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The map label for this gene is ysfC [H]

Identifier: 52784153

GI number: 52784153

Start: 305781

End: 307193

Strand: Reverse

Name: ysfC [H]

Synonym: BLi00330

Alternate gene names: 52784153

Gene position: 307193-305781 (Counterclockwise)

Preceding gene: 52784154

Following gene: 52784152

Centisome position: 7.27

GC content: 49.68

Gene sequence:

>1413_bases
ATGATTTCCTCACAAGTGAGATCCAAGCTGATTGAGATTGTCGGCTCTGCCAATTATGACGATTCGAACGCCGGACGGCT
CGTCTATTCCTATGATGCGACACCACAGTTTCAATCGATGCCTGACGCGGTCATTGCCCCGCGCAGCAAGGAAGAAGTAT
CGCGAATCGTGAAAATCTGCAACACGCACCGCATTCCGATTGTGCCGAGAGGTTCAGGTACAAACCTATGTGCCGGCACA
TGCCCGACTGAAGGGGGGATTGTCCTCCTGTTTAAGCATATGAATCAAATTTTAGAAATCGATGAAGAAAATTTAACGAT
AACCGTCCAGCCCGGTGTGATCACACTTGACTTAATTCACGCCGCTGAAGAAAAAGGATTATTTTATCCGCCCGATCCGA
GCTCAATGAAGATCTCGACAATCGGCGGGAATATTAACGAAAACTCAGGCGGCCTCCGCGGCTTGAAATACGGAGTGACC
CGCGATTATGTCATGGCGCTGGAAATCGTTCTTGCAAACGGGGACATCATCCGCACCGGCGGCAAGCTGGCCAAAGATGT
TGCCGGCTATGATTTGACGCGTCTGTTCGTCGGTTCTGAAGGAACGCTCGGCGTCATCACTGAAGCAACATTAAAACTCA
TCCCGGCACCCGAAACAAAAAAAACCGTCCTCGCTCTCTATCAAGATATCGACTCTGCAGCACAAACTGTTTCAAATATC
ATTGCACATAAAATCATTCCGACGACACTCGAATTTCTCGACCAACCTACGATTCAGGTGATCGAAGACTTCGCGAAAAT
CGGCCTTCCCGTCCATGCCAAAGCGGTTCTCCTGATCGAACAGGACGGCACCGAAGATGCAGTTCGCCGTGATATCGCCG
TGATTGAAGAGATTTGCAAAAAAGGAAATGCTGTGTCCGTTCAAACTGCGCAAACAGAAGCTGAAGCGGAAAATCTTCGG
GAGGCCCGCCGCACCGCCCTTTCGGCTTTAGCGCGGTTAAAGCCGACGACCATTCTGGAGGATGCTACGGTACCGCGTTC
TGAAATTGCTGAAATGGTAAAAGCGATTAATTCGATCGCCGAAAAGCACCAAATATCGATTTGTACATTCGGGCACGCAG
GCGACGGCAACCTTCATCCGACCTGTACGACAGATGTCAGAAACAGTGAAGAAATGAAACGGGTCGAACAGGCTTTTGAA
GACATCTTTAAAAAAGCGGTTGAACTGGGAGGAACAATTACCGGAGAACATGGGGTCGGCGAAATGAAAGCCCCCTATTT
GGAACTGAAGCTGGGCAATGCGGGAATCGCCGCCATGAAGGCGGTAAAACAGGCATTGGATCCAAACAACATCATGAATC
CCGGGAAGATATTTGCGAAAGACTCCCGCAAGCGAGTGGTGGTGACAAGATGA

Upstream 100 bases:

>100_bases
TCCTTTGAAAACGGGTTCTTTTTTATATTTGAAGTTTAAAAGAATGATTTTTTGAAAGCGTTTGATTTTGTATAATAATT
GGTAAAGGATGTGATCATAC

Downstream 100 bases:

>100_bases
CGACAGCTGACGAAAGAAAGGTCATTGAACAGCAGTTTAAACAAAGAATGGATGAGGAAGAGCTGCTGAATTGCATGCGC
TGCGGCTTCTGTCTGCCGTC

Product: YsfC

Products: 2-oxo acid; H2O2

Alternate protein names: NA

Number of amino acids: Translated: 470; Mature: 470

Protein sequence:

>470_residues
MISSQVRSKLIEIVGSANYDDSNAGRLVYSYDATPQFQSMPDAVIAPRSKEEVSRIVKICNTHRIPIVPRGSGTNLCAGT
CPTEGGIVLLFKHMNQILEIDEENLTITVQPGVITLDLIHAAEEKGLFYPPDPSSMKISTIGGNINENSGGLRGLKYGVT
RDYVMALEIVLANGDIIRTGGKLAKDVAGYDLTRLFVGSEGTLGVITEATLKLIPAPETKKTVLALYQDIDSAAQTVSNI
IAHKIIPTTLEFLDQPTIQVIEDFAKIGLPVHAKAVLLIEQDGTEDAVRRDIAVIEEICKKGNAVSVQTAQTEAEAENLR
EARRTALSALARLKPTTILEDATVPRSEIAEMVKAINSIAEKHQISICTFGHAGDGNLHPTCTTDVRNSEEMKRVEQAFE
DIFKKAVELGGTITGEHGVGEMKAPYLELKLGNAGIAAMKAVKQALDPNNIMNPGKIFAKDSRKRVVVTR

Sequences:

>Translated_470_residues
MISSQVRSKLIEIVGSANYDDSNAGRLVYSYDATPQFQSMPDAVIAPRSKEEVSRIVKICNTHRIPIVPRGSGTNLCAGT
CPTEGGIVLLFKHMNQILEIDEENLTITVQPGVITLDLIHAAEEKGLFYPPDPSSMKISTIGGNINENSGGLRGLKYGVT
RDYVMALEIVLANGDIIRTGGKLAKDVAGYDLTRLFVGSEGTLGVITEATLKLIPAPETKKTVLALYQDIDSAAQTVSNI
IAHKIIPTTLEFLDQPTIQVIEDFAKIGLPVHAKAVLLIEQDGTEDAVRRDIAVIEEICKKGNAVSVQTAQTEAEAENLR
EARRTALSALARLKPTTILEDATVPRSEIAEMVKAINSIAEKHQISICTFGHAGDGNLHPTCTTDVRNSEEMKRVEQAFE
DIFKKAVELGGTITGEHGVGEMKAPYLELKLGNAGIAAMKAVKQALDPNNIMNPGKIFAKDSRKRVVVTR
>Mature_470_residues
MISSQVRSKLIEIVGSANYDDSNAGRLVYSYDATPQFQSMPDAVIAPRSKEEVSRIVKICNTHRIPIVPRGSGTNLCAGT
CPTEGGIVLLFKHMNQILEIDEENLTITVQPGVITLDLIHAAEEKGLFYPPDPSSMKISTIGGNINENSGGLRGLKYGVT
RDYVMALEIVLANGDIIRTGGKLAKDVAGYDLTRLFVGSEGTLGVITEATLKLIPAPETKKTVLALYQDIDSAAQTVSNI
IAHKIIPTTLEFLDQPTIQVIEDFAKIGLPVHAKAVLLIEQDGTEDAVRRDIAVIEEICKKGNAVSVQTAQTEAEAENLR
EARRTALSALARLKPTTILEDATVPRSEIAEMVKAINSIAEKHQISICTFGHAGDGNLHPTCTTDVRNSEEMKRVEQAFE
DIFKKAVELGGTITGEHGVGEMKAPYLELKLGNAGIAAMKAVKQALDPNNIMNPGKIFAKDSRKRVVVTR

Specific function: Unknown

COG id: COG0277

COG function: function code C; FAD/FMN-containing dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Homo sapiens, GI37595756, Length=454, Percent_Identity=32.3788546255507, Blast_Score=260, Evalue=2e-69,
Organism=Homo sapiens, GI37595754, Length=477, Percent_Identity=30.8176100628931, Blast_Score=250, Evalue=2e-66,
Organism=Homo sapiens, GI119964728, Length=419, Percent_Identity=28.4009546539379, Blast_Score=171, Evalue=9e-43,
Organism=Homo sapiens, GI4501993, Length=228, Percent_Identity=31.5789473684211, Blast_Score=121, Evalue=2e-27,
Organism=Escherichia coli, GI1789351, Length=428, Percent_Identity=37.6168224299065, Blast_Score=310, Evalue=1e-85,
Organism=Escherichia coli, GI1787977, Length=515, Percent_Identity=27.5728155339806, Blast_Score=171, Evalue=8e-44,
Organism=Escherichia coli, GI48994907, Length=442, Percent_Identity=28.0542986425339, Blast_Score=125, Evalue=7e-30,
Organism=Escherichia coli, GI48994914, Length=348, Percent_Identity=26.7241379310345, Blast_Score=91, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71992373, Length=455, Percent_Identity=33.6263736263736, Blast_Score=249, Evalue=2e-66,
Organism=Caenorhabditis elegans, GI71992381, Length=455, Percent_Identity=32.967032967033, Blast_Score=234, Evalue=1e-61,
Organism=Caenorhabditis elegans, GI71992392, Length=382, Percent_Identity=33.5078534031414, Blast_Score=207, Evalue=1e-53,
Organism=Caenorhabditis elegans, GI17534361, Length=437, Percent_Identity=27.6887871853547, Blast_Score=176, Evalue=2e-44,
Organism=Caenorhabditis elegans, GI17556096, Length=468, Percent_Identity=24.1452991452991, Blast_Score=137, Evalue=9e-33,
Organism=Saccharomyces cerevisiae, GI6320027, Length=481, Percent_Identity=31.6008316008316, Blast_Score=215, Evalue=1e-56,
Organism=Saccharomyces cerevisiae, GI6320764, Length=445, Percent_Identity=27.6404494382022, Blast_Score=179, Evalue=1e-45,
Organism=Saccharomyces cerevisiae, GI6320023, Length=453, Percent_Identity=28.6975717439294, Blast_Score=177, Evalue=5e-45,
Organism=Drosophila melanogaster, GI18921117, Length=429, Percent_Identity=28.6713286713287, Blast_Score=183, Evalue=2e-46,
Organism=Drosophila melanogaster, GI24639277, Length=429, Percent_Identity=28.6713286713287, Blast_Score=183, Evalue=2e-46,
Organism=Drosophila melanogaster, GI24639275, Length=429, Percent_Identity=28.6713286713287, Blast_Score=183, Evalue=2e-46,
Organism=Drosophila melanogaster, GI24653753, Length=503, Percent_Identity=24.8508946322068, Blast_Score=131, Evalue=8e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR016164
- InterPro:   IPR016168
- InterPro:   IPR004113
- InterPro:   IPR004490
- InterPro:   IPR006094
- InterPro:   IPR016171 [H]

Pfam domain/function: PF02913 FAD-oxidase_C; PF01565 FAD_binding_4 [H]

EC number: 1.1.3.15

Molecular weight: Translated: 50802; Mature: 50802

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISSQVRSKLIEIVGSANYDDSNAGRLVYSYDATPQFQSMPDAVIAPRSKEEVSRIVKIC
CCCHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCHHCCCCHHCCCCCHHHHHHHHHHH
NTHRIPIVPRGSGTNLCAGTCPTEGGIVLLFKHMNQILEIDEENLTITVQPGVITLDLIH
CCCCCEEEECCCCCCEEECCCCCCCCEEEHHHHHHHHHCCCCCCEEEEEECCEEEEEEEH
AAEEKGLFYPPDPSSMKISTIGGNINENSGGLRGLKYGVTRDYVMALEIVLANGDIIRTG
HHHHCCCCCCCCCCCEEEEEECCCCCCCCCCCCCEECCCCHHHHEEEEEEEECCCEEECC
GKLAKDVAGYDLTRLFVGSEGTLGVITEATLKLIPAPETKKTVLALYQDIDSAAQTVSNI
CHHHHHHCCCCEEEEEECCCCCEEEEEHEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
IAHKIIPTTLEFLDQPTIQVIEDFAKIGLPVHAKAVLLIEQDGTEDAVRRDIAVIEEICK
HHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHH
KGNAVSVQTAQTEAEAENLREARRTALSALARLKPTTILEDATVPRSEIAEMVKAINSIA
CCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCHHHHHHHHHHHHHHH
EKHQISICTFGHAGDGNLHPTCTTDVRNSEEMKRVEQAFEDIFKKAVELGGTITGEHGVG
HHHEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCC
EMKAPYLELKLGNAGIAAMKAVKQALDPNNIMNPGKIFAKDSRKRVVVTR
CCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCEEECCCCCEEEEEC
>Mature Secondary Structure
MISSQVRSKLIEIVGSANYDDSNAGRLVYSYDATPQFQSMPDAVIAPRSKEEVSRIVKIC
CCCHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCHHCCCCHHCCCCCHHHHHHHHHHH
NTHRIPIVPRGSGTNLCAGTCPTEGGIVLLFKHMNQILEIDEENLTITVQPGVITLDLIH
CCCCCEEEECCCCCCEEECCCCCCCCEEEHHHHHHHHHCCCCCCEEEEEECCEEEEEEEH
AAEEKGLFYPPDPSSMKISTIGGNINENSGGLRGLKYGVTRDYVMALEIVLANGDIIRTG
HHHHCCCCCCCCCCCEEEEEECCCCCCCCCCCCCEECCCCHHHHEEEEEEEECCCEEECC
GKLAKDVAGYDLTRLFVGSEGTLGVITEATLKLIPAPETKKTVLALYQDIDSAAQTVSNI
CHHHHHHCCCCEEEEEECCCCCEEEEEHEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
IAHKIIPTTLEFLDQPTIQVIEDFAKIGLPVHAKAVLLIEQDGTEDAVRRDIAVIEEICK
HHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHH
KGNAVSVQTAQTEAEAENLREARRTALSALARLKPTTILEDATVPRSEIAEMVKAINSIA
CCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCHHHHHHHHHHHHHHH
EKHQISICTFGHAGDGNLHPTCTTDVRNSEEMKRVEQAFEDIFKKAVELGGTITGEHGVG
HHHEEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCC
EMKAPYLELKLGNAGIAAMKAVKQALDPNNIMNPGKIFAKDSRKRVVVTR
CCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCEEECCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: (S)-2-hydroxy acid; O2

Specific reaction: (S)-2-hydroxy acid + O2 = 2-oxo acid + H2O2

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]