Click here to switch to the map view.

The map label for this gene is mtnK

Identifier: 52785277

GI number: 52785277

Start: 1486082

End: 1487278

Strand: Reverse

Name: mtnK

Synonym: BLi01512

Alternate gene names: 52785277

Gene position: 1487278-1486082 (Counterclockwise)

Preceding gene: 52785278

Following gene: 52785276

Centisome position: 35.22

GC content: 51.13

Gene sequence:

>1197_bases
ATGACCGTAACAAAAACCGCAGCATACGAAACTTTGACTGAAAGCTCCGCGGCCGCGCTTGCCGTCCGTCTCGGGCTTTT
TCCAAGCAAAAGCACCCTGACATGCCGAGAGATCGGGGACGGAAACCTGAATCTGGTCTTCCGCGTTTATGACAAAGAGC
AGCAAAGAGGATTGGTCATCAAGCAGGCGGTGCCTTATGCAAAAGTCGTCGGCGAAAGCTGGCCGCTGACGCTTGACAGG
GCAAGAATCGAAAGCAGTGCGCTGATCCGCCAGGCTGAGCACGTTCCGCACCTTGTTCCGAAAGTGTACTATTCTGACAC
CGAGCTTGCCGTCACCGTATTGGAAGACCTTTCTCACTTGGAAATCGCCAGAAACGGACTGATTGACGGGAAGGATTACC
CGCATCTGTCGGAAGATATCGGAGAATTCCTTGGAAAAACGCATTTTTACTCATCAGAATATGCGCTTGACCCAACGGTT
AAAGAGCGGCTTGTGAAGCAGTTTACGAATCCGGATCTGTGCGATATTACAGAAAGCCTTGTGTTCACAGACCCTTTCTT
TGACCATGAGACGAACGATTTCGAAGAAGAGCTTCGCGATGAAGCAGAAGTTCTTTGGGGCAATGAAGCGCTAAAAATTG
AAGCGGCAAAACTGAAGCAGCGCTTTTTATCAGCGGAGGAAACGCTGATCCACGGAGACCTGCATACAGGCAGCATTTTC
GCCGGTGAAGATGGCGAAACGAAAATCATCGACCCTGAGTTTGCGTTTTTCGGCCCGATCGGGTTTGACATCGGACAGTT
TATCGCCAACCTGCTGTTAAACGCGCTTTCTCGCGAAGAAAACAGGCGGGCTCCTTTATACCGCCATGTTGAGACCGTCT
GGAATACGTTCAGCCGGACATTCAGCGAAGCATGGGAAAACGATGCTGTTGAGACTTGCAAACATGAGAATGGGCGCCTT
GAGTCAGTCCTGAGACAGGCGTTTGAAGACGCAGCAGGCTTCGCCGGCTGCGAAATGATCCGCCGGACGATCGGCCTCGC
CCATGTTGCGGACCTTGATACAATCGTTCCATTTTCCCGGAGAATCAGCCAAAAAAAGCTCGCCCTTAAAATAGGCGCAG
CATTCATAGAAAAACGCAGCGGTTTCCGGACGCCAAAAGACATGATTGAAGCGTTTCGAAACGCGCTTAAGGAGTGA

Upstream 100 bases:

>100_bases
TTCTGAGAGATAAGAGAGGCGTACGCGACAAATCAGCCTCTTTCTCTCGACGAGAAAGAGGTTTTTTTATTTGTTAACGA
CATTTTAGGGGGAATCACAC

Downstream 100 bases:

>100_bases
ATGACATGCCGGAACAATTTGCGGTGCCCCGTTCTGTCGAATGGGAAGAAACATCGGTAAAAATCCTGAACCAGCAAAAG
CTTCCCGAAAAGACGGAGTA

Product: methylthioribose kinase

Products: NA

Alternate protein names: MTR kinase

Number of amino acids: Translated: 398; Mature: 397

Protein sequence:

>398_residues
MTVTKTAAYETLTESSAAALAVRLGLFPSKSTLTCREIGDGNLNLVFRVYDKEQQRGLVIKQAVPYAKVVGESWPLTLDR
ARIESSALIRQAEHVPHLVPKVYYSDTELAVTVLEDLSHLEIARNGLIDGKDYPHLSEDIGEFLGKTHFYSSEYALDPTV
KERLVKQFTNPDLCDITESLVFTDPFFDHETNDFEEELRDEAEVLWGNEALKIEAAKLKQRFLSAEETLIHGDLHTGSIF
AGEDGETKIIDPEFAFFGPIGFDIGQFIANLLLNALSREENRRAPLYRHVETVWNTFSRTFSEAWENDAVETCKHENGRL
ESVLRQAFEDAAGFAGCEMIRRTIGLAHVADLDTIVPFSRRISQKKLALKIGAAFIEKRSGFRTPKDMIEAFRNALKE

Sequences:

>Translated_398_residues
MTVTKTAAYETLTESSAAALAVRLGLFPSKSTLTCREIGDGNLNLVFRVYDKEQQRGLVIKQAVPYAKVVGESWPLTLDR
ARIESSALIRQAEHVPHLVPKVYYSDTELAVTVLEDLSHLEIARNGLIDGKDYPHLSEDIGEFLGKTHFYSSEYALDPTV
KERLVKQFTNPDLCDITESLVFTDPFFDHETNDFEEELRDEAEVLWGNEALKIEAAKLKQRFLSAEETLIHGDLHTGSIF
AGEDGETKIIDPEFAFFGPIGFDIGQFIANLLLNALSREENRRAPLYRHVETVWNTFSRTFSEAWENDAVETCKHENGRL
ESVLRQAFEDAAGFAGCEMIRRTIGLAHVADLDTIVPFSRRISQKKLALKIGAAFIEKRSGFRTPKDMIEAFRNALKE
>Mature_397_residues
TVTKTAAYETLTESSAAALAVRLGLFPSKSTLTCREIGDGNLNLVFRVYDKEQQRGLVIKQAVPYAKVVGESWPLTLDRA
RIESSALIRQAEHVPHLVPKVYYSDTELAVTVLEDLSHLEIARNGLIDGKDYPHLSEDIGEFLGKTHFYSSEYALDPTVK
ERLVKQFTNPDLCDITESLVFTDPFFDHETNDFEEELRDEAEVLWGNEALKIEAAKLKQRFLSAEETLIHGDLHTGSIFA
GEDGETKIIDPEFAFFGPIGFDIGQFIANLLLNALSREENRRAPLYRHVETVWNTFSRTFSEAWENDAVETCKHENGRLE
SVLRQAFEDAAGFAGCEMIRRTIGLAHVADLDTIVPFSRRISQKKLALKIGAAFIEKRSGFRTPKDMIEAFRNALKE

Specific function: Catalyzes the phosphorylation of methylthioribose into methylthioribose-1-phosphate

COG id: COG4857

COG function: function code R; Predicted kinase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methylthioribose kinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MTNK_BACLD (Q65KK1)

Other databases:

- EMBL:   CP000002
- EMBL:   AE017333
- RefSeq:   YP_078697.1
- RefSeq:   YP_091106.1
- ProteinModelPortal:   Q65KK1
- SMR:   Q65KK1
- STRING:   Q65KK1
- EnsemblBacteria:   EBBACT00000056692
- EnsemblBacteria:   EBBACT00000059316
- GeneID:   3030592
- GeneID:   3100555
- GenomeReviews:   AE017333_GR
- GenomeReviews:   CP000002_GR
- KEGG:   bld:BLi01512
- KEGG:   bli:BL03633
- NMPDR:   fig|279010.5.peg.1064
- eggNOG:   COG4857
- GeneTree:   EBGT00050000001231
- HOGENOM:   HBG305135
- OMA:   ALPYVRL
- ProtClustDB:   PRK09550
- BioCyc:   BLIC279010-1:BLI01512-MONOMER
- BioCyc:   BLIC279010:BL03633-MONOMER
- HAMAP:   MF_01683
- InterPro:   IPR002575
- InterPro:   IPR011009
- InterPro:   IPR009212
- PIRSF:   PIRSF031134
- TIGRFAMs:   TIGR01767

Pfam domain/function: PF01636 APH; SSF56112 Kinase_like

EC number: =2.7.1.100

Molecular weight: Translated: 44849; Mature: 44718

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: BINDING 44-44 BINDING 61-61 BINDING 233-233 BINDING 341-341

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVTKTAAYETLTESSAAALAVRLGLFPSKSTLTCREIGDGNLNLVFRVYDKEQQRGLVI
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHCCCCCCEEEEEEEECCCCCCCEEH
KQAVPYAKVVGESWPLTLDRARIESSALIRQAEHVPHLVPKVYYSDTELAVTVLEDLSHL
HHHCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHEECCCHHHHHHHHHHHHH
EIARNGLIDGKDYPHLSEDIGEFLGKTHFYSSEYALDPTVKERLVKQFTNPDLCDITESL
HHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHH
VFTDPFFDHETNDFEEELRDEAEVLWGNEALKIEAAKLKQRFLSAEETLIHGDLHTGSIF
HCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHEEECCCCCCCEE
AGEDGETKIIDPEFAFFGPIGFDIGQFIANLLLNALSREENRRAPLYRHVETVWNTFSRT
ECCCCCCEEECCCHHEECCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
FSEAWENDAVETCKHENGRLESVLRQAFEDAAGFAGCEMIRRTIGLAHVADLDTIVPFSR
HHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RISQKKLALKIGAAFIEKRSGFRTPKDMIEAFRNALKE
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
TVTKTAAYETLTESSAAALAVRLGLFPSKSTLTCREIGDGNLNLVFRVYDKEQQRGLVI
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHCCCCCCEEEEEEEECCCCCCCEEH
KQAVPYAKVVGESWPLTLDRARIESSALIRQAEHVPHLVPKVYYSDTELAVTVLEDLSHL
HHHCCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHEECCCHHHHHHHHHHHHH
EIARNGLIDGKDYPHLSEDIGEFLGKTHFYSSEYALDPTVKERLVKQFTNPDLCDITESL
HHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHH
VFTDPFFDHETNDFEEELRDEAEVLWGNEALKIEAAKLKQRFLSAEETLIHGDLHTGSIF
HCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHEEECCCCCCCEE
AGEDGETKIIDPEFAFFGPIGFDIGQFIANLLLNALSREENRRAPLYRHVETVWNTFSRT
ECCCCCCEEECCCHHEECCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
FSEAWENDAVETCKHENGRLESVLRQAFEDAAGFAGCEMIRRTIGLAHVADLDTIVPFSR
HHHHHCCHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RISQKKLALKIGAAFIEKRSGFRTPKDMIEAFRNALKE
HHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA