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The map label for this gene is nrdR

Identifier: 51893899

GI number: 51893899

Start: 2980961

End: 2981413

Strand: Reverse

Name: nrdR

Synonym: STH2761

Alternate gene names: 51893899

Gene position: 2981413-2980961 (Counterclockwise)

Preceding gene: 51893900

Following gene: 51893898

Centisome position: 83.6

GC content: 64.46

Gene sequence:

>453_bases
ATGAAGTGCCCGTTCTGCGGAGGTGAGTCACGCGTCCTCGAATCCCGTCCCGCATCCGACGAGGAAGCCGTGCGTCGGCG
CCGGGAGTGCCTCGCCTGCGGGCGGCGTTTTACCACCATGGAGCGGGTGGAGGTGCCGCCGCTGATCGTGGTGAAGAAGG
ACGGCCGCCGGGAGCCCTTCAACCGGGACAAGCTCCTCACCGGCGTCCTGAAGGCCTGTGAGAAGCGTCCGGTGCCCATG
GAAGTGATCGAGAAGCTGGCCGACGACATCGAACGGGACCTGCGCTCTTCGCTGGACCGGGAGGTTCCTTCGGTGGTGAT
CGGCGAGCGGGTGATGGAGGCGCTGCGCCAGGTCGACGGCGTCGCGTACGTACGGTTTGCATCGGTATACAGGGAGTTTA
AGGATCTGAACGAGTTTCGGGAGCAGCTGGAACAGCTCTTGAAGTCCCGCTGA

Upstream 100 bases:

>100_bases
CGCGCGCCAAAGGTGCAAATTTGGCACCTGATCATGGTTGTCCCACCCCACATATGGTGGTAAAGTAGGACGTGCGATCA
CTAGATATGGGGGTTTCGCC

Downstream 100 bases:

>100_bases
AGCGGAGCGGCGCAGCGCGGAGGGAGCGCGCGCCCCGCGGACTCTACCAGAGGGGGGTTCCCGACTTGGAACTGACGCAT
ATTGCGAAGACCGTGATGGA

Product: transcriptional regulator NrdR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 150; Mature: 150

Protein sequence:

>150_residues
MKCPFCGGESRVLESRPASDEEAVRRRRECLACGRRFTTMERVEVPPLIVVKKDGRREPFNRDKLLTGVLKACEKRPVPM
EVIEKLADDIERDLRSSLDREVPSVVIGERVMEALRQVDGVAYVRFASVYREFKDLNEFREQLEQLLKSR

Sequences:

>Translated_150_residues
MKCPFCGGESRVLESRPASDEEAVRRRRECLACGRRFTTMERVEVPPLIVVKKDGRREPFNRDKLLTGVLKACEKRPVPM
EVIEKLADDIERDLRSSLDREVPSVVIGERVMEALRQVDGVAYVRFASVYREFKDLNEFREQLEQLLKSR
>Mature_150_residues
MKCPFCGGESRVLESRPASDEEAVRRRRECLACGRRFTTMERVEVPPLIVVKKDGRREPFNRDKLLTGVLKACEKRPVPM
EVIEKLADDIERDLRSSLDREVPSVVIGERVMEALRQVDGVAYVRFASVYREFKDLNEFREQLEQLLKSR

Specific function: Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes

COG id: COG1327

COG function: function code K; Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-cone domain

Homologues:

Organism=Escherichia coli, GI1786615, Length=147, Percent_Identity=48.9795918367347, Blast_Score=140, Evalue=3e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NRDR_SYMTH (Q67KQ1)

Other databases:

- EMBL:   AP006840
- RefSeq:   YP_076590.1
- GeneID:   2982123
- GenomeReviews:   AP006840_GR
- KEGG:   sth:STH2761
- NMPDR:   fig|292459.1.peg.2638
- HOGENOM:   HBG351755
- OMA:   FASVYRD
- ProtClustDB:   PRK00464
- BioCyc:   STHE292459:STH2761-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_00440
- InterPro:   IPR005144
- InterPro:   IPR003796
- TIGRFAMs:   TIGR00244

Pfam domain/function: PF03477 ATP-cone

EC number: NA

Molecular weight: Translated: 17426; Mature: 17426

Theoretical pI: Translated: 8.49; Mature: 8.49

Prosite motif: PS51161 ATP_CONE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKCPFCGGESRVLESRPASDEEAVRRRRECLACGRRFTTMERVEVPPLIVVKKDGRREPF
CCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCC
NRDKLLTGVLKACEKRPVPMEVIEKLADDIERDLRSSLDREVPSVVIGERVMEALRQVDG
CHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAYVRFASVYREFKDLNEFREQLEQLLKSR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKCPFCGGESRVLESRPASDEEAVRRRRECLACGRRFTTMERVEVPPLIVVKKDGRREPF
CCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCC
NRDKLLTGVLKACEKRPVPMEVIEKLADDIERDLRSSLDREVPSVVIGERVMEALRQVDG
CHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAYVRFASVYREFKDLNEFREQLEQLLKSR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA