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The map label for this gene is cysN

Identifier: 51595116

GI number: 51595116

Start: 922657

End: 924093

Strand: Direct

Name: cysN

Synonym: YPTB0766

Alternate gene names: 51595116

Gene position: 922657-924093 (Clockwise)

Preceding gene: 51595115

Following gene: 51595117

Centisome position: 19.45

GC content: 51.29

Gene sequence:

>1437_bases
ATGATTTTACAGAGCAACTCGATTGCACAGCAAATTGCTGATGAAGGCGGAGTTGAAGCCTACTTACATGCTCAGCAGCA
TAAAACCATGCTGCGTTTTCTGACCTGTGGCAGCGTGGATGATGGCAAAAGTACCTTAATCGGTCGCTTGCTGCATGATA
CCCGCCAAATCTACGAAGATCAGCTCTCGACGCTGCACACTGACAGCAAGCGTATCGGTACACAGGGTGAAAAACTGGAC
CTGGCCTTGCTGGTGGATGGCTTGCAGGCCGAACGCGAACAGGGCATTACCATTGATGTGGCTTATCGTTATTTTTCGAC
GGAAAAGCGCAAATTTATCATTGCCGATACCCCTGGGCATGAGCAATACACTCGCAATATGGCCACCGGTGCGTCTACCT
GTGATCTGGCGATCCTGTTGATCGATGCGCGCAAAGGGGTGTTGGATCAAACCCGTCGCCACAGCTTTATCGCCACCTTG
TTGGGGATTCGTCATCTCGTGGTCGCGGTGAACAAGATGGATCTGGTGGGTTTCCAAGAGAGTGTCTTCACGCAATTTAA
AGACGATTACCTCAGTTTCGCGGAACAATTACCCACTGATCTGGACATTAAATTTGTCCCGCTCTCGGCTCTGGATGGCG
ACAACGTAGCATCGCCCAGCGAGAAAATGGATTGGTATTCTGGCCCCACGCTGCTTGAAATATTAGAAAGTGTTGATGTC
GTTAATGCCCGCCGTCAGCAGCCCTTGCGCTTCCCAGTGCAATACGTCAACCGGCCCAATCTGGATTTCCGTGGCTATGC
CGGTACCTTGTCAGCAGGCGTGGTGTGGGTTGGGCAAAAAGTGAAAGTCTTGCCATCCGGTGTGGAATCTACCGTTGCGC
GCATCGTCACTTTTGATGGTGACCTGACGGAAGCGAATCCTGGTGAGGCCATTACGCTGGTTCTGGCTGATGAAGTGGAT
ATCAGCCGCGGCGACTTACTGGTGGATGCCAGCGAAACGCTGAAAGCGGCCCGGAACGCGTTGGTTGATGTGGTATGGAT
GGCCGAGCAACCGTTGGTCGTCGGGCAAAGTTATGACATCAAAGTGGCGGGTAAAAAGACCCGAGCGCGGGTTGAAAACA
TTCAATATCAGGTGGAAATCAATTCACTGACCCAACGGGTCGTGGAAAATTTACCGTTGAATGGTATTGGTCTGGTTGAA
CTGGCATTCGATGAACCTTTATTACTGGATAACTATCAGCGCAACCGTGATACCGGTGGCATGATTTTTATTGATCGGCT
GAGTAATGTCACTGTCGGTGCGGGGTTGGTCCGTGAAGCGCTGGCGTCGGTTTATCAGGAGAATCATGACTTCAGTACCT
TTGAGCTGGAATTAAATGCCTTGGTTCGCCGTCATTTCCCACATTGGGGTGCGCGTGATCTGCTGGGGGGTAAATAG

Upstream 100 bases:

>100_bases
ATTTCTGAGGAGCGGCCCGATGAGCACGATATTGCAAAACAAGCAGACATTACCAAGTGAACCTATTGCTAAAAATCAGT
CAGCATTAGAAAGTAACTCA

Downstream 100 bases:

>100_bases
CGTGCCAGCCCATCAGTTAGATGACCATAACCAAGAAACGCGGTCAGACGATGAGAATATCGTCTGGCACCCCCATGCGA
TCACCCGACAGGATCGCGAA

Product: sulfate adenylyltransferase subunit 1

Products: NA

Alternate protein names: ATP-sulfurylase large subunit; Sulfate adenylate transferase; SAT [H]

Number of amino acids: Translated: 478; Mature: 478

Protein sequence:

>478_residues
MILQSNSIAQQIADEGGVEAYLHAQQHKTMLRFLTCGSVDDGKSTLIGRLLHDTRQIYEDQLSTLHTDSKRIGTQGEKLD
LALLVDGLQAEREQGITIDVAYRYFSTEKRKFIIADTPGHEQYTRNMATGASTCDLAILLIDARKGVLDQTRRHSFIATL
LGIRHLVVAVNKMDLVGFQESVFTQFKDDYLSFAEQLPTDLDIKFVPLSALDGDNVASPSEKMDWYSGPTLLEILESVDV
VNARRQQPLRFPVQYVNRPNLDFRGYAGTLSAGVVWVGQKVKVLPSGVESTVARIVTFDGDLTEANPGEAITLVLADEVD
ISRGDLLVDASETLKAARNALVDVVWMAEQPLVVGQSYDIKVAGKKTRARVENIQYQVEINSLTQRVVENLPLNGIGLVE
LAFDEPLLLDNYQRNRDTGGMIFIDRLSNVTVGAGLVREALASVYQENHDFSTFELELNALVRRHFPHWGARDLLGGK

Sequences:

>Translated_478_residues
MILQSNSIAQQIADEGGVEAYLHAQQHKTMLRFLTCGSVDDGKSTLIGRLLHDTRQIYEDQLSTLHTDSKRIGTQGEKLD
LALLVDGLQAEREQGITIDVAYRYFSTEKRKFIIADTPGHEQYTRNMATGASTCDLAILLIDARKGVLDQTRRHSFIATL
LGIRHLVVAVNKMDLVGFQESVFTQFKDDYLSFAEQLPTDLDIKFVPLSALDGDNVASPSEKMDWYSGPTLLEILESVDV
VNARRQQPLRFPVQYVNRPNLDFRGYAGTLSAGVVWVGQKVKVLPSGVESTVARIVTFDGDLTEANPGEAITLVLADEVD
ISRGDLLVDASETLKAARNALVDVVWMAEQPLVVGQSYDIKVAGKKTRARVENIQYQVEINSLTQRVVENLPLNGIGLVE
LAFDEPLLLDNYQRNRDTGGMIFIDRLSNVTVGAGLVREALASVYQENHDFSTFELELNALVRRHFPHWGARDLLGGK
>Mature_478_residues
MILQSNSIAQQIADEGGVEAYLHAQQHKTMLRFLTCGSVDDGKSTLIGRLLHDTRQIYEDQLSTLHTDSKRIGTQGEKLD
LALLVDGLQAEREQGITIDVAYRYFSTEKRKFIIADTPGHEQYTRNMATGASTCDLAILLIDARKGVLDQTRRHSFIATL
LGIRHLVVAVNKMDLVGFQESVFTQFKDDYLSFAEQLPTDLDIKFVPLSALDGDNVASPSEKMDWYSGPTLLEILESVDV
VNARRQQPLRFPVQYVNRPNLDFRGYAGTLSAGVVWVGQKVKVLPSGVESTVARIVTFDGDLTEANPGEAITLVLADEVD
ISRGDLLVDASETLKAARNALVDVVWMAEQPLVVGQSYDIKVAGKKTRARVENIQYQVEINSLTQRVVENLPLNGIGLVE
LAFDEPLLLDNYQRNRDTGGMIFIDRLSNVTVGAGLVREALASVYQENHDFSTFELELNALVRRHFPHWGARDLLGGK

Specific function: May be the GTPase, regulating ATP sulfurylase activity [H]

COG id: COG2895

COG function: function code P; GTPases - Sulfate adenylate transferase subunit 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. CysN/nodQ subfamily [H]

Homologues:

Organism=Homo sapiens, GI223555963, Length=455, Percent_Identity=28.3516483516484, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI5729864, Length=455, Percent_Identity=28.3516483516484, Blast_Score=157, Evalue=2e-38,
Organism=Homo sapiens, GI46094014, Length=333, Percent_Identity=30.3303303303303, Blast_Score=152, Evalue=5e-37,
Organism=Homo sapiens, GI4503475, Length=436, Percent_Identity=25.6880733944954, Blast_Score=152, Evalue=9e-37,
Organism=Homo sapiens, GI194018522, Length=333, Percent_Identity=30.03003003003, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI194018520, Length=333, Percent_Identity=30.03003003003, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI194097354, Length=333, Percent_Identity=30.03003003003, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI4503471, Length=329, Percent_Identity=30.3951367781155, Blast_Score=150, Evalue=3e-36,
Organism=Homo sapiens, GI34147630, Length=455, Percent_Identity=26.8131868131868, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI157426893, Length=223, Percent_Identity=28.6995515695067, Blast_Score=68, Evalue=2e-11,
Organism=Escherichia coli, GI1789108, Length=474, Percent_Identity=79.1139240506329, Blast_Score=773, Evalue=0.0,
Organism=Escherichia coli, GI1790412, Length=434, Percent_Identity=24.4239631336406, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1789737, Length=434, Percent_Identity=24.4239631336406, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI2367247, Length=93, Percent_Identity=38.7096774193548, Blast_Score=63, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17552884, Length=437, Percent_Identity=28.604118993135, Blast_Score=167, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI17569207, Length=437, Percent_Identity=28.604118993135, Blast_Score=167, Evalue=2e-41,
Organism=Caenorhabditis elegans, GI115532067, Length=430, Percent_Identity=27.4418604651163, Blast_Score=152, Evalue=5e-37,
Organism=Caenorhabditis elegans, GI115532065, Length=430, Percent_Identity=27.4418604651163, Blast_Score=151, Evalue=8e-37,
Organism=Caenorhabditis elegans, GI32566629, Length=431, Percent_Identity=26.4501160092807, Blast_Score=142, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI32566303, Length=430, Percent_Identity=27.2093023255814, Blast_Score=139, Evalue=5e-33,
Organism=Caenorhabditis elegans, GI32566301, Length=149, Percent_Identity=34.8993288590604, Blast_Score=89, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI25141371, Length=236, Percent_Identity=27.1186440677966, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17556456, Length=343, Percent_Identity=26.8221574344023, Blast_Score=86, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6325337, Length=327, Percent_Identity=31.1926605504587, Blast_Score=158, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6319594, Length=327, Percent_Identity=31.1926605504587, Blast_Score=158, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6322937, Length=447, Percent_Identity=28.6353467561521, Blast_Score=152, Evalue=9e-38,
Organism=Saccharomyces cerevisiae, GI6320377, Length=327, Percent_Identity=30.8868501529052, Blast_Score=125, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6324761, Length=144, Percent_Identity=36.1111111111111, Blast_Score=85, Evalue=2e-17,
Organism=Drosophila melanogaster, GI45550900, Length=429, Percent_Identity=26.8065268065268, Blast_Score=155, Evalue=4e-38,
Organism=Drosophila melanogaster, GI17137380, Length=319, Percent_Identity=30.4075235109718, Blast_Score=154, Evalue=1e-37,
Organism=Drosophila melanogaster, GI45553807, Length=308, Percent_Identity=30.8441558441558, Blast_Score=149, Evalue=4e-36,
Organism=Drosophila melanogaster, GI45553816, Length=308, Percent_Identity=30.8441558441558, Blast_Score=149, Evalue=4e-36,
Organism=Drosophila melanogaster, GI24651721, Length=308, Percent_Identity=30.8441558441558, Blast_Score=149, Evalue=4e-36,
Organism=Drosophila melanogaster, GI17864154, Length=308, Percent_Identity=30.8441558441558, Blast_Score=149, Evalue=4e-36,
Organism=Drosophila melanogaster, GI24652838, Length=436, Percent_Identity=25.4587155963303, Blast_Score=142, Evalue=6e-34,
Organism=Drosophila melanogaster, GI17137572, Length=436, Percent_Identity=25.4587155963303, Blast_Score=142, Evalue=6e-34,
Organism=Drosophila melanogaster, GI281363316, Length=431, Percent_Identity=25.754060324826, Blast_Score=95, Evalue=9e-20,
Organism=Drosophila melanogaster, GI17864358, Length=431, Percent_Identity=25.754060324826, Blast_Score=95, Evalue=9e-20,
Organism=Drosophila melanogaster, GI19921738, Length=239, Percent_Identity=25.9414225941423, Blast_Score=80, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000795
- InterPro:   IPR005225
- InterPro:   IPR011779
- InterPro:   IPR009001
- InterPro:   IPR004161
- InterPro:   IPR009000 [H]

Pfam domain/function: PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: =2.7.7.4 [H]

Molecular weight: Translated: 53071; Mature: 53071

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS00301 EFACTOR_GTP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILQSNSIAQQIADEGGVEAYLHAQQHKTMLRFLTCGSVDDGKSTLIGRLLHDTRQIYED
CEECCCHHHHHHHHCCCCEEEEEHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
QLSTLHTDSKRIGTQGEKLDLALLVDGLQAEREQGITIDVAYRYFSTEKRKFIIADTPGH
HHHHHCCCCHHCCCCCCCEEEEEEECCHHHHHHCCCEEEEEEEEECCCCCEEEEEECCCC
EQYTRNMATGASTCDLAILLIDARKGVLDQTRRHSFIATLLGIRHLVVAVNKMDLVGFQE
HHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
SVFTQFKDDYLSFAEQLPTDLDIKFVPLSALDGDNVASPSEKMDWYSGPTLLEILESVDV
HHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCHHHCCCCCCCHHHHHHHHHHH
VNARRQQPLRFPVQYVNRPNLDFRGYAGTLSAGVVWVGQKVKVLPSGVESTVARIVTFDG
HHHHHCCCCCCCHHHCCCCCCCCCCCCCCCCCCEEEECCEEEECCCCHHHHHHEEEEECC
DLTEANPGEAITLVLADEVDISRGDLLVDASETLKAARNALVDVVWMAEQPLVVGQSYDI
CCCCCCCCCEEEEEEECCCCCCCCCEEEECHHHHHHHHHHHEEEEEECCCCEEECCCEEE
KVAGKKTRARVENIQYQVEINSLTQRVVENLPLNGIGLVELAFDEPLLLDNYQRNRDTGG
EECCCHHHHHHHCEEEEEEHHHHHHHHHHHCCCCCCEEEEEECCCCEEECCCCCCCCCCC
MIFIDRLSNVTVGAGLVREALASVYQENHDFSTFELELNALVRRHFPHWGARDLLGGK
EEEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MILQSNSIAQQIADEGGVEAYLHAQQHKTMLRFLTCGSVDDGKSTLIGRLLHDTRQIYED
CEECCCHHHHHHHHCCCCEEEEEHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHH
QLSTLHTDSKRIGTQGEKLDLALLVDGLQAEREQGITIDVAYRYFSTEKRKFIIADTPGH
HHHHHCCCCHHCCCCCCCEEEEEEECCHHHHHHCCCEEEEEEEEECCCCCEEEEEECCCC
EQYTRNMATGASTCDLAILLIDARKGVLDQTRRHSFIATLLGIRHLVVAVNKMDLVGFQE
HHHHHHHHCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
SVFTQFKDDYLSFAEQLPTDLDIKFVPLSALDGDNVASPSEKMDWYSGPTLLEILESVDV
HHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCHHHCCCCCCCHHHHHHHHHHH
VNARRQQPLRFPVQYVNRPNLDFRGYAGTLSAGVVWVGQKVKVLPSGVESTVARIVTFDG
HHHHHCCCCCCCHHHCCCCCCCCCCCCCCCCCCEEEECCEEEECCCCHHHHHHEEEEECC
DLTEANPGEAITLVLADEVDISRGDLLVDASETLKAARNALVDVVWMAEQPLVVGQSYDI
CCCCCCCCCEEEEEEECCCCCCCCCEEEECHHHHHHHHHHHEEEEEECCCCEEECCCEEE
KVAGKKTRARVENIQYQVEINSLTQRVVENLPLNGIGLVELAFDEPLLLDNYQRNRDTGG
EECCCHHHHHHHCEEEEEEHHHHHHHHHHHCCCCCCEEEEEECCCCEEECCCCCCCCCCC
MIFIDRLSNVTVGAGLVREALASVYQENHDFSTFELELNALVRRHFPHWGARDLLGGK
EEEEEECCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA