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The map label for this gene is ykrU [H]

Identifier: 52785278

GI number: 52785278

Start: 1487590

End: 1488369

Strand: Reverse

Name: ykrU [H]

Synonym: BLi01513

Alternate gene names: 52785278

Gene position: 1488369-1487590 (Counterclockwise)

Preceding gene: 52785283

Following gene: 52785277

Centisome position: 35.25

GC content: 51.15

Gene sequence:

>780_bases
GTGAAGCTGACAATTTCATGCCTGCAATTCGATATCGCGTACGGCAATCCTTCTGAAAATTTCAAAAAAGCGGAGCAGCT
GATCGAGCAGGAAAGCCGGAAGGCGGATATCCTTCTCCTTCCTGAGCTGTGGACGACGGGTTATGATTTAAAAAATCTCG
GCTCCATCGCGGATGAAGAAGGCAGGCAAACGAAGAGATGGCTGCAGGAAACGGCAAAAGCAAACCGCATCCATATCGTA
TGCGGCTCAGTCGCAGTCAAGAAAAAAAGCGGTGTGTACAATATCATGTACATCGCAGACAAAAACGGACATTTGATCAA
AGAATACAGCAAAGCTCACCTTTTTCAGCTGATGGACGAACACCTCTATTTGTCAGCGGGCTCAGGCGACGGGCGCTTCG
AGCTTGAAGGGATGCCGGCTGCGGGGTTCATCTGCTACGACATCCGTTTCCCGGAATGGATCAGAAAACATACGAGCGAA
GGTGCGGGCATCATCTTTGTATCGGCGGAGTGGCCGCTCGCCCGCCTCGATCACTGGCAAAGCCTTTTAAAAGCCAGAGC
GATTGAAAATCAGTGCTTTGTCGCAGCCTGCAATCGTTCGGGAAAAGACCCGGCAAACGAATTTGCGGGCCACAGCACAG
TCATTGATCCGCTCGGCCGCACCCTTGCTGAAGCAGGACGCGGAGAAGCGGTCATCAGGGCCGAAATCGACCTAAGGGAC
ATTGAAAAAGCGCGGGGGCAAATTCCGGTTTTTGAGGACATTCGCAAAGATTTATATTAA

Upstream 100 bases:

>100_bases
TTCATACGATTCACCCGCTTTTGAAAAATTCTTGAAATGATAGTCCATCATCATATATTGTTAAATGTAAAATGTAAAGA
AAAAAATGAGGTGATCCAGA

Downstream 100 bases:

>100_bases
AAAAATGTTGACAAGAAAACGGAGATGCTGGTAACATGTTCAGCAACTGACCGAACTGAAATTTCAAAATTTTATATTGA
TTTCTCTTATCGAGAGTTGG

Product: YkrU

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 259; Mature: 259

Protein sequence:

>259_residues
MKLTISCLQFDIAYGNPSENFKKAEQLIEQESRKADILLLPELWTTGYDLKNLGSIADEEGRQTKRWLQETAKANRIHIV
CGSVAVKKKSGVYNIMYIADKNGHLIKEYSKAHLFQLMDEHLYLSAGSGDGRFELEGMPAAGFICYDIRFPEWIRKHTSE
GAGIIFVSAEWPLARLDHWQSLLKARAIENQCFVAACNRSGKDPANEFAGHSTVIDPLGRTLAEAGRGEAVIRAEIDLRD
IEKARGQIPVFEDIRKDLY

Sequences:

>Translated_259_residues
MKLTISCLQFDIAYGNPSENFKKAEQLIEQESRKADILLLPELWTTGYDLKNLGSIADEEGRQTKRWLQETAKANRIHIV
CGSVAVKKKSGVYNIMYIADKNGHLIKEYSKAHLFQLMDEHLYLSAGSGDGRFELEGMPAAGFICYDIRFPEWIRKHTSE
GAGIIFVSAEWPLARLDHWQSLLKARAIENQCFVAACNRSGKDPANEFAGHSTVIDPLGRTLAEAGRGEAVIRAEIDLRD
IEKARGQIPVFEDIRKDLY
>Mature_259_residues
MKLTISCLQFDIAYGNPSENFKKAEQLIEQESRKADILLLPELWTTGYDLKNLGSIADEEGRQTKRWLQETAKANRIHIV
CGSVAVKKKSGVYNIMYIADKNGHLIKEYSKAHLFQLMDEHLYLSAGSGDGRFELEGMPAAGFICYDIRFPEWIRKHTSE
GAGIIFVSAEWPLARLDHWQSLLKARAIENQCFVAACNRSGKDPANEFAGHSTVIDPLGRTLAEAGRGEAVIRAEIDLRD
IEKARGQIPVFEDIRKDLY

