0588235294118, Blast_Score=102, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6323118, Length=368, Percent_Identity=26.6304347826087, Blast_Score=92, Evalue=1e-19,
Organism=Drosophila melanogaster, GI28573069, Length=420, Percent_Identity=26.1904761904762, Blast_Score=147, Evalue=1e-35,
Organism=Drosophila melanogaster, GI24646114, Length=420, Percent_Identity=26.1904761904762, Blast_Score=147, Evalue=1e-35,
Organism=Drosophila melanogaster, GI28573067, Length=420, Percent_Identity=26.1904761904762, Blast_Score=147, Evalue=1e-35,
Organism=Drosophila melanogaster, GI28573065, Length=420, Percent_Identity=26.1904761904762, Blast_Score=147, Evalue=1e-35,
Organism=Drosophila melanogaster, GI18859735, Length=382, Percent_Identity=24.6073298429319, Blast_Score=126, Evalue=3e-29,
Organism=Drosophila melanogaster, GI45551451, Length=362, Percent_Identity=25.6906077348066, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24641770, Length=362, Percent_Identity=25.6906077348066, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24641760, Length=362, Percent_Identity=25.6906077348066, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24641768, Length=362, Percent_Identity=25.6906077348066, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24641766, Length=362, Percent_Identity=25.6906077348066, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24641764, Length=362, Percent_Identity=25.6906077348066, Blast_Score=90, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 42911; Mature: 42911

Theoretical pI: Translated: 5.53; Mature: 5.53

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLAKRVSALTPSATLAITAKAKELKAAGHDVIGLGAGEPDFNTPEHIIEAAVRSMNEGH
CCHHHHHHHCCCCCEEEEEECHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHCCCC
TKYTPSGGLAALKDSIRDKFKRDQGIEYSQSEVIVCTGAKHALYTLFQVLLDEGDEVIIP
CEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHHHCCCCCEEEC
TPYWVSYPEQVKLAGGKPVFVEGLEENSFKISPEQLEKAVTEKTKAVIINSPSNPTGMMY
CCCCCCCCCCEEECCCCEEEEECCCCCCEEECHHHHHHHHHHCCCEEEEECCCCCCCCEE
TEEELKALGEVCLRRNVLIVSDEIYEKLIYGGKKHVSIAQLSPELKNQTVIINGVSKSHS
EHHHHHHHHHHHHHCCEEEECHHHHHHHHHCCCCCEEHHHCCCCCCCCEEEEECCCCCCC
MTGWRIGYAAGSEPIIKAMTNLASHSTSNPTSVAQYGAIAAYNGPNEPVEEMRKAFEERL
CCCEEEEECCCCCHHHHHHHHHHHCCCCCCCHHHHHCEEEEECCCCCHHHHHHHHHHHHH
NKVYELLVDIPGLTCLKPEGAFYLFPNAKKAAESCGFSSVDEFAEALLEEEKVAIVPGSG
HHHHHHHHCCCCCEEECCCCCEEECCCHHHHHHHCCCCCHHHHHHHHHCCCCEEEECCCC
FGAPDNIRLSYATSLSLLEEAVERIRRFVVNRSR
CCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNLAKRVSALTPSATLAITAKAKELKAAGHDVIGLGAGEPDFNTPEHIIEAAVRSMNEGH
CCHHHHHHHCCCCCEEEEEECHHHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHCCCC
TKYTPSGGLAALKDSIRDKFKRDQGIEYSQSEVIVCTGAKHALYTLFQVLLDEGDEVIIP
CEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCHHHHHHHHHHHHCCCCCEEEC
TPYWVSYPEQVKLAGGKPVFVEGLEENSFKISPEQLEKAVTEKTKAVIINSPSNPTGMMY
CCCCCCCCCCEEECCCCEEEEECCCCCCEEECHHHHHHHHHHCCCEEEEECCCCCCCCEE
TEEELKALGEVCLRRNVLIVSDEIYEKLIYGGKKHVSIAQLSPELKNQTVIINGVSKSHS
EHHHHHHHHHHHHHCCEEEECHHHHHHHHHCCCCCEEHHHCCCCCCCCEEEEECCCCCCC
MTGWRIGYAAGSEPIIKAMTNLASHSTSNPTSVAQYGAIAAYNGPNEPVEEMRKAFEERL
CCCEEEEECCCCCHHHHHHHHHHHCCCCCCCHHHHHCEEEEECCCCCHHHHHHHHHHHHH
NKVYELLVDIPGLTCLKPEGAFYLFPNAKKAAESCGFSSVDEFAEALLEEEKVAIVPGSG
HHHHHHHHCCCCCEEECCCCCEEECCCHHHHHHHCCCCCHHHHHHHHHCCCCEEEECCCC
FGAPDNIRLSYATSLSLLEEAVERIRRFVVNRSR
CCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8760912; 9384377 [H]