Click here to switch to the map view.

The map label for this gene is lysS [H]

Identifier: 52142901

GI number: 52142901

Start: 2471854

End: 2473407

Strand: Direct

Name: lysS [H]

Synonym: BCZK2340

Alternate gene names: 52142901

Gene position: 2471854-2473407 (Clockwise)

Preceding gene: 52142904

Following gene: 52142899

Centisome position: 46.63

GC content: 32.18

Gene sequence:

>1554_bases
ATGCATTGGGCGTATGAAGTAGCACACGAATTAATTAGAAAACATCCAAACAAAGAAACTTTTGTTTGTGCATCTGGAAT
TAGTCCATCAGGTTCTGTTCATATTGGGAACTTTCGTGAAATCGTAACGACTTATTTTGTTGTAAGGGCGCTTCAAGATT
TAGGGAAAAAGACTCGTTTTATATTTTCATGGGATGATTACGACAGGTTTAGAAAAGTCCCTAAAAATATTAATCCATCT
TTTGCGAAATATATTGGTATGCCATACTGTGATATTCCAGATCCATATGGTTGTCATAACTTTTATGCAGAGCATTTTGA
AAAAGAGTTTGAGGAATCGCTTCAAGTATTTGGGATTGAAGTGGAATTCATATATCAACATGCTGAATATAGAAGTGGAA
GATATAACAAAAACATATTGGAGGCTTTATATAAAAGAAAAGAAATATATGATATTTTAATGAGTTTTAAAACGGGAGAG
TGTAGTGAAGAAGAGCGAGAGGGCTTTTATCCGGTTACATTATATTGTGAGAAATGCGGGAAAGATGCGACAACGATTAC
ACATTTTGATGAAGTATTAAAAACAGTTCGGTATGAATGTGAATGCGGAAATCAAACTGAATTATCGGTATTAAATACAA
ATAAAATGAAACTGAATTGGAAAATCGATTGGCCGATGAGATGGATGATAGAGGATGTTGTTTTTGAGCCGGGCGGAAGA
GATCATTCATCAGAAACGGGTAGTTATAATGTATCAAAAGAAATTGCGAGAAAAATATTCAATCGTGAAGCGCCTCATTA
CATTGCTTACGATTTTATTGGAATTAAAGGGCATCATGAAAAAATGTCTAGTTCCTCAGGGAATAGTATTACACCTAGCG
AGTTGCTAAAAGTGTATTTGCCCGAAGTGATTCTATTTATGTTTGCAAAATATAGGCCAGACGCAGCGTTTCATATCGGT
CTTGATGAAGATGTAATTCGCAATTATACAGAATATGAACGATTGAAAGATAGTTATGAGAATAAAATGCTCAAAAATGA
AGATTTGTTTGATGCAATTAAACTTTCTAGAGCTGAGAGCGGATTTAAAGAATATCCGAAATTTAATCAAGTAGCTGGAA
CGTTGCCGTTATTACATTTTGACTCATTTATTTTACAGGGGATATTAGAGAAAATAGATAGGAGCTATGCATTAGATGAA
ATGAGATCGATAAGTAATCGTGCAGAATATTGGATAAGAAAATTTCGATCTGAAAAATTAATTGAGGTAAATCAGGAGAA
AAATACAGAGTTTTACAACACATTAGATAAAAGTCAGAAAGAATGGCTAGTAGAAGTTTGTGAAGTATTGCGTTTAAATA
AAGATTATTCAAACATAATGGAACAATTATATTCAATTTGTCATCATGAAAATAAAAAAATAATGAAAGAAAATCAAAAA
CAGTTATTCACTATTATATATATGCTCATTATAAATCAATCAAATGGTCCTCGTATATCATTATTAATACATGTGGTAGG
TATAGAAAAAAGCATCGCGTTATTAGATTTCTAA

Upstream 100 bases:

>100_bases
ACAACTCTCGTCCTCAAGATGAATAATCTTGGGGGTGGGAGTTTTTTTATTGTATAAAACTGAAAATCTGAAAACAAAAA
ACAATTGAGGTGAGTAACAT

Downstream 100 bases:

>100_bases
AACAAAGTTAAAAGCAACGCAAGTACCCAATTTTCTAGGTACTTGCGTTGCAAATTTTACTACCGTGAATACAATTTCGG
ACATTCATTACCACTAGGTT

Product: lysine--tRNA ligase, class I (lysyl-tRNA synthetase, class I)

Products: NA

Alternate protein names: Lysine--tRNA ligase; LysRS [H]

Number of amino acids: Translated: 517; Mature: 517

Protein sequence:

>517_residues
MHWAYEVAHELIRKHPNKETFVCASGISPSGSVHIGNFREIVTTYFVVRALQDLGKKTRFIFSWDDYDRFRKVPKNINPS
FAKYIGMPYCDIPDPYGCHNFYAEHFEKEFEESLQVFGIEVEFIYQHAEYRSGRYNKNILEALYKRKEIYDILMSFKTGE
CSEEEREGFYPVTLYCEKCGKDATTITHFDEVLKTVRYECECGNQTELSVLNTNKMKLNWKIDWPMRWMIEDVVFEPGGR
DHSSETGSYNVSKEIARKIFNREAPHYIAYDFIGIKGHHEKMSSSSGNSITPSELLKVYLPEVILFMFAKYRPDAAFHIG
LDEDVIRNYTEYERLKDSYENKMLKNEDLFDAIKLSRAESGFKEYPKFNQVAGTLPLLHFDSFILQGILEKIDRSYALDE
MRSISNRAEYWIRKFRSEKLIEVNQEKNTEFYNTLDKSQKEWLVEVCEVLRLNKDYSNIMEQLYSICHHENKKIMKENQK
QLFTIIYMLIINQSNGPRISLLIHVVGIEKSIALLDF

Sequences:

>Translated_517_residues
MHWAYEVAHELIRKHPNKETFVCASGISPSGSVHIGNFREIVTTYFVVRALQDLGKKTRFIFSWDDYDRFRKVPKNINPS
FAKYIGMPYCDIPDPYGCHNFYAEHFEKEFEESLQVFGIEVEFIYQHAEYRSGRYNKNILEALYKRKEIYDILMSFKTGE
CSEEEREGFYPVTLYCEKCGKDATTITHFDEVLKTVRYECECGNQTELSVLNTNKMKLNWKIDWPMRWMIEDVVFEPGGR
DHSSETGSYNVSKEIARKIFNREAPHYIAYDFIGIKGHHEKMSSSSGNSITPSELLKVYLPEVILFMFAKYRPDAAFHIG
LDEDVIRNYTEYERLKDSYENKMLKNEDLFDAIKLSRAESGFKEYPKFNQVAGTLPLLHFDSFILQGILEKIDRSYALDE
MRSISNRAEYWIRKFRSEKLIEVNQEKNTEFYNTLDKSQKEWLVEVCEVLRLNKDYSNIMEQLYSICHHENKKIMKENQK
QLFTIIYMLIINQSNGPRISLLIHVVGIEKSIALLDF
>Mature_517_residues
MHWAYEVAHELIRKHPNKETFVCASGISPSGSVHIGNFREIVTTYFVVRALQDLGKKTRFIFSWDDYDRFRKVPKNINPS
FAKYIGMPYCDIPDPYGCHNFYAEHFEKEFEESLQVFGIEVEFIYQHAEYRSGRYNKNILEALYKRKEIYDILMSFKTGE
CSEEEREGFYPVTLYCEKCGKDATTITHFDEVLKTVRYECECGNQTELSVLNTNKMKLNWKIDWPMRWMIEDVVFEPGGR
DHSSETGSYNVSKEIARKIFNREAPHYIAYDFIGIKGHHEKMSSSSGNSITPSELLKVYLPEVILFMFAKYRPDAAFHIG
LDEDVIRNYTEYERLKDSYENKMLKNEDLFDAIKLSRAESGFKEYPKFNQVAGTLPLLHFDSFILQGILEKIDRSYALDE
MRSISNRAEYWIRKFRSEKLIEVNQEKNTEFYNTLDKSQKEWLVEVCEVLRLNKDYSNIMEQLYSICHHENKKIMKENQK
QLFTIIYMLIINQSNGPRISLLIHVVGIEKSIALLDF

Specific function: Unknown

COG id: COG1384

COG function: function code J; Lysyl-tRNA synthetase (class I)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008925
- InterPro:   IPR020751
- InterPro:   IPR001412
- InterPro:   IPR002904
- InterPro:   IPR020754
- InterPro:   IPR020756
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01921 tRNA-synt_1f [H]

EC number: =6.1.1.6 [H]

Molecular weight: Translated: 60936; Mature: 60936

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHWAYEVAHELIRKHPNKETFVCASGISPSGSVHIGNFREIVTTYFVVRALQDLGKKTRF
CCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEECCHHHHHHHHHHHHHHHHHHCHHCEE
IFSWDDYDRFRKVPKNINPSFAKYIGMPYCDIPDPYGCHNFYAEHFEKEFEESLQVFGIE
EEECCCHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCEE
VEFIYQHAEYRSGRYNKNILEALYKRKEIYDILMSFKTGECSEEEREGFYPVTLYCEKCG
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCEEEEEEHHHC
KDATTITHFDEVLKTVRYECECGNQTELSVLNTNKMKLNWKIDWPMRWMIEDVVFEPGGR
CCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCEEEEEEEECCCHHHHHHHHHCCCCCC
DHSSETGSYNVSKEIARKIFNREAPHYIAYDFIGIKGHHEKMSSSSGNSITPSELLKVYL
CCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEEECCCCHHHHCCCCCCCCCHHHHHHHHH
PEVILFMFAKYRPDAAFHIGLDEDVIRNYTEYERLKDSYENKMLKNEDLFDAIKLSRAES
HHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHC
GFKEYPKFNQVAGTLPLLHFDSFILQGILEKIDRSYALDEMRSISNRAEYWIRKFRSEKL
CHHHCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
IEVNQEKNTEFYNTLDKSQKEWLVEVCEVLRLNKDYSNIMEQLYSICHHENKKIMKENQK
EECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHH
QLFTIIYMLIINQSNGPRISLLIHVVGIEKSIALLDF
HHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCCCCCC
>Mature Secondary Structure
MHWAYEVAHELIRKHPNKETFVCASGISPSGSVHIGNFREIVTTYFVVRALQDLGKKTRF
CCHHHHHHHHHHHHCCCCCEEEEECCCCCCCCEECCHHHHHHHHHHHHHHHHHHCHHCEE
IFSWDDYDRFRKVPKNINPSFAKYIGMPYCDIPDPYGCHNFYAEHFEKEFEESLQVFGIE
EEECCCHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCEE
VEFIYQHAEYRSGRYNKNILEALYKRKEIYDILMSFKTGECSEEEREGFYPVTLYCEKCG
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCCEEEEEEHHHC
KDATTITHFDEVLKTVRYECECGNQTELSVLNTNKMKLNWKIDWPMRWMIEDVVFEPGGR
CCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEECCEEEEEEEECCCHHHHHHHHHCCCCCC
DHSSETGSYNVSKEIARKIFNREAPHYIAYDFIGIKGHHEKMSSSSGNSITPSELLKVYL
CCCCCCCCCCHHHHHHHHHHCCCCCCEEEEEEEECCCCHHHHCCCCCCCCCHHHHHHHHH
PEVILFMFAKYRPDAAFHIGLDEDVIRNYTEYERLKDSYENKMLKNEDLFDAIKLSRAES
HHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHC
GFKEYPKFNQVAGTLPLLHFDSFILQGILEKIDRSYALDEMRSISNRAEYWIRKFRSEKL
CHHHCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
IEVNQEKNTEFYNTLDKSQKEWLVEVCEVLRLNKDYSNIMEQLYSICHHENKKIMKENQK
EECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHHH
QLFTIIYMLIINQSNGPRISLLIHVVGIEKSIALLDF
HHHHHHHHHHHCCCCCCEEEEEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9665876 [H]