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The map label for this gene is acoB [H]

Identifier: 52784648

GI number: 52784648

Start: 868558

End: 869592

Strand: Direct

Name: acoB [H]

Synonym: BLi00850

Alternate gene names: 52784648

Gene position: 868558-869592 (Clockwise)

Preceding gene: 52784647

Following gene: 52784649

Centisome position: 20.57

GC content: 52.56

Gene sequence:

>1035_bases
ATGACGAGGGAAATCAGCATGTCAGCCGCATTGAATGAAGCGATCAAACTTGCGATGAGAAGGGACGATCACGTCATTTT
AATGGGGGAAGATGTCGCAGGAGGAGCGAATGTCGATCATCTGCAGGATGATGAAGCATGGGGCGGTGTGCTCGGCGTCA
CGAAAGGGATTGTTCAGGAATTTGGACGGGAGCGCGTCCTTGATACGCCGATCAGTGAAGCGGGGTACATCGGCGCAGCC
ATGGCTGCTGCTTCAACCGGTTTAAGGCCGATCGCGGAATTGATGTTTAACGATTTTATCGGAACATGTTTGGACCAGGT
GCTGAACCAGGGAGCGAAATTCCGCTACATGTTTGGCGGCAAAGCGGAAGTTCCGATTACGATCCGGACGACCCACGGCG
CCGGCTTTAGGGCGGCCGCCCAGCATTCGCAAAGCTTGTATGCCCTATTTACAAGCATTCCCGGACTGAAAGTGATTGTG
CCGTCGACCCCGTACGACGCAAAAGGATTATTGCTCGCTGCGATTGAAGATCAGGACCCGGTTATCTTTTTTGAAGACAA
AACGCTGTACAACATGACAGGCGATGTGCCGGAAGAATATTACACGCTTCCAATCGGAAAAGCAGATATCAAGCGGAAAG
GCGCCGATGTAACGATTGTTGCAATCGGCAAACAGGTTCATACGGCGCTTCAAGCGGCGGAACAGCTCTCAGCGCGGGGA
ATCGAAGCCGAAATCCTTGATCCGCGAAGCCTTTCGCCGCTTGATGAAGAGGCCGTCCTTGCATCCGTAGAAAAAACAAA
CAGGCTTGTGATCGTCGATGAGGCCAATCCGAGATGCAGCATCGCCGCGGATATCGCATCATTGGCGGCAGATAAAGGAT
TTGATTCGCTTGACGCACCGGTTAAAAAGGTGACGGCTCCGCATACGCCGGTGCCATTTTCACCGCCTCTTGAAGACCTG
TATTTGCCGACGCCGGAAAAAGTCGTGAACACCGTGCTTGAGATGCTCGGAGAAACATCAACACATACGGTGTAA

Upstream 100 bases:

>100_bases
GGAAGCGGTCGCATTCAGCGAAAAAAGCGCTTATCCGGAAGAAACCGAACTGCTGACGGATGTATATGTATCCTATTAAT
TCATGAAGGGGGAAGGAAAC

Downstream 100 bases:

>100_bases
AGATTGGAAAGGAGAGGAGAACATGGCTGTCGAAGTGGTCATGCCGAAATTGGGGATGTCGATGAAAGAAGGTACGGTTT
CCGTCTGGAATAAAAAAGTC

Product: hypothetical protein

Products: CO2; deoxyxylulose-5-phosphate [C]

Alternate protein names: Acetoin:DCPIP oxidoreductase-beta; Ao:DCPIP OR; TPP-dependent acetoin dehydrogenase E1 subunit beta [H]

Number of amino acids: Translated: 344; Mature: 343

Protein sequence:

>344_residues
MTREISMSAALNEAIKLAMRRDDHVILMGEDVAGGANVDHLQDDEAWGGVLGVTKGIVQEFGRERVLDTPISEAGYIGAA
MAAASTGLRPIAELMFNDFIGTCLDQVLNQGAKFRYMFGGKAEVPITIRTTHGAGFRAAAQHSQSLYALFTSIPGLKVIV
PSTPYDAKGLLLAAIEDQDPVIFFEDKTLYNMTGDVPEEYYTLPIGKADIKRKGADVTIVAIGKQVHTALQAAEQLSARG
IEAEILDPRSLSPLDEEAVLASVEKTNRLVIVDEANPRCSIAADIASLAADKGFDSLDAPVKKVTAPHTPVPFSPPLEDL
YLPTPEKVVNTVLEMLGETSTHTV

Sequences:

>Translated_344_residues
MTREISMSAALNEAIKLAMRRDDHVILMGEDVAGGANVDHLQDDEAWGGVLGVTKGIVQEFGRERVLDTPISEAGYIGAA
MAAASTGLRPIAELMFNDFIGTCLDQVLNQGAKFRYMFGGKAEVPITIRTTHGAGFRAAAQHSQSLYALFTSIPGLKVIV
PSTPYDAKGLLLAAIEDQDPVIFFEDKTLYNMTGDVPEEYYTLPIGKADIKRKGADVTIVAIGKQVHTALQAAEQLSARG
IEAEILDPRSLSPLDEEAVLASVEKTNRLVIVDEANPRCSIAADIASLAADKGFDSLDAPVKKVTAPHTPVPFSPPLEDL
YLPTPEKVVNTVLEMLGETSTHTV
>Mature_343_residues
TREISMSAALNEAIKLAMRRDDHVILMGEDVAGGANVDHLQDDEAWGGVLGVTKGIVQEFGRERVLDTPISEAGYIGAAM
AAASTGLRPIAELMFNDFIGTCLDQVLNQGAKFRYMFGGKAEVPITIRTTHGAGFRAAAQHSQSLYALFTSIPGLKVIVP
STPYDAKGLLLAAIEDQDPVIFFEDKTLYNMTGDVPEEYYTLPIGKADIKRKGADVTIVAIGKQVHTALQAAEQLSARGI
EAEILDPRSLSPLDEEAVLASVEKTNRLVIVDEANPRCSIAADIASLAADKGFDSLDAPVKKVTAPHTPVPFSPPLEDLY
LPTPEKVVNTVLEMLGETSTHTV