Specific function: May be involved in a regulatory step in the methylthioribose (MTR) recycling pathway [H]

COG id: COG0388

COG function: function code R; Predicted amidohydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain [H]

Homologues:

Organism=Homo sapiens, GI9910460, Length=252, Percent_Identity=32.1428571428571, Blast_Score=130, Evalue=9e-31,
Organism=Homo sapiens, GI5031947, Length=264, Percent_Identity=29.5454545454545, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI297632350, Length=264, Percent_Identity=29.5454545454545, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI297632348, Length=264, Percent_Identity=29.5454545454545, Blast_Score=93, Evalue=2e-19,
Organism=Escherichia coli, GI1786412, Length=254, Percent_Identity=33.4645669291339, Blast_Score=137, Evalue=7e-34,
Organism=Caenorhabditis elegans, GI17556280, Length=266, Percent_Identity=32.3308270676692, Blast_Score=108, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6323383, Length=276, Percent_Identity=28.9855072463768, Blast_Score=113, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6322335, Length=288, Percent_Identity=27.0833333333333, Blast_Score=84, Evalue=3e-17,
Organism=Drosophila melanogaster, GI21355835, Length=238, Percent_Identity=29.8319327731092, Blast_Score=108, Evalue=3e-24,
Organism=Drosophila melanogaster, GI17933642, Length=258, Percent_Identity=29.0697674418605, Blast_Score=90, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003010 [H]

Pfam domain/function: PF00795 CN_hydrolase [H]

EC number: 3.5.-.- [C]

Molecular weight: Translated: 29172; Mature: 29172

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: PS50263 CN_HYDROLASE ; PS01227 UPF0012

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLTISCLQFDIAYGNPSENFKKAEQLIEQESRKADILLLPELWTTGYDLKNLGSIADEE
CEEEEEEEEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEECCHHCCCCCHHHHCCHHCCC
GRQTKRWLQETAKANRIHIVCGSVAVKKKSGVYNIMYIADKNGHLIKEYSKAHLFQLMDE
CHHHHHHHHHHHCCCEEEEEECCEEEECCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHH
HLYLSAGSGDGRFELEGMPAAGFICYDIRFPEWIRKHTSEGAGIIFVSAEWPLARLDHWQ
HEEEEECCCCCEEEECCCCCCCEEEEECCCHHHHHHHCCCCCEEEEEECCCCHHHHHHHH
SLLKARAIENQCFVAACNRSGKDPANEFAGHSTVIDPLGRTLAEAGRGEAVIRAEIDLRD
HHHHHHHHCCCEEEEECCCCCCCHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEEECCHHH
IEKARGQIPVFEDIRKDLY
HHHHCCCCCCHHHHHHHCC
>Mature Secondary Structure
MKLTISCLQFDIAYGNPSENFKKAEQLIEQESRKADILLLPELWTTGYDLKNLGSIADEE
CEEEEEEEEEEEECCCCCHHHHHHHHHHHHHCCCCCEEEECCHHCCCCCHHHHCCHHCCC
GRQTKRWLQETAKANRIHIVCGSVAVKKKSGVYNIMYIADKNGHLIKEYSKAHLFQLMDE
CHHHHHHHHHHHCCCEEEEEECCEEEECCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHH
HLYLSAGSGDGRFELEGMPAAGFICYDIRFPEWIRKHTSEGAGIIFVSAEWPLARLDHWQ
HEEEEECCCCCEEEECCCCCCCEEEEECCCHHHHHHHCCCCCEEEEEECCCCHHHHHHHH
SLLKARAIENQCFVAACNRSGKDPANEFAGHSTVIDPLGRTLAEAGRGEAVIRAEIDLRD
HHHHHHHHCCCEEEEECCCCCCCHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEEECCHHH
IEKARGQIPVFEDIRKDLY
HHHHCCCCCCHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 12022921 [H]