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The map label for this gene is desR [H]

Identifier: 50841898

GI number: 50841898

Start: 459502

End: 460122

Strand: Direct

Name: desR [H]

Synonym: PPA0416

Alternate gene names: 50841898

Gene position: 459502-460122 (Clockwise)

Preceding gene: 50841897

Following gene: 50841900

Centisome position: 17.95

GC content: 64.09

Gene sequence:

>621_bases
ATGATCGACAAGACCCCGATCAGACTCGTGCTAGCCGACGACCAGACCCTTGTACGCGGAGCTCTGGCAGCCCTGCTCGG
CATGGAGGACGACCTGGAGATCGTCGGCACGTGCGGGCGAGGTGACGAGGTGGTTGGCCTGGTGCAGGATACTTACGCTG
ACGTGTGTTTGCTCGACATCGAGATGCCTGGTCTTGACGGGATCACGGTCGCCGCCGAGCTGAGGGACCAGGCGCCGTGG
TGTCGAATTCTCATCGTGACGACCTTCGGGCGACCGGGATATCTGCGGCGAGCCATGGACGCCGGTGTGGCTGGATTCCT
TGTTAAAGACACCCCTGCCGAGGTTCTGGCCCAGGTGGTGCGCAAGGTCCACGCCGGAGGTAGGGCCATCGACCCGGCCT
TGGCCGCTGAATCCCTCATCGAGGGTCACAATCCCTTGTCAGGCCGGGAACGGGAGATCCTGCGGCTGGCCGAGTCGGGA
GCATCGATCTCCCTCATCGCTTCCGAGCTGTGCCTGTCAGTGGGTACGGTGCGTAACCACGTGTCCTCGGCTATTGGCAA
GACGGGCGCGGCGAATCGCACTGAGGCGGCTGTCACGGCTCGACGTCGGGGGTGGCTGTGA

Upstream 100 bases:

>100_bases
ACGGGTATGCGTCGACGGGTTGAGGCAGCCGGGGGAGAGTTGTGGATCGGGCCGGGGGAGCGTGGCCACGGTACCCGGAT
TGTCGTGACAGGCTGAGGCC

Downstream 100 bases:

>100_bases
GGGTCGTCGTTCGTGATGTGGCCCAGATCATTGCTCGTCGGCAGGGATGCAGCCAGCCAACAGTCTGACATCGCCAAGGC
TGAGAGTATGACGCAGATTG

Product: two-component system response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 206; Mature: 206

Protein sequence:

>206_residues
MIDKTPIRLVLADDQTLVRGALAALLGMEDDLEIVGTCGRGDEVVGLVQDTYADVCLLDIEMPGLDGITVAAELRDQAPW
CRILIVTTFGRPGYLRRAMDAGVAGFLVKDTPAEVLAQVVRKVHAGGRAIDPALAAESLIEGHNPLSGREREILRLAESG
ASISLIASELCLSVGTVRNHVSSAIGKTGAANRTEAAVTARRRGWL

Sequences:

>Translated_206_residues
MIDKTPIRLVLADDQTLVRGALAALLGMEDDLEIVGTCGRGDEVVGLVQDTYADVCLLDIEMPGLDGITVAAELRDQAPW
CRILIVTTFGRPGYLRRAMDAGVAGFLVKDTPAEVLAQVVRKVHAGGRAIDPALAAESLIEGHNPLSGREREILRLAESG
ASISLIASELCLSVGTVRNHVSSAIGKTGAANRTEAAVTARRRGWL
>Mature_206_residues
MIDKTPIRLVLADDQTLVRGALAALLGMEDDLEIVGTCGRGDEVVGLVQDTYADVCLLDIEMPGLDGITVAAELRDQAPW
CRILIVTTFGRPGYLRRAMDAGVAGFLVKDTPAEVLAQVVRKVHAGGRAIDPALAAESLIEGHNPLSGREREILRLAESG
ASISLIASELCLSVGTVRNHVSSAIGKTGAANRTEAAVTARRRGWL

Specific function: Member of the two-component regulatory system desR/desK, responsible for cold induction of the des gene coding for the Delta5 acyl-lipid desaturase [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790102, Length=202, Percent_Identity=33.1683168316832, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1787473, Length=208, Percent_Identity=29.8076923076923, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1788521, Length=206, Percent_Identity=27.6699029126214, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788222, Length=207, Percent_Identity=25.6038647342995, Blast_Score=73, Evalue=1e-14,
Organism=Escherichia coli, GI1786747, Length=192, Percent_Identity=26.0416666666667, Blast_Score=67, Evalue=7e-13,
Organism=Escherichia coli, GI1788546, Length=210, Percent_Identity=25.2380952380952, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011990
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 21806; Mature: 21806

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDKTPIRLVLADDQTLVRGALAALLGMEDDLEIVGTCGRGDEVVGLVQDTYADVCLLDI
CCCCCCEEEEEECCHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEHHHHHCCCEEEEEE
EMPGLDGITVAAELRDQAPWCRILIVTTFGRPGYLRRAMDAGVAGFLVKDTPAEVLAQVV
ECCCCCCEEEEEHHHCCCCEEEEEEEEECCCCHHHHHHHHCCCEEEEECCCHHHHHHHHH
RKVHAGGRAIDPALAAESLIEGHNPLSGREREILRLAESGASISLIASELCLSVGTVRNH
HHHHCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
VSSAIGKTGAANRTEAAVTARRRGWL
HHHHHCCCCCCCCHHHHHHHHHCCCC
>Mature Secondary Structure
MIDKTPIRLVLADDQTLVRGALAALLGMEDDLEIVGTCGRGDEVVGLVQDTYADVCLLDI
CCCCCCEEEEEECCHHHHHHHHHHHHCCCCCCEEEEECCCCCCEEEHHHHHCCCEEEEEE
EMPGLDGITVAAELRDQAPWCRILIVTTFGRPGYLRRAMDAGVAGFLVKDTPAEVLAQVV
ECCCCCCEEEEEHHHCCCCEEEEEEEEECCCCHHHHHHHHCCCEEEEECCCHHHHHHHHH
RKVHAGGRAIDPALAAESLIEGHNPLSGREREILRLAESGASISLIASELCLSVGTVRNH
HHHHCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
VSSAIGKTGAANRTEAAVTARRRGWL
HHHHHCCCCCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]