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The map label for this gene is yicO [H]

Identifier: 50841963

GI number: 50841963

Start: 529719

End: 531230

Strand: Direct

Name: yicO [H]

Synonym: PPA0480

Alternate gene names: 50841963

Gene position: 529719-531230 (Clockwise)

Preceding gene: 50841961

Following gene: 50841965

Centisome position: 20.69

GC content: 57.87

Gene sequence:

>1512_bases
GTGCCTAGCAACACCGCATCAGCAAGATTTGATCAGTGGTTCCATCTGACAGAACGTGGTTCGACGACGTCGCGCGAAGT
TCGCGGCGGCATCGTCACCTTCTTCACGATGGCATACATCCTGGCTCTCAATCCTCTCATCATCGGTACCGCAGCGGATA
AGAATGGCAAACTCCTCAATGGAGCTCCGAAATTCCTCGACGCTGCTGGCACCAGCCTTAATACTGCTGGCATTGATGAC
AACAAAATCATGGTGATGGCAGTGACTGCCTTCGTGGCTGCCATCATGACGATTGCTATGGGTGTCTGGGGACGATTCCC
GATGGGTATCGCAACAGGCCTGGGCATTAACTCCCTGCTTGCCTACGTCGTCGCCCCGACGATGACGTGGTCTCAGGCGA
TGGGTTTGGTTGTCTGGGAGGGCATCTTCATTCTGGTGTTCGTCCTTACTGGTGTCCGGGAAATGATTTTCCGGGCTGTC
CCTAATTCCTTGCGGTCGGCGATCAGTGTTGGAATTGGCCTGTTCATCGCTTTTGTGGGATTTGTGGATTCTGGCGTGAT
TCGCCCTGGCTCGGGTACCCCTGTCACCCTCGGAGTTGGTGGCAGCTTGGAGGGGTGGCCAATCTTGCTGTGCCTGTTCG
GTTTCCTGTTGCTGGTGGTGTTGCATCAGCGTCACATCAAAGGGTCTATGCTCATCGCGATCATTGGCACCTCACTGGTG
GGTGTGGCCATCGAGGCCGTGGGGAACATCGGTGCGCAAAGTGACAAGAACCCCACTGGCTGGGCCCTCAACGTGCCCCG
TCTGCCCGGCGCCTCGGATTTCCGCTGGCCCGATCTGGGCTTGCTCGGTCATGTTGACCTCTTTGGTGGGTTCCTTGCCA
ACGGGCACTTTCGTATTGGTGTCTTCTTGGGCACCCTGCTGGTGGTGTTCTCCCTGATGCTTGCCGACTTCTTCGACACC
ATGGGGACGGTTGTTGCGATCGGTGACCACGCCGGGCTTCTTGACGAGACCGGCAATCCTGAGCACCTCAAGGGAATCCT
GGTCGTTGACGCCTTGGCCGCGGTGGCTGGCGGTCTTGGCTCGGCGTCGTCGGCAACGGGTTACGTCGAGTCGGCTGCTG
GCGTGGGAGAGGGAGCCCGCACAGGTATCGCCTCCATCGTCACCGGTCTGGGATTCCTGCTGGCGATGTTCCTGTCGCCA
ATCGTTTCGATCATCCCGTCCGAAGCAGCCGCACCGGTGCTTGTTTTCGTCGGGTTCCTCATGATGGCTCAGGTCACGCG
CATTGACTGGAAGCACGTTGAGGAAGGCCTACCGGCCTTCCTAGGCATGGTGCTTATGCCGTTCGCCTACTCGATCACTA
CAGGTATCGGAGCTGGACTCATCATGTTCTGCATCACGAAGGTCATCGCTGGTAAAGCTCGCAGCGTGCATCCTCTGCTG
TGGGTCGTTGCCCTCCTCTTTGTGGTGTATTTCAGCCAGACCCTCCTCATGAAGCTGTTCGGCCAGCTCTGA

Upstream 100 bases:

>100_bases
CGGGTGCGACGTTCGCCTGGGTAAGCAGGTGATGGTTGGACACCGCTCCATCGTAATGCCCTGCAACATTGTTGTGACAC
GTCATCCCTAGAATGCCTCC

Downstream 100 bases:

>100_bases
GACCAGTGGGGTGGGCGTCTTCGACGGTGTCCGGCTGCCAGACCACTAAGAGGCCTGGCGCCGGGCGGCCCAGATCGACT
GCGAGATGATTCCACCCCGG

Product: putative xanthine/uracil permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 503; Mature: 502

Protein sequence:

>503_residues
MPSNTASARFDQWFHLTERGSTTSREVRGGIVTFFTMAYILALNPLIIGTAADKNGKLLNGAPKFLDAAGTSLNTAGIDD
NKIMVMAVTAFVAAIMTIAMGVWGRFPMGIATGLGINSLLAYVVAPTMTWSQAMGLVVWEGIFILVFVLTGVREMIFRAV
PNSLRSAISVGIGLFIAFVGFVDSGVIRPGSGTPVTLGVGGSLEGWPILLCLFGFLLLVVLHQRHIKGSMLIAIIGTSLV
GVAIEAVGNIGAQSDKNPTGWALNVPRLPGASDFRWPDLGLLGHVDLFGGFLANGHFRIGVFLGTLLVVFSLMLADFFDT
MGTVVAIGDHAGLLDETGNPEHLKGILVVDALAAVAGGLGSASSATGYVESAAGVGEGARTGIASIVTGLGFLLAMFLSP
IVSIIPSEAAAPVLVFVGFLMMAQVTRIDWKHVEEGLPAFLGMVLMPFAYSITTGIGAGLIMFCITKVIAGKARSVHPLL
WVVALLFVVYFSQTLLMKLFGQL

Sequences:

>Translated_503_residues
MPSNTASARFDQWFHLTERGSTTSREVRGGIVTFFTMAYILALNPLIIGTAADKNGKLLNGAPKFLDAAGTSLNTAGIDD
NKIMVMAVTAFVAAIMTIAMGVWGRFPMGIATGLGINSLLAYVVAPTMTWSQAMGLVVWEGIFILVFVLTGVREMIFRAV
PNSLRSAISVGIGLFIAFVGFVDSGVIRPGSGTPVTLGVGGSLEGWPILLCLFGFLLLVVLHQRHIKGSMLIAIIGTSLV
GVAIEAVGNIGAQSDKNPTGWALNVPRLPGASDFRWPDLGLLGHVDLFGGFLANGHFRIGVFLGTLLVVFSLMLADFFDT
MGTVVAIGDHAGLLDETGNPEHLKGILVVDALAAVAGGLGSASSATGYVESAAGVGEGARTGIASIVTGLGFLLAMFLSP
IVSIIPSEAAAPVLVFVGFLMMAQVTRIDWKHVEEGLPAFLGMVLMPFAYSITTGIGAGLIMFCITKVIAGKARSVHPLL
WVVALLFVVYFSQTLLMKLFGQL
>Mature_502_residues
PSNTASARFDQWFHLTERGSTTSREVRGGIVTFFTMAYILALNPLIIGTAADKNGKLLNGAPKFLDAAGTSLNTAGIDDN
KIMVMAVTAFVAAIMTIAMGVWGRFPMGIATGLGINSLLAYVVAPTMTWSQAMGLVVWEGIFILVFVLTGVREMIFRAVP
NSLRSAISVGIGLFIAFVGFVDSGVIRPGSGTPVTLGVGGSLEGWPILLCLFGFLLLVVLHQRHIKGSMLIAIIGTSLVG
VAIEAVGNIGAQSDKNPTGWALNVPRLPGASDFRWPDLGLLGHVDLFGGFLANGHFRIGVFLGTLLVVFSLMLADFFDTM
GTVVAIGDHAGLLDETGNPEHLKGILVVDALAAVAGGLGSASSATGYVESAAGVGEGARTGIASIVTGLGFLLAMFLSPI
VSIIPSEAAAPVLVFVGFLMMAQVTRIDWKHVEEGLPAFLGMVLMPFAYSITTGIGAGLIMFCITKVIAGKARSVHPLLW
VVALLFVVYFSQTLLMKLFGQL

Specific function: Unknown

COG id: COG2252

COG function: function code R; Permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. AzgA purine transporter (TC 2.A.1.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87082309, Length=487, Percent_Identity=34.2915811088296, Blast_Score=259, Evalue=4e-70,
Organism=Escherichia coli, GI1790150, Length=481, Percent_Identity=34.7193347193347, Blast_Score=254, Evalue=1e-68,
Organism=Escherichia coli, GI1790499, Length=495, Percent_Identity=28.2828282828283, Blast_Score=182, Evalue=5e-47,
Organism=Escherichia coli, GI48994909, Length=473, Percent_Identity=27.4841437632135, Blast_Score=149, Evalue=5e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 52746; Mature: 52615

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSNTASARFDQWFHLTERGSTTSREVRGGIVTFFTMAYILALNPLIIGTAADKNGKLLN
CCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCC
GAPKFLDAAGTSLNTAGIDDNKIMVMAVTAFVAAIMTIAMGVWGRFPMGIATGLGINSLL
CCHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHH
AYVVAPTMTWSQAMGLVVWEGIFILVFVLTGVREMIFRAVPNSLRSAISVGIGLFIAFVG
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
FVDSGVIRPGSGTPVTLGVGGSLEGWPILLCLFGFLLLVVLHQRHIKGSMLIAIIGTSLV
HHHCCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
GVAIEAVGNIGAQSDKNPTGWALNVPRLPGASDFRWPDLGLLGHVDLFGGFLANGHFRIG
HHHHHHHHCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHH
VFLGTLLVVFSLMLADFFDTMGTVVAIGDHAGLLDETGNPEHLKGILVVDALAAVAGGLG
HHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCC
SASSATGYVESAAGVGEGARTGIASIVTGLGFLLAMFLSPIVSIIPSEAAAPVLVFVGFL
CCCCCCCHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
MMAQVTRIDWKHVEEGLPAFLGMVLMPFAYSITTGIGAGLIMFCITKVIAGKARSVHPLL
HHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
WVVALLFVVYFSQTLLMKLFGQL
HHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PSNTASARFDQWFHLTERGSTTSREVRGGIVTFFTMAYILALNPLIIGTAADKNGKLLN
CCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCC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HHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503 [H]