Specific function: Catalyzes the 2,6-dichlorophenolindophenol-dependent cleavage of acetoin into acetate and acetaldehyde [H]

COG id: COG0022

COG function: function code C; Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI156564403, Length=338, Percent_Identity=37.5739644970414, Blast_Score=236, Evalue=3e-62,
Organism=Homo sapiens, GI4557353, Length=338, Percent_Identity=35.5029585798817, Blast_Score=220, Evalue=2e-57,
Organism=Homo sapiens, GI34101272, Length=338, Percent_Identity=35.5029585798817, Blast_Score=220, Evalue=2e-57,
Organism=Homo sapiens, GI291084858, Length=338, Percent_Identity=35.5029585798817, Blast_Score=215, Evalue=4e-56,
Organism=Caenorhabditis elegans, GI17538422, Length=332, Percent_Identity=42.7710843373494, Blast_Score=254, Evalue=7e-68,
Organism=Caenorhabditis elegans, GI17506935, Length=333, Percent_Identity=40.5405405405405, Blast_Score=226, Evalue=1e-59,
Organism=Saccharomyces cerevisiae, GI6319698, Length=341, Percent_Identity=40.1759530791789, Blast_Score=249, Evalue=4e-67,
Organism=Drosophila melanogaster, GI21358145, Length=340, Percent_Identity=39.1176470588235, Blast_Score=246, Evalue=2e-65,
Organism=Drosophila melanogaster, GI24650940, Length=340, Percent_Identity=39.1176470588235, Blast_Score=246, Evalue=2e-65,
Organism=Drosophila melanogaster, GI160714832, Length=337, Percent_Identity=37.9821958456973, Blast_Score=222, Evalue=2e-58,
Organism=Drosophila melanogaster, GI160714828, Length=337, Percent_Identity=37.9821958456973, Blast_Score=222, Evalue=3e-58,
Organism=Drosophila melanogaster, GI24650943, Length=104, Percent_Identity=34.6153846153846, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24650945, Length=104, Percent_Identity=34.6153846153846, Blast_Score=72, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005475
- InterPro:   IPR005476 [H]

Pfam domain/function: PF02779 Transket_pyr; PF02780 Transketolase_C [H]

EC number: 2.2.1.7 [C]

Molecular weight: Translated: 36885; Mature: 36754

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTREISMSAALNEAIKLAMRRDDHVILMGEDVAGGANVDHLQDDEAWGGVLGVTKGIVQE
CCCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
FGRERVLDTPISEAGYIGAAMAAASTGLRPIAELMFNDFIGTCLDQVLNQGAKFRYMFGG
HCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECC
KAEVPITIRTTHGAGFRAAAQHSQSLYALFTSIPGLKVIVPSTPYDAKGLLLAAIEDQDP
CCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCEEEEEECCCCC
VIFFEDKTLYNMTGDVPEEYYTLPIGKADIKRKGADVTIVAIGKQVHTALQAAEQLSARG
EEEEECCEEEECCCCCCCCEEEECCCHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHCC
IEAEILDPRSLSPLDEEAVLASVEKTNRLVIVDEANPRCSIAADIASLAADKGFDSLDAP
CCEEEECCCCCCCCCHHHHHHHHHHCCEEEEEECCCCCEEHHHHHHHHHHHCCCCHHCCC
VKKVTAPHTPVPFSPPLEDLYLPTPEKVVNTVLEMLGETSTHTV
HHHHCCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TREISMSAALNEAIKLAMRRDDHVILMGEDVAGGANVDHLQDDEAWGGVLGVTKGIVQE
CCCCHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
FGRERVLDTPISEAGYIGAAMAAASTGLRPIAELMFNDFIGTCLDQVLNQGAKFRYMFGG
HCCCCCCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECC
KAEVPITIRTTHGAGFRAAAQHSQSLYALFTSIPGLKVIVPSTPYDAKGLLLAAIEDQDP
CCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCEEEEEECCCCC
VIFFEDKTLYNMTGDVPEEYYTLPIGKADIKRKGADVTIVAIGKQVHTALQAAEQLSARG
EEEEECCEEEECCCCCCCCEEEECCCHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHCC
IEAEILDPRSLSPLDEEAVLASVEKTNRLVIVDEANPRCSIAADIASLAADKGFDSLDAP
CCEEEECCCCCCCCCHHHHHHHHHHCCEEEEEECCCCCEEHHHHHHHHHHHCCCCHHCCC
VKKVTAPHTPVPFSPPLEDLYLPTPEKVVNTVLEMLGETSTHTV
HHHHCCCCCCCCCCCCHHHCCCCCHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: pyruvate; glyceraldehyde-3-phosphate [C]

Specific reaction: pyruvate + glyceraldehyde-3-phosphate = CO2 + deoxyxylulose-5-phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10368162; 8969503; 9384377 [H]