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The map label for this gene is pheA [H]

Identifier: 51893830

GI number: 51893830

Start: 2881803

End: 2882675

Strand: Reverse

Name: pheA [H]

Synonym: STH2692

Alternate gene names: 51893830

Gene position: 2882675-2881803 (Counterclockwise)

Preceding gene: 51893832

Following gene: 51893829

Centisome position: 80.83

GC content: 66.44

Gene sequence:

>873_bases
ATGTGTGATAGAATGACCGAAAAATCCAGTTCGGGAGTGAACAGCATGCCGGTCGTCGCCTTCCAGGGGGAACTCGGGGC
CTATGGGGACGAGGCGGTGCGCGCCCGGTTCGGCCCCTCGGCGGAGCCGTATCCGTGCAAGTCCTTCGTCGACCTCTTCG
AGGCGGTGGCCAGCGGGACGGTGGACTACGGCCTGGCACCGGTGGAGAACTCCCAGGCCGGGTCGATCAATGACGTGTAT
GATCTGCTGCGCCAGTACGACCTGTACGTGGCCGGCGAGGTGCTCCACCCCGTGAACCACGCGCTGCTCGCCCTTCCCGG
GCAGACCCTGTCCGACATCCGCCGGGTCATCTCGCACCCGCAGGCGCTGGCCCAGTGCGACCGCTTCCTGCGGGATCTGG
GGGTGGAGGTGATGGCCACTTACGACACGGCCGGCGCGGCCAAGATGATCCGGGAGCAGGGCCTGACCGGCGTGGCGGCG
GTGGCCGGCCTGGGCGCGGCTCAACGGTATGGCCTTGCGGTGCTGGCGGAGTCGATCCAGACCATCAAGGACAACATCAC
CCGGTTCGTCGTGCTGCAGCGGGATCCGGCGCCCCGGGAGGAGGGGCCGCAGAAGACGATGCTCTTCCTGGCCCTGGCGC
ACCAGCCCGGCTCGCTCTACATGGCCCTGGGGGCCCTGGCCAACCGGAACATCAACCTGCTGAAGCTGGAGTCCCGGCCC
TCTCGGAACCGCCCGTGGGAGTACGTCTTCTACCTGGACTTCGAGGGGCACCGGGACGATCCGCACGTGCGCGCGGCATT
GGCCGATTTGGCAAAACATGCGAACTATTGTAAGGTATTGGGTTCATTCAGACGGGAAACGGTCCCGGACTAG

Upstream 100 bases:

>100_bases
GGACTGTTCGCTCTGTCATCACTATGGTTCCCATTTACCGTATACTCATACATATTCTCCCCACCCAATTCTGATACCGC
GCCGCTCGCCCCGCCTGCGG

Downstream 100 bases:

>100_bases
CAGGATTTCCACAGCGCGGGAGCGAACAGCAGAAATTGGCGTAACCCCCGCAAGGAGGAAAGCCGATTGGTTAAGAAAAT
CCTCATCGCTGACGCAGACC

Product: chorismate mutase/prephenate dehydratase

Products: NA

Alternate protein names: Chorismate mutase; CM; Prephenate dehydratase; PDT [H]

Number of amino acids: Translated: 290; Mature: 290

Protein sequence:

>290_residues
MCDRMTEKSSSGVNSMPVVAFQGELGAYGDEAVRARFGPSAEPYPCKSFVDLFEAVASGTVDYGLAPVENSQAGSINDVY
DLLRQYDLYVAGEVLHPVNHALLALPGQTLSDIRRVISHPQALAQCDRFLRDLGVEVMATYDTAGAAKMIREQGLTGVAA
VAGLGAAQRYGLAVLAESIQTIKDNITRFVVLQRDPAPREEGPQKTMLFLALAHQPGSLYMALGALANRNINLLKLESRP
SRNRPWEYVFYLDFEGHRDDPHVRAALADLAKHANYCKVLGSFRRETVPD

Sequences:

>Translated_290_residues
MCDRMTEKSSSGVNSMPVVAFQGELGAYGDEAVRARFGPSAEPYPCKSFVDLFEAVASGTVDYGLAPVENSQAGSINDVY
DLLRQYDLYVAGEVLHPVNHALLALPGQTLSDIRRVISHPQALAQCDRFLRDLGVEVMATYDTAGAAKMIREQGLTGVAA
VAGLGAAQRYGLAVLAESIQTIKDNITRFVVLQRDPAPREEGPQKTMLFLALAHQPGSLYMALGALANRNINLLKLESRP
SRNRPWEYVFYLDFEGHRDDPHVRAALADLAKHANYCKVLGSFRRETVPD
>Mature_290_residues
MCDRMTEKSSSGVNSMPVVAFQGELGAYGDEAVRARFGPSAEPYPCKSFVDLFEAVASGTVDYGLAPVENSQAGSINDVY
DLLRQYDLYVAGEVLHPVNHALLALPGQTLSDIRRVISHPQALAQCDRFLRDLGVEVMATYDTAGAAKMIREQGLTGVAA
VAGLGAAQRYGLAVLAESIQTIKDNITRFVVLQRDPAPREEGPQKTMLFLALAHQPGSLYMALGALANRNINLLKLESRP
SRNRPWEYVFYLDFEGHRDDPHVRAALADLAKHANYCKVLGSFRRETVPD

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=275, Percent_Identity=36.3636363636364, Blast_Score=169, Evalue=3e-43,
Organism=Saccharomyces cerevisiae, GI6324013, Length=320, Percent_Identity=25.3125, Blast_Score=89, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008242
- InterPro:   IPR002701
- InterPro:   IPR020822
- InterPro:   IPR010952
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01817 CM_2; PF00800 PDT [H]

EC number: =5.4.99.5; =4.2.1.51 [H]

Molecular weight: Translated: 31724; Mature: 31724

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCDRMTEKSSSGVNSMPVVAFQGELGAYGDEAVRARFGPSAEPYPCKSFVDLFEAVASGT
CCCCCCCCCCCCCCCCCEEEECCCCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHCCC
VDYGLAPVENSQAGSINDVYDLLRQYDLYVAGEVLHPVNHALLALPGQTLSDIRRVISHP
HHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHCC
QALAQCDRFLRDLGVEVMATYDTAGAAKMIREQGLTGVAAVAGLGAAQRYGLAVLAESIQ
HHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHH
TIKDNITRFVVLQRDPAPREEGPQKTMLFLALAHQPGSLYMALGALANRNINLLKLESRP
HHHHCCEEEEEEECCCCCCCCCCHHEEEEEEEECCCCHHHHHHHHHHCCCCEEEEECCCC
SRNRPWEYVFYLDFEGHRDDPHVRAALADLAKHANYCKVLGSFRRETVPD
CCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MCDRMTEKSSSGVNSMPVVAFQGELGAYGDEAVRARFGPSAEPYPCKSFVDLFEAVASGT
CCCCCCCCCCCCCCCCCEEEECCCCCCCCCHHHHHHCCCCCCCCCHHHHHHHHHHHHCCC
VDYGLAPVENSQAGSINDVYDLLRQYDLYVAGEVLHPVNHALLALPGQTLSDIRRVISHP
HHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHCC
QALAQCDRFLRDLGVEVMATYDTAGAAKMIREQGLTGVAAVAGLGAAQRYGLAVLAESIQ
HHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHH
TIKDNITRFVVLQRDPAPREEGPQKTMLFLALAHQPGSLYMALGALANRNINLLKLESRP
HHHHCCEEEEEEECCCCCCCCCCHHEEEEEEEECCCCHHHHHHHHHHCCCCEEEEECCCC
SRNRPWEYVFYLDFEGHRDDPHVRAALADLAKHANYCKVLGSFRRETVPD
CCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]